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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MACH
 
Resource Report
Resource Website
500+ mentions
MACH (RRID:SCR_009621) software application, data processing software, data analysis software, software resource QTL analysis based on imputed dosages/posterior_probabilities. genetic association, genomic analysis, imaging genomics, snp, gene, quantitative trait analysis, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
PMID:21058334
PMID:19715440
DOI:10.1002/gepi.20533
Free, Non-commercial, Acknowledgement requested nlx_155856, biotools:mach http://www.nitrc.org/projects/mach
https://bio.tools/mach
https://sources.debian.org/src/mach-haplotyper/ SCR_009621 mach2qtl, MaCH 2026-02-15 09:20:13 925
LIMMA
 
Resource Report
Resource Website
10000+ mentions
LIMMA (RRID:SCR_010943) LIMMA software application, data processing software, data analysis software, software resource Software package for the analysis of gene expression microarray data, especially the use of linear models for analyzing designed experiments and the assessment of differential expression. analysis, gene, expression, microarray, data, linear, model, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: GEO2R
is related to: Bioconductor
Free, Available for download, Freely available biotools:limma, OMICS_00769 https://omictools.com/limma-tool
https://bio.tools/limma
https://sources.debian.org/src/r-bioc-limma/
SCR_010943 Linear Models for Microarray Data 2026-02-15 09:20:21 24583
MutPred
 
Resource Report
Resource Website
100+ mentions
MutPred (RRID:SCR_010778) MutPred web application, software resource Web application tool developed to classify an amino acid substitution as disease-associated or neutral in human. bio.tools is used by: HmtVar
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Indiana University; Indiana; USA
biotools:mutpred, OMICS_00154 https://bio.tools/mutpred SCR_010778 2026-02-15 09:20:24 409
KisSplice
 
Resource Report
Resource Website
10+ mentions
KisSplice (RRID:SCR_011893) KisSplice software application, data processing software, data analysis software, software resource Software tool that enables analysis of RNA-seq data with or without reference genome. Local transcriptome assembler for SNPs, indels and AS events. RNA-seq data analysis, with reference genome, without reference genome, local transcriptome assembler, SNPs, indels, AS events., bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1186/1471-2105-13-S6-S5 Free, Available for download, Freely available biotools:KisSplice, OMICS_01321 https://bio.tools/KisSplice
https://sources.debian.org/src/kissplice/
SCR_011893 2026-02-15 09:20:07 20
CANGS
 
Resource Report
Resource Website
1+ mentions
CANGS (RRID:SCR_011837) CANGS software application, data processing software, data analysis software, software resource A user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies. windows, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
PMID:20180949 biotools:cangs, OMICS_01084 https://bio.tools/cangs SCR_011837 2026-02-15 09:20:27 1
sabre
 
Resource Report
Resource Website
100+ mentions
sabre (RRID:SCR_011843) sabre software application, data processing software, data analysis software, software resource Software tool to demultiplex barcoded reads into separate files. Works on both single-end and paired-end data in fastq format. Used in next generation sequencing to analyze a broad range of data. demultiplex, bardcode, separate, fastq, format, data, next, generation, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:sabre, OMICS_01090 https://bio.tools/sabre SCR_011843 Systems Approach to Biomarker Research 2026-02-15 09:20:24 199
NGSEP
 
Resource Report
Resource Website
50+ mentions
NGSEP (RRID:SCR_012827) NGSEP software application, data processing software, data analysis software, software resource Software whose main functionality is the variants detector, which allows to make simultaneous discovery of SNVs, small indels, and CNVs.Accurate variant calling across species and sequencing protocols.Used for analysis of DNA high throughput sequencing data. matlab, variants detector, SNVs discovery, CNVs discovery, variant calling, species, sequencing protocols, bio.tools is listed by: bio.tools PMID:31099384 Free, Available for download, Freely available OMICS_00067, biotools:NGSEP https://bio.tools/NGSEP SCR_012827 NGSEP3, Next Generation Sequencing Eclipse Plugin, Next Generation Sequencing Experience Platform 2026-02-15 09:20:39 69
affy
 
Resource Report
Resource Website
1000+ mentions
affy (RRID:SCR_012835) Affy software application, data processing software, data analysis software, software resource Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis. analysis, oligonucleotide, array, Affymetrix, process, probe, data, function, bio.tools is listed by: OMICtools
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: affydata
is related to: R Project for Statistical Computing
is related to: OMICtools
Danish Biotechnology Instrument Center PMID:14960456 Free, Available for download, Freely available BioTools:affy, OMICS_00740, biotools:affy https://bio.tools/affy
https://sources.debian.org/src/r-bioc-affy/
SCR_012835 Affymetrix, analysis of Affymetrix GeneChip data at the probe level, analysis of Affymetrix GeneChip data 2026-02-15 09:20:39 2996
edgeR
 
Resource Report
Resource Website
10000+ mentions
edgeR (RRID:SCR_012802) edgeR software application, data processing software, data analysis software, software resource Bioconductor software package for Empirical analysis of Digital Gene Expression data in R. Used for differential expression analysis of RNA-seq and digital gene expression data with biological replication. empirical, analysis, digital, gene, expression, data, R, RNA-seq data, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SARTools
is related to: Bioconductor
works with: tximport
NHMRC 406657;
Independent Research Institutes Infrastructure Support Scheme 361646;
Victorian State Government OIS grant ;
Melbourne International Research Scholarship ;
Harris and IBS Honours scholarships
PMID:19910308
DOI:10.1093/bioinformatics/btp616
Free, Available for download, Freely available OMICS_01308, biotools:edger https://bio.tools/edger
https://sources.debian.org/src/r-bioc-edger/
SCR_012802 edgeR, empirical analysis of digital gene expression data in R, Empirical analysis of Digital Gene Expression data in R 2026-02-15 09:20:39 21899
ENIGMA
 
Resource Report
Resource Website
100+ mentions
ENIGMA (RRID:SCR_013400) software application, data processing software, data analysis software, software resource A software tool to extract gene expression modules from perturbational microarray data, based on the use of combinatorial statistics and graph-based clustering. The modules are further characterized by incorporating other data types, e.g. GO annotation, protein interactions and transcription factor binding information, and by suggesting regulators that might have an effect on the expression of (some of) the genes in the module. Version : ENIGMA 1.1 used GO annotation version : Aug 29th 2007 genome, gene, genetic software, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
is parent organization of: ENIGMA-DTI Pipeline
PMID:18402676 biotools:enigma, nlx_144365 https://bio.tools/enigma SCR_013400 2026-02-15 09:20:27 130
CYANA
 
Resource Report
Resource Website
100+ mentions
CYANA (RRID:SCR_014229) software application, data processing software, data analysis software, software resource Software for automated structure calculation of biological macromolecules on basis of conformational constraints from nuclear magnetic resonance. Program for automated NMR protein structure calculation. CYANA requires a sufficient list of assigned chemical shifts and lists of cross-peak positions and columns from 2D, 3D, or4D NOESY spectra in order to calculate the assignment of the NOESY cross-peaks and the 3D structure of the protein in solution. protein structure, nmr, noesy, 3d structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Goethe University Frankfurt am Main; Hessen; Germany
has parent organization: RIKEN
PMID:15318003
PMID:25801209
Available to the academic community, Available to commercial user, Pay for license SCR_021949, biotools:cyana http://www.las.jp/english/products/cyana.html
https://bio.tools/cyana
https://dbpedia.org/page/CYANA_(software)
SCR_014229 2026-02-15 09:20:40 425
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) software application, data processing software, data analysis software, software resource Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-02-15 09:21:06 3702
fgsea
 
Resource Report
Resource Website
100+ mentions
fgsea (RRID:SCR_020938) software application, data processing software, data analysis software, software resource Software R package for fast preranked gene set enrichment analysis. Allows to make more permutations and get more fine grained p-values, which allows to use accurate stantard approaches to multiple hypothesis correction. Gene set enrichment analysis, preranked gene set, multiple hypothesis correction, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
DOI:10.1101/060012 Free, Available for download, Freely available biotools:fgsea https://github.com/ctlab/fgsea/
https://bio.tools/fgsea
SCR_020938 fast gene set enrichment analysis, Fast Gene Set Enrichment Analysis, FGSEA 2026-02-15 09:21:54 185
CRISPRcasIdentifier
 
Resource Report
Resource Website
1+ mentions
CRISPRcasIdentifier (RRID:SCR_018296) software application, data processing software, data analysis software, software resource Software tool providing machine learning approach for identification and classification of CRISPR-Cas systems. Combines regression and classification approaches for improving quality of input protein cassettes and predicting their subtypes. CRISPR-Cas, Machine Learning, Cas genes, Cas proteins, input protein cassette, predicting subtype, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/817619 Free, Available for download, Freely available biotools:crisprcasidentifier https://bio.tools/crisprcasidentifier SCR_018296 2026-02-15 09:22:13 4
SpoTyping
 
Resource Report
Resource Website
10+ mentions
SpoTyping (RRID:SCR_018466) software application, data processing software, data analysis software, software resource Software tool for fast and accurate in silico Mycobacterium spoligotyping from sequence reads. bio.tools is listed by: bio.tools
is listed by: Debian
National University of Singapore ;
Singapore ;
Singapore
DOI:10.1186/s13073-016-0270-7 Free, Available for download, Freely available biotools:spotyping https://bio.tools/spotyping SCR_018466 SpoTyping-v2.0, SpoTyping 2026-02-15 09:22:15 10
Graph2GO
 
Resource Report
Resource Website
1+ mentions
Graph2GO (RRID:SCR_018726) software application, data processing software, data analysis software, software resource Software tool as graph based representation learning method for protein function prediction. Multi modal graph based representation learning model that can integrate heterogeneous information including multiple types of interaction networks including sequence similarity network and protein-protein interaction network, and protein features including amino acid sequence, sub cellular location and protein domains, to predict protein functions on Gene Ontology. Protein function prediction, graph neural network, attributed network embedding, representation learning, multi-modal model, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ohio State University College of Medicine; Ohio; USA
Free, Available for download, Freely available SCR_018727, biotools:graph2go https://integrativeomics.shinyapps.io/graph2go/
https://bio.tools/graph2go
SCR_018726 2026-02-15 09:22:17 2
BioSimulations
 
Resource Report
Resource Website
BioSimulations (RRID:SCR_018733) web application, software resource Web tool for sharing and re-using biomodels, simulations, and visualizations of simulations results. Supports variety of modeling frameworks including kinetic, constraint based, and logical modeling, model formats including BNGL, CellML, SBML, and simulation tools including COPASI, libRoadRunner/tellurium, NFSim, VCell. Sharing, reusing, biomodel, simulation, visualization, simulation result, modeling framework support, simulation tool support, model format support, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
has parent organization: University of Connecticut; Connecticut; USA
NIBIB P41 EB023912;
NSF ;
NIGMS
Restricted biotools:biosimulations https://bio.tools/biosimulations SCR_018733 2026-02-15 09:22:23 0
BiG-SLiCE
 
Resource Report
Resource Website
1+ mentions
BiG-SLiCE (RRID:SCR_019130) software application, data processing software, data analysis software, software resource Software tool to perform large scale clustering analysis of Biosynthetic Gene Cluster data. Biosynthetic Gene, gene clusters, super linear clustering, clustering data analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Netherlands eScience Center Accelerating Scientific Discoveries Grant ;
Graduate School for Experimental Plant Sciences Netherlands
DOI:10.1101/2020.08.17.240838 Free, Available for download, Freely available biotools:big_slice https://bio.tools/big_slice SCR_019130 Biosynthetic Gene clusters - Super Linear Clustering Engine 2026-02-15 09:22:27 5
runBioSimulations
 
Resource Report
Resource Website
1+ mentions
runBioSimulations (RRID:SCR_019110) web application, software resource Web tool for executing broad range of modeling studies and visualizing their results. Provides web interface for reusing any model. Models, simulations, and visualizations are available under licenses specified for each resource. Executing modeling studies, visualization, model reusing, simulation, bio.tools uses: BioSimulators
is listed by: bio.tools
is listed by: Debian
Center for Reproducible Biomodeling Modeling ;
National Institute of Bioimaging and Bioengineering ;
National Institute of General Medical Sciences ;
NSF ;
NIH
Free, Freely available biotools:runbiosimulations https://bio.tools/runbiosimulations SCR_019110 2026-02-15 09:22:22 3
BioSimulators
 
Resource Report
Resource Website
1+ mentions
BioSimulators (RRID:SCR_019111) web application, software resource, software repository Web tool as collection of containerized biosimulation tools that provide consistent interfaces and guide to choosing simulator. Helps to find simulation tools that have capabilities, including supported modeling frameworks, simulation algorithms, and modeling formats, needed for specific modeling projects. Containerized biosimulation tools, consistent interfaces, choosing simulator guide, supported modeling frameworks, simulation algorithms, modeling formats, bio.tools is used by: runBioSimulations
is listed by: bio.tools
is listed by: Debian
Center for Reproducible Biomodeling Modeling ;
National Institute of Bioimaging and Bioengineering ;
National Institute of General Medical Sciences ;
National Institutes of Health ;
National Science Foundation
Free, Freely available biotools:biosimulators https://bio.tools/biosimulators SCR_019111 2026-02-15 09:21:48 5

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