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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
T1DBase
 
Resource Report
Resource Website
100+ mentions
T1DBase (RRID:SCR_007959) database, service resource, storage service resource, data repository, data or information resource, resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 26,2019. In October 2016, T1DBase has merged with its sister site ImmunoBase (https://immunobase.org). Documented on March 2020, ImmunoBase ownership has been transferred to Open Targets (https://www.opentargets.org). Results for all studies can be explored using Open Targets Genetics (https://genetics.opentargets.org). Database focused on genetics and genomics of type 1 diabetes susceptibility providing a curated and integrated set of datasets and tools, across multiple species, to support and promote research in this area. The current data scope includes annotated genomic sequences for suspected T1D susceptibility regions; genetic data; microarray data; and global datasets, generally from the literature, that are useful for genetics and systems biology studies. The site also includes software tools for analyzing the data. genetics, beta cell, gene, variant, region, genomics, gene expression, genome-wide association study, data analysis service, bio.tools is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is listed by: NIDDK Information Network (dkNET)
is listed by: Debian
is listed by: bio.tools
is related to: dkCOIN
has parent organization: University of Cambridge; Cambridge; United Kingdom
Type 1 diabetes. Diabetes Wellcome Trust ;
NIDDK ;
Juvenile Diabetes Research Foundation
PMID:20937630 THIS RESOURCE IS NO LONGER IN SERVICE. nif-0000-03531, biotools:t1dbase https://bio.tools/t1dbase SCR_007959 T1DBase - Type 1 Diabetes Database 2026-02-15 09:19:40 145
Hippocampal Slice Wave Animations
 
Resource Report
Resource Website
Hippocampal Slice Wave Animations (RRID:SCR_008372) software application, data visualization software, portal, data processing software, software resource, animation software, simulation software, data or information resource, topical portal, resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 29, 2013. Supplemental data for the paper Changes in mitochondrial function resulting from synaptic activity in the rat hippocampal slice, by Vytautas P. Bindokas, Chong C. Lee, William F. Colmers, and Richard J. Miller that appears in the Journal of Neuroscience June 15, 1998. You can view digital movies of changes in fluorescence intensity by clicking on the title of interest. animation, hippocampal, hippocampus, mitochondrial, movie, neuroscience, rat, slice, wave MRC of Canada MT10520;
NIDA DA02575;
NIDA DA02121;
NIMH MH40165;
NIDDK DK42086;
NIDDK DK44840;
NINDS NS-33502;
NIGMS 5T32GM07151-22;
NICHD HD07009
PMID:9614233 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25609 SCR_008372 GIF Animations 2026-02-15 09:19:30 0
Gene Relationships Across Implicated Loci
 
Resource Report
Resource Website
50+ mentions
Gene Relationships Across Implicated Loci (RRID:SCR_008537) data analysis service, service resource, production service resource, analysis service resource, resource A tool to examine relationships between genes in different disease associated loci. Given several genomic regions or SNPs associated with a particular phenotype or disease, GRAIL looks for similarities in the published scientific text among the associated genes. As input, users can upload either (1) SNPs that have emerged from a genome-wide association study or (2) genomic regions that have emerged from a linkage scan or are associated common or rare copy number variants. SNPs should be listed according to their rs#''s and must be listed in HapMap. Genomic Regions are specified by a user-defined identifier, the chromosome that it is located on, and the start and end base-pair positions for the region. Grail can take two sets of inputs - Query regions and Seed regions. Seed regions are definitely associated SNPs or genomic regions, and Query regions are those regions that the user is attempting to evaluate agains them. In many applications the two sets are identical. Based on textual relationships between genes, GRAIL assigns a p-value to each region suggesting its degree of functional connectivity, and picks the best candidate gene. GRAIL is developed by Soumya Raychaudhuri in the labs of David Altshuler and Mark Daly at the Center for Human Genetic Research of Massachusetts General Hospital and Harvard Medical School, and the Broad Institute. GRAIL is described in manuscript, currently in preparation. software, text mining, genotype, phenotype, snp is listed by: 3DVC
has parent organization: Broad Institute
NIAMS 1K08AR055688-01A1;
NIAMS AR007530;
NHGRI U01HG004171;
NIDDK R01DK083759
PMID:19557189 nif-0000-30627 SCR_008537 GRAIL 2026-02-15 09:19:51 67
National Mouse Metabolic Phenotyping Centers
 
Resource Report
Resource Website
500+ mentions
National Mouse Metabolic Phenotyping Centers (RRID:SCR_008997) MMPC, NIDDKMMPC data or information resource, database, service resource Center mission is to advance medical and biological research by providing the scientific community with standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders. phenotype, phenotyping, metabolism, cardiovascular, gastrointestinal, endocrine, energy, analytic, blood composition, in vivo, hormone, energy balance, eating, exercise, organ function, morphology, physiology, histology, experimental protocol, assay, strain, measurement, animal husbandry, FASEB list is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is used by: Hypothesis Center
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
is related to: dkCOIN
has parent organization: Augusta University; Georgia; USA
has parent organization: Case Western Reserve University; Ohio; USA
has parent organization: University of Cincinnati; Ohio; USA
has parent organization: Vanderbilt University School of Medicine; Tennessee; USA
has parent organization: University of California at Davis; California; USA
has parent organization: University of Massachusetts Medical School; Massachusetts; USA
has parent organization: Yale School of Medicine; Connecticut; USA
is parent organization of: MMPC-Vanderbilt University School of Medicine Animal Health and Welfare Core
is parent organization of: MMPC-Vanderbilt University School of Medicine Analytical Resources Core
is parent organization of: MMPC-University of Michigan Medical School Microbiome Core
is parent organization of: MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core
is parent organization of: MMPC-University of Michigan Medical School Microvascular Complications Core
is parent organization of: MMPC-University of Massachusetts Medical School Cardiovascular Core
is parent organization of: MMPC-Vanderbilt University School of Medicine
is parent organization of: MMPC-University of Michigan Medical School
is parent organization of: MMPC-University of Massachusetts Medical School Humanized Mouse Cell Transplantation and Assessment Core
is parent organization of: MMPC-University of Cincinnati Medical Center Energy Metabolism Food Intake and Body Weight Regulation Core
is parent organization of: MMPC-University of Massachusetts Medical School Islet Core
is parent organization of: MMPC-University of Massachusetts Medical School Metabolism Core
is parent organization of: MMPC-University of Massachusetts Medical School Animal Care Core
is parent organization of: MMPC-University of Cincinnati Medical Center
is parent organization of: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility
is parent organization of: MMPC-University of Massachusetts Medical School Analytical Core
is parent organization of: MMPC-University of California Davis Energy Balance Exercise and Behavior Core
is parent organization of: MMPC-University of Cincinnati Medical Center Lipid Lipoprotein and Glucose Metabolism Core
is parent organization of: MMPC-University of California Davis Administrative Core
is parent organization of: MMPC-University of California Davis Microbiome and Host Response Core
is parent organization of: MMPC-University of Cincinnati Medical Center Cardiovascular and Renal Function Core
is parent organization of: MMPC-University of California Davis Endocrinology and Metabolism Core
is parent organization of: MMPC-University of California Davis
is parent organization of: MMPC-University of California Davis Animal Care Surgery and Pathology Core
is parent organization of: MMPC-University of Michigan Medical School Metabolism Bariatric Surgery and Behavior Core
is parent organization of: MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core
is parent organization of: MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core
has organization facet: MMPC-University of California Davis
has organization facet: MMPC-University of Cincinnati Medical Center
has organization facet: University of Massachusetts Medical School Metabolic Disease Research Center Core Facility
has organization facet: MMPC-University of Michigan Medical School
has organization facet: MMPC-Vanderbilt University School of Medicine
Diabetes, Obesity, Diabetic complication, Metabolic disease, Cardiovascular disease, Nephropathy, Neuropathy, Retinopathy NIDDK U24 DK076174;
NIDDK U24 DK092993;
NIDDK U24 DK059630;
NIDDK U24 DK093000;
NIDDK U24 DK059637;
NIDDK U24 DK059635
Freely available, SCR_015358, nlx_152633 SCR_008997 Mouse Metabolic Phenotyping Centers 2026-02-15 09:19:36 714
Clinical Outcomes Research Initiative
 
Resource Report
Resource Website
1+ mentions
Clinical Outcomes Research Initiative (RRID:SCR_009010) CORI database, software resource, service resource, data or information resource, resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5, 2022. Endoscopic Reporting Software, aggregated and individual research data and tailor-made services aimed to advance the overall practice of endoscopy. It was developed to study outcomes of gastrointestinal (GI) endoscopic procedures in real life settings, using data obtained from the CORI Endoscopic Reporting Software or from other endoscopic reporting software. Practice sites include hospitals, ambulatory care centers, private practices, universities, and Veteran''''s hospitals (VA''''s). The CORI v4 Endoscopic Reporting Software is a specialty Electronic Health Record used to document endoscopic procedures and provide reporting services to your practice. Data from participating providers is also sent to a central data repository to become part of the National Endoscopic Database (NED), which now contains data from over 2.7 million GI procedures. The CORI v4 Endoscopic Reporting Software offers significant benefits for participating practices, providers and patients, as well as for everyone who benefits from CORI''''s research efforts. You may actively participate in research with CORI. If you have ideas for research using the NED, their research team can help you evaluate those ideas, collect and analyze the data. In addition, you may choose to participate in one of the prospective research projects conducted by CORI research staff. clinical, endoscopy, gastroenterology, gastrointestinal, endoscopic, endoscopy reporting software, outcome, report, electronic health record, aggregator is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: Oregon Health and Science University; Oregon; USA
NIDDK THIS RESOURCE IS NO LONGER IN SERVICE nlx_152692 SCR_009010 2026-02-15 09:19:36 6
GeneSpeed- A Database of Unigene Domain Organization
 
Resource Report
Resource Website
GeneSpeed- A Database of Unigene Domain Organization (RRID:SCR_002779) data analysis service, database, service resource, production service resource, data or information resource, analysis service resource, resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. Database and customized tools to study the PFAM protein domain content of the transcriptome for all expressed genes of Homo sapiens, Mus musculus, Drosophila melanogaster, and Caenorhabditis elegans tethered to both a genomics array repository database and a range of external information resources. GeneSpeed has merged information from several existing data sets including the Gene Ontology Consortium, InterPro, Pfam, Unigene, as well as micro-array datasets. GeneSpeed is a database of PFAM domain homology contained within Unigene. Because Unigene is a non-redundant dbEST database, this provides a wide encompassing overview of the domain content of the expressed transcriptome. We have structured the GeneSpeed Database to include a rich toolset allowing the investigator to study all domain homology, no matter how remote. As a result, homology cutoff score decisions are determined by the scientist, not by a computer algorithm. This quality is one of the novel defining features of the GeneSpeed database giving the user complete control of database content. In addition to a domain content toolset, GeneSpeed provides an assortment of links to external databases, a unique and manually curated Transcription Factor Classification list, as well as links to our newly evolving GeneSpeed BetaCell Database. GeneSpeed BetaCell is a micro-array depository combined with custom array analysis tools created with an emphasis around the meta analysis of developmental time series micro-array datasets and their significance in pancreatic beta cells. molecular neuroanatomy resource, drosophila melanogaster, genome, caenorhabditis elegans, c. elegans, genomics, homo sapiens, mus musculus, protein domain, transcriptome is related to: Gene Ontology
is related to: InterPro
is related to: Pfam
is related to: UniGene
has parent organization: University of Colorado Denver; Colorado; USA
NIDDK P30DK57516;
NIDDK DK61248
PMID:17132830 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02887 http://genespeed.uchsc.edu/, http://genespeed.ccf.org SCR_002779 GeneSpeed Database 2026-02-15 09:18:23 0
RNA Abundance Database
 
Resource Report
Resource Website
1+ mentions
RNA Abundance Database (RRID:SCR_002771) RAD database, service resource, storage service resource, data repository, data or information resource, resource THIS RESOURCE IS NO LONGER IN SERVICE, Documented on March 24, 2014. A resource for gene expression studies, storing highly curated MIAME-compliant studies (i.e. experiments) employing a variety of technologies such as filter arrays, 2-channel microarrays, Affymetrix chips, SAGE, MPSS and RT-PCR. Data were available for querying and downloading based on the MGED ontology, publications or genes. Both public and private studies (the latter viewable only by users having appropriate logins and permissions) were available from this website. Specific details on protocols, biomaterials, study designs, etc., are collected through a user-friendly suite of web annotation forms. Software has been developed to generate MAGE-ML documents to enable easy export of studies stored in RAD to any other database accepting data in this format. RAD is part of a more general Genomics Unified Schema (http://gusdb.org), which includes a richly annotated gene index (http://allgenes.org), thus providing a platform that integrates genomic and transcriptomic data from multiple organisms. NOTE: Due to changes in technology and funding, the RAD website is no longer available. RAD as a schema is still very much active and incorporated in the GUS (Genomics Unified Schema) database system used by CBIL (EuPathDB, Beta Cell Genomics) and others. The schema for RAD can be viewed along with the other GUS namespaces through our Schema Browser. gene expression, gene, affymetrix, biomaterial, genomics, microarray, mpss, ontology, rna, rt-pcr, sage, functional genomics, transcript abundance is listed by: OMICtools
is related to: MIAME
is related to: MGED Ontology
is related to: MicroArray and Gene Expression Markup Language
has parent organization: University of Pennsylvania; Philadelphia; USA
NIH ;
NHGRI RO1-HG-01539;
NIDDK U01DK56947;
NHGRI K25-HG-02296;
NHGRI K25-HG-00052
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00133, OMICS_00869, r3d100000017 https://doi.org/10.17616/R3QP4Q SCR_002771 RNA Abundance Database 2026-02-15 09:18:22 4
SNPHunter
 
Resource Report
Resource Website
SNPHunter (RRID:SCR_002968) software application, sequence analysis software, data processing software, software resource, data analysis software, resource A tool for SNP Search and downloading with local management. It also offers flanking sequence downloading and automatic SNP filtering. It requires Windows and .NET Framework. population, genetics, software, management, single nucleotide polymorphism, population genetics, training tools, data acquisition is listed by: 3DVC
has parent organization: Harvard University; Cambridge; United States
NIH ;
NHGRI R01HG002518;
NIDDK R01DK062290;
NIDDK R01DK066401;
NHLBI R01HL073882
DOI:10.1186/1471-2105-6-60 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30137 http://www.hsph.harvard.edu/ppg/software.htm SCR_002968 SNPHunter - dbSNP Search & Management, Program for Population Genetics Software 2026-02-15 09:18:25 0
NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources
 
Resource Report
Resource Website
NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources (RRID:SCR_003074) data or information resource, topical portal, portal, resource THIS RESOURCE IS NO LONGER IN SERVICE, documented May 23, 2017. This website contains resources for obesity researchers including: Obesity Databases, Registries and Information; Obesity Multicenter Clinical Research; Obesity Basic Research Networks; Obesity Reagents; Obesity Services; Obesity Standardization Programs; Obesity Tissues, Cells, Animals; Obesity Useful Tools. diabetes, type 1 diabetes, digestive disease, genetic metabolic disease, gene therapy, hematologic disease, hiv/aids research, immunological disease, kidney disease, liver disease, obesity, pancreas, urological disease, biotechnology, endocrinology, epidemiology, genetics, genomics, molecular hematology, molecular therapy, cystic fibrosis, polycystic kidney disease is related to: Rodent Operant Bucket project
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is parent organization of: CKD Biomarkers Consortium
Type 1 diabetes, Type 2 diabetes, Diabetes NIDDK THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00551 SCR_003074 NIDDKObesity Resources 2026-02-15 09:18:26 0
ToppGene Suite
 
Resource Report
Resource Website
1000+ mentions
ToppGene Suite (RRID:SCR_005726) portal, data analysis service, database, service resource, production service resource, data or information resource, analysis service resource, resource ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis. gene portal, enrichment analysis, functional annotation, gene prioritization, protein interaction, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: NIDDK Information Network (dkNET)
is listed by: GUDMAP Ontology
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: ToppCluster
State of Ohio Computational Medicine Center ODD TECH 04-042;
NIDDK 1U01DK70219;
NIDDK P30DK078392
PMID:19465376 Free for academic use nlx_149183, biotools:toppgene_suite https://bio.tools/toppgene_suite SCR_005726 ToppGene 2026-02-15 09:19:02 1030
Autoimmunity Centers of Excellence
 
Resource Report
Resource Website
Autoimmunity Centers of Excellence (RRID:SCR_006510) ACE portal, research forum portal, data or information resource, topical portal, disease-related portal, resource Nine centers that conduct clinical trials and basic research on new immune-based therapies for autoimmune diseases. This program enhances interactions between scientists and clinicians in order to accelerate the translation of research findings into medical applications. By promoting better coordination and communication, and enabling limited resources to be pooled, ACEs is one of NIAID''''s primary vehicles for both expanding our knowledge and improving our ability to effectively prevent and treat autoimmune diseases. This coordinated approach incorporates key recommendations of the NIH Autoimmune Diseases Research Plan and will ensure progress in identifying new and highly effective therapies for autoimmune diseases. ACEs is advancing the search for effective treatments through: * Diverse Autoimmunity Expertise Medical researchers at ACEs include rheumatologists, neurologists, gastroenterologists, and endocrinologists who are among the elite in their respective fields. * Strong Mechanistic Foundation ACEs augment each clinical trial with extensive basic studies designed to enhance understanding of the mechanisms responsible for tolerance initiation, maintenance, or loss, including the role of cytokines, regulatory T cells, and accessory cells, to name a few. * Streamlined Patient Recruitment The cooperative nature of ACEs helps scientists recruit patients from distinct geographical areas. The rigorous clinical and basic science approach of ACEs helps maintain a high level of treatment and analysis, enabling informative comparisons between patient groups. immune system, infection, clinical trial, clinical, basic research is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
Type 1 diabetes, Diabetes, Autoimmune disease, Systematic lupus erythematosus, Rheumatoid arthritis, Sjogren's syndrome, Multiple sclerosis, Chronic inflammatory bowel disease, Pemphigus vulgaris, Scleroderma NIAID ;
NIDDK ;
NIH Office of Research on Womens Health
nlx_152751 SCR_006510 2026-02-15 09:19:17 0
NIDDK Central Repository
 
Resource Report
Resource Website
50+ mentions
NIDDK Central Repository (RRID:SCR_006542) CDR, NIDDKCDR database, service resource, storage service resource, data repository, data or information resource, biospecimen repository, material storage repository NIDDK Central Repositories are two separate contract funded components that work together to store data and samples from significant, NIDDK funded studies. First component is Biorepository that gathers, stores, and distributes biological samples from studies. Biorepository works with investigators in new and ongoing studies as realtime storage facility for archival samples.Second component is Data Repository that gathers, stores and distributes incremental or finished datasets from NIDDK funded studies Data Repository helps active data coordinating centers prepare databases and incremental datasets for archiving and for carrying out restricted queries of stored databases. Data Repository serves as Data Coordinating Center and website manager for NIDDK Central Repositories website. clinical supply resource, data, clinical, sample sharing, genotyping, genotype, phenotype, genetic analysis, data sharing, genetics, serum, plasma, stool, urine, dna, red blood cell, buffy coat, tissue, immortalized cell line, cell line, data set, digestive organ, kidney, diabetes, kidney disease, digestive disease, genome-wide association study, sequencing, FASEB list uses: DataCite
is used by: NIDDK Information Network (dkNET)
is used by: NIF Data Federation
is used by: NIH Heal Project
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
lists: HEALTHY study
lists: Nonalcoholic Steatohepatitis Clinical Research Network
lists: HALT-C Trial
lists: Type 1 Diabetes Genetics Consortium
lists: TEDDY
lists: Type 1 Diabetes TrialNet
lists: Rare and Atypical Diabetes Network
lists: Diabetes Prevention Program
lists: Diabetes Prevention Program Outcomes Study
lists: Restoring Insulin Secretion Consortium (RISE)
lists: Epidemiology of Diabetes Interventions and Complications
lists: Diabetes Control and Complications Trial
lists: Treatment Options for type 2 Diabetes in Adolescents and Youth
is listed by: One Mind Biospecimen Bank Listing
is listed by: re3data.org
is listed by: Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB)
is listed by: NIDDK Information Network (dkNET)
is related to: NCBI database of Genotypes and Phenotypes (dbGap)
is related to: Peginterferon and Ribavirin for Pediatric Patients with Chronic Hepatitis C
is related to: Chronic Renal Insufficiency Cohort Study
has parent organization: RTI International
NIDDK PMID:23396299
PMID:21959867
PMID:16595012
Restricted nlx_152673, r3d100010377 https://doi.org/10.17616/R3WP48 https://www.niddkrepository.org, SCR_006542 NIDDK Central Repository, National Institute of Diabetes and Digestive and Kidney Diseases Central Repository, NIDDKCentral Repositories 2026-02-15 09:19:18 85
Glomerular Filtration Rate Calculators
 
Resource Report
Resource Website
Glomerular Filtration Rate Calculators (RRID:SCR_006443) GFR Calculators data analysis service, service resource, production service resource, analysis service resource, resource Glomerular Filtration Rate (GFR) calculators to estimate kidney function for adults (MDRD GFR Calculator) and children (Schwartz GFR Calculator). In adults, the recommended equation for estimating glomerular filtration rate (GFR) from serum creatinine is the Modification of Diet in Renal Disease (MDRD) Study equation. The IDMS-traceable version of the MDRD Study equation is used. Currently the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Schwartz equation for use with creatinine methods with calibration traceable to IDMS. Using the original Schwartz equation with a creatinine value from a method with calibration traceable to IDMS will overestimate GFR. adult human, child, glomerular filtration rate, estimate, kidney function, serum creatinine is related to: Creatinine Standardization Program
is related to: NIDDK Information Network (dkNET)
has parent organization: National Kidney Disease Education Program
Chronic kidney disease NIDDK PMID:16908915 nlx_152733 SCR_006443 Glomerular Filtration Rate Calculator, Glomerular Filtration Rate (GFR) Calculator 2026-02-15 09:19:27 0
Creatinine Standardization Program
 
Resource Report
Resource Website
1+ mentions
Creatinine Standardization Program (RRID:SCR_006441) Creatinine Standardization Program data or information resource, experimental protocol, narrative resource, standard specification, international standard specification, resource Standard specification to reduce inter-laboratory variation in creatinine assay calibration and therefore enable more accurate estimates of glomerular filtration rate (eGFR). Created by NKDEP''''s Laboratory Working Group in collaboration with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the European Communities Confederation of Clinical Chemistry (now called the European Federation of Clinical Chemistry and Laboratory Medicine), the effort is part of a larger NKDEP initiative to help health care providers better identify and treat chronic kidney disease in order to prevent or delay kidney failure and improve patient outcomes. Recommendations are intended for the USA and other countries or regions that have largely completed standardization of creatinine calibration to be traceable to an isotope dilution mass spectrometry (IDMS) reference measurement procedure. The program''''s focus is to facilitate the sharing of information to assist in vitro diagnostic manufacturers, clinical laboratories, and others in the laboratory community with calibrating their serum creatinine measurement procedures to be traceable to isotope dilution mass spectrometry (IDMS). The program also supports manufacturers'''' efforts to encourage their customers in the laboratory to coordinate use of standardized creatinine methods with implementation of a revised GFR estimating equation appropriate for use with standardized creatinine methods. Communication resources and other information for various segments of the laboratory community are available in the Creatinine Standardization Recommendations section of the website. Also available is a protocol for calibrating creatinine measurements using whole blood devices. The National Institute for Standards and Technology (NIST) released a standard reference material (SRM 967 Creatinine in Frozen Human Serum) for use in establishing calibrations for routine creatinine measurement procedures. SRM 967 was validated to be commutable with native serum samples for many routine creatinine procedures and is useful to establish or verify traceability to an IDMS reference measurement procedure. Establishing calibrations for serum creatinine methods using SRM 967 not only provides a mechanism for ensuring more accurate measurement of serum creatinine, but also enables more accurate estimates of GFR. For clinical laboratories interested in independently checking the calibration supplied by their creatinine reagent suppliers/manufacturers, periodic measurement of NIST SRM 967 should be considered for inclusion in the lab''''s internal quality assurance program. To learn more about SRM 967, including how to purchase it, visit the NIST website, https://www-s.nist.gov/srmors/quickSearch.cfm creatinine, estimate, glomerular filtration rate, kidney, isotope dilution mass spectrometry, whole blood, calibration, serum, serum creatinine, clinical is related to: Glomerular Filtration Rate Calculators
is related to: NIDDK Information Network (dkNET)
is related to: NIST - National Institute of Standards and Technology
has parent organization: National Kidney Disease Education Program
Chronic kidney disease NIDDK nlx_152736 SCR_006441 2026-02-15 09:19:15 2
Irritable Bowel Syndrome Outcome Study
 
Resource Report
Resource Website
Irritable Bowel Syndrome Outcome Study (RRID:SCR_001504) IBSOS clinical trial, resource Multi-center placebo-controlled randomized clinical trial to assess the short-term and long-term efficacy of cognitive behavior therapy (CBT) for irritable bowel syndrome (IBS) using two treatment delivery systems: self administered CBT and therapist administered CBT. Long term project goals are to develop an effective self-administered behavioral treatment program that can enhance the quality of patient care, improve clinical outcomes, and decrease the economic and personal costs of one of the most prevalent and intractable gastrointestinal disorders. gastrointestinal disorder, cognitive behavior therapy, self-management, self-administered is listed by: NIDDK Information Network (dkNET)
has parent organization: University at Buffalo; New York; USA
Irritable bowel syndrome NIDDK 5U01DK077738-07 PMID:22846389 Free nlx_152839 SCR_001504 2026-02-14 02:07:49 0
Folic Acid for Vascular Outcome Reduction in Transplantation
 
Resource Report
Resource Website
1+ mentions
Folic Acid for Vascular Outcome Reduction in Transplantation (RRID:SCR_001505) FAVORIT clinical trial, resource Multi-center, randomized, double blind controlled clinical trial to determine whether treatment with a standard multivitamin augmented with high doses of folic acid, vitamin B6 and vitamin B12 reduces the rate of cardiovascular disease outcomes in renal transplant recipients relative to participants receiving a similar multivitamin that contains no folic acid. This study hopes to show that by reducing the level of homocysteine in the body, the risk of heart disease is also reduced among kidney transplant patients. multivitamin, folic acid, vitamin b6, vitamin b12, outcome, homocysteine, adult human, middle adult human, late adult human, vitamin, bibliography is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
Cardiovascular disease, Kidney transplant recipient NIDDK U01DK061700 PMID:16923411 Free, Freely available nlx_152827 http://www.cscc.unc.edu/favorit/ http://www.cscc.unc.edu/favorit/favdescrip.htm SCR_001505 Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) 2026-02-14 02:07:18 1
Family Investigation of Nephropathy of Diabetes
 
Resource Report
Resource Website
Family Investigation of Nephropathy of Diabetes (RRID:SCR_001525) FIND, F.I.N.D. clinical trial, resource Multicenter observational study designed to identify genetic determinants of diabetic nephropathy. It is conducted in eleven U.S. clinical centers and a coordinating center, and with four ethnic groups (European Americans, African Americans, Mexican Americans, and American Indians). Two strategies are used to localize susceptibility genes: a family-based linkage study and a case-control study using mapping by admixture linkage disequilibrium (MALD). In the family-based study, probands with diabetic nephropathy are recruited with their parents and selected siblings. Linkage analyses will be conducted to identify chromosomal regions containing genes that influence the development of diabetic nephropathy or related quantitative traits such as serum creatinine concentration, urinary albumin excretion, and plasma glucose concentrations. Regions showing evidence of linkage will be examined further with both genetic linkage and association studies to identify genes that influence diabetic nephropathy or related traits. Two types of MALD studies are being done. One is a case-control study of unrelated individuals of Mexican American heritage in which both cases and controls have diabetes, but only the case has nephropathy. The other is a case-control study of African American patients with nephropathy (cases) and their spouses (controls) unaffected by diabetes and nephropathy; offspring are genotyped when available to provide haplotype data. The specific goals of this program: * Delineate genomic regions associated with the development and progression of renal disease(s) * Evaluate whether there is a genetic link between diabetic nephropathy and diabetic retinopathy * Improve outcomes * Provide protection for people at risk and slow the progression of renal disease * Help establish a resource for genetic studies of kidney disease and diabetic complications by creating a repository of genetic samples and a database * Encourage studies of the genetics of progressive renal disease genetic susceptibility, genetic pathway, renal, kidney, outcome, gene, genetics, european-american, african-american, mexican-american, american-indian, linkage association study, admixture linkage disequilibrium, mapping by admixture linkage disequilibrium, serum creatinine, urinary protein excretion, plasma glucose level, blood pressure, blood lipid level, trait, linkage, adult human, male, female, clinical is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
NIDDK 5R01DK053591 PMID:15642484 Free, Freely available nlx_152825 https://www.niddkrepository.org/studies/find/ SCR_001525 Family Investigation of Nephropathy and Diabetes (F.I.N.D.), Family Investigation of Nephropathy & Diabetes 2026-02-14 02:07:49 0
HALT PKD
 
Resource Report
Resource Website
1+ mentions
HALT PKD (RRID:SCR_001529) HALT PKD, HALT-PKD clinical trial, resource Consortium established to design and implement clinical trials of treatments that might slow the progressive loss of renal function in Polycystic Kidney Disease (PKD). Two multicenter randomized, double-blind, placebo controlled clinical trials are running concurrently to study the efficacy of renin-angiotensin-aldosterone system blockade on the progression of cystic disease (kidney volume) and on the decline in renal function in autosomal dominant polycystic kidney disease (ADPKD). Study A is to study whether intensive ACE-I/ARB blockade decrease the progression of cystic disease compared to ACE-I monotherapy patients with early disease, relatively preserved renal function, and high-normal BP or hypertension. Study B is to study whether intensive ACE-I/ARB blockade as compared to ACE-I monotherapy slow the decline in kidney function, end-stage of renal disease, or death in the setting of standard blood pressure control in hypertensive patients with moderately advanced disease. treatment, renal function, lisinopril, placebo, telmisartan, male, female, adolescent, adult human is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA
Polycystic kidney disease, Autosomal dominant polycystic kidney disease NIDDK 5U01DK062408 Free, Freely available nlx_152832 https://www.niddkrepository.org/studies/halt-pkd/ http://www.pkd.wustl.edu/pkdtn/ SCR_001529 Polycystic Kidney Disease-Treatment Network 2026-02-14 02:07:45 1
Clinical Islet Transplantation Study
 
Resource Report
Resource Website
1+ mentions
Clinical Islet Transplantation Study (RRID:SCR_001515) CIT Study clinical trial, resource Network of centers to conduct studies of islet transplantation in patients with type 1 diabetes to improve the safety and long-term success of methods for transplanting islets. It is the aim of this trial to improve methods of isolating islets, to improve techniques for the administering those transplanted islets; and to develop approaches to minimize the toxic effects of immunosuppressive drugs required for transplantation. islet transplantation, islet, insulin, beta cell, pancreas, autoimmune, clinical is listed by: NIDDK Information Network (dkNET) Type 1 diabetes, Diabetes NIDDK U01DK070431 Free, Freely available nlx_152840 SCR_001515 Clinical Islet Transplantation Trial, Islet Transplantation Trials for Type 1 Diabetes 2026-02-14 02:07:27 4
RiVuR
 
Resource Report
Resource Website
1+ mentions
RiVuR (RRID:SCR_001539) RIVUR clinical trial, resource Multicenter, randomized, double-blind, placebo-controlled trial is designed to determine whether daily antimicrobial prophylaxis is superior to placebo in preventing recurrence of urinary tract infection (UTI) in children with vesicoureteral reflux (VUR). The basic eligibility criteria are: (1) age at randomization of at least 2 months, but less than 6 years, (2) a diagnosed first febrile or symptomatic UTI within 42 days prior to randomization that was appropriately treated, and (3) presence of Grade I-IV VUR based on voiding cystourethrogram (VCUG). Patients will be randomly assigned to treatment for 2 years with daily antimicrobial prophylaxis (trimethoprim-sulfamethoxazole) or placebo. The study is designed to recruit 600 children (approximately 300 in each treatment group) over an 18-24 month period. The primary endpoint is recurrence of UTI. In addition, patients will be evaluated for secondary endpoints related to renal scarring and antimicrobial resistance. Scarring will be determined based on renal scintigraphy by 99mTc dimercaptosuccinic (DMSA) scan. Quality of life, compliance, safety parameters, utilization of health resources, and change in VUR will be assessed periodically throughout the study. child, antimicrobial prophylaxis, placebo, antibiotic, renal scarring, pediatric, trimethoprim-sulfamethoxazole, intervention, kidney, antibiotic resistance, young human, infant, bibliography, clinical, trimethoprim, sulfamethoxazole is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
Vesico-ureteral reflux, Urinary tract infection NIDDK PMID:19570724
PMID:19018048
PMID:18076937
PMID:19018047
PMID:19086141
Free, Freely available nlx_152848 http://www.cscc.unc.edu/rivur/ SCR_001539 Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR), Randomized Intervention for Children with Vesicoureteral Reflux, Randomized Intervention for Vesicoureteral Reflux 2026-02-14 02:07:49 1

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