Curator Dashboard

Biomedical Technology Research Center to develop methods and analytical approaches to 3D microscopy. Applicable to neurobiology and cell biology, incorporating equipment and implementing software that expand the analysis of 3D structure.

• Organization
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

The University of California, San Diego is a public research university located in the La Jolla neighborhood of San Diego, California, in the United States. One of the leading public research universities in the world.

• Organization
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Software tool for automated analysis of 1-D electrophoretic gels, western blots, dot blots, slot blots, arrays, and colony counts.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Anita Bandrowski

Open resource for nonhuman primate imaging.Used for aggregation independently acquired non-human primate magnetic resonance imaging (MRI) datasets and openly sharing them via the International Neuroimaging Data-sharing Initiative (INDI).Consortium and data collection for the neuroimaging community to map the non-human primate connectome. Anatomical, functional, and diffusion MRI datasets openly shared via the International Neuroimaging Data sharing Initiative (INDI).

• Resource
• SciCrunch
• 7 years ago - submitted by Maryann Martone

CHAT is a multi-center randomized trial comparing early adenotonsillectomy to watchful waiting plus supportive care. It includes PSG recordings from 464 children aged 5-9.9 years with mild to moderate obstructive sleep apnea. The polysomnographic (PSG) montage includes the following signals: EEG, ECG, EOG, SaO2, EMG, plethysmography, airflow, nasal pressure, respiratory effort, position, capnography, snore.

• Resource
• RRID-Legacy
• 7 years ago - submitted by Sara Mariani

Collection of curated, non-redundant genomic DNA, transcript RNA, and protein sequences produced by NCBI. Provides a reference for genome annotation, gene identification and characterization, mutation and polymorphism analysis, expression studies, and comparative analyses. Accessed through the Nucleotide and Protein databases.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms.

• Resource
• SciCrunch
• 7 years ago - submitted by Edyta Vieth

Portal for analysis and interpretation of pediatric genomic and clinical data to advance personalized medicine for detection, therapy, and management of childhood cancer and structural birth defects. For patients, researchers, and clinicians to create centralized database of well curated clinical and genetic sequence data from patients with childhood cancer or structural birth defects.

• Resource
• SciCrunch
• 8 years ago - submitted by Anita Bandrowski

Phospho-MAPK14-T180/Y182 pAb

• Resource
• SciCrunch
• 8 years ago - submitted by Yan Qiu

A data-driven educational resource pertaining to opioid addiction and how it is likely to happen with prescription drugs. It also includes information pertaining to state-by-state legislation. Insufficient information. Waiting for PMID or manuscript info

• Resource
• D3R
• 8 years ago - by Anonymous

Project to collect and provide data on the human genome and epigenome to facilitate genetic studies of type 2 diabetes and its complications. Component of the Accelerating Medicines Partnership (AMP) T2D consortium, which includes the National Institute for Diabetes and Digestive and Kidney Diseases (NIDDK) and academic, industry and non-profit institutions worldwide.

• Resource
• dkNET
• 8 years ago - submitted by Ko-Wei Lin

Portal enables browsing, searching, and analysis of human genetic information linked to cerebrovascular disease and related traits, while protecting the integrity and confidentiality of the underlying data.

• Resource
• SciCrunch
• 8 years ago - submitted by Ko-Wei Lin

This is a zebrafish that knock out ponli by CRISPR/cas9.It lacks 4 amino acids.We use it to analyze its phenotype and study its internal pathological changes.

• Organization
• SciCrunch
• 8 years ago - submitted by 翁 科超

This is a fish that knock out crb2b by CRISPR/cas9.It lacks 5 amino acids.We use it to analyze its phenotype and study its internal pathological changes.

• Organization
• SciCrunch
• 8 years ago - submitted by 翁 科超

Recombinant mouse Osteolectin protein purified from supernatant of 293 cells overexpressing 3'Flag-tagged mouse Osteolectin (PMID: 27976999)

• Resource
• SciCrunch
• 8 years ago - submitted by Bo Shen

Recombinant human Osteolectin protein purified from supernatant of 293 cells overexpressing 3'Flag-tagged human Osteolectin (PMID: 27976999)

• Resource
• SciCrunch
• 8 years ago - submitted by Bo Shen

Ay and other mutations at the a locus conferring a completely yellow coat color are dominant to all a alleles that produce a darker coat. Hair pigment of Ay heterozygotes is yellow, but eyes are black. Heterozygotes usually become obese and infertile within a few months after birth. Increased adipose tissue mass is due to fat cell hypertrophy, and it has been hypothesized that the obesity results from the observed reduction in hypothalamic norepinephrine and dopamine. Heterozygotes are more susceptible to several kinds of tumors than are normal mice, possibly due, at least in part, to a general increase in cell proliferation that also manifests as a slight increase in lean body mass and skeletal length. Further spleen cells from heterozygotes cause a significantly lower graft vs. host reaction. Mice homozygous for the yellow spontaneous mutation (Ay) die before implantation, or shortly thereafter. The time of death and type of abnormality is, in part, determined by the genetic background on which the mutation is placed. Mice of the KK strain develop diabetes of polygenic origin, and mice of other strains heterozygous for Ay become obese and mildly diabetic. KK.Cg-Ay/J heterozygotes develop hyperglycemia, hyperinsulinemia, glucose intolerance and obesity by eight weeks of age. Studies using isolated adipocytes indicate that tissue responsiveness to insulin is decreased. Histo- and immunocytochemical studies show that the pancreatic islets are hypertrophied and the β-cells are degranulated. These findings suggest that the principal cause of diabetes in these mice is insulin resistance. Body composition analysis shows that both the fat and lean tissue mass are increased compared to non-obese mice, with fat accounting for 30-35% of total body weight. The pleiotropic mutant phenotype of Ay/a mice is attributed to ectopic expression of the agouti protein, while the early embryonic lethality of the Ay mutation in the homozygous state is assumed to result from lack of expression of the Raly gene product (Bultman et al. 1992, Miller et al. 1993, Duhl et al. 1994, Michaud et al. 1993, 1994). That ectopic expression of the agouti protein is probably responsible for the non-lethal aspects of this mutation has been demonstrated by transgenic expression of the protein from a ubiquitous promoter (Klebig et al. 1995, Perry et al. 1995).

• Resource
• RRID-Legacy
• 8 years ago - submitted by Thai Tran

The GeneChip Scanner 3000 7G is an extension of the GeneChip Scanner 3000 (GCS 3000) series that allows you to scan next-generation higher-density arrays, including SNP arrays with up to 900,000 SNPs, tiling arrays for transcription and all-exon arrays for whole-genome analysis. The GCS 3000 7G combines space-saving and other design improvements with speed, superior performance and lower scanner-to-scanner variation to dramatically improve throughput and efficiency in your genetic analysis. The GCS 3000 7G also provides enhanced auto-focus and more consistent scanner-to-scanner biological performance to improve data integrity and data sharing between researchers. In addition the GCS 3000 7G has been designed to accommodate future advancements in GeneChip probe array technology. Combined with the GeneChip AutoLoader, the GCS 3000 7G provides sample tracking, temperature control and walk-away freedom from scanning. This scanner is sold with a powerful computer workstation with quad-core Xeon processor loaded with Affymetrix GeneChip Command Console Software (AGCC).

• Resource
• RRID-Legacy
• 8 years ago - submitted by Thai Tran

GeneChip™ WT Sense Target Labeling and Control Reagents (900652) and GeneChip WT cDNA Synthesis and Amplification Kits (900672 and 900673) are being discontinued in June 2010. The Whole Transcript (WT) Sense Target Labeling Assay has an updated protocol. The GeneChip WT (Whole Transcript) Terminal Labeling Kit is optimized to be used for the fragmentation and labeling steps of the GeneChip WT Sense Target (ST) Labeling Assay. The WT Terminal Labeling Kit employs a strategy for reproducible DNA fragmentation with a combination of uracil DNA glycosylase (UDG) and apurinic/apyrimidinic endonuclease 1 (APE 1). The typical input material is random-primed, single-stranded DNA Following fragmentation, the resulting fragmented DNA can then be labeled using terminal deoxynucleotidyl transferase (TdT) in the presence of a proprietary biotinylated compound, GeneChip DNA Labeling Reagent. Both components are also provided in the WT Terminal Labeling Kit. The final labeled DNA target is ready to be added to the cocktail for hybridizing to the arrays such as the GeneChip Human Exon 1.0 ST Array.

• Resource
• RRID-Legacy
• 8 years ago - submitted by Thai Tran

The RNeasy Mini Kit provides fast purification of high-quality RNA from cells, tissues, and yeast using silica-membrane RNeasy spin columns with a binding capacity of 100 μg RNA. Tissue samples can be conveniently stabilized using RNAlater RNA Stabilization Reagent or Allprotect Tissue Reagent, and efficiently disrupted using a TissueRuptor or TissueLyser system. RNA purification using the RNeasy Mini Kit can be fully automated on the QIAcube. For smaller and larger samples, the RNeasy Micro Kit (spin-column binding capacity of up to 45 µg RNA), the RNeasy Midi Kit (spin-column binding capacity of 1 mg RNA), and RNeasy Maxi Kit (spin-column binding capacity of 6 mg RNA) are also available.

• Resource
• RRID-Legacy
• 8 years ago - submitted by Thai Tran