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https://web.sas.upenn.edu/electronicshop/
Provides electronic design services and medical device development including Embedded systems (Firmware, Hardware, and Software solutions), Electronic prototype design services,PLM (Product Life-cycle Management) for electronic design. Supports Product Management from concept to final customer deployment. Expertise to make electronic device complete consumer product that can be deployed for mass production,Sustaining and maintenance engineering for electronic products,Consulting services in the areas of CE/FCC compliance, EMI, and ESD for lab products and certain consumer electronics,Troubleshooting and repair of released electronic systems.
Proper citation: University of Pennsylvania Penn Electronic Design Shop Core Facility (RRID:SCR_021107) Copy
Provides advanced instrumentation as well as high level technical and scientific expertise in multi dimensional Flow Cytometry and Cell Sorting, to facilitate science, improve the quality, and advance the scope of MSK research.
Proper citation: Memorial Sloan Kettering Cancer Center Flow Cytometry Core Facility (RRID:SCR_021105) Copy
https://www.colorado.edu/facility/biomolecular-x-ray-crystallography/
Provides resources for crystallization and structure determination of biological macromolecules and complexes. Supports research in the Department of Biochemistry. We are happy to extend our help to researchers from the broader CU community and to researchers outside the university, if time and availability allow us too.
Proper citation: Colorado University at Boulder Macromolecular X-ray Crystallography Core Facility (RRID:SCR_019310) Copy
http://www.medizinische-fakultaet-hd.uni-heidelberg.de/Home.111344.0.html
Multidisciplinary in vivo core facility equipped with equipment for detailed behavioral analyses and surgical procedures in context of mouse and rat models of neurological, cognitive and psychiatric disorders.Services include Behavioral analyses, Cognitive function,learning and memory, Sensory motor function, Emotional function and social interactions,Pain sensitivity tests, Disease models, Viral gene delivery, stereotactic and surgical manipulations, Optogenetics, In vivo electrophysiology.
Proper citation: University of Heidelberg Interdisciplinary Neurobehavioral Core Facility (RRID:SCR_019153) Copy
https://medicine.uky.edu/centers/cobre/genetic-technologies-core
Core provides services related to manipulation and delivery of nucleic acids to biological systems. Services include Production and titering of recombinant viral vectors,including Lentiviruses, Adenoviruses, and Adeno associated viruses;Subcloning;Tagging of open reading frames;Development of plasmids and/or RNAs for CRISPR/Cas manipulation;piggyBac transposon delivery systems;Real-time PCR analysis;Recombineering;In vitro transcription; Core maintains stock of plasmids that provide components for building constructs envisioned by investigator and provides consultative services.Provides training opportunities in the technologies described above, either as a for-credit, one semester class or on a project-related, fee-based basis.
Proper citation: University of Kentucky College of Medicine Genetic Technologies Core Facility (RRID:SCR_021285) Copy
https://cancer.dartmouth.edu/scientists-researchers/mouse-modeling
Supports generation and utilization of genetically modified mice, design and production of genetic constructs with methods including yeast and E.coli recombineering, ES cell targeting (transfection, drug selection, and expansion). Produces transgenic mice: DNA injections into oocytes, ES cell injections into blastocysts.Provides humanized immune system mouse models.Offers start to finish experiment services to assist your many needs, please ask for more info.Other services include animal husbandry, IP and IV injections, blood drawing, necropsy and surgeries- embryo transfers, ovariectomy, vasectomy, tumor removal.
Proper citation: Dartmouth Geisel School of Medicine Mouse Modeling Core Facility (RRID:SCR_021284) Copy
https://sites.manchester.ac.uk/bioms/
Core offers mass spectrometry services and associated technologies to the University of Manchester and beyond with focus on biological molecules such as proteins and metabolites in proteomics and metabolomics areas.Provides support from experimental design to advanced sample preparation and data processing and interpretation.
Proper citation: University of Manchester BioMS Core Facility (RRID:SCR_020987) Copy
http://www.rockefeller.edu/ddrc/
Core guides researchers in drug discovery by improving efficiency of their bioassays, identifying compounds and targets of function, and in utilizing technologies for measurement of drug/receptor interactions.Center also has spectroscopic and calorimetric equipment for use in studies of interactions of drugs with their targets.
Proper citation: Rockefeller University Fisher Drug Discovery Core Facility (RRID:SCR_020985) Copy
http://www.rockefeller.edu/genomics/
Core offers services and instruments to support genomics research. Houses Illumina NovaSeq, NextSeq, MiSeq sequencers, 10X Genomics Chromium Single Cell System, and Life Technologies QuantStudio 12K flex realtime PCR system. Provides several accessory instruments for sample quantity and quality validation: Agilent Bioanalyzer, Agilent TapeStation, NanoDrop spectrophotometer, and Qubit spectrophotometer.Offers full services for genomic DNA-Seq and RNA-Seq, specializing in preparation of libraries from very small amount of starting total RNA. Users can also prepare their own libraries and use the center�s sequencing-only services. Offers free consultations on experimental designs, library preparation options, sequencer choice, sequencing depth and coverage, and biological replicates.Performs initial sequencing data analysis for all users, and can assist with downstream analysis.
Proper citation: Rockefeller University Genomics Resource Center Core Facility (RRID:SCR_020986) Copy
https://pennstatehealthnews.org/topics/cryo-em/
Cryo-electron microscopy (cryo-EM) facility providesTitan Krios cryo-transmission electron microscope that is fully equipped for high-throughput data collection of the utmost quality possible. It has the ability to determine the atomic structure of a single protein or view molecules interacting in their cellular context. Provides guidance, training or data collection for researchers at the College of Medicine.Equipment includes Zeiss LSM 980 Cryo-Confocal Microscope,300 kV Krios Cryo-TEM for SPA and tomography, Equipped with Volta phase plates, bioquantum energy filter and K3 direct electron detector,200 kV thermionic JEOL 2100 for cryo-imaging, cryo-tomography, and standard imaging of stained grids.
Proper citation: Penn State Hershey College of Medicine cryo-EM Core Facility (RRID:SCR_021178) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/compchem/index.html
Core offers wide variety of services, including access to the Schrodinger platform and high-throughput computing. Services include examining molecular structures and mechanisms in atomic detail and provide graphically rich analysis suitable for inclusion in publications and grants.
Proper citation: University of Nebraska Medical Center Computational Chemistry Core Facility (RRID:SCR_021023) Copy
https://miap.eu/miap-unit/life-imaging-center/
Central core facility open to members of all faculties and the university clinic. Consists of 14 rooms in the Center for Integrative Signalling Analysis with 9 microscopy rooms with 20 microscope set-ups (3D-STED, confocal FLIM, two 2-photon confocal microscopes, 4 conventional confocal microscopes, lightsheet microscope, 4 high-end widefield ratio-imaging set-ups, 4 fluorescence stereo microscopes, 3 special set-ups for screening. LIC microscopes are hosted in Biosafety level S2 and S1 environments, connected to a large wet lab area and a cell culture room, both Biosafety level S2 classified. Additionally, the LIC offers a large computer lab with 12 high-end workstations for image processing and analysis. The LIC also covers two additional rooms, hosting 3 LSM systems in a neighboring building of the Signalling Campus Freiburg (SCF).
Proper citation: University of Freiburg Life Imaging Center Core Facility (RRID:SCR_020968) Copy
https://www.cityofhope.org/patients/departments-and-services/pathology
Department of Pathology at City of Hope combines state-of-the-art laboratories equipped with the latest diagnostic techniques and advanced instrumentation with superior investigative skills to accurately and rapidly identify even the rarest and most complex diseases. Our experts provide comprehensive services, from initial diagnosis to monitoring of prognostic indicators throughout the treatment process.
Proper citation: City of Hope Department of Pathology Core Facility (RRID:SCR_020974) Copy
https://www.umass.edu/ials/light-microscopy
Core provides resources for imaging model organisms, tissue, cells, biomaterials, and artificial structures and houses equipment including almost every light microscopy imaging modality presently available. Cell culture facilities are also available nearby as well as other routine items necessary for biological imaging and material imaging. This facility has been designated Nikon Centers of Excellence, thus providing unique opportunity for training, demonstration, instrument development, and research.We excel in use of telemicroscopy through use of remote imaging sessions, remote control of all instruments, and remote data analysis sessions available to all users.Provides training to all users that plan to conduct experimentation. Following an initial consultation in which experimental requirements, expected outcomes, and careful scrutiny of feasibility, training and/or access is arranged through the Director.
Proper citation: University of Massachusetts Light Microscopy Core Facility (RRID:SCR_021148) Copy
https://www.rockefeller.edu/cemrc/
Offers new cryo-electron microscopy tools available to University researchers, allowing for visualization of three-dimensional structures of molecules and macromolecular complexes in solution.
Proper citation: Rockefeller University Cryo Electron Microscopy Resource Center Core Facility (RRID:SCR_021146) Copy
https://www.bmh.manchester.ac.uk/research/facilities/electron-microscopy/
Offers expertise and equipment tailored for biological samples mostly. Houses four electron microscopes.Preparation laboratory includes range of specialised room temperature and cryo sample preparation equipment, ultramicrotomes and suite of computer workstations for image processing.Electron microscopy staff are available to train and assist.
Proper citation: University of Manchester Electron Microscopy Core Facility (RRID:SCR_021147) Copy
Coordinated, centralized, and dedicated program for procuring, processing, dispersing and assessing all types of biospecimens together with downstream histology services. CAP Accredited.
Proper citation: University of Chicago Human Tissue Resource Center Core Facility (RRID:SCR_019199) Copy
https://www.ualberta.ca/medicine/research/corefacilities/flow-cytometry-facility/index.html
Flow Cytometry Facility offers analytical flow cytometry, cell sorting and data analysis.Instruments include FACSArias, FACSCanto II, LSR-Fortessas, Attune NxT, and Amnis ImageStream mkII.
Proper citation: University of Alberta Faculty of Medicine and Dentistry Flow Cytometry Core Facility (RRID:SCR_019195) Copy
https://voices.uchicago.edu/confocal/
Offers microscopy imaging, including bright field color and DIC, fluorescence multi-dimension,TIRFM including bleaching, ablation, FLIM and high resolution, highspeed, high sensitivity, confocal, and physiologic techniques, STED, GSD3D, lightsheet selective plane illumination and lattice lightsheet structured illumination super resolution microscopy.
Proper citation: University of Chicago Integrated Light Microscopy Core Facility (RRID:SCR_019197) Copy
http://njms.rutgers.edu/research/mfrweb/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2022. Provides services in molecular biology with DNA sequencing, capillary and high throughput services, single cell sequencing services using 10X genomics and Drop-Seq platforms, Luminex, oligonucleotide synthesis (IDT), HPLC analysis and purification, real time PCR and others.
Proper citation: Rutgers New Jersey Medical School Molecular Resource Core Facility (RRID:SCR_019169) Copy
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