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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
STAR
 
Resource Report
Resource Website
10000+ mentions
STAR (RRID:SCR_004463) data processing software, alignment software, software application, software resource, image analysis software Software performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays. RNA-seq data, alignment, RNA-seq reads alignment, reference genome, using uncompressed suffix arrays, bio.tools is used by: STARsolo
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
NHGRI U54 HG004557 PMID:23104886
DOI:10.1093/bioinformatics/bts635
biotools:star, OMICS_01254, SCR_015899 https://github.com/alexdobin/STAR
https://bio.tools/star
https://sources.debian.org/src/rna-star/
SCR_004463 Spliced Transcripts Alignment to Reference, Spliced Transcripts Alignment to a Reference (STAR), rna-star, ultrafast universal RNA-seq aligner 2026-02-14 02:00:44 22809
NCBI BioSystems Database
 
Resource Report
Resource Website
100+ mentions
NCBI BioSystems Database (RRID:SCR_004690) BioSystems data repository, storage service resource, data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Database that provides access to biological systems and their component genes, proteins, and small molecules, as well as literature describing those biosystems and other related data throughout Entrez. A biosystem, or biological system, is a group of molecules that interact directly or indirectly, where the grouping is relevant to the characterization of living matter. BioSystem records list and categorize components, such as the genes, proteins, and small molecules involved in a biological system. The companion FLink tool, in turn, allows you to input a list of proteins, genes, or small molecules and retrieve a ranked list of biosystems. A number of databases provide diagrams showing the components and products of biological pathways along with corresponding annotations and links to literature. This database was developed as a complementary project to (1) serve as a centralized repository of data; (2) connect the biosystem records with associated literature, molecular, and chemical data throughout the Entrez system; and (3) facilitate computation on biosystems data. The NCBI BioSystems Database currently contains records from several source databases: KEGG, BioCyc (including its Tier 1 EcoCyc and MetaCyc databases, and its Tier 2 databases), Reactome, the National Cancer Institute's Pathway Interaction Database, WikiPathways, and Gene Ontology (GO). It includes several types of records such as pathways, structural complexes, and functional sets, and is desiged to accomodate other record types, such as diseases, as data become available. Through these collaborations, the BioSystems database facilitates access to, and provides the ability to compute on, a wide range of biosystems data. If you are interested in depositing data into the BioSystems database, please contact them. pathway, disease, gene, protein, small molecule, literature, computation, image, biomarker, drug, structural complex, functional set, biological system, molecule, gold standard, bio.tools is listed by: re3data.org
is listed by: Debian
is listed by: bio.tools
is related to: KEGG
is related to: NCBI Structure
is related to: BioCyc
is related to: EcoCyc
is related to: MetaCyc
is related to: Reactome
is related to: Pathway Interaction Database
is related to: WikiPathways
is related to: Gene Ontology
has parent organization: NCBI
NIH PMID:19854944 r3d100011033, biotools:biosystems, nlx_69646 https://bio.tools/biosystems
https://doi.org/10.17616/R31K80
SCR_004690 BioSystems Database, NCBI BioSystems 2026-02-14 02:00:59 118
QuickGO
 
Resource Report
Resource Website
500+ mentions
QuickGO (RRID:SCR_004608) QuickGO ontology, web service, data or information resource, controlled vocabulary, data access protocol, software resource, database A web-based browser for Gene Ontology terms and annotations, which is provided by the UniProtKB-GOA group at the EBI. It is able to offer a range of facilities including bulk downloads of GO annotation data which can be extensively filtered by a range of different parameters and GO slim set generation. The software for QuickGO is freely available under the Apache 2 license. QuickGO can supply GO term information and GO annotation data via REST web services. gene, ontology, annotation, browser, visualization, search engine, slimmer-type tool, ontology or annotation browser, ontology or annotation search engine, ontology or annotation visualization, database or data warehouse, windows, mac os x, linux, unix, gold standard, bio.tools is listed by: OMICtools
is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: STRAP
has parent organization: European Bioinformatics Institute
BBSRC BB/E023541/1 PMID:19744993
PMID:20157483
Apache License, v2, Free for academic use biotools:quickgo, nlx_60318, OMICS_02276 https://bio.tools/quickgo SCR_004608 Quick GO 2026-02-14 02:00:45 523
BioPig
 
Resource Report
Resource Website
1+ mentions
BioPig (RRID:SCR_004636) BioPig software resource Software providing a framework for genomic data analysis using Apache Pig and Hadoop. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
PMID:24021384 biotools:biopig, OMICS_01225 https://bio.tools/biopig SCR_004636 2026-02-14 02:00:58 2
Small Molecule Pathway Database
 
Resource Report
Resource Website
50+ mentions
Small Molecule Pathway Database (RRID:SCR_004844) SMPDB data analysis service, analysis service resource, data or information resource, production service resource, service resource, image, database An interactive, visual database containing more than 350 small molecule pathways found in humans. More than 2/3 of these pathways (>280) are not found in any other pathway database. SMPDB is designed specifically to support pathway elucidation and pathway discovery in metabolomics, transcriptomics, proteomics and systems biology. It is able to do so, in part, by providing exquisitely detailed, fully searchable, hyperlinked diagrams of human metabolic pathways, metabolic disease pathways, metabolite signaling pathways and drug-action pathways. All SMPDB pathways include information on the relevant organs, subcellular compartments, protein cofactors, protein locations, metabolite locations, chemical structures and protein quaternary structures. Each small molecule is hyperlinked to detailed descriptions contained in the HMDB or DrugBank and each protein or enzyme complex is hyperlinked to UniProt. All SMPDB pathways are accompanied with detailed descriptions and references, providing an overview of the pathway, condition or processes depicted in each diagram. The database is easily browsed and supports full text, sequence and chemical structure searching. Users may query SMPDB with lists of metabolite names, drug names, genes / protein names, SwissProt IDs, GenBank IDs, Affymetrix IDs or Agilent microarray IDs. These queries will produce lists of matching pathways and highlight the matching molecules on each of the pathway diagrams. Gene, metabolite and protein concentration data can also be visualized through SMPDB''s mapping interface. All of SMPDB''s images, image maps, descriptions and tables are downloadable. metabolomics, transcriptomics, proteomics, systems biology, small molecule, pathway, human, metabolic pathway, metabolic disease pathway, metabolite signaling pathway, drug-action pathway, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: ConsensusPathDB
has parent organization: University of Alberta; Alberta; Canada
Genome Alberta ;
Genome Canada
PMID:19948758 nlx_143926, biotools:smpdb, r3d100012753 https://bio.tools/smpdb
https://doi.org/10.17616/R3TB93
SCR_004844 SMPDB (The Small Molecule Pathway Database), Small Molecule Pathway Database (SMPDB) 2026-02-14 02:00:45 95
NCBI Probe
 
Resource Report
Resource Website
10+ mentions
NCBI Probe (RRID:SCR_004816) NCBI Probe data repository, storage service resource, data or information resource, service resource, database Public registry of nucleic acid reagents designed for use in a wide variety of biomedical research applications including genotyping, gene expression studies, SNP discovery, genome mapping, and gene silencing. Probe records contain information on reagent distributors, probe effectiveness, and computed sequence similarities. The database is constantly updated, with over 11,000,000 probes available. Users may deposit their data into NCBI Probe Database. reagent, probe, registry, nucleic acid, gene expression, gene mapping, gene silencing, dna data bank, nucleic acid probe, gold standard, bio.tools is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: UniSTS
has parent organization: NCBI
Public, The community can contribute to this resource nlx_80513, r3d100010780, biotools:ncbi_dbprobe http://www.ncbi.nlm.nih.gov/sites/entrez?db=probe
https://bio.tools/ncbi_dbprobe
https://doi.org/10.17616/R3D041
SCR_004816 NCBI Probe Database, Entrez Probe Database, ProbeDB, Probe Database, dbProbe 2026-02-14 02:00:47 17
SLIQ
 
Resource Report
Resource Website
1+ mentions
SLIQ (RRID:SCR_005003) SLIQ software resource Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph. python, scaffolding, contig position, contig orientation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:23057825 biotools:sliq, OMICS_00048 https://bio.tools/sliq SCR_005003 Simple linear inequalities, SLiQ: Simple linear inequalities based Mate-Pair reads filtering and scaffolding 2026-02-14 02:01:03 3
European Genome phenome Archive
 
Resource Report
Resource Website
500+ mentions
European Genome phenome Archive (RRID:SCR_004944) EGA data repository, storage service resource, web service, data set, data or information resource, service resource, data access protocol, software resource Web service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects. The repository allows you to explore datasets from numerous genotype experiments, supplied by a range of data providers. The EGA''s role is to provide secure access to the data that otherwise could not be distributed to the research community. The EGA contains exclusive data collected from individuals whose consent agreements authorize data release only for specific research use or to bona fide researchers. Strict protocols govern how information is managed, stored and distributed by the EGA project. As an example, only members of the EGA team are allowed to process data in a secure computing facility. Once processed, all data are encrypted for dissemination and the encryption keys are delivered offline. The EGA also supports data access only for the consortium members prior to publication. phenomenon, trait, sequence, genotype, experiment, case-control, population, family study, snp, cnv, phenotype, genomic, gold standard, bio.tools is used by: Blueprint Epigenome
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: European Bioinformatics Institute
PMID:34791407 Restricted BioTools:ega, biotools:ega, r3d100011242, OMICS_01028, nlx_91316 https://ega-archive.org/
https://bio.tools/ega
https://bio.tools/ega
https://doi.org/10.17616/R3W619
SCR_004944 , The European Genome-phenome Archive, The European Genome-phenome Archive (EGA), EGA 2026-02-14 02:01:01 605
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2026-02-14 02:00:48 20
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace
https://sources.debian.org/src/sspace/
SCR_005056 2026-02-14 02:01:02 426
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets
 
Resource Report
Resource Website
1000+ mentions
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets (RRID:SCR_005040) data or information resource, software resource, database Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. Shotgun proteomics uses liquid chromatography-tandem mass spectrometry to identify proteins in complex biological samples. We describe an algorithm, called Percolator, for improving the rate of peptide identifications from a collection of tandem mass spectra. Percolator uses semi-supervised machine learning to discriminate between correct and decoy spectrum identifications, correctly assigning peptides to 17% more spectra from a tryptic dataset and up to 77% more spectra from non-tryptic digests, relative to a fully supervised approach. The yeast-01 data is available in tab delimetered format. The SEQUEST parameter file and target database for the yeast and worm data are also available. worm, yeast, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:17952086 biotools:percolator, nlx_98814 https://bio.tools/percolator SCR_005040 Percolator 2026-02-14 02:00:48 2482
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-02-14 02:00:50 1
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-02-14 02:00:48 89
SINA
 
Resource Report
Resource Website
100+ mentions
SINA (RRID:SCR_005067) SINA data analysis service, analysis service resource, production service resource, service resource, software resource Service to align and optionally taxonomically classify your rRNA gene sequences. The results can be combined with any other sequences aligned by SINA or taken from the SILVA databases by concatenation of FASTA files or using the ARB MERGE tool. Note: Submission is currently limited to at most 1000 sequences of at most 6000 bases each. If your requirements exceed this limitation, get Opens internal link in current windowSINA for local installation. alignment, taxonomic classification, rrna, gene sequence, fasta, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SILVA
is related to: ARB project
has parent organization: Max Planck Institute for Marine Microbiology; Bremen; Germany
PMID:22556368 Free, Available for download, Freely available OMICS_01438, biotools:sina https://bio.tools/sina
https://sources.debian.org/src/sina/
https://github.com/epruesse/SINA
SCR_005067 SINA Alignment Service, SILVA Incremental Aligner 2026-02-14 02:01:02 369
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/
https://bio.tools/g-blastn
SCR_005062 2026-02-14 02:01:02 0
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-02-14 02:01:03 1
MMAPPR
 
Resource Report
Resource Website
1+ mentions
MMAPPR (RRID:SCR_005092) MMAPPR software resource A software analysis pipeline for mapping mutations using RNA-seq that works without parental strain information, without the requirement of a pre-existing snp map of the organism, and without erroneous assumptions that recombination occurs at the same frequency across the genome. In addition, it compensates for the considerable amount of noise in RNA-seq datasets and simultaneously identifies the region where the mutation lies and generates a list of putative coding region mutations in the linked genomic segment. MMAPPR can utilize RNA-seq datasets from isolated tissues or whole organisms that are often generated for phenotypic analysis and gene network analysis in novel mutants. mutation, rna-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Utah; Utah; USA
PMID:23299975 Acknowledgement requested OMICS_01361, biotools:mmappr https://bio.tools/mmappr SCR_005092 Mutation Mapping Analysis Pipeline for Pooled RNA-seq 2026-02-14 02:01:02 7
FusionMap
 
Resource Report
Resource Website
50+ mentions
FusionMap (RRID:SCR_005242) FusionMap software resource An efficient fusion aligner which aligns reads spanning fusion junctions directly to the genome without prior knowledge of potential fusion regions. It detects and characterizes fusion junctions at base-pair resolution. FusionMap can be applied to detect fusion junctions in both single- and paired-end dataset from either gDNA-Seq or RNA-Seq studies. FusionMap runs under both Windows and Linux (requiring MONO) environments. Although it can run on 32 bit machine, it is recommended to run on 64-bit machine with 8GB RAM or more. If you have an ArrayStudio License, you can run the fusion detection easily through its GUI. windows, linux, c#, fusion gene, next-generation sequencing, gene, reference indexing, read filtering, fusion alignment, reporting, alignment, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21593131 Free, Non-commercial biotools:fusionmap, OMICS_00316 https://bio.tools/fusionmap SCR_005242 2026-02-14 02:01:05 88
rQuant
 
Resource Report
Resource Website
1+ mentions
rQuant (RRID:SCR_005150) rQuant software resource Software for quantitative detection of alternative transcripts with RNA-Seq data. The method, based on quadratic programming, estimates biases introduced by experimental settings and is thus a powerful tool to reveal and quantify novel (alternative) transcripts. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
PMID:20551130 biotools:rquant.web, OMICS_01286 https://bio.tools/rquant.web SCR_005150 rQuant: quantitative detection of alternative transcripts with RNA-Seq data 2026-02-14 02:01:03 1
ShoRAH
 
Resource Report
Resource Website
10+ mentions
ShoRAH (RRID:SCR_005211) ShoRAH software resource A software package that allows for inference about the structure of a population from a set of short sequence reads as obtained from ultra-deep sequencing of a mixed sample. The package contains programs that support mapping of reads to a reference genome, correcting sequencing errors by locally clustering reads in small windows of the alignment, reconstructing a minimal set of global haplotypes that explain the reads, and estimating the frequencies of the inferred haplotypes. linux, mac os x, windows, next-generation sequencing, c++, python, perl, structure, population, short sequence read, haplotype, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: ETH Zurich; Zurich; Switzerland
PMID:21521499 GNU General Public License, v3 biotools:shorah, OMICS_00231 https://bio.tools/shorah SCR_005211 Short Reads Assembly into Haplotypes, ShoRAH - Short Reads Assembly into Haplotypes 2026-02-14 02:00:50 35

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