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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
drFAST
 
Resource Report
Resource Website
1+ mentions
drFAST (RRID:SCR_000586) drFAST software resource A software which maps di-base reads (SOLiD color space reads) to reference genome assemblies in a fast and memory-efficient manner. di-base, solid color space, genome assemblies, memory-efficient, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: SourceForge
PMID:21586516 Free, Available for download, Freely available biotools:drfast, OMICS_00661 https://bio.tools/drfast SCR_000586 di-base read Fast Alignment Search Tool, drFAST: di-base read Fast Alignment Search Tool 2026-02-14 01:59:46 1
Genome BioInformatics Research Lab - gff2ps
 
Resource Report
Resource Website
1+ mentions
Genome BioInformatics Research Lab - gff2ps (RRID:SCR_000462) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software program for visualizing annotations of genomic sequences. The program has features such as the ability to create comprehensive plots, customizable parameters, and flexibility in file format. genome, sequence, visualization, parameters, bioinformatics, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:11099262
DOI:10.1093/bioinformatics/16.8.743
Free, Available for download, Freely available OMICS_17140, biotools:gff2ps, nif-0000-30611 https://bio.tools/gff2ps
https://sources.debian.org/src/gff2ps/
SCR_000462 gff2ps 2026-02-14 01:59:44 1
Rdisop
 
Resource Report
Resource Website
Rdisop (RRID:SCR_000453) software resource Software for identification of metabolites using high precision mass spectrometry. MS Peaks are used to derive a ranked list of sum formulae, alternatively for a given sum formula the theoretical isotope distribution can be calculated to search in MS peak lists. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02416, biotools:rdisop https://github.com/sneumann/Rdisop
https://bio.tools/rdisop
SCR_000453 Rdisop - Decomposition of Isotopic Patterns, Rdisop: Decomposition of Isotopic Patterns, Decomposition of Isotopic Patterns 2026-02-14 01:59:43 0
ContEst
 
Resource Report
Resource Website
1+ mentions
ContEst (RRID:SCR_000595) ContEst software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. A software tool (and method) for estimating the amount of cross-sample contamination in next generation sequencing data. java, contamination, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Broad Institute
PMID:21803805 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01038, biotools:contest https://bio.tools/contest SCR_000595 2026-02-14 01:59:49 6
FlipFlop
 
Resource Report
Resource Website
FlipFlop (RRID:SCR_000625) software resource Software that discovers which isoforms of a gene are expressed in a given sample together with their abundances, based on RNA-Seq read data. standalone software, unix/linux, mac os x, windows, r, rna-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24813214 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04028, biotools:flipflop https://bio.tools/flipflop SCR_000625 flipflop - Fast lasso-based isoform prediction as a flow problem 2026-02-14 01:59:50 0
BLASR
 
Resource Report
Resource Website
10+ mentions
Discontinued
BLASR (RRID:SCR_000764) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. C++ long-read aligner for PacBio reads., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Proovread
PMID:22988817
DOI:10.1186/1471-2105-13-23
THIS RESOURCE IS NO LONGER IN SERVICE biotools:blasr, OMICS_05134 https://bio.tools/blasr
https://sources.debian.org/src/blasr/
SCR_000764 Basic Local Alignment with Successive Refinement, BLASR: The PacBio long read aligner 2026-02-14 01:59:49 15
GMcloser
 
Resource Report
Resource Website
1+ mentions
GMcloser (RRID:SCR_000646) GMcloser software resource Software that fills and closes the gaps present in scaffold assemblies, especially those generated by the de novo assembly of whole genomes with next-generation sequencing (NGS) reads. Unlike other gap-closing tools that use only NGS reads, GMcloser uses preassembled contig sets or long read sets as the sequences to close gaps and uses paired-end (PE) reads and a likelihood-based algorithm to improve the accuracy and efficiency of gap closure. The efficiency of gap closure can be increased by successive treatments with different contig sets. scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:26261222 Free, Available for download, Freely available biotools:gmcloser, OMICS_00042 https://bio.tools/gmcloser SCR_000646 Gmcloser - Closing the gaps in scaffolds with preassembled contigs 2026-02-14 01:59:50 3
clipcrop
 
Resource Report
Resource Website
clipcrop (RRID:SCR_000678) software resource Software tool for detecting structural variations with single-base resolution using soft-clipping information from SAM files. structural variation, detecting structural variations, soft-clipping information, SAM files, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22373054 Free, Available for download, Freely available biotools:clipcrop, OMICS_00310 https://bio.tools/clipcrop SCR_000678 ClipCrop 2026-02-14 01:59:48 0
TriageTools
 
Resource Report
Resource Website
TriageTools (RRID:SCR_000675) TriageTools software resource A collection of tools for partitioning raw data (fastq reads) from high-throughput sequencing projects. The tools are designed for basic data management as well for prioritizing analysis of certain subsets. matlab, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23408855 Free, Available for download, Freely available biotools:triagetools, nlx_156740 https://bio.tools/triagetools SCR_000675 2026-02-14 01:59:48 0
PerM
 
Resource Report
Resource Website
50+ mentions
PerM (RRID:SCR_004223) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package to perform highly efficient genome scale alignments for hundreds of millions of short reads produced by the ABI SOLiD and Illumina sequencing platforms. It capable of providing full sensitivity for alignments within 4 mismatches for 50bp SOLID reads and 9 mismatches for 100bp Illumina reads.Efficient mapping of short sequencing reads with periodic full sensitive spaced seeds. Short sequencing mapping, short sequencing read, next-generation sequencing, genome, alignment, short read, abi, solid, illumina, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Clippers
has parent organization: Google Code
has parent organization: University of Southern California; Los Angeles; USA
PMID:19675096
DOI:10.1093/bioinformatics/btp486
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00675, biotools:perm https://bio.tools/perm
https://sources.debian.org/src/perm/
SCR_004223 PERiodic seed Mapping, Periodic seed Mapping 2026-02-14 02:00:38 60
BioPig
 
Resource Report
Resource Website
1+ mentions
BioPig (RRID:SCR_004636) BioPig software resource Software providing a framework for genomic data analysis using Apache Pig and Hadoop. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
PMID:24021384 biotools:biopig, OMICS_01225 https://bio.tools/biopig SCR_004636 2026-02-14 02:00:58 2
SLIQ
 
Resource Report
Resource Website
1+ mentions
SLIQ (RRID:SCR_005003) SLIQ software resource Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph. python, scaffolding, contig position, contig orientation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:23057825 biotools:sliq, OMICS_00048 https://bio.tools/sliq SCR_005003 Simple linear inequalities, SLiQ: Simple linear inequalities based Mate-Pair reads filtering and scaffolding 2026-02-14 02:01:03 3
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2026-02-14 02:00:48 20
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace
https://sources.debian.org/src/sspace/
SCR_005056 2026-02-14 02:01:02 426
hot scan
 
Resource Report
Resource Website
1+ mentions
hot scan (RRID:SCR_002840) software resource A free software to detect genomic regions unusually rich in translocation breakpoints. More generally, it may be used to detect a region that is unusually rich in a given character of a binary sequence. software package, perl, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24860160 Free, Freely available, Available for download biotools:hot_scan, OMICS_05200 https://bio.tools/hot_scan SCR_002840 hot_scan 2026-02-14 02:00:33 6
SMRT-Analysis
 
Resource Report
Resource Website
100+ mentions
SMRT-Analysis (RRID:SCR_002942) software resource Open-source bioinformatics software suite for analyzing single molecule, real-time DNA sequencing data. Users can choose from a variety of analysis protocols that utilize PacBio and third-party tools. Analysis protocols include de novo genome assembly, cDNA mapping, DNA base-modification detection, and long-amplicon analysis to determine phased consensus sequences. software suite is listed by: OMICtools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_05142 http://www.pacb.com/devnet/
https://sources.debian.org/src/smrtanalysis/
SCR_002942 SMRT Analysis 2026-02-14 02:00:20 134
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-02-14 02:00:29 4
BRAIN
 
Resource Report
Resource Website
10+ mentions
BRAIN (RRID:SCR_003018) software resource Software package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23350948 GNU General Public License, v2 biotools:brain, OMICS_02410 https://bio.tools/brain SCR_003018 Baffling Recursive Algorithm for Isotopic distributioN calculations, Baffling Recursive Algorithm for Isotope distributioN 2026-02-14 02:00:21 44
SALT
 
Resource Report
Resource Website
1000+ mentions
SALT (RRID:SCR_003187) SALT software resource Software that can accurately and sensitivity classify short reads of next-generation sequencing (NGS) into protein domain families. It is based on profile HMM and a supervised graph contribution algorithm. Compared to existing tools, it has high sensitivity and specificity in classifying short reads into their native domain families. next-generation sequencing, protein, protein domain, short read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23782615 Free, Available for download, Freely available OMICS_01565, biotools:salt https://bio.tools/salt SCR_003187 SALT - Protein domain classifier 2026-02-14 02:00:30 1294
NovelSeq
 
Resource Report
Resource Website
NovelSeq (RRID:SCR_003136) NovelSeq software resource Software pipeline to detect novel sequence insertions using high throughput paired-end whole genome sequencing data. sequence, insertion, genome sequencing, genome, next-generation sequencing, illumina, unix, linux, c, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:20385726 Free, Available for download, Freely available biotools:novelseq, nlx_156791, OMICS_02164 https://mybiosoftware.com/novelseq-1-0-2-sequence-insertions-detection.html#google_vignette SCR_003136 NovelSeq: Novel Sequence Insertion Detection 2026-02-14 02:00:30 0

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