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https://www.preventivemedicine.northwestern.edu/divisions/biostatistics/
Core where division members engage in statistical methods development and application, research design and statistical computing for health science research. Faculty interests encompass Bayesian methods, bioinformatics, causal inference, computational biology, clinical trials, diagnostic testing, longitudinal modeling, missing data modeling, observational data methods, semi-parametric models, spatial modeling, statistical genetics and survival analysis.
Proper citation: Northwestern University Biostatistics Collaborative Center (RRID:SCR_017943) Copy
http://mrsec.northwestern.edu/facilities/cleanroom/
Cleanroom facility is devoted to materials processing, growth, device fabrication, characterization and electronic and photonic materials. Provides microfabrication and thin film processing capabilities. Facility includes class 100 and 1000 cleanrooms.Training of equipment and assisted use within facility is available to provide necessary expertise.Provides centralized resource for deposition of metal, semiconductor and dielectric thin films, photolithography, etching, bonding, dicing, characterization and materials processing.
Proper citation: Northwestern University Materials Research Center Cleanroom Core Facility (RRID:SCR_017941) Copy
https://dtcore.northwestern.edu/
Core evaluates therapeutic agents and diagnostics, as well as existing therapeutics being considered for novel uses, through continued development and deployment of relevant animal models and in vitro cell lines and tissue models. Provides services to investigators to suit many needs, including those who may lack laboratory facilities and/or expertise for conducting experiments associated with preclinical therapeutic hypothesis testing.Services include Proliferation and Apoptosis Assays, Therapy-Response Experiments, Exploratory PK and Tox, Device Implantation and Monitoring,PDX Models,Immunization.
Proper citation: Northwestern University Developmental Therapeutics Core Facility (RRID:SCR_017948) Copy
http://proteomics.northwestern.edu/collaborate
Core offers multiple types of experiments from simple protein identification to protein quantitation. Performs traditional bottom-up proteomics, where proteins are digested with enzyme prior to analysis and intact, top-down proteomics analyses. Services include proteins identification after in-gel or in-solution digestion, top-down mass spectrometry to preserve post-translationally modified forms of proteins present in vivo by measuring them intact, IP-MS Pulldown,BioID service to identify target of biotin ligase that has been tagged onto their protein via traditional cloning methods,Untargeted Quantitative Peptide Proteomics,Targeted Quantitative Peptide Proteomics,Epiproteomic Histone Modification Panel A,Epiproteomic Histone Modification Panel B,Untargeted Metabolomics,Phosphoproteomics,PTM Scan,ChIP-MS.
Proper citation: Northwestern University Proteomics Core Facility (RRID:SCR_017945) Copy
https://www.microscopyu.com/museum/eclipse-e600
Microscope equipped with CFI60 infinity optical system, providing images in all applications. Incorporates specifications adopted for CFI60 series objectives, including 60 millimeter parfocal distance, 25 millimeter thread size, and standard 22 millimeter field of view. Main components of CFI60 infinity optical system include objective, tube lens to converge light beam, and eyepiece lens to enlarge intermediate image. Fluorescence microscope that has detachable substage, 12 volt 100 watt tungsten halide lamp, filter magazine, and choice of sextuple nosepiece or sextuple DIC nosepiece.Has objectives for brightfield, darkfield, Nomarski DIC, epi fluorescence, or phase contrast techniques.
Proper citation: Nikon Eclipse E600 Fluorescence Microscope (RRID:SCR_018606) Copy
http://www.biotech.ufl.edu/cores/monoclonal-antibody/
Core develops new mouse monoclonal antibodies for investigators to use in basic and applied research.Provided services include immunization of mice, cell fusion, cell cloning, screening by ELISA and Western blot, monoclonal antibody production, purification and labeling, monoclonal antibody analyses such as antibody/antigen affinity measurements, epitope binning and identification of matched antibody pairs. Customer training on select self-service instruments is also offered.
Proper citation: University of Florida ICBR Monoclonal Antibody Core Facility (RRID:SCR_019147) Copy
http://www.biotech.ufl.edu/cores/electron-microscopy/
ICBR Electron Microscopy supports researchers in visualizing microscopic structures through imaging projects and user training. Provided serives include room temperature and cryo transmission and scanning electron microscopy, confocal laser scanning microscopy, sample preparation and user training.
Proper citation: University of Florida ICBR Electron Microscopy Core Facility (RRID:SCR_019146) Copy
https://case.edu/medicine/genomics/
Core provides centralized resource working to take difficulty out of Next Generation Sequencing projects for both novice and experienced users alike. Provides assistance in all facets of experimentation from design to data analysis including grant and manuscript preparations.Offers NGS, Sanger, Informatics and Genotyping services based off of Illumina platform.
Proper citation: Case Western Reserve University Genomics Core Facility (RRID:SCR_019021) Copy
https://www.colorado.edu/center/ciest/
Provides centrally managed experimental testing facility offering geotechnical centrifuge, structural dynamics and materials testing. Facility boasts unique large-scale, fast loading rate, gravitational and environmental control capabilities.
Proper citation: Colorado University at Boulder Center for Infrastructure, Energy, and Space Testing Core Facility (RRID:SCR_018987) Copy
Core provides number of specialized measuring tools for optical and surface characterization, as well as expertise in fiber optics.Fabrication facility is clean room for fabrication at micron and nanometer scale. Training and consultation is provided.
Proper citation: Colorado University at Boulder JILA Keck Lab and Fabrication Core Facility (RRID:SCR_018984) Copy
https://med.virginia.edu/molecular-electron-microscopy-core/
Facility dedicated to high resolution electron cryomicroscopy and electron cryotomography. It houses three electron microscopes,120kV Spirit, 200kV F20, and 300kV Titan Krios. These microscopes are available to researchers either for direct use, or aided by MEMC personnel, to collect data aimed at high resolution structural biology projects.
Proper citation: University of Virginia School of Medicine Molecular Electron Microscopy Core Facility (RRID:SCR_019031) Copy
http://www.medizinische-fakultaet-hd.uni-heidelberg.de/Home.111344.0.html
Multidisciplinary in vivo core facility equipped with equipment for detailed behavioral analyses and surgical procedures in context of mouse and rat models of neurological, cognitive and psychiatric disorders.Services include Behavioral analyses, Cognitive function,learning and memory, Sensory motor function, Emotional function and social interactions,Pain sensitivity tests, Disease models, Viral gene delivery, stereotactic and surgical manipulations, Optogenetics, In vivo electrophysiology.
Proper citation: University of Heidelberg Interdisciplinary Neurobehavioral Core Facility (RRID:SCR_019153) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/nanoimaging/index.html
Provides service and expert advice to researches in their projects related to nanoimaging studies of molecular systems at single molecule and single cell levels utilizing Atomic Force Microscope, combination of Atomic Force Microscope with Fluorescence Optical Microscope, combination of Atomic Force Microscope with Raman Spectroscopy.
Proper citation: University of Nebraska Medical Center Nanoimaging Core Facility (RRID:SCR_018828) Copy
http://www.med.nyu.edu/ocs/cytometry-and-cell-sorting-core
Facility provides cytometry and cell sorting services. Services include immunophenotyping, cell cycle analysis, and intracellular fluorophore detection. Services can be tailored to research needs, certified cytometrists are available to help plan experiments. Offers online and hands-on training in use of cell analyzers and analysis software.
Proper citation: New York University School of Medicine Langone Cytometry and Cell Sorting Core Facility (RRID:SCR_018827) Copy
https://labnodes.vanderbilt.edu/vger
Provides services, consultation, and collaborations to enable generation, storage and regeneration of genetically altered mice.Services include CRISPR-Cas9 Mouse Editing, Pronuclear Microinjection of DNAs,Sperm or Embryo Cryopreservation,In vitro Fertilization and Rederivation,Genome-Editing Design and Analysis Services.
Proper citation: Vanderbilt University Genome Editing Resource Core Facility (RRID:SCR_018826) Copy
https://research.uky.edu/abebc
Core primary focus is to identify mechanisms linking obesity to cardiovascular disease. Provides equipment and technical expertise for measurement of lean/fat mass and whole body metabolism in mice. Provides equipment for computerized quantitative measurement of oxygen consumption, food intake, water intake, and physical activity in mice.Echo MRI is utilized for non invasive quantitative assessment of lean and fat mass.
Proper citation: Kentucky University, Lexington, Energy Balance and Body Composition Core Facility (RRID:SCR_018825) Copy
https://www.biotech.iastate.edu/Hybridoma/
Core provides services for monoclonal or polyclonal antibodies production,animal immunization, cell fusion and hybridoma culture maintenance, cell culture and maintenance of other cell lines used in biotechnology and virology labs, large scale mammalian cell culture (bioreactor), blood sera collection, antibody purification and isotyping, cryopreservation and cryostorage of cell lines, and ELISA tests.
Proper citation: Iowa State University Hybridoma Core Facility (RRID:SCR_018829) Copy
https://www.danforthcenter.org/our-work/core-facilities/advanced-bioimaging-laboratory/
Core provides instruments for live cell imaging including Leica SP8-X confocal microscope and other fluorescence microscopes. Facility provides workstation for confocal image processing, ancillary equipment required for transmission electron microscopy. Services are provided as self services after user training by IMF staff or as full services done by core facility staff.
Proper citation: Donald Danforth Plant Science Center Advanced Bioimaging Laboratory Core Facility (RRID:SCR_018951) Copy
https://isb3d.pharmacy.vcu.edu/resources/
Core provides services for Molecular Modeling, Biophysical Techniques, X-ray Crystallography, Protein Production,High Throughput Screening. Provided instruments to use after reservation include Clariostar Multimode Plate Reader, Echo 550 Acoustic Liquid Handler, X-Ray Diffractometer.
Proper citation: Virginia Commonwealth University School of Pharmacy Institute for Structural Biology, Drug Discovery and Development Core Facility (RRID:SCR_018832) Copy
Provides development and support of genomics-based research, serving investigators in Nevada and beyond. Staff can be contracted for select services including ABI 3130 DNA sequencing, BD FACSCalibur flow cytometry, Affymetrix microarray processing, Agilent 2100 Bioanalyzer analysis and Qubit analysis. Facility also provides equipment and training for real-time PCR, Western blot/gel/microarray scanning, and analysis of DNA, RNA and protein samples.
Proper citation: Nevada University Genomics Core Facility (RRID:SCR_018272) Copy
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