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https://www.ohsu.edu/pharmacokinetics-core

Core for analysis of drugs and their metabolites and bio-molecules such as simple peptides, oligonucleotides, carbohydrates, lipids, fatty acids and steroids. Provides open access to laboratory where users prepare and analyze their own samples by HPLC, GC/MS or LC/MS on equipment maintained by core personnel. Provides analysis of samples including development of analytical methods, sample preparation, and data analysis for clinical trials as well as basic science investigations.

Proper citation: OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility (RRID:SCR_009963) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/advanced-imaging-research-center/about-advanced-imaging-research-center

Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities.

Proper citation: OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5946-2efe-55da-381e80000000

The Biostatistics Center provides support to MGH investigators, as well as serving as a Coordinating Center for several NIH-supported projects. The Center''s staff includes biostatisticians, physicians, research nurses, data managers, project managers, research assistants, and computing staff.

Proper citation: MGH Biostatistics Center (RRID:SCR_009913) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c83-8c33-fbab-3b8480000000

Core facility that provides the following services: Custom peptide synthesis service. The Biological Chemistry Resource Center (BCRC) at the Department of Chemistry has been established to provide an open access user facility for state-of-art biophysical analytical instrumentation. The goal of the center is not only to provide access to instrumentation, but also supply the graduate student and post-doc user community with a firm understanding of the scientific principles behind the techniques and on-site expertise to ensure successful experimentation. Instrumentation access will be available to the entire University of Pennsylvania research community.

Proper citation: Penn Biological Chemistry Resource Center (RRID:SCR_009999) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-3afd-4e95-62b8-f47280000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Monoclonal antibody development. The Oregon Stem Cell Center Monoclonal Antibody Core is focused on developing monoclonal antibodies that aid investigators in the identification and isolation of novel stem and progenitor cell populations. To enable isolation of live stem cells, personnel within the Monoclonal Antibody Core develop monoclonal antibodies directed against cell surface antigens. Personnel within the laboratory are highly skilled in all aspects of monoclonal antibody generation and characterization, and work closely with investigators throughout the entire immunization, fusion, and screening process. The monoclonal antibody core offers a full complement of services related to the development of monoclonal antibodies.

Proper citation: Oregon Stem Cell Center Monoclonal Antibody Core (RRID:SCR_009997) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000141-9868-14b8-91c7-0c6080000000

Core facility that provides the following services: Hydrogel consultation service, ECM-coated acrylamide hydrogels, Hands-on guidance for cell lysis and molecular/cellular analysis, Preparation of acrylamide-based hydrogel training, Second harmonic generation microscopy, Atomic force microscopy. The Biomechanics Core works with ITMAT faculty from Penn, ITMAT partner institutions, and members of the ITMAT Program in Translational Biomechanics. Consultation and initial pilot experiments performed with the Biomechanics Core are free-of-charge to ITMAT faculty from Penn, ITMAT partner institutions, and members of the ITMAT Program in Translational Biomechanics.

Proper citation: Penn BioMechanics Core Facility (RRID:SCR_009998) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-865d-c25e-048a-d9aa80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6, 2022. Core facility that provides the following services: Consultation on protocol development and design process, Exercise testing service, Dual energy x-ray absorptiometry service. The Bionutrition Unit provides nutrition, body composition, and energy expenditure services. Bionutritionist and research kitchen staff are highly experienced and trained to assist investigators with the design and implementation of research meals, feeding studies, and related research. The Bionutrition Unit also provides a variety of energy expenditure and body composition measurement services using a range of equipment.

Proper citation: Oregon Clinical and Translational Research Institute Bionutrition Unit (RRID:SCR_009995) Copy   

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https://www.ohsu.edu/octri/clinical-and-translational-research-center

Provides nursing, bionutrition, study coordination, and laboratory services and support. Laboratory is designed and equipped to perform both basic and specialized research assays and sample processing in support of translational research studies and trials. Laboratory staff have extensive experience in performance of wide variety of analytical and genetic based assays and procedures.

Proper citation: OHSU Oregon Clinical and Translational Research Center Core Facility (RRID:SCR_009996) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/proteomics-shared-resource

Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU.

Proper citation: OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-00c9-007b-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: G-banded karyotyping, Sister chromatid exchange service, Fluorescent in situ hybridization, Chromosome breakage and radial formation analysis, Ploidy/Aneuploidy Assessment, Mitotic index service. A fee-for-service cytogentics laboratory available to genetics researchers to assist in development and execution of cytogenetics experiments for research purposes. Through rigorous standardization of protocols and customized experiment development, the OHSU Research Cytogenetics Core Laboratory provides high quality metaphase and interphase cytogenetic data to the OHSU research community. Services are also available to non-profit and commercial investigators located in Oregon and elsewhere.

Proper citation: OHSU Research Cytogenetics Core Laboratory (RRID:SCR_009992) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-00ce-7b4f-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. The Neuropathology Core of the Layton Center for Aging and Alzheimer?s Disease Center is dedicated to studying, through autopsy, the brains of individuals who have been followed longitudinally in the Oregon Alzheimer?s Disease Center Clinical Core. Requests for tissue from the Oregon Brain Bank should be directed to Dr. Randall Woltjer. Dr. Woltjer will be glad to communicate with investigators regarding their tissue needs and to assist them in identifying suitable materials for their studies. Material Transfer Agreements between the requesting and sending institutions are needed before shipment.

Proper citation: OHSU Neuropathology Core (RRID:SCR_009988) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/medicinal-chemistry-core/nmr

Core facility that provides the following services: NMR instrument training. A facility that uses a state-of-the-art NMR spectrometer to verify or determine the structure of organic molecules. Housed in the Department of Physiology and Pharmacology, it is designed to exploit the power of designed small molecules as probes of protein and cellular function and to provide the foundation for the development of prototypic therapeutic agents.

Proper citation: OHSU Nuclear Magnetic Resonance Core Facility (RRID:SCR_009989) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013b-95a6-bd56-c825-3bd680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Automated DNA sequencing, Realtime PCR analysis and SNP analysis, Automated DNA and RNA preps using robotics, Lentiviral vector preparation for cDNA and shRNA transduction and infection, Semi-automated large-scale genomic DNA preparations., Freezing, thawing, and amplification of cell lines, Preparation of both routine and exotic cell culture medium. The Molecular and Cellular Biology Core provides services, reagents and training for all aspects of molecular biology and cell culture. Services include DNA sequencing, real-time PCR, genotyping, robotic RNA and DNA purification, monkey-specific cDNAs, and customized media and buffers for cell culture. The core also produces lentiviral vectors for cDNA and shRNA delivery. Core personnel assist researchers in maintaining and storing cell lines. The core makes available state-of-the-art equipment, including a 969capillary DNA sequencer, realtime qRT-PCR platforms, and fluorometers for cell-based kinetic analyses..

Proper citation: OHSU Molecular and Cellular Biology Core Laboratory (RRID:SCR_009986) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-24fd-6e5c-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Monoclonal antibody generation, Scaleup production and purification of antibody from existing cell lines. The VGTI Monoclonal Core offers two basic services: the generation of new monoclonal antibodies and the scaleup production and purification of antibody from existing cell lines (a stand -alone phase IV).

Proper citation: OHSU Monoclonal Antibody Core Laboratory (RRID:SCR_009987) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-24ff-c95f-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Flow cytometry training service, Cell sorting service, Specialized flow cytometric assays. The mission of the Immunology Support Core (ISC) is to develop and provide a wide range of state-of-the-art services, assays, and training in support of NIH-sponsored immunology research involving nonhuman primates (NHP).

Proper citation: OHSU Immunology Support Core Flow Cytometry Unit (RRID:SCR_009981) Copy   

•   Source: SciCrunch Registry

http://msm.eagle-i.net/i/0000012b-00c2-775d-353c-df7f80000000

Core facility that provides the following services: Basic animal care service, Clinical and health monitoring service, Humane euthanasia service, Animal disposal service, Animal quarantine service, Necropsy and diagnostics service, Animal vaccination service, Animal use consultation service, Breeding service, Animal sample collection service, Assistance with minor surgery, Animal tattooing service.

Access to CLAR facilities is restricted to authorized investigators with CLAR and IACUC approval. No individuals may enter the facilities without this CLAR/IACUC authorization. Since its inception, the Center for Laboratory Animal Resources (CLAR) has centralized most research and teaching animal care for the Atlanta University Center consortium. Our purpose is to provide total animal care services as needed to all academic and/or research faculty and staff affiliated with any one of the member institutions of the Atlanta University Center (AUC).

Proper citation: MSM Center of Laboratory Animal Resources (RRID:SCR_009935) Copy   

•   Source: SciCrunch Registry

http://msm.eagle-i.net/i/0000012f-7421-42f6-38fa-ed3d80000000

Core facility that provides the following services: Gene variations analysis, Genotyping service.

The Human Genotyping Lab assists investigators to apply the genomic technologies to population-based research. The strategic plan is to create a link between basic science, clinical investigation and population-based research by integrating genomic sciences into our research program. The central hypothesis is that health disparities are related in part to ethnicity-specific DNA variants in critical genes that influence the susceptibility to common diseases. Morehouse School of Medicine has a longstanding interest on the studies of ethnic disparities and a longstanding strength on community outreach to underserved minority populations. Accordingly, the major objective of the MSM Human Genome Core Laboratory is to enhance the research capacity on these sample cohorts and upgrade our research to the molecular genetic level based on cutting-edge genomic technologies.

Proper citation: MSM Gene Variation Core Laboratory (RRID:SCR_009930) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c65-0571-fbab-3b8480000000

Core facility that provides the following services: Microscope access service, Imaging experimental design consultation service, Confocal microscopy service, Microscopy training service, Scanning electron microscopy sample preparation service, Sputter coating access service, Scanning electron microscope access service. The Cell & Developmental Biology (CDB) Microscopy Core is a full-service facility serving the entire University of Pennsylvania community. Our aim is to provide personalized assistance on all aspects of imaging, from tips on sample preparation to training on one of our microscopes to processing and analysis of image data. Our facility currently houses five confocal and three widefield light microscopes, a scanning electron microscope, and several computers dedicated to image processing and analysis.

Proper citation: Penn Cell and Developmental Biology Microscopy Core (RRID:SCR_010004) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-9a9a-cba0-9cd7-d7e280000000

Core facility that provides the following services: NMR spectrometer access, NMR spectrometer training, NMR spectroscopy service, Consultation service for NMR experimental design. Penn Chemistry NMR Facility provides researchers in the Chemistry and Materials Science and Engineering department access to state-of-the-art instrumentation for high resolution NMR spectroscopy. The Facility provides users extensive training to use spectrometers without supervision and expert advice/consultation on advanced applications of NMR spectroscopy to solve research problems. At present, the Facility operates ten high resolution NMR spectrometers (300-600 MHz) of varying capabilities located in the Chemistry building at the corner of 34th and Spruce street, Philadelphia, PA. Penn Chemistry NMR Facility provides limited solution NMR services (data acquisition and spectrum/structure analysis) to other departments/centers of University of Pennsylvania based on hourly charges. However, these services will be limited to the availability of instrument time and personnel. NMR Facility accepts service samples from outside academic and industrial customers based on per hour charges.

Proper citation: Penn Chemistry NMR Facility (RRID:SCR_010005) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7ce8-c10b-fbab-3b8480000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1,2023. Core facility that provides the following services: Flow cytometry analysis service, Cell sorting and analysis service, Flow cytometer analyzer access, Introductory flow cytometry training, Advanced and customized flow cytometry training, Flow cytometry consultation service, FACSAria training, Flow cytometry data analysis, BSL2+ biohazardous human cell sorting, BSL2+ murine biohazardous cell sorting, BSL2+ murine cell sorting access, Non-infectious cell sorting access. The Flow Cytometry and Cell Sorting Resource Laboratory is currently recognized as one of the largest and most comprehensive flow cytometry laboratories in the US. In 2010 it was designated a laboratory of exceptional merit by the National Cancer Institute. Using state-of-the-art technology, the resource provides a broad array of, instrumentation, support, education and consultation to the research community at the University of Pennsylvania. A wide variety of cell sorting applications are supported, from high-speed multicolor (up to 14 colors) cell sorting to low-speed, large nozzle, improved viability sorting. Additionally, a wide variety of cell analysis services (up to 20 parameters) are offered, from traditional analog, easier to use tabletop analyzers to many-laser, many-color, high-speed, fully-digital modern instrumentation. Currently the facility offers 6 cell sorters and 19 analytical instruments. A very active training and consultation program is in place to support these activities. The Scientific Director, Dr. Jonni Moore, and the Technical Director, each have over 25 years experience in the field of cytomics. Researchers at the University of Pennsylvania are increasingly engaged in research projects that require 8-plus-parameter cell sorting of infectious cells and primary human tissues. Investigators using the Flow Cytometry and Cell Sorting Shared Resource have access to virtually any type of cytometric services required for a vast array of applications.

Proper citation: Penn Flow Cytometry and Cell Sorting Resource Laboratory (RRID:SCR_010011) Copy   

•   Source: SciCrunch Registry