Searching the RRID Resource Information Network
Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: ∆HHT2/HHF2;.∆HHT1;∆HHF1 homozygous heterkaryon (pm-r)
Affected Genes: HHT1 (TTHERM_00570560),HHT2 (TTHERM_00189180), HHF1 (TTHERM_00498190), HHF2 (TTHERM_00189170)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: These are intermediate germlineKO heterokaryons not thoroughly tested for somatic rescue. Final KO strains are #4 and#7. This is the star side.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02005 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hht1[∆::neo2]/hht1[∆::neo2];hht3[∆::neo2]/hht3[∆::neo2]; hht2[3’neo2,S10E]/ hht2[3’neo2,S10E]; mpr1-1/mpr1-1 (hht1[∆::neo2]]; hht3[∆::neo2]; hht2[3’neo2,S10E]; pm-r, mp-r, ?)
Affected Genes: HHT1 (TTHERM_00570560) + HHT2 (TTHERM_00189180)
Genomic Alteration: Micronucleus: Neo KO of HHT1.HHT3, HHT2 has S10E mutaion and neo2 in 3’ flanking region Macronucleus: Neo KO of HHT1.HHT3, HHT2 has S10E mutaion and neo2 in 3’ flanking region
Availability:
References:
Synonyms:
Notes: H3 with S10E mutation in a background with no wildtype H3 present.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02527 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpr1-1/mpr1-1 (MPR1; cy-s, mp-s, tr, IV)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD00071 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: (pdd2[∆?::neo2], ?)
Affected Genes: PDD2 (TTHERM_00283530)
Genomic Alteration: Macronucleus: PDD2 with neo2 replacing the 5’ part of coding
Availability:
References:
Synonyms:
Notes: Progeny of B2086XCU428 transformation. Somatic KO of PDD2 gene.
Mates with CU427, CU428, ∆PDD2-som-BC4, BC5
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD01322 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; MPR1[C3]/MPR1[C3]; pmr1-1/pmr1-1; MAT2/MAT2 (chx1-1;MPR1[C3]; pmr1-1; MAT2; cy-r, mp-s, pm-r, V)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Submitted by Eduardo Orias, University of California, Santa Barbara
Proper citation: RRID:TSC_SD01288 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: BLT1/ blt1-1[∆,neo3]; MPR1-?/ MPR1-? (BLT1; mpr1-1; mp-r, ?)
Affected Genes: BLT1 (TTHERM_01104960)
Genomic Alteration: Micronucleus: Neo3 replaces BLT coding
Availability:
References:
Synonyms:
Notes: BLT germline heterokaryon, heterozygous KO in mic, pm sensitive (120 ug/ml). Cd induced Neo cassette (1.2 ug/ml)--MTT promoter, Neo coding, BTU2 terminator. Construct pBLTMKO,
From the Gorovsky lab, University of Rochester.
Proper citation: RRID:TSC_SD02259 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; pmr1-1/pmr1-1; Del 2L (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Deletion on left arm of chromosome 2.
Proper citation: RRID:TSC_SD00874 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: ubc2[∆::neo2]/ubc2[∆::neo2] (?)
Affected Genes: UBC2 (TTHERM_00550720)
Genomic Alteration: Micronucleus: Neo2 KO of UBC2
Availability:
References:
Synonyms:
Notes: UBC2 KO homozygous heterokaryon. Mates with ∆UBC2gl 1B2.8 and 1B2.10
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02537 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: ubc2[∆::neo2]/ubc2[∆::neo2]
Affected Genes: UBC2, RAD6 (TTHERM_00550720)
Genomic Alteration: Micronucleus: Neo2 KO of UBC2
Availability:
References:
Synonyms:
Notes: UBC2 KO homozygous heterokaryon. Mates with ∆UBC2gl 1D1.4, 1D1.8 and 2B1.2.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD01329 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]/ btu1-? [E437D,E438D,E439D,E440D,E442D]; ATU1/atu1-1[α-β hybrid tail, ATU-B]; pm-r, Original BTU2 is replaced by bsr1, BTU1 coding replaced by neo1, then transformed with pBTU1-D5 (D-DDDD) and Chimeric ATU1 gene, ATU-B (α-β hybrid ))
Affected Genes: BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580), ATU1 (TTHERM_00558620)
Genomic Alteration: Micronucleus: knockout of btu1 with neo
knockout of btu2 with bsr Macronucleus: BTU2 replaced by bsr. BTU1 partially replaced by neo1, some replaced by BTU1-D5 with (E437-442D). Some ATU1 replaced by ATU1 with chimeric α-β hybrid tail.
Availability:
References:
Synonyms:
Notes: Progeny of DB6B x DB2A, co- transformed by constructs pBTU1-D5 (D-DDDD) and Chimeric ATU1 gene, pATU-B (α-β hybrid). See publications
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD01848 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Submitted by P. Huvos, Southern Illinois Univesity
Proper citation: RRID:TSC_SD01735 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/Chx1-1[C3]; MAT2/MAT3 (chx1-1; MAT2; cy-r, VII)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Not useful for mapping loci on MIC chromosome 3R. One parent was missing this chromosome arm, so the progeny were not heterozygous.
Submitted by Eduardo Orias, University of California, Santa Barbara
Proper citation: RRID:TSC_SD01979 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; pmr1-1/pmr1-1; Del 2R (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Deletion on right arm of chromosome 2.
Proper citation: RRID:TSC_SD00923 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2] (htax[∆::neo2]/htax[K123R]; hta1[∆::neo2]; mp-r, ?)
Affected Genes: HTA1 (TTHERM_00790790)
Genomic Alteration: Micronucleus: Neo2 KO of HTAX and HTA1 Macronucleus: Neo2 KO of HTA1, partial KO of HTAX some HTAX has K123R mutation
Availability:
References:
Synonyms:
Notes: New batch, rescue of h∆∆HTA-A1F14A1 and B1G6A. Not mating type II, VI, or VII.
This strain was marked as pm-r, but no longer is.
From the Gorovsky lab, University of Rochester.
Proper citation: RRID:TSC_SD02399 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: dbl1-1/dbl1-1 (dbl1-1, II)
Affected Genes: DBL1 (doublet-former 1)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: A variable proclivity to form regular homopolar doublets. Enigmatic. Derivation highly complex, crosses of presumed homozygotes are inviable. Highly variable penetrance of doublets. It is not known how the doublets are actually formed.
Submitted by Joseph Frankel, University of Iowa
Proper citation: RRID:TSC_SD01464 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: Uni 1 [chx1-1/chx1-1[B] or CHX1/CHX1[C3]] (cnj3, pm-r, VII)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes:
Proper citation: RRID:TSC_SD00378 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E445A,E446A]; pm-r, mp-?, ?)
Affected Genes: ATU1 (TTHERM_00558620)
Genomic Alteration: Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E445A, E446A and neo replacing coding of some ATU1 genes
Availability:
References:
Synonyms:
Notes: It is a progeny of conjugants of AAK02.7XAAKO5.5 transformed with pA5A6 derived from pTUB100E3-PvuII (linearized)where the ATU1 gene is marked with Hae III and Pvu II sites and E445A,E446A. No polyglycylation in this strain
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02558 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: gal1-1/gal1-1; tyrA5/tyrA5 (gal1-1; tyrA5; gal-r; tyr auxotroph, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Submitted by Eduardo Orias, University of California, Santa Barbara
Proper citation: RRID:TSC_SD01502 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; hhf1[∆::neo]/hhf1[∆::neo] (mpr1-1; mp-r, ?)
Affected Genes: HHT1 (TTHERM_00570560),HHT2 (TTHERM_00189180), HHF1 (TTHERM_00498190), HHF2 (TTHERM_00189170)
Genomic Alteration: Micronucleus: Neo into HHT1, HHF1, HHT2/HHF2
Availability:
References:
Synonyms:
Notes: These are intermediate germline KO heterokaryons. May be early batch and not tested for somatic rescue. Final germline KO strains are #4 and #7. Non-star side.
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02039 Copy
https://sites.wustl.edu/tetrahymena/finding-strains/
Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1 (rnh2[∆::neo3]; pm-r, VI)
Affected Genes: RNH2 (TTHERM_00142290)
Genomic Alteration: Macronucleus: neo3 KO of RNH2
Availability:
References:
Synonyms:
Notes: Somatic KO of RNH2 (RNase H-2) of CU427
From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.
Proper citation: RRID:TSC_SD02831 Copy
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