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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PING
 
Resource Report
Resource Website
50+ mentions
PING (RRID:SCR_005394) PING software resource Software program for probabilistic inference of ChIP-Seq using an empirical Bayes mixture model approach. clustering, sequencing, statistics, visualization, chip-seq, short-read is listed by: OMICtools
has parent organization: Bioconductor
Artistic License v2 OMICS_00513 http://www.nitrc.org/projects/ping SCR_005394 Probabilistic inference for Nucleosome Positioning, PING - Probabilistic inference for Nucleosome Positioning with MNase-based or Sonicated Short-read Data 2026-02-14 02:01:05 83
DMRforPairs
 
Resource Report
Resource Website
1+ mentions
DMRforPairs (RRID:SCR_005702) software resource Software for identifying differentially methylated regions between unique samples using array based methylation profiles. It allows researchers to compare n greater than or equal to 2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishesit from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance. standalone software, mac os x, unix/linux, windows, r, annotation, dna methylation, differential methylation, microarray, report writing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24884391 GNU General Public License, v2 or greater biotools:dmrforpairs, OMICS_04059 https://bio.tools/dmrforpairs SCR_005702 DMR2+, DMRforPairs: identifying Differentially Methylated Regions between unique samples using array based methylation profiles 2026-02-14 02:01:09 4
rMAT
 
Resource Report
Resource Website
10+ mentions
rMAT (RRID:SCR_001583) data processing software, data analysis software, source code, software application, software resource Software package for normalizing and analyzing tiling arrays and ChIP-chip data. It is the R-version of a MAT program. chip-seq, normalize data, tiling array, mat, r is listed by: OMICtools
has parent organization: Bioconductor
PMID:20089513 Free, Available for download, Freely available OMICS_00810 http://www.rglab.org SCR_001583 2026-02-14 02:00:06 16
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 vsn - Variance stabilization and calibration for microarray data 2026-02-14 02:00:09 5
CGHcall
 
Resource Report
Resource Website
10+ mentions
CGHcall (RRID:SCR_001578) data analysis software, software resource, data processing software, software application Software that calls aberrations for array CGH data using a six state mixture model and several biological concepts. It is written in R. cgh data analysis, objective classification, data aberration is listed by: OMICtools
is hosted by: Bioconductor
Free, Available for download, Freely available OMICS_00709 SCR_001578 2026-02-14 02:00:03 30
CNVrd2
 
Resource Report
Resource Website
1+ mentions
CNVrd2 (RRID:SCR_001723) software resource A software package that uses next-generation sequencing data to measure human gene copy number for multiple samples, indentify SNPs tagging copy number variants and detect copy number polymorphic genomic regions. standalone software, illumina, unix/linux, mac os x, windows, r, clustering., copy number variation, coverage, linkage disequilibrium, snp, sequencing is listed by: OMICtools
has parent organization: Bioconductor
PMID:23646200 Free, Available for download, Freely available OMICS_03924 http://www.bioconductor.org/packages/release/bioc/html/CNVrd2.html
https://github.com/hoangtn/CNVrd2
SCR_001723 CNVrd2: a read depth-based method to detect and genotype complex common copy number variants from next generation sequencing data 2026-02-14 02:00:06 5
sSeq
 
Resource Report
Resource Website
10+ mentions
sSeq (RRID:SCR_001719) sSeq software resource Software package to discover the genes that are differentially expressed between two conditions in RNA-seq experiments. Gene expression is measured in counts of transcripts and modeled with the Negative Binomial (NB) distribution using a shrinkage approach for dispersion estimation. The method of moment (MM) estimates for dispersion are shrunk towards an estimated target, which minimizes the average squared difference between the shrinkage estimates and the initial estimates. The exact per-gene probability under the NB model is calculated, and used to test the hypothesis that the expected expression of a gene in two conditions identically follow a NB distribution. rna-seq, differential expression is listed by: OMICtools
has parent organization: Bioconductor
PMID:23589650 Free, Available for download, Freely available OMICS_01962 SCR_001719 sSeq - Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size 2026-02-14 02:00:16 47
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 Free, Available for download, Freely available OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2026-02-14 02:00:16 0
RSVSim
 
Resource Report
Resource Website
10+ mentions
RSVSim (RRID:SCR_001777) software resource A software package for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. SV breakpoints can be placed uniformly accross the whole genome, with a bias towards repeat regions and regions of high homology (for hg19) or at user-supplied coordinates. unix/linux, mac os x, windows, r, sequencing, structural variation is listed by: OMICtools
has parent organization: Bioconductor
PMID:23620362 Free, Available for download, Freely available OMICS_03822 SCR_001777 RSVSim: an R/Bioconductor package for the simulation of structural variations 2026-02-14 02:00:10 16
TCC
 
Resource Report
Resource Website
1+ mentions
TCC (RRID:SCR_001779) TCC software resource An R package that provides a series of functions for differential expression analysis from RNA-seq count data using robust normalization strategy (called DEGES). The basic idea of DEGES is that potential differentially expressed genes or transcripts (DEGs) among compared samples should be removed before data normalization to obtain a well-ranked gene list where true DEGs are top-ranked and non-DEGs are bottom ranked. This can be done by performing a multi-step normalization strategy (called DEGES for DEG elimination strategy). A major characteristic of TCC is to provide the robust normalization methods for several kinds of count data (two-group with or without replicates, multi-group/multi-factor, and so on) by virtue of the use of combinations of functions in other sophisticated packages (especially edgeR, DESeq, and baySeq). rna-seq, differential expression, high throughput sequencing is listed by: OMICtools
has parent organization: Bioconductor
has parent organization: University of Tokyo; Tokyo; Japan
PMID:23837715 Free, Available for download, Freely available OMICS_01952 SCR_001779 Tag Count Comparison, TCC: Differential expression analysis for tag count data with robust normalization strategies 2026-02-14 02:00:07 9
SamSPECTRAL
 
Resource Report
Resource Website
1+ mentions
SamSPECTRAL (RRID:SCR_001858) software resource Software that identifies cell population in flow cytometry data. It demonstrates significant advantages in proper identification of populations with non-elliptical shapes, low density populations close to dense ones, minor subpopulations of a major population and rare populations. It samples large data such that spectral clustering is possible while preserving density information in edge weights. More specifically, given a matrix of coordinates as input, SamSPECTRAL first builds the communities to sample the data points. Then, it builds a graph and after weighting the edges by conductance computation, the graph is passed to a classic spectral clustering algorithm to find the spectral clusters. The last stage of SamSPECTRAL is to combine the spectral clusters. The resulting connected components estimate biological cell populations in the data sample. software package, mac os x, unix/linux, windows, r, cell biology, clustering, flow cytometry, stem cell, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Cancer, HIV PMID:20667133 Free, Available for download, Freely available OMICS_05638, biotools:samspectral https://bio.tools/samspectral SCR_001858 SamSPECTRAL - Identifies cell population in flow cytometry data 2026-02-14 02:00:13 4
RchyOptimyx
 
Resource Report
Resource Website
1+ mentions
RchyOptimyx (RRID:SCR_001889) software resource Software that constructs a hierarchy of cells using flow cytometry for maximization of an external variable (e.g., a clinical outcome or a cytokine response). software package, mac os x, unix/linux, windows, r, flow cytometry is listed by: OMICtools
has parent organization: Bioconductor
PMID:23044634 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_05637 SCR_001889 RchyOptimyx - Optimyzed Cellular Hierarchies for Flow Cytometry, RchyOptimyx: Optimyzed Cellular Hierarchies for Flow Cytometry 2026-02-14 02:00:14 3
CQN
 
Resource Report
Resource Website
1+ mentions
CQN (RRID:SCR_001786) CQN software resource A normalization tool for RNA-Seq data, implementing the conditional quantile normalization method. rna-seq, differential expression, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:22285995 Free, Available for download, Freely available OMICS_01949, biotools:cqn https://bio.tools/cqn SCR_001786 Conditional Quantile Normalization 2026-02-14 02:00:11 6
SPADE
 
Resource Report
Resource Website
100+ mentions
SPADE (RRID:SCR_001810) data visualization software, data processing software, data analysis software, software application, software resource An analysis and visualization software tool for high dimensional flow cytometry data that organizes cells into hierarchies of related phenotypes. software package, mac os x, unix/linux, windows, r, clustering, flow cytometry, gui, graph, network, visualization is listed by: OMICtools
has parent organization: Bioconductor
is a plug in for: FlowJo
PMID:21964415 Free, Available for download, Freely available OMICS_05639 http://cytospade.org/ http://www.bioconductor.org/packages/release/bioc/html/spade.html SCR_001810 Spanning tree Progression of Density normalized Events, SPADE - An analysis and visualization tool for Flow Cytometry 2026-02-14 02:00:18 275
flowType
 
Resource Report
Resource Website
1+ mentions
flowType (RRID:SCR_001957) software resource Software for phenotyping Flow Cytometry assays using multidimentional expansion of single dimentional partitions. software package, mac os x, unix/linux, windows, r, flow cytometry is listed by: OMICtools
has parent organization: Bioconductor
PMID:22383736 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_05613 SCR_001957 flowType - Phenotyping Flow Cytometry Assays 2026-02-14 02:00:15 9
ADaCGH2
 
Resource Report
Resource Website
ADaCGH2 (RRID:SCR_001981) software resource Software for analysis and plotting of array comparative genomic hybridization (CGH) data. It allows usage of Circular Binary Segementation, wavelet-based smoothing (both as in Liu et al., and HaarSeg as in Ben-Yaacov and Eldar), HMM, BioHMM, GLAD, CGHseg. Most computations are parallelized (either via forking or with clusters, including MPI and sockets clusters) and use ff for storing data. standalone software, mac os x, unix/linux, windows, r, copy number variant, microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24532724 Free, Available for download, Freely available biotools:adacgh2, OMICS_03697 https://bio.tools/adacgh2 SCR_001981 ADaCGH2 - Analysis of big data from aCGH experiments using parallel computing and ff objects 2026-02-14 02:00:12 0
TEQC
 
Resource Report
Resource Website
10+ mentions
TEQC (RRID:SCR_001943) software resource An R/Bioconductor package for quality assessment of target enrichment experiments. This package provides functionalities for assessing and visualizing the quality of the target enrichment process, like specificity and sensitivity of the capture, per-target read coverage and so on. standalone software, unix/linux, mac os x, windows, r, genetics, microarray, quality control, sequencing is listed by: OMICtools
has parent organization: Bioconductor
PMID:21398674 Free, Available for download, Freely available OMICS_03602 SCR_001943 TEQC - Quality control for target capture experiments 2026-02-14 02:00:15 14
flowViz
 
Resource Report
Resource Website
10+ mentions
flowViz (RRID:SCR_002075) software resource Software that provides visualization tools for flow cytometry data. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, infrastructure, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:18245128 Free, Available for download, Freely available OMICS_05615 SCR_002075 flowViz - Visualization for flow cytometry 2026-02-14 02:00:14 30
ShortRead
 
Resource Report
Resource Website
100+ mentions
ShortRead (RRID:SCR_006813) ShortRead software resource Software package for input, quality assessment and exploration of high-throughput sequence data. Used for input, quality assurance, and basic manipulation of `short read'' DNA sequences such as those produced by Solexa, 454, and related technologies, including exible import of common short read data formats. high throughput sequence data, short read, DNA sequences, short read data is listed by: OMICtools
is listed by: Debian
is listed by: SoftCite
has parent organization: Bioconductor
PMID:19654119 Free, Available for download, Freely available OMICS_01076 https://sources.debian.org/src/r-bioc-shortread/ SCR_006813 ShortRead - Classes and methods for high-throughput short-read sequencing data. 2026-02-14 02:01:24 225
RIPSeeker
 
Resource Report
Resource Website
10+ mentions
RIPSeeker (RRID:SCR_006810) RIPSeeker software resource A statistical software package for identifying protein-associated transcripts from RIP-seq experiments. Infer and discriminate RIP peaks from RIP-seq alignments using two-state HMM with negative binomial emission probability. While RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides a suite of bioinformatics tools integrated within this self-contained software package comprehensively addressing issues ranging from post-alignments processing to visualization and annotation. rip-seq is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 OMICS_00569 SCR_006810 RIPSeeker: a statistical package for identifying protein-associated transcripts from RIP-seq experiments 2026-02-14 02:01:13 10

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