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https://www.augusta.edu/cancer/research/shared-resources/bioinformatics/
Georgia Cancer Center's Bioinformatics Core provides expertise in integrative computational based analysis solutions to basic, clinical, and translational research applications. Services include study design, analysis, and interpretation that may involve interaction with industry, government, and regulatory agencies in the areas of Clinical trials, Epidemiology, laboratory studies, in addition to data mining using local and national databases for hypotheses generation and scientific investigation.
Proper citation: Augusta University Bioinformatics Shared Resource Core Facility (RRID:SCR_027372) Copy
Electron microscopy facility specialising in cell biological electron microscopy for basic and medical research applications.
Proper citation: University College London LMCB Electron Microscopy Core Facility (RRID:SCR_027340) Copy
https://imss.lnma.mx/inicio.php
Core provides optical microscopy and histology services.
Proper citation: Mexican Social Security Institute National Laboratory of Advanced Microscopy IMSS Core Facility (RRID:SCR_027351) Copy
https://icahn.mssm.edu/research/resources/deans-cores/neuropathology
Provides access to collection of human postmortem brain tissues, including fresh, frozen, and formalin-fixed paraffin-embedded (FFPE) specimens, along with detailed clinical histories and neuropathological assessments. Available histology services include processing and embedding, slide sectioning for FFPE and cryosections, immunohistochemistry (IHC), immunofluorescence (IF), and advanced RNA assays such as RNAscope, BaseScope, and miRscope. High-resolution digital slide imaging is performed using the GT450 scanner. CoRE scientists also collaborate with investigators and trainees to support project development, method optimization and troubleshooting, data analysis.
Proper citation: Icahn School of Medicine at Mount Sinai Neuropathology Brain Bank and Research CoRE Facility (RRID:SCR_027565) Copy
https://icahn.mssm.edu/research/human-immune-monitoring-center
Core provides team of experts in the characterization of immune profiles and treatment responses across a diverse range of diseases, such as cancer, autoimmunity, allergy, and neuro-immune disorders. Offers equipment in the field for research at Genomic, cellular and proteomic analysis. Develops assays to balance innovation with protocols and operating procedures to ensure data quality and reproducibility.
Proper citation: Icahn School of Medicine at Mount Sinai Human Immune Monitoring Center Core Facility (RRID:SCR_027571) Copy
https://www.goodmancancer.ca/en/mcgill-integrated-core-for-animal-modeling-micam
Animal models of human disease are an invaluable research resource in the medical research community.Core provides services in the creation of animal models to the local research community and clients across Canada.
Proper citation: McGill University Integrated Core for Animal Modeling Core Facility (RRID:SCR_027541) Copy
https://medresearch.umich.edu/labs-departments/labs/nucleic-acid-therapeutics
Nucleic Acid Therapeutics Core accelerates the development of gene-targeted therapies by providing custom oligonucleotide synthesis, expert consultation, and platform for cross-disciplinary collaboration.
Proper citation: University of Michigan Medical School Nucleic Acid Therapeutics Core Facility (RRID:SCR_027422) Copy
Core provides flexible systems with built-in support for biometric data collection, dyadic interactions, and reproducible protocols. Provides access to pipelines that support reproducibility, custom data annotation, and seamless handoff to analysis tools in R, Python, and more. Provides access to IRB-ready templates and documentation, along with tested participant safety protocols and secure data management systems.
Proper citation: University of Michigan ISR-VR Lab Core Facility (RRID:SCR_027421) Copy
https://www.mayo.edu/research/core-resources/antibody-hybridoma-core/overview
Core can generate custom monoclonal antibodies in mouse and hamster systems. Can also produce large amounts of antibodies (of all species) and recombinant proteins in-vitro. Purification is also available for various systems.
Proper citation: Mayo Clinic Antibody Hybridoma Core Facility (RRID:SCR_027544) Copy
Facility provides training and access to advanced light microscopy systems at an hourly rate. In addition, we are available to consult with and support users at every stage of a project including: experimental design, sample preparation, image acquisition, analysis, and data preparation.
Proper citation: University of Connecticut Advanced Light Microscopy Core Facility (RRID:SCR_027547) Copy
https://research.manchester.ac.uk/en/equipments/core-facility-for-advanced-metal-development
Core supports all processing of metal related activity and houses equipment in the areas of thermomechanical processing, additive manufacturing, mechanical testing (including testing under a variety of environments), thermomechanical simulation/testing and heat treatment.
Proper citation: University of Manchester Advanced Metal Development Core Facility (RRID:SCR_027557) Copy
https://nmrcore.uhnresearch.ca/
NMR Core Facility is equipped with NMR spectrometers allowing researchers to Characterize bio-molecular structures at the atomic resolution with exquisite details;Identify protein interactions with binding partners in order to understand their architecture;Study protein dynamic;Study protein post-translational modifications acting as molecular switches;Study structure-function relationships of biological proteins to gain insight into biological processes in relation to human disease;Screening of High-throughput drug-like leads for novel therapeutic targets;Study Metabolites of interest.Core facility houses high-field NMR spectrometers equipped with cryogenically cooled probes (1H or 13C optimized) for enhanced sensitivity.
Proper citation: University Health Network Nuclear Magnetic Resonance Core Facility (RRID:SCR_027548) Copy
Reporting to the Division of Information Technology, and working in close partnership with the Office of Research, works with researchers to improve their project performance and secure computing resources not only at the university level but beyond, to National Labs and other high profile HPC resources.
Proper citation: University of South Carolina Research Computing Core Facility (RRID:SCR_027488) Copy
Core supports biomarker discovery and enhancing future cancer research in the areas of genomics, proteomics and epidemiology. Provides serialized collections of biospeciments throughout patient prognosis. Clinical time point collections are based on input from our expert surgical, medical, and radiation oncologist teams.
Proper citation: University Health Network McCain GU Biobank (RRID:SCR_027521) Copy
Core services include Imaging Modalities:MRI,PET-MRI,CT,PET-CT,Ultrasound / X-Ray,Interventional / Biopsies;Consultation:Pre-grant submission consultations,Pre-trial launch consultations / site initiation visists,Feasibility assessments MRI physics consultation; Protocol Development / Site Feasibility:Industry site feasibility questionnaires, Protocol development of medical imaging studies and clinical trials; Post-Processing of Images:Tumour measurements, Volumetric measurements.
Proper citation: University Health Network Joint Department of Medical Imaging Research Office JDMI RO Core Facility (RRID:SCR_027520) Copy
https://pmlivingbiobank.uhnresearch.ca/
Core provides services for the use of Xenograft (PDX) models listed in open global catalogue of PDX models for comprehensive search and attribute filtering support for clinico-pathological and molecular data. Molecular data and visualization of profiled models could be accessed through the institute's portal.
Proper citation: University Health Network Princess Margaret Living PDX Core Facility (RRID:SCR_027523) Copy
https://www.pmgenomics.ca/pmgenomics/
Core is dedicated to providing access to cost-effective and high quality genomics services including standard and custom-tailored DNA sequencing using Illumina technologies, epigenomics, panel-based profiling (Luminex and Nanostring) and functional genomics. Single cell genomics applications on variety of popular platforms.
Proper citation: University Health Network Princess Margaret Genomics Centre PMGC Core Facility (RRID:SCR_027524) Copy
https://www.clf.stfc.ac.uk/Pages/Octopus-new.aspx
National imaging facility that offers access to single molecule imaging, confocal microscopy, superresolution imaging, light sheet microscopy, optical trapping and cryoscanning electron microscopy. Offers expert guidance and advice for light and electron microscopy experiments alongside advanced instruments for fluorescence and electron microscopy.
Proper citation: Science and Technology Facilities Council Central Laser Facility OCTOPUS Microscopy Core Facility (RRID:SCR_027515) Copy
https://uhnbiospecimenservices.com/
Core provide services for the enhancement and progression of novel and innovative research and discovery. Provides human biospecimen samples such as: fresh frozen and formalin fixed paraffin embedded (FFPE) tissue, compartmentalized blood components such as serum, plasma, and whole blood peripheral blood mononuclear cells (PBMCs) and other biofluids, including saliva and urine; Tissue microarray (TMA) construction and quantitative image analysis of TMA sections, Laser capture microdissection (LCM), digital slide scanning, quantitative image, and pathological/clinical analysis for various tumour sites and DNA/RNA extraction; support and guidance to researchers and biobanks on accessing, collecting, and using human biospecimens and associated data for health research.
Proper citation: University Health Network Biospecimen Services Core Facility (RRID:SCR_027519) Copy
Core provides centralized service for performing technically challenging mouse models of cardiovascular disease, such as middle cerebral artery occlusion (MCAO) stroke model, coronary artery ligation model of myocardial ischemia, femoral artery ligation model of peripheral artery disease, and partial carotid artery ligation model of disturbed blood flow.
Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Surgical Models Core Facility (RRID:SCR_027497) Copy
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