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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SRMAtlas
 
Resource Report
Resource Website
1+ mentions
SRMAtlas (RRID:SCR_016996) SRM Atlas, SRMatlas data or information resource, database, atlas Resource of targeted proteomics assays to detect and quantify proteins in complex proteome digests by mass spectrometry. Used to quantify the complete human proteome. collection, proteomic, assay, detect, quantify, protein, mass, spectrometry, peptide American Recovery and Reinvestment Act ;
NHGRI RC2 HG005805;
NIGMS R01 GM087221;
NCRR S10 RR027584;
NIGMS P50 GM076547;
Luxembourg Centre for Systems Biomedicine University Luxembourg ;
European Research Council ;
Swiss National Science Foundation
PMID:27453469 Publicly available, Registration required SCR_016996 2026-02-16 09:49:08 3
Integrative Modeling Platform
 
Resource Report
Resource Website
50+ mentions
Integrative Modeling Platform (RRID:SCR_002982) IMP software resource, software toolkit An open source C++ and Python toolbox for solving complex modeling problems, and a number of applications for tackling some common problems in a user-friendly way. Its broad goal is to contribute to a comprehensive structural characterization of biomolecules ranging in size and complexity from small peptides to large macromolecular assemblies, by integrating data from diverse biochemical and biophysical experiments. It can also be used from the Chimera molecular modeling system, or via one of several web applications. integrative modeling, structure determination, hybrid modeling, macromolecular assembly, c++, python, peptide, biomolecule, model, structural characterization, structure is related to: UCSF Chimera
has parent organization: University of California at San Francisco; California; USA
NIGMS R01 GM083960 PMID:22272186 GNU Lesser General Public License, v2.1 or later, Acknowledgement requested, GNU General Public License SciRes_000187 SCR_002982 IMP - the Integrative Modeling Platform, Integrative Modeling Platform (IMP), IMP the Integrative Modeling Platform 2026-02-16 09:45:58 54
Subcellular Location Image Finder
 
Resource Report
Resource Website
1+ mentions
Subcellular Location Image Finder (RRID:SCR_006723) SLIF data or information resource, database, image SLIF finds fluorescence microscope images in on-line journal articles, and indexes them according to cell line, proteins visualized, and resolution. Images can be accessed via the SLIF Web database. SLIF takes on-line papers and scans them for figures that contain fluorescence microscope images (FMIs). Figures typically contain multiple FMIs, to SLIF must segment these images into individual FMIs. When the FMI images are extracted, annotations for the images (for instance, names of proteins and cell-lines) are also extracted from the accompanying caption text. Protein annotation are also used to link to external databases, such as the Gene Ontology DB. The more detailed process includes: segmentation of images into panels; panel classification, to find FMIs; segmentation of the caption, to find which portions of the caption apply to which panels; text-based entity extraction; matching of extracted entities to database entries; extraction of panel labels from text and figures; and alignment of the text segments to the panels. Extracted FMIs are processed to find subcellular location features (SLFs), and the resulting analyzed, annotated figures are stored in a database, which is accessible via SQL queries. fluorescence, annotation, cell, journal, microscope, protein, subcellular, image, cell line, fluorescence microscope, information retrieval, data mining is listed by: Biositemaps
has parent organization: Carnegie Mellon University; Pennsylvania; USA
Commonwealth of Pennsylvania Tobacco Settlement Fund ;
National Center for Integrative Biomedical Informatics ;
NIGMS R01 GM078622;
NIDA U54 DA021519
PMID:17990497 nif-0000-10308 SCR_006723 SLIF - Subcellular Location Image Finder 2026-02-16 09:46:47 1
MCell
 
Resource Report
Resource Website
50+ mentions
MCell (RRID:SCR_007307) software application, software resource, simulation software Software modeling tool for realistic simulation of cellular signaling in complex 3-D subcellular microenvironment in and around living cells. Program that uses spatially realistic 3D cellular models and specialized Monte Carlo algorithms to simulate movements and reactions of molecules within and between cells. Monte Carlo, simulator, cellular, microphysiology, living, cell, BRAIN Initiative is recommended by: BRAIN Initiative
is related to: CellOrganizer
NIGMS P41 GM103712 Free, Available for download, Freely available nif-0000-00160 https://github.com/mcellteam/mcell SCR_007307 Monte Carlo simulator of cellular microphysiology 2026-02-16 09:46:56 59
libRoadRunner
 
Resource Report
Resource Website
10+ mentions
libRoadRunner (RRID:SCR_014763) software application, software resource, simulation software Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support. simulation engine, simulation software, road runner, roadrunner, systems biology, synthetic biology is listed by: Debian
is listed by: OMICtools
NIGMS GM081070 DOI:10.1093/bioinformatics/btv363 Open source, Available for download OMICS_09368 https://sources.debian.org/src/libroadrunner-dev/ SCR_014763 2026-02-16 09:48:41 11
NMRbox
 
Resource Report
Resource Website
50+ mentions
NMRbox (RRID:SCR_014827) web application, software resource, software toolkit Computing platform for biomolecular NMR available to not-for-profit or government users. It consists of a virtual machine (VM) provisioned with dozens of widely-used NMR software packages, and is available as a cloud-based Platform-as-a-Service (PaaS) or as a downloadable VM for local execution. Nuclear Magnetic Resonance, nmr, spectra, computing platform, platform, virtual machine, cloud, software toolbox NIGMS P41GM111135 Account required SCR_014827 , Nuclear Magnetic Resonance box, NMRbox.org 2026-02-16 09:48:38 78
eMERGE Network: electronic Medical Records and Genomics
 
Resource Report
Resource Website
1+ mentions
eMERGE Network: electronic Medical Records and Genomics (RRID:SCR_007428) eMERGE data or information resource, topical portal, portal A national consortium formed to develop, disseminate, and apply approaches to research that combine DNA biorepositories with electronic medical record (EMR) systems for large-scale, high-throughput genetic research. The consortium is composed of seven member sites exploring the ability and feasibility of using EMR systems to investigate gene-disease relationships. Themes of bioinformatics, genomic medicine, privacy and community engagement are of particular relevance to eMERGE. The consortium uses data from the EMR clinical systems that represent actual health care events and focuses on ethical issues such as privacy, confidentiality, and interactions with the broader community. human, clinical, dna, alzheimer's disease, genome, genomics, gene, genetic, nervous system disease, nucleotide polymorphism, phenotype, bioinformatics, genomic medicine, privacy, community engagement, emr, electronic medical record is related to: PheKB
is related to: NCBI database of Genotypes and Phenotypes (dbGap)
is related to: PheWAS Catalog
has parent organization: Vanderbilt University; Tennessee; USA
Aging NIGMS ;
NHGRI
Available to the research community nif-0000-00539 SCR_007428 eMERGE Network: electronic Medical Records & Genomics - A consortium of biorepositories linked to electronic medical records data for conducting genomics studies, eMERGE Network: electronic Medical Records Genomics, eMERGE Network: electronic Medical Records & Genomics, eMERGE Network, electronic Medical Records & Genomics, The eMERGE Network: electronic Medical Records & Genomics 2026-02-16 09:46:58 2
SimTKCore
 
Resource Report
Resource Website
SimTKCore (RRID:SCR_008268) SimTKCore software application, software resource, simulation software SimTK Core is one of the two packages that together constitute SimTK, the biosimulation toolkit from the Simbios Center. The other major component of SimTK is OpenMM which is packaged separately. This SimTK Core project collects together all the binaries needed for the various SimTK Core subprojects. These include Simbody, Molmodel, Simmath (including Ipopt), Simmatrix, CPodes, SimTKcommon, and Lapack. See the individual projects for descriptions. SimTK brings together in a robust, convenient, open source form the collection of highly-specialized technologies necessary to building successful physics-based simulations of biological structures. These include: strict adherence to an important set of abstractions and guiding principles, robust, high-performance numerical methods, support for developing and sharing physics-based models, and careful software engineering. Accessible High Performance Computing We believe that a primary concern of simulation scientists is performance, that is, speed of computation. We seek to build valid, approximate models using classical physics in order to achieve reasonable run times for our computational studies, so that we can hope to learn something interesting before retirement. In the choice of SimTK technologies, we are focused on achieving the best possible performance on hardware that most researchers actually have. In today''s practice, that means commodity multiprocessors and small clusters. The difference in performance between the best methods and the do-it-yourself techniques most people use can be astoundingeasily an order of magnitude or more. The growing set of SimTK Core libraries seeks to provide the best implementation of the best-known methods for widely used computations such as: Linear algebra, numerical integration and Monte Carlo sampling, multibody (internal coordinate) dynamics, molecular force field evaluation, nonlinear root finding and optimization. All SimTK Core software is in the form of C++ APIs, is thread-safe, and quietly exploits multiple CPUs when they are present. The resulting pre-built binaries are available for download and immediate use. Audience: Biosimulation application programmers interested in including robust, high-performance physics-based simulation in their domain-specific applications. computational algorithm, high-performance, linear algebra, numerical integration, numerical method, optimization, monte carlo sampling, multibody dynamics, molecular force field evaluation, nonlinear root finding, optimizing, cpodes, simbody, ipopt, molmodel, mit license, linux, mac os x, windows is listed by: Biositemaps
has parent organization: Stanford University; Stanford; California
has parent organization: Simtk.org
NIGMS U54 GM072970 PMID:20107615 nif-0000-23310 SCR_008268 2026-02-16 09:47:08 0
SerialEM
 
Resource Report
Resource Website
100+ mentions
SerialEM (RRID:SCR_017293) data acquisition software, software application, data processing software, software resource Software tool for automated EM data acquisition. Used for efficient tilt series acquisition and interface for image capture, display, and storage and for control of some aspects of microscope function. automated, data, acquisition, tilt, image, capture, display, storage, microscope NCRR RR00592;
NIGMS P01 GM61306
PMID:16182563 Restricted SCR_017293 2026-02-16 09:49:12 213
PhyDyn
 
Resource Report
Resource Website
10+ mentions
PhyDyn (RRID:SCR_018544) software application, software resource, simulation software Sofware package for performing Bayesian phylogenetic inference under models that deal with structured populations with complex population dynamics. Enables simultaneous estimation of epidemiological parameters and pathogen phylogenies. Epidemiological modelling in BEAST. Bayesian phylogenetic inference, epidemiological modelling, epidemiological parameter estimation, pathogen phylogeny estimation is related to: BEAST2
is related to: BEAST
NIGMS U01 GM110749;
MRC Centre for Global Infectious Disease Analysis
PMID:30422979 Free, Available for download, Freely available SCR_018544 2026-02-16 09:49:31 10
LinDA
 
Resource Report
Resource Website
1+ mentions
LinDA (RRID:SCR_025966) software application, data processing software, data analysis software, source code, software resource Software linear models for differential abundance analysis of microbiome compositional data. Used to tackle compositional effects in differential abundance analysis. It fits linear regression models on centered log2-ratio transformed data, identifies bias term due to transformation and compositional effect, and corrects bias using mode of regression coefficients. It could fit mixed-effect models. differential abundance analysis, microbiome compositional data, differential abundance analysis, NIGMS R01GM144351;
NSF ;
Mayo Clinic Center for Individualized Medicine
PMID:35421994 SCR_025966 Linear models for differential abundance analysis of microbiome compositional data (LinDA), Linear models for differential abundance analysis of microbiome compositional data 2026-02-16 09:51:03 1
Hippocampal Slice Wave Animations
 
Resource Report
Resource Website
Hippocampal Slice Wave Animations (RRID:SCR_008372) software application, data or information resource, topical portal, resource, data processing software, software resource, simulation software, animation software, portal, data visualization software THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 29, 2013. Supplemental data for the paper Changes in mitochondrial function resulting from synaptic activity in the rat hippocampal slice, by Vytautas P. Bindokas, Chong C. Lee, William F. Colmers, and Richard J. Miller that appears in the Journal of Neuroscience June 15, 1998. You can view digital movies of changes in fluorescence intensity by clicking on the title of interest. animation, hippocampal, hippocampus, mitochondrial, movie, neuroscience, rat, slice, wave MRC of Canada MT10520;
NIDA DA02575;
NIDA DA02121;
NIMH MH40165;
NIDDK DK42086;
NIDDK DK44840;
NINDS NS-33502;
NIGMS 5T32GM07151-22;
NICHD HD07009
PMID:9614233 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25609 SCR_008372 GIF Animations 2026-02-17 10:01:07 0
MODELLER
 
Resource Report
Resource Website
5000+ mentions
MODELLER (RRID:SCR_008395) software application, data or information resource, topical portal, software resource, portal, simulation software Software tool as Program for Comparative Protein Structure Modelling by Satisfaction of Spatial Restraints. Used for homology or comparative modeling of protein three dimensional structures. User provides alignment of sequence to be modeled with known related structures and MODELLER automatically calculates model containing all non hydrogen atoms. comparative, protein, structure, modelling, satisfaction, spatial, restrain, homology, 3D, alignment, sequence, hydrogen, atom, cluster is listed by: SoftCite
has parent organization: University of California at San Francisco; California; USA
Sandler Family Supporting Foundation ;
NIGMS R01 GM54762;
NIGMS P01 GM71790;
NIH P01 A135707;
NIGMS U54 GM62529;
IBM ;
Intel
Restricted nif-0000-30054 SCR_008395 2026-02-17 10:01:21 5736
Motif Mutation Analysis for Regulatory Genomic Elements
 
Resource Report
Resource Website
500+ mentions
Motif Mutation Analysis for Regulatory Genomic Elements (RRID:SCR_021902) MMARGE software application, data processing software, data analysis software, software resource, software toolkit Software package that integrates genome wide genetic variation with epigenetic data to identify collaborative transcription factor pairs. Optimized to work with chromatin accessibility assays such as ATAC-seq or DNase I hypersensitivity, as well as transcription factor binding data collected by ChIP-seq. Used to identify combinations of cell type specific transcription factors while simultaneously interpreting functional effects of non-coding genetic variation. genome wide genetic variation, epigenetic data, identify collaborative transcription factor pairs, interpreting functional effects, non-coding genetic variation NCI CA173903;
NIGMS GM085764;
NIDDK DK091183;
NHLBI R00 123485
PMID:29893919 Free, Available for download, Freely available SCR_021902 2026-02-17 10:04:06 608
3DRefine
 
Resource Report
Resource Website
10+ mentions
3DRefine (RRID:SCR_021883) data access protocol, web service, software resource Interactive web server for efficient protein structure refinement with capability to perform web based statistical and visual analysis. efficient protein structure refinement, statistical and visual analysis NIGMS R01 GM093123 DOI:10.1093/nar/gkw336 Free, Freely available SCR_021883 2026-02-17 10:03:55 20
Seg3D
 
Resource Report
Resource Website
100+ mentions
Seg3D (RRID:SCR_002552) Seg3D data visualization software, software application, image processing software, data processing software, software resource, segmentation software, rendering software, image analysis software A free volume processing segmenting tool that combines a flexible manual interface with powerful image processing and segmentation algorithms. Users can explore and label image volumes using slice windows and 3D volume rendering. analyze, c++, dicom, image display, linux, macos, microsoft, magnetic resonance, nrrd, posix/unix-like, rendering, segmentation, three dimensional display, visualization, volume rendering, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NIGMS 8 P41 GM103545-15 PMID:29083867 Free, Available for download, Freely available nlx_155959 http://www.nitrc.org/projects/seg3d SCR_002552 2026-02-17 09:59:49 101
SOURCE
 
Resource Report
Resource Website
50+ mentions
SOURCE (RRID:SCR_005799) SOURCE data or information resource, production service resource, analysis service resource, database, service resource, data analysis service SOURCE compiles information from several publicly accessible databases, including UniGene, dbEST, UniProt Knowledgebase, GeneMap99, RHdb, GeneCards and LocusLink. GO terms associated with LocusLink entries appear in SOURCE. The mission of SOURCE is to provide a unique scientific resource that pools publicly available data commonly sought after for any clone, GenBank accession number, or gene. SOURCE is specifically designed to facilitate the analysis of large sets of data that biologists can now produce using genome-scale experimental approaches Platform: Online tool genomic, functional annotation, ontology, gene expression, gene, genome, statistical analysis, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: SMD
NIGMS ;
NCI CA85129-04;
NIGMS GM07365
PMID:12519986 Restricted biotools:source, nlx_149287 https://login.stanford.edu/idp/profile/SAML2/Redirect/SSO?execution=e1s1
https://bio.tools/source
SCR_005799 2026-02-17 10:00:39 69
SBO
 
Resource Report
Resource Website
1+ mentions
SBO (RRID:SCR_006753) SBO data or information resource, ontology, database, controlled vocabulary A set of controlled, relational vocabularies of terms commonly used in Systems Biology, and in particular in computational modeling. The ontology consists of seven orthogonal vocabularies defining: the roles of reaction participants (eg. substrate), quantitative parameters (eg. Michaelis constant), a precise classification of mathematical expressions that describe the system (eg. mass action rate law), the modeling framework used (eg. logical framework), and a branch each to describe entity (eg. macromolecule) and interaction (eg. process) types, and a branch to define the different types of metadata that may be present within a model. SBO terms can be used to introduce a layer of semantic information into the standard description of a model, or to annotate the results of biochemical experiments in order to facilitate their efficient reuse. SBO is an Open Biomedical Ontologies (OBO) candidate ontology, and is free for use. A programmatic access to the content of the Systems Biology Ontology is provided by Web Services. systems biology, computational modeling, web service, obo, gold standard is listed by: BioPortal
is related to: BioModels.net
is related to: OBO
has parent organization: European Bioinformatics Institute
NIGMS PMID:17118155 Free, The community can contribute to this resource nlx_66206 SCR_006753 Systems Biology Ontology 2026-02-17 10:01:07 4
iBioSeminars
 
Resource Report
Resource Website
iBioSeminars (RRID:SCR_005848) iBioSeminars narrative resource, video resource, data or information resource, training material iBioSeminars offers: * Free, on-demand lectures: Many universities/colleges have limited access to high profile leaders in biological research. Our goal is to add 15-20 seminars per year, of similar quality to outstanding lectures that are currently in this library. Access, through web streaming or download, is completely free-of-charge. * Targeting a broad audience: iBioSeminars start with an extended introduction, making them accessible to non-specialists and students, and then progress to cover current research. Senior scientists and students can view and enjoy these lectures. * Education: iBioSeminars are being used by undergraduate and graduate teachers to augment their classroom material. We have now added an education component to this web site (including lecture notes, questions/answers and short video clips for teaching). * International communication: iBioSeminars have viewers in 115 countries and they are being internally promoted in several countries as an educational tool and scientific resource. * Goodwill: Lecturers generously donate their time to prepare these lectures. The project, largely funded by HHMI, is a grass roots efforts with time invested by several individuals at UCSF, HHMI and ASCB. biological research, biology, lecture, seminar, education, undergraduate, graduate has parent organization: University of California at San Francisco; California; USA
has parent organization: American Society for Cell Biology
has parent organization: Howard Hughes Medical Institute
NSF ;
NIGMS ;
Howard Hughes Medical Institute
Licensed under a Creative Commons Attribution-NonCommercial-NoDerivs v3 Unported License. nlx_149380 SCR_005848 iBioSeminars - Bringing the World''s Best Biology to You, iBioSeminars - Bringing the Worlds Best Biology to You, iBioSeminars.org 2026-02-17 10:00:40 0
Biomedical Informatics Research Network
 
Resource Report
Resource Website
10+ mentions
Biomedical Informatics Research Network (RRID:SCR_005163) BIRN storage service resource, data or information resource, atlas, database, service resource, software resource, data repository THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 22, 2023. National initiative to advance biomedical research through data sharing and online collaboration that provides data sharing infrastructure, software tools, strategies and advisory services. Groups may choose whether to share data internally or with external audiences. Hardware and data remain under control of individual user groups. dti, fmri, alzheimer's disease, cognitive impairment, collaborative environment, cyberinfrastructure, data sharing, depressive disorder, information technology, infrastructure, memory dysfunction, microarray, mri, neurodegenerative disease, neuroinformatics, neuroimaging, genetics, biomedical material, neurobiology, electrophysiology, collaboration, biomedical, imaging, imaging system, biomedical engineering, brain, health is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is listed by: re3data.org
is listed by: DataCite
has parent organization: University of Southern California; Los Angeles; USA
is parent organization of: Morphometry BIRN
is parent organization of: Knowledge Engineering from Experimental Design
is parent organization of: Mouse Biomedical Informatics Research Network
is parent organization of: NIH Topic Maps - A Topic Database of NIH Funded Grants
is parent organization of: Human Imaging Database
is parent organization of: Function BIRN
is parent organization of: B0 and eddy current correction for DTI
is parent organization of: BrainSuite
is parent organization of: Open Access Series of Imaging Studies
NIH Blueprint for Neuroscience Research ;
NCRR 1U24-RR025736;
NCRR U24-RR021992;
NCRR U24-RR021760;
NCRR 1U24-RR026057-01;
NIGMS U24 GM104203
PMID:21515543
PMID:18348946
PMID:17238407
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00027, r3d100010770 http://www.nitrc.org/projects/birn
https://doi.org/10.17616/R3F02K
http://www.birncommunity.org/, https://neuroscienceblueprint.nih.gov/factSheet/birn.htm SCR_005163 BIRN - The Conduit for Biomedical Research, Biomedical Informatics Research Network - The Conduit for Biomedical Research 2026-02-17 10:00:29 12

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