Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=8586
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: |sphingosine kinase 2|sphingosine kinase 1
Genomic Alteration: transgene insertion 1; University of Cologne|targeted mutation 1; Richard L Proia|targeted mutation 2; Shaun R Coughlin
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: |sphingosine kinase 2|sphingosine kinase 1; mutant strain: |Sphk2|Sphk1
Proper citation: RRID:IMSR_APB:8586 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=8631
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: apolipoprotein E|toll-like receptor 9
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Shizuo Akira
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: apolipoprotein E|toll-like receptor 9; mutant strain: Apoe|Tlr9
Proper citation: RRID:IMSR_APB:8631 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=1510
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: |interferon gamma
Genomic Alteration: transgene insertion 1100; Michael J Bevan|targeted mutation 1; Timothy Stewart
Availability: sperm
References:
Synonyms: B6.Cg-Infng
Notes: gene symbol note: |interferon gamma; mutant strain: |Ifng
Proper citation: RRID:IMSR_APB:1510 Copy
Issue Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=2396
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor receptor superfamily; member 1a
Genomic Alteration: targeted mutation 1; Immunex Research and Development Corporation
Availability: sperm
References:
Synonyms: B6.129S-Tnfrsf1b
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor receptor superfamily; member 1a; mutant strain: Tnfrsf1b|Tnfrsf1a
Proper citation: RRID:IMSR_APB:2396 Copy
Issue Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=2395
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor|tumor necrosis factor receptor superfamily; member 1a
Genomic Alteration: targeted mutation 1; Immunex Research and Development Corporation|targeted mutation 2; Jonathon D Sedgwick
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor|tumor necrosis factor receptor superfamily; member 1a; mutant strain: Tnfrsf1b|Tnf|Tnfrsf1a
Proper citation: RRID:IMSR_APB:2395 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=4702
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: Fas cell surface death receptor; mutant strain|congenic strain: Fas
Proper citation: RRID:IMSR_APB:4702 Copy
Issue Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=5238
Source Database: Australian Phenome Bank
Genetic Background:
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: sperm
References:
Synonyms: B6.129S2-Il6
Notes: gene symbol note: interleukin 6; mutant strain: Il6
Proper citation: RRID:IMSR_APB:5238 Copy
Issue
https://brc.riken.jp/mus/RBRC04495
Source Database: RIKEN BioResource Research Center
Genetic Background:
Affected Genes: transgene insertion 1; Masashi Yanagisawa|TEK receptor tyrosine kinase|
Genomic Alteration: transgene insertion 1; Masashi Yanagisawa|endothelial-specific receptor tyrosine kinase|
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: transgene insertion 1; Masashi Yanagisawa|TEK receptor tyrosine kinase|; mutant stock: Tg(Tek-cre)1Ywa|Tek|
Proper citation: RRID:IMSR_RBRC04495 Copy
Issue Issue
https://brc.riken.jp/mus/RBRC05131
Source Database: RIKEN BioResource Research Center
Genetic Background:
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: interleukin 6; mutant stock: Il6
Proper citation: RRID:IMSR_RBRC05131 Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Genetic Background:
Affected Genes: toll-like receptor 9|toll-like receptor 2|toll-like receptor 4
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
References:
Synonyms: TLR2/4/9 Triple KO C57BL/6. B6.129P2-Tlr2
Notes: gene symbol note: toll-like receptor 9|toll-like receptor 2|toll-like receptor 4; mutant strain|congenic strain: Tlr9|Tlr2|Tlr4
Proper citation: RRID:IMSR_OBS:21 Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Genetic Background:
Affected Genes: toll-like receptor 4|toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
References:
Synonyms: B6.129P2-Tlr2
Notes: gene symbol note: toll-like receptor 4|toll-like receptor 2; mutant strain|congenic strain: Tlr4|Tlr2
Proper citation: RRID:IMSR_OBS:19 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: immunoglobulin heavy constant mu
Genomic Alteration: targeted mutation 1; University of Cologne
Availability: embryo
References:
Synonyms: muMT<0>(muKO)
Notes: gene symbol note: immunoglobulin heavy constant mu; mutant strain: Ighm
Proper citation: RRID:IMSR_EM:00001 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=29
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: archived
References:
Synonyms: beta2m<0>
Notes: gene symbol note: beta-2 microglobulin; mutant strain: B2m
Proper citation: RRID:IMSR_EM:00029 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abb-knockouttransgenic-hla-dr4
Source Database: Taconic Biosciences
Genetic Background:
Affected Genes: histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Michael J Grusby
Availability: live
References:
Synonyms:
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: H2-Ab1
Proper citation: RRID:IMSR_TAC:4149 Copy
Issue
https://www.taconic.com/transgenic-mouse-model/apoe
Source Database: Taconic Biosciences
Genetic Background:
Affected Genes: |apolipoprotein E
Genomic Alteration: |targeted mutation 1; University of North Carolina
Availability: live
References:
Synonyms: Apoe (ApoE) CONSTITUTIVE KNOCK OUT - C57BL/6 Background. B6.129P2-Apoe
Notes: gene symbol note: |apolipoprotein E; mutant strain|congenic strain: |Apoe
Proper citation: RRID:IMSR_TAC:APOE Copy
Issue
https://www.taconic.com/transgenic-mouse-model/hla-b7
Source Database: Taconic Biosciences
Genetic Background:
Affected Genes: beta-2 microglobulin|
Genomic Alteration: targeted mutation 1; University of North Carolina|transgene insertion 55; Hidde Ploegh
Availability: live
References:
Synonyms:
Notes: gene symbol note: beta-2 microglobulin|; unclassified|mutant stock: B2m|
Proper citation: RRID:IMSR_TAC:9661 Copy
Issue
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=32236
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Targeted Mutation
Affected Genes: Csmd1
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Research areas: Cancer, Developmental Biology, Immunology and Inflammation, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Proper citation: RRID:MMRRC_032236-UCD Copy
Issue
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36310
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Targeted Mutation
Affected Genes: Atp8b1
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Research areas: Cell Biology, Internal/Organ, Metabolism, Models for Human Disease, Sensorineural; Mutation Type: Targeted Mutation ; Collection:
Proper citation: RRID:MMRRC_036310-UCD Copy
Issue
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36309
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Targeted Mutation
Affected Genes: Atp8b1
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Research areas: Cell Biology, Internal/Organ, Metabolism, Models for Human Disease, Sensorineural; Mutation Type: Targeted Mutation ; Collection:
Proper citation: RRID:MMRRC_036309-UCD Copy
Issue
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37140
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Targeted Mutation
Affected Genes: Ifng
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen
Proper citation: RRID:MMRRC_037140-MU Copy
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