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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CCPN Data Model
 
Resource Report
Resource Website
CCPN Data Model (RRID:SCR_016982) software application, data processing software, data repository, database, storage service resource, software resource, data storage software, service resource, data or information resource Model to cover data for macromolecular NMR spectroscopy from the initial experimental data to the final validation. Used for the large scale data deposition, data mining and program interoperability. Enables movement from one software package to another without difficulties with data conversion or loss of information. Works with CcpNmr Analysis software for analysis and interactive display, CcpNmr FormatConverter for allowing transfer of data from programs used in NMR to and from the Data Model, and the CLOUDS software for automated structure calculation and assignment. Used within the CCPN software suite for NMR spectroscopy and at the BioMagResBank for converting existing deposited restraint lists to a standard IUPAC nomenclature. data, macromolecular, NMR, spectroscopy, deposition, mining, interoperability, conversion is related to: Biological Magnetic Resonance Data Bank (BMRB)
has parent organization: Collaborative Computing Project for NMR
works with: CCPN Analysis
works with: CCPN Analysis
EU ;
BBSRC ;
NLM P41 LM005799;
NIGMS GM67965
PMID:15815974
PMID:15613391
PMID:21953355
Free, Public SCR_016982 The CCPN Data Model 2026-02-16 09:49:08 0
SerialEM
 
Resource Report
Resource Website
100+ mentions
SerialEM (RRID:SCR_017293) data acquisition software, software application, data processing software, software resource Software tool for automated EM data acquisition. Used for efficient tilt series acquisition and interface for image capture, display, and storage and for control of some aspects of microscope function. automated, data, acquisition, tilt, image, capture, display, storage, microscope NCRR RR00592;
NIGMS P01 GM61306
PMID:16182563 Restricted SCR_017293 2026-02-16 09:49:12 213
Protomo
 
Resource Report
Resource Website
1+ mentions
Protomo (RRID:SCR_017296) data processing software, software application, software resource, image processing software Software tool for electron tomography and 3D image processing. Software package used in electron tomography for marker free alignment and 3D reconstruction of tilt series. Tomography software package distributed for linux operating system and developed by Hanspeter Winkler. electron, tomography, 3D, image, processing NIGMS GM30598;
NIGMS GM64346
PMID:16973379 Restricted SCR_017296 2026-02-16 09:49:12 4
RaptorX
 
Resource Report
Resource Website
100+ mentions
RaptorX (RRID:SCR_018118) software application, web service, data access protocol, software resource, simulation software Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model. Protein structure predictor, 3D structure, protein sequence, secondary and tertiary structure, binding site, solvent accessibility, disordered region, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
NIGMS R01 GM089753;
NSF DBI 0960390
PMID:21987485 Restricted biotools:raptorx https://bio.tools/raptorx SCR_018118 2026-02-16 09:49:26 149
piNET
 
Resource Report
Resource Website
1+ mentions
piNET (RRID:SCR_018693) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Web platform for downstream analysis and visualization of proteomics data. Server that facilitates integrated annotation, analysis and visualization of quantitative proteomics data, with emphasis on PTM networks and integration with LINCS library of chemical and genetic perturbation signatures in order to provide further mechanistic and functional insights. Primary input for server consists of set of peptides or proteins, optionally with PTM sites, and their corresponding abundance values. Analysis, visualization, proteomics data, integrated annotation, quantitative proteomics data, PTM network, LINCS library integration, genetic perturbation signature, peptide, protein, post translational modification site, PTM site, data is related to: LINCS Project NHLBI U54 HL127624;
NIEHS P30 ES006096;
NIMH R01 MH107487;
NCI T32 CA236764;
NCATS UL1 TR001425;
NIGMS U01 GM120953
DOI:10.1093/nar/gkaa436 Free, Freely available SCR_018693 2026-02-16 09:49:33 4
Monocle3
 
Resource Report
Resource Website
100+ mentions
Monocle3 (RRID:SCR_018685) software application, data processing software, software toolkit, data analysis software, software resource Software analysis toolkit for single cell RNA-seq. Used for single cell RNA-Seq experiments. Unsupervised algorithm that increases temporal resolution of transcriptome dynamics using single-cell RNA-Seq data collected at multiple time points. Data analysis, singel cell RNAseq data, single cell RNAseq experiment, transcriptome dynamics has parent organization: University of Washington; Seattle; USA NIH Office of the Director DP2 OD00667;
NIGMS P01 GM099117;
NIH Office of the Director DP2 0D008514;
NHGRI P50 HG006193;
Single Cell Genomics initiative
PMID:24658644 Free, Available for download, Freely available https://github.com/cole-trapnell-lab/monocle3 SCR_018685 Monocle, Monocle 3 2026-02-16 09:49:31 270
BpForms
 
Resource Report
Resource Website
BpForms (RRID:SCR_018653) data access protocol, software resource, web service, software toolkit Software toolkit for unambiguously describing molecular structure of DNA, RNA, and proteins, including non-canonical monomeric forms, crosslinks, nicks, and circular topologies. Aims to help epigenomics, transcriptomics, proteomics, systems biology, and synthetic biology researchers share and integrate information about DNA modification, post-transcriptional modification, post-translational modification, expanded genetic codes, and synthetic parts. Molecular structure description, DNA, RNA, protein, modification, epigenetics, transcriptomics, post transcriptional modification, post translational modification, bio.tools uses: BcForms
is used by: ObjTables
is used by: Datanator
is listed by: Debian
is listed by: bio.tools
is related to: BcForms
is related to: ObjTables
NIBIB P41 EB023912;
NSF 1649014;
NIGMS R35 GM119771
PMID:32423472 Free, Freely available biotools:bpforms https://bio.tools/bpforms SCR_018653 2026-02-16 09:49:30 0
ObjTables
 
Resource Report
Resource Website
ObjTables (RRID:SCR_018652) software application, data processing software, software toolkit, data management software, software resource Software toolkit for creating reusable datasets that are both human and machine readable, combining spreadsheets with schemas including classes, their attributes, type of each attribute, and possible relationships between instances of classes.Consists of format for describing schemas for spreadsheets, numerous data types for science, syntax for indicating class and attribute represented by each table and column in workbook, and software for using schemas to rigorously validate, merge, split, compare, and revision datasets. Used for supplementary materials of journal article, as well as for emerging domains which need to quickly build new formats for new types of data and associated software with minimal effort. Creating reusable dataset, combining spreadsheet with schema, spreadsheet, table, supplementary material, schema, object relational map, validation, bio.tools uses: BpForms
uses: BcForms
is listed by: bio.tools
is listed by: Debian
is related to: BpForms
NIBIB P41 EB023912;
NSF 1649014;
NIGMS R35 GM119771
Free, Freely available biotools:objtables https://bio.tools/objtables SCR_018652 2026-02-16 09:49:33 0
PhyDyn
 
Resource Report
Resource Website
10+ mentions
PhyDyn (RRID:SCR_018544) software application, software resource, simulation software Sofware package for performing Bayesian phylogenetic inference under models that deal with structured populations with complex population dynamics. Enables simultaneous estimation of epidemiological parameters and pathogen phylogenies. Epidemiological modelling in BEAST. Bayesian phylogenetic inference, epidemiological modelling, epidemiological parameter estimation, pathogen phylogeny estimation is related to: BEAST2
is related to: BEAST
NIGMS U01 GM110749;
MRC Centre for Global Infectious Disease Analysis
PMID:30422979 Free, Available for download, Freely available SCR_018544 2026-02-16 09:49:31 10
MyGene.info
 
Resource Report
Resource Website
10+ mentions
MyGene.info (RRID:SCR_018660) service resource, data access protocol, software resource, web service Web service for querying or retrieving gene annotation data. Querying gene, gene, annotation, gene annotation, annotation data, gene annotation data, retrieving gene annotation data, bio.tools is listed by: Debian
is listed by: bio.tools
NHGRI U01 HG008473;
NIGMS GM083924;
NIGMS U54 GM114833;
NHGRI U01 HG006476;
NCI K22 CA188163;
NCATS UL1 TR001114;
Scripps Translational Science Institute
DOI:10.1186/s13059-016-0953-9 Free, Freely available biotools:mygene.info, BioTools:mygene.info https://bio.tools/mygene.info
https://bio.tools/mygene.info
https://bio.tools/mygene.info
SCR_018660 2026-02-16 09:49:30 20
ROSIE
 
Resource Report
Resource Website
1+ mentions
ROSIE (RRID:SCR_018764) ROSIE web application, application programming interface, software resource, data access protocol Unified web framework for Rosetta applications. Web interface for selected Rosetta protocols. Web front end for Rosetta software suite. Provides common user interface for Rosetta protocols, stable application programming interface for developers to add additional protocols, flexible back-end to allow leveraging of computer cluster resources shared by Rosetta Commons member institutions, and centralized administration by Rosetta Commons to ensure continuous maintenance. Offers general and speedy paradigm for serverification of Rosetta applications. Lowers barriers to Rosetta use for broader biological community. Web interface for Rosetta, Rosetta online server, Rosetta application serverification, Rosetta user interface works with: Rosetta NIGMS R01 GM073151;
NIGMS R01 GM07822;
NIGMS R21 GM102716;
NCRR R00 RR024107;
NCI U54 CA143907;
NEI PN2 EY016586;
NIGMS T32 GM 88118;
Taiwan Governmental Scholarship for Study Abroad ;
Howard Hughes Medical and Institute International Student Research Fellowship ;
NSF
PMID:23717507 Restricted https://rosie.rosettacommons.org/ SCR_018764 Rosetta Online Server that Includes Everyone 2026-02-16 09:49:33 7
GOnet
 
Resource Report
Resource Website
1+ mentions
GOnet (RRID:SCR_018977) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Web tool for interactive Gene Ontology analysis of any biological data sources resulting in gene or protein lists. Gene Ontology, interactive analysis, data, gene, protein, gene list, protein list, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
works with: Gene Ontology
NIH Common Fund ;
NIGMS ;
NHGRI R24 HG010032;
NIAID U19 AI118610;
NIAID U19 AI118626
PMID:30526489 biotools:GOnet https://github.com/mikpom/gonet
https://bio.tools/GOnet
SCR_018977 2026-02-16 09:49:37 3
CAIRN
 
Resource Report
Resource Website
CAIRN (RRID:SCR_019101) software application, data processing software, data visualization software, web service, data access protocol, software resource Web tool to graph all copy number alterations present in segment file. Custom data is permitted. Allows to display copy number alterations which overlap user specified region, to quantify number of amplified CNAs and deleted CNAs. Visualization tool to explore copy number alterations discovered in published cancer datasets. Intended to help oncology community observe of relative rates of amplification, deletion, and mutation of interesting genes and regions. Deleted CNAs quantification, Copy Number Alterations, segment file, data visualization, published cancer datasets CNAs, amplified CNA quantification Nine Girls Ask Foundation ;
NCI CA207729;
NIGMS GM132055;
NCI CA107263;
NCI CA177519;
NCI CA102310;
NIA AG033082;
NCI P30 CA138313
PMID:31923184 Free, Available for download, Freely available https://github.com/jrdelaney/CAIRN SCR_019101 Copy Alterations Intuitive Rendering Navigator 2026-02-16 09:49:36 0
trRosetta
 
Resource Report
Resource Website
50+ mentions
trRosetta (RRID:SCR_021181) service resource, software application, software resource, simulation software Software tool for fast and accurate protein structure prediction. Builds protein structure based on direct energy minimizations with restrained Rosetta. Restraints include inter-residue distance and orientation distributions, predicted by deep residual neural network. Homologous templates are included in network prediction to improve accuracy for easy targets. protein structure, restraint-guided structure generation, protein structure prediction uses: Rosetta National Natural Science Foundation of China ;
Fok Ying-Tong Education Foundation ;
Key Laboratory for Medical Data Analysis and Statistical Research of Tianjin ;
Thousand Youth Talents Plan of China ;
China Scholarship Council ;
NIGMS R01 GM092802;
NIH Office of the Director DP5 OD026389
PMID:31896580 Free, Freely available https://github.com/gjoni/trRosetta SCR_021181 transformed restrained Rosetta 2026-02-16 09:49:57 67
Motif Mutation Analysis for Regulatory Genomic Elements
 
Resource Report
Resource Website
500+ mentions
Motif Mutation Analysis for Regulatory Genomic Elements (RRID:SCR_021902) MMARGE software application, data processing software, software toolkit, data analysis software, software resource Software package that integrates genome wide genetic variation with epigenetic data to identify collaborative transcription factor pairs. Optimized to work with chromatin accessibility assays such as ATAC-seq or DNase I hypersensitivity, as well as transcription factor binding data collected by ChIP-seq. Used to identify combinations of cell type specific transcription factors while simultaneously interpreting functional effects of non-coding genetic variation. genome wide genetic variation, epigenetic data, identify collaborative transcription factor pairs, interpreting functional effects, non-coding genetic variation NCI CA173903;
NIGMS GM085764;
NIDDK DK091183;
NHLBI R00 123485
PMID:29893919 Free, Available for download, Freely available SCR_021902 2026-02-16 09:50:11 608
3DRefine
 
Resource Report
Resource Website
10+ mentions
3DRefine (RRID:SCR_021883) data access protocol, software resource, web service Interactive web server for efficient protein structure refinement with capability to perform web based statistical and visual analysis. efficient protein structure refinement, statistical and visual analysis NIGMS R01 GM093123 DOI:10.1093/nar/gkw336 Free, Freely available SCR_021883 2026-02-16 09:50:12 20
Protofilament Bending Models
 
Resource Report
Resource Website
1+ mentions
Protofilament Bending Models (RRID:SCR_023062) source code, software resource Code is written to be run with Matlab version r2020b or higher. Model accepts wave assay pulse amplitude data, and simultaneously solves and fits protofilament deflection models to deduce fundamental biophysical properties of microtubule protofilaments. Matlab, protofilament, microtubule, strain energy, GTP hydrolysis uses: MATLAB NIGMS R35GM134842 DOI:10.7554/eLife.83225 Free, Available for download, Freely available SCR_023062 2026-02-15 09:22:58 1
abSENSE
 
Resource Report
Resource Website
1+ mentions
abSENSE (RRID:SCR_023223) source code, software resource Software to interpret undetected homolog.Method that calculates probability that homolog of given gene would fail to be detected by homology search in given species, even if homolog were present and evolving normally. undetected homolog, gene homolog detection failure, homology search, lineage-specific genes, homology detection failure Howard Hughes Medical Institute ;
NHGRI R01-HG009116;
NIGMS RO1-GM43987;
NSF 1764269;
Simons Center for the Mathematical and Statistical Analysis of Biology 594596;
Harvard University
PMID:33137085 Free, Available for download, Freely available http://www.eddylab.org/abSENSE/ SCR_023223 2026-02-15 09:23:06 1
PTNet
 
Resource Report
Resource Website
PTNet (RRID:SCR_022975) source code, software resource Graph based learning model for protein expression estimation by considering miRNA-mRNA interactions. Estimates protein levels by considering miRNA-mRNA interaction network, mRNA expression and miRNA expression. protein level, protein expression estimation, miRNA-mRNA interactions, mRNA expression, miRNA expression, NSF III1755761;
NIGMS R01GM113952;
NIDDK DK097771
DOI:10.1093/bib/bbab264 Free, Available for download, Freely available SCR_022975 2026-02-15 09:22:56 0
AutoDockTools
 
Resource Report
Resource Website
1000+ mentions
AutoDockTools (RRID:SCR_026401) ADT software application, software resource Software graphical user interface to help to set up which bonds will treated as rotatable in the ligand and to analyze dockings. Used for automated docking with selective receptor flexibility. Designed to predict how small molecules, such as substrates or drug candidates, bind to receptor of known 3D structure. automated docking, selective receptor flexibility, predict binding, bind to receptor of known 3D structure, ligand, analyze dockings NIGMS RO1 GM069832 PMID:19399780 Free, Available for download, Freely available https://autodock.scripps.edu/ SCR_026401 AutoDockTools: the Graphical User Interface for AutoDock 2026-02-15 09:24:02 1612

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