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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GreenPhylDB
 
Resource Report
Resource Website
10+ mentions
GreenPhylDB (RRID:SCR_002834) GreenPhylDB data or information resource, production service resource, analysis service resource, database, service resource, data analysis service A database designed for plant comparative and functional genomics based on complete genomes. It comprises complete proteome sequences from the major phylum of plant evolution. The clustering of these proteomes was performed to define a consistent and extensive set of homeomorphic plant families. Based on this, lists of gene families such as plant or species specific families and several tools are provided to facilitate comparative genomics within plant genomes. The analyses follow two main steps: gene family clustering and phylogenomic analysis of the generated families. Once a group of sequences (cluster) is validated, phylogenetic analyses are performed to predict homolog relationships such as orthologs and ultraparalogs. comparative genomics, genome, functional genomics, genomics, gene family, homolog, bio.tools uses: Gene Ontology
is listed by: bio.tools
is listed by: Debian
has parent organization: CIRAD
PMID:20864446 Free, Freely available, Available for download biotools:greenphyldb, nif-0000-02928 http://greenphyl.cirad.fr
http://www.greenphyl.org/v3/
https://bio.tools/greenphyldb
SCR_002834 2026-02-17 09:59:59 19
ANDES
 
Resource Report
Resource Website
10+ mentions
ANDES (RRID:SCR_002791) software application, data processing software, data analysis software, software resource, software toolkit Software library and a suite of applications, written in Perl and R, for deep sequencing statistical analyses. deep sequencing, biomarker detection, statistical analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:20633290 Free, Freely available, Available for download biotools:andes, OMICS_01119 https://bio.tools/andes SCR_002791 Statistical tools for the Analyses of Deep Sequencing (ANDES), Statistical tools for the Analyses of Deep Sequencing, Statistical tools for the ANalyses of Deep Sequencing 2026-02-17 10:00:03 25
NCBI database of Genotypes and Phenotypes (dbGap)
 
Resource Report
Resource Website
500+ mentions
NCBI database of Genotypes and Phenotypes (dbGap) (RRID:SCR_002709) dbGaP storage service resource, data or information resource, database, service resource, data repository Database developed to archive and distribute clinical data and results from studies that have investigated interaction of genotype and phenotype in humans. Database to archive and distribute results of studies including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits. clinical, trial, genotype, interaction, homology, cell, morphology, interaction, phenotype, molecular diagnosis, genetic recombination, gold standard, bio.tools is used by: International Genomics of Alzheimers Project
is used by: NIDDK Inflammatory Bowel Disease Genetics Consortium
is used by: NIH Heal Project
is used by: Genomic Data Commons Data Portal (GDC Data Portal)
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: NIDDK Central Repository
is related to: eMERGE Network: electronic Medical Records and Genomics
is related to: Framingham Heart Study
is related to: PhenoExplorer
is related to: Chronic Renal Insufficiency Cohort Study
is related to: DbGaP Cleaner
is related to: Psychiatric Genomics Consortium
is related to: ISCA Consortium
is related to: Allen Institute for Brain Science
has parent organization: NCBI
is parent organization of: Resource for Genetic Epidemiology Research on Adult Health and Aging
NLM PMID:24297256
PMID:17898773
Restricted nif-0000-23342, OMICS_00263, biotools:dbgap, r3d100010788 http://www.ncbi.nlm.nih.gov/sites/entrez?db=gap
https://bio.tools/dbgap
https://doi.org/10.17616/R3GS4K
SCR_002709 database of Genotypes and Phenotypes (dbGaP), dbGaP, NCBI, Database of Genotypes and Phenotypes 2026-02-17 10:00:01 683
discoSnp
 
Resource Report
Resource Website
1+ mentions
discoSnp (RRID:SCR_002612) software application, data processing software, data analysis software, software resource, sequence analysis software Software designed for discovering Single Nucleotide Polymorphism (SNP) from raw sets of reads obtained with Next Generation Sequencers (NGS). single nucleotide polymorphism, snp discovery, discover snp, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
SOFIPROTEOL under the FASO project PEAPOL ;
INRIA ANR-12-BS02-0008
PMID:25404127 Free, Freely available biotools:discosnp, OMICS_00267 https://bio.tools/discosnp
https://sources.debian.org/src/discosnp/
SCR_002612 DiscoSnp++, discovering Single Nucleotide Polymorphism, discovering Single Nucleotide Polymorphism (discoSNP) 2026-02-17 09:59:49 9
SuperPred: Drug classification and target prediction
 
Resource Report
Resource Website
SuperPred: Drug classification and target prediction (RRID:SCR_002691) SuperPred data access protocol, data or information resource, database, web service, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 24,2025. Publicly available web-server to predict medical indication areas based on properties and similarity of chemical compounds. The web-server translates a user-defined molecule into a structural fingerprint that is compared to about 6300 drugs, which are enriched by 7300 links to molecular targets of the drugs, derived through text mining followed by manual curation. Links to the affected pathways are provided. The similarity to the medical compounds is expressed by the Tanimoto coefficient that gives the structural similarity of two compounds. A similarity score higher than 0.85 results in correct ATC prediction for 81% of all cases. As the biological effect is well predictable, if the structural similarity is sufficient, the web-server allows prognoses about the medical indication area of novel compounds and to find new leads for known targets. The combination of physicochemical property and similarity searching provides the possibility to detect new biologically active compounds and novel targets for drug-like compounds. SuperPred can be applied for drug repositioning purposes, too. A further intention of SuperPred is to find side effects elicited by drugs caused through off-target hits. drug, drug class, drug target, addiction, anatomical therapeutic chemical, application area, biological activity, chemical, chemical classification, chemical property, classification, compound, molecular target, molecule, nervous system, pathway, pharmacological property, physicochemical property, prediction, activity spectra, substance, structural similarity, structure, tanimoto coefficient, tanimoto score, target prediction, target-prediction server, therapeutic approach, therapeutic property, drug classification, target prediction, similarity score, target, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Charite - Universitatsmedizin Berlin; Berlin; Germany
SFB 449 ;
IRTG Berlin-Boston-Kyoto and Deutsche Krebshilfe. ;
DFG
PMID:18499712
PMID:24878925
THIS RESOURCE IS NO LONGER IN SERVICE biotools:superpred, nif-0000-00415 https://bio.tools/superpred SCR_002691 2026-02-17 10:00:02 0
Rainbow
 
Resource Report
Resource Website
10+ mentions
Rainbow (RRID:SCR_002724) software application, data processing software, data analysis software, software resource, sequence analysis software Software developed to provide an ultra-fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. software, tool, clustering, assembling, short, read, restriction, site, DNA, sequence, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22942077
DOI:10.1093/bioinformatics/bts482
Free, Freely available, Available for download SCR_015992, OMICS_03722, biotools:rainbow https://bio.tools/rainbow
https://sources.debian.org/src/bio-rainbow/
SCR_002724 RAD-seq: Restriction-site Associated DNA sequencing, Bio-rainbow, RAD-seq 2026-02-17 10:00:02 41
Coding Potential Calculator
 
Resource Report
Resource Website
100+ mentions
Coding Potential Calculator (RRID:SCR_002764) CPC production service resource, analysis service resource, service resource, software resource, data analysis service A Support Vector Machine-based classifier to assesses the protein-coding potential of a transcript based on six biologically meaningful sequence features. CPC can discriminate coding from noncoding transcripts with high accuracy and speed. In addition to predicting the coding potential of the input transcripts, the CPC web server also graphically displays detailed sequence features and additional annotations of the transcript that may facilitate users' further investigation. The coding potential calculator tool reads FASTA data format as input. fasta, transcript, protein coding, coding potential, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Peking University; Beijing; China
PMID:17631615 Free, Freely available biotools:cpc, rid_000106 https://bio.tools/cpc SCR_002764 2026-02-17 09:59:58 198
Human Disease Ontology
 
Resource Report
Resource Website
1+ mentions
Human Disease Ontology (RRID:SCR_000476) DO data or information resource, ontology, database, controlled vocabulary Comprehensive hierarchical controlled vocabulary for human disease representation.Open source ontology for integration of biomedical data associated with human disease. Disease Ontology database represents comprehensive knowledge base of inherited, developmental and acquired human diseases. obo, pathological, organismal, cellular, disease, biomedical, health, neurologic disease, neurological disorder, phenotype, bio.tools, is used by: DOAF
is listed by: BioPortal
is listed by: OBO
is listed by: bio.tools
is listed by: Debian
is related to: PharmGKB Ontology
is related to: GWASdb
is related to: NUgene Project
is related to: FunDO
is related to: Neurocarta
has parent organization: University of Maryland School of Medicine; Maryland; USA
NHGRI U24 HG012557 PMID:22080554 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-35926, nlx_157432, SCR_003491, biotools:disease_ontology http://disease-ontology.org/
https://bio.tools/disease_ontology
http://purl.obolibrary.org/obo/doid.obo
http://do-wiki.nubic.northwestern.edu/index.php/Main_Page SCR_000476 Human Disease Ontology Knowledgebase, Disease Ontology 2026-02-17 09:59:27 5
AETIONOMY
 
Resource Report
Resource Website
1+ mentions
AETIONOMY (RRID:SCR_000232) AETIONOMY data or information resource, portal, organization portal, consortium Consortium founded to establish mechanism-based taxonomies for Alzheimer's and Parkinson's disease and other neurodegenerative disorders (NDD), with the goal of facilitating development of more effective and targeted treatments. To do this, the consortium collects and analyzes data to: * Create new ways to combine underutilized data currently available in the literature, public databases, and from private companies * Determine how to dynamically organize and structure different types of knowledge about NDD * Determine how to apply this knowledge to construct new patient group classification * Identify correlations between disease features at molecular, tissue or organ-specific, and clinical levels * Identify sub-groups of patients based on the molecular cause of their disease, as opposed to the nature and location of their symptoms * Deliver data, tools, and recommendations for the biomedical community in the treatment of NDD A mechanism-based taxonomy is hoped to advance the: # Description and organization of the indication-specific data # Linking of data to disease models, based on causal and correlative relationships The expected outcome of AETIONOMY is a new NDD taxonomy system that distinguishes mixed pathologies, allowing for new features or classes to be added into the taxonomy, all with the goal of aiding drug and biomarker discovery. drug development, drug, taxonomy, biomarker, etiology, epidemiology, neuroimaging, mechanism, clinical, clinical trial, database, classification, biological pathway, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Fraunhofer Institute for Algorithms and Scientific Computing SCAI; North Rhine-Westphalia; Germany
IMI ;
EFPIA
nlx_157972, biotools:AETIONOMY https://bio.tools/AETIONOMY SCR_000232 2026-02-17 09:59:25 3
RSEM
 
Resource Report
Resource Website
50+ mentions
RSEM (RRID:SCR_000262) data analysis software, software application, data processing software, software resource Software package for quantifying gene and isoform abundances from single end or paired end RNA Seq data. Accurate transcript quantification from RNA Seq data with or without reference genome. Used for accurate quantification of gene and isoform expression from RNA-Seq data. quantifying, gene, isoform, abundance, single, end, paired, RNA seq, data, transcript, reference, genome, bio.tools is listed by: OMICtools
is listed by: GitHub
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
PMID:21816040 Free, Available for download, Freely available OMICS_01966, OMICS_01287, biotools:rsem, SCR_013027 https://github.com/deweylab/RSEM
https://github.com/deweylab/RSEM/releases
https://bio.tools/rsem
https://sources.debian.org/src/rsem/
SCR_000262 RSEM, RNA-Seq by Expectation-Maximization, RSEM-v1.3.0 2026-02-17 09:59:25 94
DESeq
 
Resource Report
Resource Website
100+ mentions
DESeq (RRID:SCR_000154) DESeq data analysis software, software application, data processing software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression. gene expression, binomial, differential, negative binomial distribution, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is hosted by: Bioconductor
PMID:20979621
DOI:10.1186/s13059-014-0550-8
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01306, biotools:deseq https://bio.tools/deseq
https://sources.debian.org/src/r-bioc-deseq2/
SCR_000154 2026-02-17 09:59:24 473
POPBAM
 
Resource Report
Resource Website
POPBAM (RRID:SCR_000464) POPBAM data analysis software, software application, data processing software, software resource A tool to perform evolutionary or population-based analyses of next-generation sequencing data. POPBAM takes a BAM file as its input and can compute many widely used evolutionary genetics measures in sliding windows across a genome. next-generation sequencing, evolution, population, bam, genome, evolutionary genetics, c++, short read, sequence alignment, sliding window, command-line, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: University of Rochester; New York; USA
PMID:24027417 Free, Available for download, Freely available biotools:popbam, OMICS_01559 https://bio.tools/popbam http://popbam.sourceforge.net/ SCR_000464 2026-02-17 09:59:27 0
GASV
 
Resource Report
Resource Website
1+ mentions
GASV (RRID:SCR_000061) GASV data analysis software, software application, data processing software, software resource Software tool for identifying structural variants (SVs) from paired-end sequencing data.GASV distribution includes three components that are typically run in succession: the BAM file of unique paired-read mappings is processed; structural variants are identified by clustering discordant fragments; and a probabilistic algorithm improves the specificity of GASV predictions. paired-end sequencing data, structural variant, probabilistic algorithm, discordant fragment, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GASVPro
has parent organization: Brown University; Rhode Island; USA
Burroughs Wellcome Fund ;
Department of Defense Breast Cancer Research ;
ADVANCE Program at Brown University ;
NSF 0548311
PMID:19477992 Free, Available for download, Freely available biotools:gasv, OMICS_01352 http://compbio.cs.brown.edu/projects/gasv/
https://bio.tools/gasv
SCR_000061 Geometric Analysis of Structural Variants 2026-02-17 09:59:23 4
BAIT
 
Resource Report
Resource Website
1+ mentions
BAIT (RRID:SCR_000511) BAIT software application, data processing software, data analysis software, software resource, data visualization software Software to create strand inheritance plots in data derived from the Strand-Seq sequencing protocol. The software is designed to be flexible with a range of species, and basic template folders can called to read in species-specific data. create strand inheritance plots, strand-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24028793 Free, Available for download, Freely available biotools:bait, OMICS_01531 https://bio.tools/bait SCR_000511 BAIT - Software to help analyse Strand-Seq data 2026-02-17 09:59:28 1
MPscan
 
Resource Report
Resource Website
MPscan (RRID:SCR_000587) MPscan data access protocol, web service, software resource Web tool for index free mapping of multiple short reads on a genome. linux, macos, next-generation sequencing, genome, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: ATGC: Montpellier bioinformatics platform
Free, Available for download, Freely available biotools:mpscan, OMICS_00670 https://bio.tools/mpscan SCR_000587 MPscan: index free mapping of multiple short reads on a genome 2026-02-17 09:59:28 0
SplitSeek
 
Resource Report
Resource Website
1+ mentions
SplitSeek (RRID:SCR_001012) software application, data processing software, data analysis software, software resource, sequence analysis software THIS RESOURCE IS NO LONGER IN SERVICE, documented September 20, 2016. A program for de novo prediction of splice junctions in RNA-seq data. bioinformatics alignment, sequence analysis software, de novo, prediction, rna seq, rna, splice junction, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20236510 THIS RESOURCE IS NO LONGER IN SERVICE biotools:splitseek, OMICS_01253 https://bio.tools/splitseek http://www.uppmax.uu.se/software/splitseek SCR_001012 2026-02-17 09:59:33 1
Skylign
 
Resource Report
Resource Website
10+ mentions
Skylign (RRID:SCR_001176) Skylign production service resource, analysis service resource, service resource, software resource, data analysis service A tool for creating logos representing both sequence alignments and profile hidden Markov models. The interactive logos enable scrolling, zooming, and inspection of underlying values. Skylign can avoid sampling bias in sequence alignments by down-weighting redundant sequences and by combining observed counts with informed priors. It also simplifies the representation of gap parameters, and can optionally scale letter heights based on alternate calculations of the conservation of a position. sequence alignment, profile, logo, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Janelia Research
PMID:24410852 Creative Commons Attribution License, v3 Unported biotools:skylign, OMICS_02182 https://bio.tools/skylign SCR_001176 Skylign - Interactive logos for alignments and profile HMMs 2026-02-17 09:59:36 13
sim4cc
 
Resource Report
Resource Website
sim4cc (RRID:SCR_001204) software application, data processing software, software resource, image analysis software, alignment software Software tool as cross species spliced alignment program.Heuristic sequence alignment tool for comparing cDNA sequence with genomic sequence containing homolog of gene in another species. Cross species spliced alignment, unix, sequence alignment, cdna sequence, genomic sequence, homolog, gene, splice, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Johns Hopkins University; Maryland; USA
NSF CLS20163A;
Sloan Research Fellowship ;
NLM R01 LM006845
PMID:19429899 Free, Available for download, Freely available biotools:sim4cc, OMICS_02145 https://bio.tools/sim4cc SCR_001204 2026-02-17 09:59:35 0
bsseq
 
Resource Report
Resource Website
1+ mentions
bsseq (RRID:SCR_001072) software application, data processing software, data analysis software, software resource, sequence analysis software R package with tools for analyzing and visualizing bisulfite sequencing data. bisulfite sequencing, analyze, r, sequence analysis software, data analysis software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01847, biotools:bsseq https://bio.tools/bsseq SCR_001072 bsseq - Analyze manage and store bisulfite sequencing data 2026-02-17 09:59:34 8
AutoAssemblyD
 
Resource Report
Resource Website
AutoAssemblyD (RRID:SCR_001087) software application, data processing software, data analysis software, software resource, sequence analysis software Software which performs local and remote genome assembly by several assemblers based on an XML Template which can replace the large command lines required by most assemblers. genome, genome assembly, xml, sequence analysis software, local genome assembly, remote genome assembly, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24143057 Free, Available for download, Freely available biotools:autoassemblyd, OMICS_00874 https://bio.tools/autoassemblyd SCR_001087 2026-02-17 09:59:35 0

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