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http://www.neurodiscovery.harvard.edu/resources/atrc.html
Core facility that provides provides state-of-the-art molecular pathology resources to the Harvard community including laser capture microscopy, DNA/RNA/miRNA quality/expression analysis, Luminex FlexMap 3D multiplex bead cytometry, and real-time PCR. The ATRC is a fee-for-use facility. For NeuroDiscovery members, the first 10 hours of training, consultation and instrument use is free. This initial period is intended to provide a first time user with preliminary data/proof of concept regarding their project, and is generally sufficient when investigators work under the aegis of ATRC staff. Thereafter, the base fee varies depending on activity and the extent of your proposed work. Project-based charge-back agreements for large projects can be negotiated with the ATRC Director, Dr. Charles Vanderburg. Although priority is given to NeuroDiscovery members investigating neurodegenerative diseases and the CNS, the facility is also available to any academic investigators within the Harvard medical community and the greater-Boston research community. Under special arrangements the facility may also be made available to the commercial sector. Please contact ATRC Director, Dr. Charles Vanderburg, for details.
Proper citation: HNDC Advanced Tissue Resource Center (RRID:SCR_012670) Copy
http://bioinformatics.hms.harvard.edu/
Core facility that offers consultations on basic questions in research computing, bioinformatics and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise. Core has experience in large-scale data management, database design and software development. Staff members can provide assistance in quality assurance and analysis of gene expression arrays, genome-wide SNP arrays, CNV studies and different aspects of second-generation sequencing technologies such as ChIP-seq, RNA-Seq or resequencing efforts. Services also include provision of external information generated from public database, data curation and assistance on choosing the right data format and annotation standard to ensure best practices in data management and submission are being maintained.
Proper citation: Harvard Chan Bioinformatics Core (RRID:SCR_012655) Copy
http://harvard.eagle-i.net/i/0000013c-fd63-dfbb-ea7a-a3a980000000
Core facility that provides the following services: Circulating Tumor Cell analysis, Circulating Tumor Cell Purification. The Circulating Tumor Cell Core Facility uses immunomagnetic technology developed by Veridex, LLC (Raritan, NJ) to isolate rare tumor cells from whole blood. Isolated tumor cells can then be counted or used for downstream analysis such as molecular studies or flow cytometry.
Proper citation: BWH Circulating Tumor Cell Core (RRID:SCR_008258) Copy
http://harvard.eagle-i.net/i/00000137-e19e-59a0-d807-77a880000000
Microscopists at Weld Hill will find a range of tools from the simple hand lens to the confocal microscope for 3-D reconstructions.
Proper citation: Arnold Arboretum of Harvard University: Weld Hill Microscopy Lab (RRID:SCR_004485) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-c61a-a13e-b341-4bb480000000
Core facility that provides the following services: Energy Expenditure Assessment, Body Composition Assessment, Physical Activity Assessment. This component of the core utilizes existing institutional resources for measurement of energy balance and provides personnel support that permit assessment of research in energy balance and nutrition assessment.
Proper citation: Vanderbilt Energy Balance Core Laboratory (RRID:SCR_006665) Copy
http://dartmouth.eagle-i.net/i/0000012a-24fd-6cc0-d8a1-249280000000
Core facility that provides the following services: 7500 fast Q-PCR service, MALDI MS service, Agilent 2100 bioanalyzer service, NanoDrop 1000 service.
Proper citation: Dartmouth Shared Instruments Core Laboratory (RRID:SCR_006415) Copy
http://harvard.eagle-i.net/i/0000012c-60c2-395c-c437-ff0b80000000
Core facility that provides the following services: Cell immortalization through retroviral or lentiviral vectors service, Microscopy training, User-based microscopy service.
Proper citation: BWH Cell Culture and Microscopy Core (RRID:SCR_005562) Copy
http://howard.eagle-i.net/i/00000134-aa06-dbc4-bf4c-ca4080000000
Core facility that provides the following services: Flow cytometry equipment and software access, FACS machine training, FACS data analysis, FACS analysis and population isolation, FACS assay consultation. The goals of this Core Facility are to provide flow cytometry services for Howard University?s research investigators, and develop new applications.
Proper citation: Howard Flow Cytometry Core (RRID:SCR_008506) Copy
https://www.baderc.org/cores/metaboliccore/
Core in BADERC that provides services in consultation and teaching, use of DEXA scanner for determination of body fat and/or bone density, and use of Coulter Counter to measure cell number and cell size distribution.
Proper citation: Boston Area Diabetes Endocrinology Research Center Metabolic Physiology and Energy Balance Core Facility (RRID:SCR_008293) Copy
http://cdrewu.eagle-i.net/i/00000135-20a3-3d3f-f836-7d1b80000000
The AXIS Biomedical Informatics function is dedicated to providing investigators at Charles Drew University (CDU) with state-of-the-art informatics solutions for their research projects. AXIS Biomedical Informatics comprises a multi-disciplinary team of researchers with backgrounds and interest in clinical medicine, biomedical informatics, medical geography and geographical information systems, computer science, sociotechnical theories and qualitative methods.
Proper citation: CDU AXIS Biomedical Informatics function (RRID:SCR_009699) Copy
http://ccny-cuny.eagle-i.net/i/00000137-568a-3b40-bb24-040880000000
LSR II A State-of-the-Art RCMI Flow Cytometry Core is located in MR613 with full time technical support, provided by the Flow Technician Mr. Jeffrey Walker. Mr. Walker is BD trained and certified in both analysis and sorting and has extensive experience in sorting both lymphocytes and larger epithelial cells, as well as with specialized applications including cell cycle analysis and calcium flux. Mr. Walker provides training for regular users wishing to perform independent analysis, and is responsible for all sorting.
Proper citation: CCNY Fluorescence Activated Cell Sorting (RRID:SCR_009696) Copy
http://cau.eagle-i.net/i/00000135-abf1-2607-ecf8-187780000000
CCRTD houses several major instruments to support structural studies of biological molecules, cells, modern cell, and molecular visualization applications. We have an Inverted Digitized Microscope (Zeiss) of general use, plus an advanced Fluorescence-enabled Inverted Digitized Microscope with Z-stacking and Live Cell Imaging modules (Zeiss). For advanced applications including In Situ Hybridization (ISH) and Immunohistochemistry (IHC), in addition to Zeiss microscope above we offer Confocal Fluorescent Microscope (Nikon). The latter is currently undergoing a major upgrade of computer system, software, and optics including addition of lasers.
Proper citation: CAU CCRTD-Structural Biology (RRID:SCR_009694) Copy
http://cau.eagle-i.net/i/00000135-abe7-77c7-ecf8-187780000000
CCRTD Core Facilities house major equipment for DNA and RNA-based applications. We offer polymerase chain reaction ( PCR ) instruments including Real-Time PCR machine (I-Cycle, Bio-Rad), Liquid Scintillation Counter (Beckman Coulter), Lyophilizer and Freeze-Dryer for biological samples, Cell Porator, high-speed and ultra-high-speed Centrifuges, ultra-sensitive Balances, and other supporting equipment. DNA and RNA quantification can be carried out on Spectrophotometers, both single-cuvette (DU650, Beckman Coulter) and 96-well plate based. DNA and RNA can be visualized, digitized, and quantified using Gel Documentation system (Bio-Rad) or Multi-Mode Imager Typhoon 9410, in fluorescent, luminescent, UV, or visible wavelengths; time-resolved fluorescence option is available on BioTek Plate Imager. For X-Ray imaging, we maintain an Automated X-Ray processor and Dark Room; radioisotope imaging is also supported on Typhoon 9410.
Proper citation: CAU CCRTD-Molecular Biology (RRID:SCR_009692) Copy
http://harvard.eagle-i.net/i/0000013a-8f55-ae5a-0802-e06e80000000
Core facility that provides the following services: Mouse Long Bone Scans, Mouse Vertebrae Scans. The Harvard School of Dental Medicine under the direction of The Office of Research operates a core facility composed of two micro CT machines.
Proper citation: HSDM Micro CT Core (RRID:SCR_009693) Copy
http://harvard.eagle-i.net/i/0000012d-56f2-62b7-2162-17a280000000
Core facility that provides the following services: Ultrasound/sonography access service. Ultrasound, which is also known as sonography, is a painless, non-invasive imaging technique that lets us look inside your child''s body without the use of radiation. It uses high-frequency sound waves to create pictures of organs, bones, tissues and blood vessels.
Proper citation: CHB Ultrasound (RRID:SCR_009608) Copy
http://eagle-i.itmat.upenn.edu/i/00000139-02ae-1aca-eb5b-b63c80000000
Core facility that provides the following services: Flow cytometer access, Non-infectious cell sorting, BSL2 biohazardous cell sorting, FlowJo workstation access, Flow cytometry online scheduling service, Sample processing and flow cytometry analysis service, Functional flow cytometry assay service, Cytometric Bead Array service, Flow cytometry data analysis service, Flow cytometer training, Flow cytometry consultation service. The Research Flow Cytometry Core Laboratory of the Children''s Hospital of Philadelphia Research Institute is located on the 12th floor of the Leonard and Madlyn Abramson Pediatric Research Center in room 1207. The laboratory offers state of the art instrumentation and professional technical assistance for performing flow cytometry analyses. We focus on providing services to members of the research community of The Children''s Hospital of Philadelphia and the University of Pennsylvania but users from outside the campus are welcome to our lab. The facility is equipped with three analyzers (LSRFortessa, Accuri C6 and FACSCalibur) and one cell sorter (MoFlo XDP). The analyzers are available 24 hours a day to users carrying a CHOP ID. Users not affiliated with CHOP may access the facility during business hours. Cell sorting services are offered on a fee-for-service basis. The core lab also offers full-service flow cytometry testing, including sample processing and immunophenotyping of blood samples from clinical studies as well as functional flow cytometry assays. The core is under the direction of Dr. Florin Tuluc and the daily activities in the lab are supervised by Eric Riedel., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CHOP Flow Cytometry Core Laboratory (RRID:SCR_009726) Copy
http://eagle-i.itmat.upenn.edu/i/00000142-47d2-2012-91c7-0c6080000000
The Clinical and Translational Research Center (CTRC) offers ophthalmological testing services for children. The Ophthalmology Core at CHOP?s CTRC was established t**provide clinical and translational research services in ophthalmology for the assessment of visual function and structure. Services provided include: * Eye exams (includes visual, recognition and grating acuity; anterior segment, fundus exam, refraction) **Contrast sensitivity **Color vision testing * Optical coherence tomography (OCT) tests of the: **Anterior segment **Posterior segment ? optic nerve **Posterior segment ? retin A* Visual field measures: **Using Humphrey **Using Goldman * Full field sensitivity testing * Electroretinography * Visual evoked potential * Fundus photography * Ocular ultrasound * Professional interpretation of all tests is als**available
Proper citation: CHOP CTRC Ophthalmology Core (RRID:SCR_009724) Copy
http://eagle-i.itmat.upenn.edu/i/0000013a-bc4e-ecdd-d69a-d90d80000000
Core facility that provides the following services: Clinical trials consultation service, Document storage service, Investigational new drug or investigational device exemption application support service, Institutional Review Board submission service, Additional regulatory submissions support service, Protocol development service, Human subject recruitment support service, Study feasibility service, Study placement service. The Clinical Trials Office (CTO) at The Children''s Hospital of Philadelphia is a centralized office that provides resources and assistance to clinical research investigators, enabling them to carry out clinical research in a manner consistent with the Hospital''s goals ? excellent patient care, top-quality education, and innovative research. The CTO has expertise in implementing, conducting, and monitoring clinical trials and provides a variety of services that benefit both novice and experienced clinical researchers. The CTO is designed to ensure the excellence and compliance of an investigator''s clinical research trial. The Children''s Hospital of Philadelphia established the CTO in 1999 as part of the institution''s emphasis on clinical research. Since then, the CTO has experienced rapid growth. The CTO advances the quality and quantity of clinical research at Children''s Hospital and its associated network. Specifically, the CTO supports research at the Hospital by developing and completing submissions to the Hospital''s Institutional Review Board; assisting in the preparation of Investigational New Drug and Investigational Device exemption application submissions to the Federal Drug Administration; conducting clinical research studies under the guidance of principal investigators; and developing budgets and providing research training for investigators, study coordinators, and administrative staff. The CTO staff works in partnership with investigators to ensure the protection of human subjects in accordance with Good Clinical Practice, federal, state and/or local regulations and the requirements of the study sponsor.
Proper citation: CHOP Clinical Trials Office (RRID:SCR_009725) Copy
http://eagle-i.itmat.upenn.edu/i/00000142-3843-baeb-91c7-0c6080000000
The Nutrition Assessment Unit of the Nutrition Core is a state-of-the-art facility for the assessment of growth and body dimensions, body composition (the amount of muscle, fat and bone in the body), energy expenditure, bone density, and muscle strength. The Unit has two locations and four experienced technicians for performing research assessments.
Proper citation: CHOP CTRC Nutrition Core Nutrition Assessment (RRID:SCR_009723) Copy
http://cau.eagle-i.net/i/00000135-abef-4d3d-ecf8-187780000000
We are equipped for proteomics research including Cell Fractionation on one floor and tabletop Ultracentrifuges (Beckman Coulter) , Fast Protein Liquid Chromatography (FPLC), Two-Dimensional Protein Electrophoresis (Protean II, Biorad), and Gel Documentation Systems (one Bio-Rad and one Fuji Medical). Protein quantification can be done using UV-Vis spectrophotometry ( DU650, Beckman Coulter) or multimode Plate Spectrophotometers in both 96-well and 384-well micro well plate formats. Protein gels can also be visualized, digitized, and documented on Multi-Mode Imager Typhoon 9410.
Proper citation: CAU CCRTD-Proteomics (RRID:SCR_009687) Copy
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