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Four datasets cover two types of cell structures, tubulin filaments and vesicle structures. These datasets are structured so that the research community can easily use them for research on different image restoration tasks. The link provided contains the comprehensive details of the datasets.
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Core offers services in advancing scientific research in the field of chemistry. Provides Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), Confocal Laser Scanning Microscopy (CLSM), and Optical Microscopy. Offers sample preparation techniques, including ultramicrotome, ultracryomicrotome, and sputter coating,training and technical support.
Medical Genome Facility includes Cytogenetics Core, Genome Analysis Core and Proteomics Core. Available services include Sanger DNA sequencing, genotyping, gene expression and cytogenetic analysis, biospecimens accessioning and processing, tissue and cell molecular analysis, RNA interference, and oligonucleotide synthesis. Provides Illumina HiSeq2000 platforms and Pacific Biosciences RS single molecule real-time sequencer.Offers applied research services for development of innovative, personalized tests and treatments, especially with regard to biomarkers.
Core provides analytical flow cytometry services and live cell sorting under enhanced Biosafety Level 2 conditions. Instruments available include six analyzers ranging from 4-30 color acquisition and three sorters using 1-,2-,4-way, and plate sorting between 6-18 colors. Provides experimental and panel design consultation. Provides continued education in seminar format and one-on-one sessions with user.
Core provides research support and training with molecular pathology skills, confocal microscopy, image analysis, and multicolor immunohistochemistry and in-situ hybridization techniques for internal and affiliate scientists. Services include assistance with experimental design, antibody selection, molecular probe selection, fixation and staining protocols, operating fluorescent and confocal microscopes, acquiring and storing imaging data, interpretation of results, and generation of publication-quality images. Image analysis services include assistance with capturing images for evaluation and with use of various image analysis software.
Provides full or partial support for researchers seeking to perform BSL3 and BSL2/BSL3 Select Agent studies and provides services for bacterial/viral culture and propagation, sample preparation, and processing of blood, BAL, single cell isolation, flow cytometry, and more. Offers project management assistance in study design, budgeting, and IACUC and IBC preparation. Our standard operating procedures have been tested to ensure consistent practices and have undergone rigorous quality assurance processes to ensure reproducibility. Offers assay services for qPCR, O�link Q100, Biorad Bioplex 200, Meso QuickPlex SQ120 Imager and Microscope Axio Observer.
Core serves as regional and national resource and center of excellence for biomedical research using Nonhuman Primate Models. Unit is staffed by personnel with expertise in veterinary medicine, research study design, budgeting, database management, IACUC issues, sample acquisition, processing, performing laboratory base assays and shipping.
Core assists in design of breeding groups and monitors genetic diversity among colony�s breeding animals. Core is responsible for maintaining genome bank including DNA and cryopreserved primary fibroblast cell lines, including cell lines and DNA samples representing nearly 9,000 animals. Genotype data using NPRC standardized SNP array is available and whole genome sequence is available for over 520 animals. Genomic data is available via mGAP and can be integrated with physical resource and records by contacting the core. Targeted genotyping for new model development and specialized breeding is also available.
Clinical Pathology Core performs clinical diagnostic testing for all research and colony animals. This includes complete blood counts, routine chemistry panels, and microbial culture workups. The lab is equipped with Sysmex XN1000v veterinary hematology analyzer, Beckman AU480 chemistry analyzer, and Matrix assisted laser desorption ionization time of flight MALDI-TOF instrument for microbe identification. CPC is staff with American Society of Clinical Pathologist certified licensed Medical Technologists.
Core focuses on infectious disease aerobiology. Core facilitates biomedical research efforts that require unique demands of aerosol and aerobiology in their respective performance.
Core provides services for maintaining Specific Pathogen Free status in macaque breeding colonies. Services include antibody detection in serum or plasma by Luminex-based assays and /or ELISA for SPF-agents like SIV, SRV, STLV, B virus, SFV. CMV, RRV, SVV, SV40, and LCV, and non-SPF infectious agents like measles, Burkholderia pseudomallei, Tripanosoma cruzi, Mycobacterium tuberculosis, and SARS-CoV-2. Offers services of cytokines quantification, and molecular assays for detection of SRV, CMV, SFV, and RRV.Performs nucleic acid purification from blood and tissue samples as well as qPRC for SIV viral load in plasma, cells, or tissue.
Immunology Assay Core provides several immunology services to core and affiliate investigators. Offers multicolor staining for flow cytometry, access to inventory of commonly used antibodies, reagent compounding, sample processing such as cell isolation, automated cell separation through RoboSep, and irradiation of biological samples.Offers multiplex assays using MESO QuickPlex SQ 120 Imager to investigators.
Anatomic Pathology Core is responsible for post-mortem examinations, tissue collection and distribution, fixation, processing, slide preparation, routine and special staining, and diagnostic gross and histologic pathology services. Processes and interprets biopsy specimens for both research and diagnostic purposes and provides tissue trimming, paraffin processing, sectioning, and routine and special staining for clinical and research staff and faculty. APC works closely with clinical veterinarians, and through diagnostic pathology on biopsies and necropsies, plays major role in monitoring and maintaining health of animals in breeding colonies.
Software toolkit to check reliability and to make some analysis of data from Live Mouse Tracker experiments. LMT stores data in SQLite files but LMT-toolkit makes it easy to compute and extract behavioral profiles for each animal tested.
With Stereo Investigator, you can perform unbiased quantification of cell populations, lengths of fibers or vessels, or area and volume of regions using design-based stereology, a set of methods for rigorous quantitative analysis of the size, shape, and number of objects. Stereo Investigator leverages unbiased statistical sampling, that helps enable researchers to count, measure, and precisely quantify visible features in microscope specimens without needing to examine the entire specimen to obtain statistically valid results.
Data platform for academic research. Redivis provides organizations with central hub where researchers can easily discover, access, and analyze their data.
Xenopus laevis defolliculated oocytes ready to use for mRNA or cDNA injections for expression studies.
Our primary goal is to identify and quantify the small (