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Software command-line tool designed to simulate circular DNA and RNA sequences and generate corresponding sequencing reads. This tool can be helpful for researchers working with circular DNA (like eccDNA) or RNA, providing an easy way to simulate the coordinates of these molecules and generate sequencing files for further analysis.
Web application to explore somatic mutations in large breast cancer RNA-sequencing datasets, particularly from the Sweden Cancerome Analysis Network–Breast (SCAN-B) project, helping to link genetic alterations to clinical features, patient outcomes (like survival), and potential drug targets, adding a dimension to gene expression analysis for guiding treatment.
Electron microscopy core provides microscopy and image analysis, applications development, and services.
Interactive database and user interface providing online access to validated alternative methods for U.S. regulatory and other contexts of use. Central hub and unified resource of validated alternative methods that enhances accessibility to validation study reports, data, protocols / SOPs, and information on regulatory guidance.Users can filter searches by alternative method types, defined approaches, Test Method Endpoint, and regulatory guidance.
Software package for quantifying transposable elements at a locus level for RNAseq datasets. TElocal base algortihm is derived from the published TEtranscripts tool.
As part of the cellular engineering and vectorology core facility (ICV), the iPSC core facility (ICV-iPS) proposes the generation and the genetic engineering of human induced pluripotent stem cells to internal research teams, external academic teams, and industrial partners. Services include generation of human iPSc with Sendai virus, full molecular and functional characterization of iPSc clones, genetic engineering of human iPSc with CRISPR/Cas9 system and theoretical and practical learning sessions on human iPSc culture. The core facility provides also access to L2 cell culture box dedicated to human iPSc culture.
Software application for fast phylogenetic maximum parsimony tree inference and bootstrap approximation.
Web application for facilitating compliance with the minimal data standards (MDS) set by the open data commons for SCI and TBI.
Specialized monitor engineered for scientific rigor, replacing consumer displays with research-grade control and synchronization for visual experiments. Features high-performance industrial LCD glass, and a panel controller which has been custom designed to support vision research. Includes an array of peripherals which often need to be synchronized to video during an experiment, including stereo audio stimulator, button box port for precise reaction-time measurement, triggers for electrophysiology equipment, and complete analog I/O subsystem.
Portal that allows users to explore taxonomy-guided genome selections, visualize epigenetic assays, and analyze chromatin data across basal ganglia cell populations identified by the BRAIN Initiative Cell Atlas Network (BICAN) with an interactive research platform. The portal allows for investigation of several key epigenetic assays including associated with active enhancers and promoters, repressed genes, and constitutive heterochromatin. Used to analyze complex genomic and epigenomic data from the brain, helping identify specific cell types, understand gene regulation, and map disease-related molecular events, ultimately aiding in understanding neurological disorders like Alzheimer's, autism, and depression by revealing what goes wrong at the cellular level, leading to better gene therapies.
"A unique powdered blend of researched prebiotic fibers and polyphenols to support gastrointestinal, cellular, and immune function by boosting bifidobacteria and microbiome diversity‡"
Collection of molecular genetic reagents to gain access to many different brain cell types. Provides scientists with advanced genetic tools, primarily AAV (Adeno-Associated Virus) vectors with cell-type specific "enhancers," to precisely target, map, monitor, and manipulate specific cell types and circuits in the brain and spinal cord.
Database of complete listing of data sets generated by the Brain Initiative Cell Atlas Network (BICAN). Used to find, access, and use data from the BRAIN Initiative's efforts to map brain cell types, integrating molecular, anatomical, and functional data from mouse, primate, and human brains. Its purpose is to provide a comprehensive, open-access "parts list" of the brain, accelerate neuroscience discovery, and help understand brain disorders by offering links to raw data, visualizations, and tools for a vast array of cell types and circuits.
Software tool to decipher patterns of communication. Used to relay-network communication detection that identifies putative ligand–receptor–ligand–receptor communication. Detects T cell homing signals in human lymph nodes, identifies aggressive cancer communication in lung adenocarcinoma and colorectal cancer, and predicts new patterns of communication that may act as relay networks in pancreatic cancer.
Software R package to infer genome-wide copy-number variations (CNVs) from spatially resolved in situ mRNA profiles. SpatialInferCNV will generate CNV calls in each spatial region represented by barcoded spots.
Core provides services in mass spectrometry including protein identification and analysis, measuring the intact mass of proteins and quantitative proteomics.
V-Dem Institute is an independent research institute that serves as the headquarters of the V-Dem Project a database that seeks to conceptualize and measure democracy. Provides interactive map for comprehensive overview of academic freedom in 179 countries and territories in 2024. Based on assessment of the de facto protection of academic freedom as of December 2024, users can compare countries and investigate developments within countries over time.
Cloud-based data science platform for flow cytometry and single-cell analysis, streamlining complex workflows from raw data to insights, enabling collaboration, and ensuring reproducibility with automated tasks, machine learning, and integration for classical and high-dimensional cytometry data. Modern Cloud Software for classical and advanced Flow Cytometry analysis.
Software versatile all-purpose image and graphics editor for Windows, macOS, and Linux (via Wine) that combines raster (bitmap) and vector editing, making it a strong, affordable alternative to Adobe Photoshop, with features like layers, masks, color management (CMYK, Lab, 16-bit), batch processing, and web tools, presented in a comprehensive yet sometimes retro-looking interface . You can edit images or optimize them for the web, but you can also prepare print-ready PDF data.
Provides online, collaborative working space and data-sharing platform. Provides services with data management planning, boilerplate text for proposal, sample plans and individual consultation. Each dataset gets DOI. PURR publishes and archives digital datasets from researchers across campus and welcomes all kinds of open data from images and videos to spreadsheets and source code.