We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software R package to annotate cell types in scRNA-seq of tumour microenvironments.
Core collects data to capture and consider the real-time lived experiences of patients. Uses open-source digital platform and mobile app for neuropsychiatric research and clinical care, to monitor, support, and improve brain health by collecting real-time data (like location, activity, heart rate via sensors), conducting digital assessments (surveys, cognitive tests), and delivering interventions (meditation, journaling, psychoeducation) to patients and clinicians. It helps study behavioral patterns, track symptoms, and personalize mental health treatment through features organized around Learn, Assess, Manage, and Prevent.
Offers investigators clinical space, equipment, skilled nursing and nutrition services, project management and study coordinator support, resources for conducting community engagement research, as well as one-on-one consultation with Clinical/Translational Research Navigators.
Software tool which derives gene-specific probabilistic estimates of the strength of negative and positive selection in cancer.
Web application for identification of candidate synthetic lethal vulnerabilities in cancers.
IBIS Microscopy platform offers sample preparation and acces to TEM, SEM, STED, confocals and other microscopes.
Absorbance microplate reader offers all the functionality needed for photometric applications, including advanced 12-channel optics for fast, multichannel absorbance reading of ELISAs, temperature control function for enzyme kinetic assays, and tunable wavelength function for wavelength scanning.
REDCap (Research Electronic Data Capture) is a secure HIPAA compliant web-based data collection application hosted by Research and Academic Computing (ARC), a department of Beth Israel Deaconess Medical Center (BIDMC) which is itself part of Beth Israel Lahey Health (BILH). The function of the REDCap Core is to provide REDCap-related services and support to all BILH users.
Core is part of the Center for Innovative Biomedical Resources (CIBR) and is located on the 6th floor of Howard Hall. All services, instrumentation, and training courses are available to anyone, academic or private users, with an interest in electron microscopy.EMCIF services are managed by iLab core facility management program. New users must register in iLab to access instrument and EMCIF services.
Resource serves as a 'Digital Specimen' for Digital Organismal Biology, providing interactive Neuroglancer-based visualization and 3D segmentation masks for major organ systems, including the digestive, respiratory, vascular, and nervous systems. It specifically annotates novel neural tracts including the Intermediate Longitudinal Tracts (iLT) and Arm-to-Arm U-Tracts (AAUT) as well as ~300 additional tissue and organ level segmentations. Provides high-resolution (0.7 µm isotropic), whole-organism microCT reconstruction of an intact hatchling Octopus bimaculoides.
Source code for training and inference of InstaNovo and InstaNovo+. InstaNovo is a transformer neural network with the ability to translate fragment ion peaks into the sequence of amino acids that make up the studied peptide(s).
Benchtop automated Ella platform utilizes microfluidic Simple Plex assay cartridge designed to perform all reagent additions, wash steps, and incubations under precisely controlled conditions to run ELISA assays. Available for plexing up to 8 analytes.
Core Facility is a 3,000+ fish tank facility, located in the Slosberg-Landay building, equipped with 48 racks which hold standard sized adult zebrafish tanks, three-rack nursery space for larval fish, and quarantine space containing two stand-alone housing systems. Wild-type lines are maintained inhouse for shared use. Wet lab space is available for breeding and line maintenance; core staff and facility-associated technicians perform daily feeding. The core includes a dedicated procedure room for embryo manipulation.
Core offers services including statistical analyses, grant applications, prep for manuscript publications, etc.
Bruker ELEXSYS-E580 pulse X-/Q-band instrument offers state-of-the-art capabilities for both standard and cutting-edge EPR spectroscopy across a broad range of sample types and experimental needs. High-performance Electron Paramagnetic Resonance (EPR) spectrometer used for advanced research in chemistry, materials science, biochemistry, and physics, enabling studies of paramagnetic molecules, protein structures, quantum states, and materials by combining X-band (9-10 GHz) and Q-band (34 GHz) frequencies for high-resolution, sensitive pulse techniques.
Software package provides different SHapley Additive exPlanations (SHAP) algorithms for calculating SHAP values, including Kernel SHAP. Used for explaining predictions made by complex machine learning models.
Software 3D Slicer plugin for Liver Anatomy Annotation by R-Vessel-X.
Software R package for latent class analysis, short time Fourier transform, fuzzy clustering, support vector machines, shortest path computation, bagged clustering, naive Bayes classifier, generalized k-nearest neighbour.
Software tool for optimizing likelihood conditioning on high point estimate of local genetic correlation and assesses statistical evidence that the two traits not only exhibit correlated genetic effects but are likely influenced by shared causal variants.Enhances specificity and interpretability in detecting colocalized signals. This targeted framework improves causal inference in pleiotropic architectures, supporting more informed discovery of biomarkers and therapeutic targets.
Text-mined and routinely updated database of drivers, oncogenes and tumor suppressors in different types of cancer.