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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Mammalian Protein Complex Data Base
 
Resource Report
Resource Website
Mammalian Protein Complex Data Base (RRID:SCR_008209) data or information resource, database A database of manually annotated mammalian protein complexes. To obtain a high-quality dataset, information was extracted from individual experiments described in the scientific literature. Data from high-throughput experiments was not included. gene, genome, mammalian, protein, proteomics, structure The Munich Information Center for Protein Sequences ;
MPCDB
nif-0000-21273 SCR_008209 2026-02-14 02:06:34 0
FEED
 
Resource Report
Resource Website
FEED (RRID:SCR_000637) FEED data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Database of physiologic data and associated metadata related to feeding behavior for a number of mammalian species, including human. The data contain information on muscle activity, bone and muscle strain, jaw and oropharyngeal apparatus motion, and intra-oral pressure and were generated using several techniques (e.g., electromyography, cineradiography, sonomicrometry). The data are searchable and can be downloaded into csv format. appetitive activity, comparative anatomy, feeding behavior, muscle, pharynx, teeth, ontology, evolution, functional morphology, physiology, development, head, behavior, mouth, oral has parent organization: NESCent - National Evolutionary Synthesis Center NESCent - National Evolutionary Synthesis Center PMID:21700574 THIS RESOURCE IS NO LONGER IN SERVICE nlx_151995 https://github.com/NESCent/feedingdb/ SCR_000637 FEED: Feeding Experiments End-User Database, Feeding Experiments End-User Database 2026-02-14 02:06:58 0
Vector Database
 
Resource Report
Resource Website
1+ mentions
Vector Database (RRID:SCR_005907) Vector Database biomaterial supply resource, material resource Vector database is a digital collection of vector backbones assembled from publications and commercially available sources. This is a free resource for the scientific community that is compiled by Addgene. Only the plasmids deposited at Addgene are available for purchase through this website. vector, vector backbone, plasmid, mammalian expression, bacterial expression, retroviral, lentiviral, worm expression, insect expression, yeast expression, rnai, luciferase, mouse targeting, mammalian, bacterial, yeast, worm, insect, mouse, adenoviral, rnai, cre/lox, marker, neomycin, puromycin, hygromycin, zeocin, blasticidin, gentamicin, bacterial resistance, ampicillin, kanamycin, chloramphenicol, hygromycin, bleocin, zeocin is listed by: One Mind Biospecimen Bank Listing
is related to: ATCC
has parent organization: Addgene
Free nlx_149479 SCR_005907 Addgene Vector Database 2026-02-14 02:07:07 6
SpliceDB
 
Resource Report
Resource Website
1+ mentions
SpliceDB (RRID:SCR_006262) SpliceDB data or information resource, data set Database of canonical and non-canonical mammalian splice sites. The information about verified splice site sequences for canonical and non-canonical sites is presented with the supporting evidence. Weight matrices were built for the major splice groups, which can be incorporated into gene prediction programs. gene, expressed sequence tag, splice, canonical, non-canonical, splice site, sequence, data set, splice site sequence is listed by: OMICtools
is listed by: 3DVC
is related to: GenBank
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:11125105
PMID:11058137
nlx_151853, OMICS_01892 http://linux1.softberry.com/berry.phtml?topic=splicedb http://genomic.sanger.ac.uk/spldb/SpliceDB.htm SCR_006262 SpliceDB: canonical and non-canonical splice site sequences in mammalian genes 2026-02-14 02:07:52 2
Blue Brain Project
 
Resource Report
Resource Website
10+ mentions
Blue Brain Project (RRID:SCR_002994) Blue Brain data or information resource, portal, topical portal A Swiss-led project with the aim of reverse engineering the mammalian brain and achieving a complete virtual human brain. The researchers have demonstrated the validity of their method by developing a realistic model of a rat cortical column, consisting of about 10,000 neurons. The eventual goal is to simulate systems of millions and hundreds of millions of neurons. The virtual brain will be an exceptional tool giving neuroscientists a new understanding of the brain and a better understanding of neurological diseases. In five years of work, Henry Markram's team has perfected a facility that can create realistic models of one of the brain's essential building blocks. This process is entirely data driven and essentially automatically executed on the supercomputer. Meanwhile the generated models show a behavior already observed in years of neuroscientific experiments. These models will be basic building blocks for larger scale models leading towards a complete virtual brain. brain, neuron, microcircuit, simulation, cortex, cortical column, model is related to: NeuroCurator
has parent organization: Ecole Polytechnique Federale de Lausanne; Lausanne; Switzerland
is parent organization of: ChannelPedia
provides: Blue Brain Cell Atlas
Neurological disease nif-0000-30208 SCR_002994 Bluebrain 2026-02-14 02:00:36 16
Program on Ontologies of Neural Structures
 
Resource Report
Resource Website
Program on Ontologies of Neural Structures (RRID:SCR_003549) PONS portal, data or information resource, narrative resource, topical portal, standard specification Program consisting of three Task Forces and one Working Group to promote data exchange and integration in the neurosciences by developing terminology standards and formal ontologies for neural structures. Closely linked to the Program on Digital Brain Atlasing, the Program aims to establish a structured lexicon for the translation and definition of terms describing neural structures at multiple levels of granularity. The three Task Forces and one Working Group involved in the PONS effort: * Structural lexicon * Neuron registry * Representation and deployment * KnowledgeSpace Working Group Structural lexicon, Neuron registry, Representation and deployment, and KnowledgeSpace Working Group. neural structure, lexicon, neuroanatomy, brain, metadata, brain region, data sharing, neuron, interoperability is related to: NeuroLex
is related to: Neuron Registry Curator Interface
has parent organization: International Neuroinformatics Coordinating Facility
nlx_157669 SCR_003549 INCF Program on Ontologies of Neural Structures 2026-02-14 02:00:50 0
BioCyc
 
Resource Report
Resource Website
500+ mentions
BioCyc (RRID:SCR_002298) data or information resource, database A collection of Pathway/Genome Databases which describes the genome and metabolic pathways of a single organism. The BioCyc collection of Pathway/Genome Databases (PGDBs) provides an electronic reference source on the genomes and metabolic pathways of sequenced organisms. BioCyc PGDBs are generated by software that predicts the metabolic pathway complements of completely sequenced organisms from their genome sequences. They also include the results of a number of other computational inference procedures applied to these genomes, including predictions of which genes code for missing enzymes in metabolic pathways, and predicted operons. The BioCyc Web site provides a suite of software tools for database searching and visualization, for omics data analysis, and for comparative genomics and comparative pathway questions. The databases within the BioCyc collection are organized into tiers according to the amount of manual review and updating they have received. Tier 1 PGDBs have been created through intensive manual efforts, and receive continuous updating. Tier 2 PGDBs were computationally generated by the PathoLogic program, and have undergone moderate amounts of review and updating. Tier 3 PGDBs were computationally generated by the PathoLogic program, and have undergone no review and updating. There are 967 DBs in Tier 3. The downloadable version of BioCyc that includes the Pathway Tools software provides more speed and power than the BioCyc Web site. database, pathway/genome databases, PGDB, genome, metabolic pathway, microbiome, FASEB list uses: Pathway Tools
is used by: PathCase Pathways Database System
lists: Pathway Tools
lists: EcoCyc
lists: MetaCyc
lists: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is listed by: LabWorm
is listed by: Human Microbiome Project
is related to: Pathway Tools
is related to: PathCase Pathways Database System
is related to: EcoCyc
is related to: MetaCyc
is related to: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is related to: EcoCyc
is related to: Gramene
is related to: NCBI BioSystems Database
is related to: KOBAS
is related to: Tuberculosis Database
is related to: Pathway Tools
has parent organization: Stanford Research Institute International
NIGMS GM080746 PMID:16246909 Restricted nif-0000-00369, r3d100011259 https://doi.org/10.17616/R36G8H SCR_002298 BioCyc Database Collection 2026-02-14 02:00:23 970
MPO
 
Resource Report
Resource Website
10+ mentions
MPO (RRID:SCR_004855) MPO, MP data or information resource, ontology, controlled vocabulary Community ontology to provide standard terms for annotating mammalian phenotypic data. It has a hierarchical structure that permits a range of detail from high-level, broadly descriptive terms to very low-level, highly specific terms. This range is useful for annotating phenotypic data to the level of detail known and for searching for this information using either broad or specific terms as search criteria. Your input is welcome. mus, phenotype, obo is used by: NIF Data Federation
is listed by: BioPortal
is related to: Rat Genome Database (RGD)
is related to: MouseBook
is related to: Neurocarta
is related to: phenomeNET
has parent organization: OBO
has parent organization: Mouse Genome Informatics (MGI)
PMID:17989687 The community can contribute to this resource nlx_83784 http://obofoundry.org/cgi-bin/detail.cgi?id=mammalian_phenotype
http://purl.bioontology.org/ontology/MP
SCR_004855 Mammalian Phenotype Ontology 2026-02-14 02:00:48 19
CSHL - Hannon Lab
 
Resource Report
Resource Website
50+ mentions
CSHL - Hannon Lab (RRID:SCR_005982) Hannon Lab laboratory portal, data or information resource, organization portal, portal The Hannon laboratory comprises a broad spectrum of programs in small RNA biology, mammalian genetics and genomics. We study RNAi and related pathways in a wide variety of organisms to extract common themes that define both the mechanisms by which small RNAs act and the biological processes which they impact. Currently, we focus on microRNAs, endogenous siRNAs and piRNAs and their roles in gene regulation, cancer biology, stem cell biology and in defense of the genome against transposons. In collaboration with Steve Elledge (Harvard) and Scott Lowe (CSHL), we develop genome-wide shRNA tools for RNAi-based genetics in mammalian cells, and we are now producing similar collections of artificial microRNAs for Arabidopsis with Detlef Weigel (MPI), Dick McCombie (CSHL) and Rob Martienssen (CSHL) as part of the 2010 project (see 2010.cshl.edu). Our genomic efforts include the application of RNAi-based genetic screens to cancer biology and stem cells. We also make heavy use of next generation sequencing methodologies for probing small RNA populations, in part as a member of the ENCODE consortium (with Tom Gingeras, CSHL). Finally, we develop (with Dick McCombie) and apply focal re-sequencing methods for identifying disease relevant mutations, for probing the epigenetic landscape and for the study of human evolution. rnai, rna, mammal, genetics, genomics, microrna, sirna, pirna, gene regulation, cancer biology, stem cell biology, defense, genome, transposon, cancer, stem cell has parent organization: Cold Spring Harbor Laboratory nlx_151354 SCR_005982 Cold Spring Harbor Laboratory - Hannon Lab 2026-02-14 02:01:12 66
Brad Smith Magnetic Resonance Imaging of Embryos
 
Resource Report
Resource Website
Brad Smith Magnetic Resonance Imaging of Embryos (RRID:SCR_006300) Brad Smith MRI of Embryos data or information resource, image collection, data set, video resource Data set of image collections and movies including Magnetic Resonance Imaging of Embryos, Human Embryo Imaging, MRI of Cardiovascular Development, and Live Embryo Imaging. Individual MRI slice images, three-dimensional images, animations, stereo-pair animations, animations of organ systems, and photo-micrographs are included. embryo, magnetic resonance imaging, embryonic development, magnetic resonance microscopy, cardiovascular development, cardiovascular, development, heart, blood vessel, in-utero, in-vitro, embryonic mouse, newborn mouse, embryonic human is related to: Magnetic Resonance Microscopy of Mouse Embryo Specimens
is related to: Multi-Dimensional Human Embryo
has parent organization: University of Michigan; Ann Arbor; USA
Normal, Mutant, Gentically-manipulated nlx_151971 SCR_006300 Brad Smith Research MRI of Embryos, Brad Smith Research 2026-02-14 02:01:16 0
Common Upper Mammalian Brain Ontology
 
Resource Report
Resource Website
Common Upper Mammalian Brain Ontology (RRID:SCR_003629) CUMBO data or information resource, ontology, controlled vocabulary Ontology of formal definitions (i.e., machine processable) for the types of structures commonly described in neuroanatomy. neuroanatomy, brain is related to: Linked Neuron Data
has parent organization: International Neuroinformatics Coordinating Facility
has parent organization: NeuroLex
nlx_157809 http://neurolex.org/wiki/Cumbo_terms SCR_003629 INCF-CUMBO, Common Upper Mammalian Brain Ontology (CUMBO) 2026-02-14 02:00:52 0
MatrixDB
 
Resource Report
Resource Website
50+ mentions
MatrixDB (RRID:SCR_001727) MatrixDB data or information resource, production service resource, service resource, database Freely available database focused on interactions established by extracellular proteins and polysaccharides, taking into account the multimeric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB is an active member of the International Molecular Exchange (IMEx) consortium and has adopted the PSI-MI standards for annotating and exchanging interaction data. It includes interaction data extracted from the literature by manual curation, and offers access to relevant data involving extracellular proteins provided by the IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. The database reports mammalian protein-protein and protein-carbohydrate interactions involving extracellular molecules. Interactions with lipids and cations are also reported. MatrixDB is focused on mammalian interactions, but aims to integrate interaction datasets of model organisms when available. MatrixDB provides direct links to databases recapitulating mutations in genes encoding extracellular proteins, to UniGene and to the Human Protein Atlas that shows expression and localization of proteins in a large variety of normal human tissues and cells. MatrixDB allows researchers to perform customized queries and to build tissue- and disease-specific interaction networks that can be visualized and analyzed with Cytoscape or Medusa. Statistics (2013): 2283 extracellular matrix interactions including 2095 protein-protein and 169 protein-glycosaminoglycan interactions. extracellular, protein fragment, biomolecule, cation, cleavage, collagen, glycosaminoglycan, human, interaction, laminin, lipid, mammalian, matricryptin, matrikin, matrix, molecule, monomer, mulimerization, multimer, polysaccharide, protein, protein-carbohydrate interaction, protein-protein interaction, recognition, thrombospondin, interactome, extracellular protein, protein-polysaccharide interaction, extracellular interaction, molecular interaction, model organism, inorganic, small molecule-protein, small molecule, extracellular matrix protein, protein-glycosaminoglycan interaction, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Gene Ontology
is related to: PSI-MI
is related to: HPRD - Human Protein Reference Database
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: IntAct
has parent organization: Claude Bernard University Lyon 1; Lyon; France
European Union contract FP7-HEALTH-2007-223411 PMID:20852260
PMID:19147664
THIS RESOURCE IS NO LONGER IN SERVICE biotools:matrixdb, r3d100010672, nif-0000-10226 https://bio.tools/matrixdb
https://doi.org/10.17616/R3M03H
http://matrixdb.ibcp.fr/ SCR_001727 MatrixDB: Extracellular Matrix Interactions Database, Extracellular Matrix Interactions Database 2026-02-14 02:00:16 86
MouseCyc
 
Resource Report
Resource Website
1+ mentions
MouseCyc (RRID:SCR_001791) MouseCyc data analysis service, analysis service resource, data or information resource, production service resource, service resource, database A manually curated database of both known and predicted metabolic pathways for the laboratory mouse. It has been integrated with genetic and genomic data for the laboratory mouse available from the Mouse Genome Informatics database and with pathway data from other organisms, including human. The database records for 1,060 genes in Mouse Genome Informatics (MGI) are linked directly to 294 pathways with 1,790 compounds and 1,122 enzymatic reactions in MouseCyc. (Aug. 2013) BLAST and other tools are available. The initial focus for the development of MouseCyc is on metabolism and includes such cell level processes as biosynthesis, degradation, energy production, and detoxification. MouseCyc differs from existing pathway databases and software tools because of the extent to which the pathway information in MouseCyc is integrated with the wealth of biological knowledge for the laboratory mouse that is available from the Mouse Genome Informatics (MGI) database. energy production, biosynthesis, cell, cellular, degradation, detoxification, metabolism, mouse, physiological, enzymatic reaction, gene, disease, genome, metabolic pathway, pathway, compound, enzymatic reaction, protein, rna, reaction, blast, human, mammal, genetic, genomic is related to: Mouse Genome Informatics (MGI)
is related to: Gene Ontology
has parent organization: Jackson Laboratory
NHGRI HG003622 PMID:19682380 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10303 SCR_001791 MouseCyc database, Mouse Genome Informatics: MouseCyc database 2026-02-14 02:00:11 9
ERANGE
 
Resource Report
Resource Website
10+ mentions
ERANGE (RRID:SCR_005240) ERANGE software resource Software for Mapping and Quantifying Mammalian Transcriptomes by RNA-Seq. Its functions are to (i) assign reads that map uniquely in the genome to their site of origin and, for reads that match equally well to several sites (''multireads''), assign them to their most likely site(s) of origin; (ii) detect splice-crossing reads and assign them to their gene of origin; (iii) organize reads that cluster together, but do not map to an already known exon, into candidate exons or parts of exons; and (iv) calculate the prevalence of transcripts from each known or newly proposed RNA, based on normalized counts of unique reads, spliced reads and multireads. The new candidate RNA regions produced can be thought of as ESTs, and, like ESTs, some are provisionally appended to existing gene models if they meet several additional criteria. Remaining unassigned candidate transcribed regions (labeled RNAFAR features) can then be used in conjunction with other confirming data to develop new or revised gene models. transcriptome, rna-seq, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:18516045 OMICS_01274, biotools:erange https://bio.tools/erange SCR_005240 Enhanced Read Analysis of Gene Expression 2026-02-14 02:01:04 30
GOblet
 
Resource Report
Resource Website
1+ mentions
GOblet (RRID:SCR_006998) GOblet data analysis service, analysis service resource, production service resource, service resource, software application, software resource Tool that performs annotation based on GO and pathway terms for anonymous cDNA or protein sequences. It uses the species independent GO structure and vocabulary together with a series of protein databases collected from various sites, to perform a detailed GO annotation by sequence similarity searches. The sensitivity and the reference protein sets can be selected by the user. GOblet runs automatically and is available as a public service on our web server. GOblet expects query sequences to be in FASTA-Format (with header-lines). Protein and nucleotide sequences are accepted. Total size of all sequences submitted per request should not be larger than 50kb currently. For security reasons: Larger post's will be rejected. Due to limited capacities the queries may be processed in batches depending on the server load. The output of the BLAST job is filtered automatically and the relevant hits are displayed. In addition, the respective GO-terms are shown together with the complete GO-hierarchy of parent terms., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, sequence, cdna, ontology or annotation browser, pathway, term enrichment, clustering, virus, genomic, protein, nucleotide is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany
BMBF PMID:20134064
PMID:15215401
PMID:12824400
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30624, OMICS_02271 http://goblet.molgen.mpg.de SCR_006998 2026-02-14 02:01:19 6
ProtChemSI
 
Resource Report
Resource Website
1+ mentions
ProtChemSI (RRID:SCR_006115) ProtChemSI data or information resource, database The database of protein-chemical structural interactions includes all existing 3D structures of complexes of proteins with low molecular weight ligands. When one considers the proteins and chemical vertices of a graph, all these interactions form a network. Biological networks are powerful tools for predicting undocumented relationships between molecules. The underlying principle is that existing interactions between molecules can be used to predict new interactions. For pairs of proteins sharing a common ligand, we use protein and chemical superimpositions combined with fast structural compatibility screens to predict whether additional compounds bound by one protein would bind the other. The current version includes data from the Protein Data Bank as of August 2011. The database is updated monthly. protein, chemical, 3d structure, biological network, interaction, ligand, prediction, fasta, fasta sequence, smiles string, complex, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Heidelberg University; Baden-Wurttemberg; Germany
PMID:21573205 Acknowledgement requested nlx_151590, biotools:protchemsi https://bio.tools/protchemsi SCR_006115 Protein-Chemical Structural Interactions, ProtChemSI: protein-chemical interaction database, ProtChemSI - the database of protein-chemical structural interactions 2026-02-14 02:06:33 3
HaploReg
 
Resource Report
Resource Website
1000+ mentions
HaploReg (RRID:SCR_006796) HaploReg data or information resource, database HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-associated loci. Using linkage disequilibrium (LD) information from the 1000 Genomes Project, linked SNPs and small indels can be visualized along with their predicted chromatin state in nine cell types, conservation across mammals, and their effect on regulatory motifs. HaploReg is designed for researchers developing mechanistic hypotheses of the impact of non-coding variants on clinical phenotypes and normal variation. chromatin state, conservation, regulatory motif, alteration, variant, chromatin, motif, annotation, genome, variation, genome-wide association study, refsnp, refseq gene, snp, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Broad Institute
NHGRI R01-HG004037;
NHGRI RC1-HG005334;
NSF 0644282
PMID:22064851 biotools:HaploReg, nlx_151407 http://compbio.mit.edu/HaploReg
https://bio.tools/HaploReg
SCR_006796 2026-02-14 02:06:27 1004
MamPolMammalia Polymorphism Database
 
Resource Report
Resource Website
MamPolMammalia Polymorphism Database (RRID:SCR_007769) MamPol data or information resource, database Database providing a collection of all the existing polymorphic sequences in the Mammalia group. It allows the search for any polymorphic set according to different parameter values of nucleotide diversity. For data collection, diversity measures and updating they use PDA, a pipeline made of a set of Perl modules that automates the process of sequence retrieving, grouping, aligning and estimating diversity parameters from GenBank sequences. Diversity measures, including polymorphism estimates in synonymous and non-synonymous sites, linkage disequilibrium and codon bias, are calculated for each polymorphic set in different functional regions. The database also includes the primary information retrieved from different external sources: the mammalian publicly available nucleotide sequences (excluding ESTs, STSs, GSSs, working draft and patents) with their annotations and references from GenBank, and the cross-references to the PopSet database. The database content is daily updated, and records are assigned unique and permanent MamPol identification numbers to facilitate cross-database referencing. polymorphism has parent organization: Autonomous University of Barcelona; Barcelona; Spain nif-0000-03100 SCR_007769 2026-02-14 02:06:02 0
Cell Type Ontology
 
Resource Report
Resource Website
1+ mentions
Cell Type Ontology (RRID:SCR_004251) CL data or information resource, ontology, controlled vocabulary Ontology designed as a structured controlled vocabulary for cell types. It was constructed for use by the model organism and other bioinformatics databases. It includes cell types from prokaryotes, mammals, and fungi. The ontology is available in the formats adopted by the Open Biological Ontologies umbrella and is designed to be used in the context of model organism genome and other biological databases. cell ontology, ontology repository is listed by: BioPortal
is listed by: Ontology Lookup Service
is related to: CELDA Ontology
is related to: OBO
is related to: Cell Line Knowledge Base
BBSRC ;
MRC ;
NIH ;
NSF DBI-9978564;
NSF PGRP-0321666
PMID:15693950 Free, Freely available nlx_26501 http://purl.bioontology.org/ontology/CL http://cellontology.org, http://www.obofoundry.org/cgi-bin/detail.cgi?id=cell, SCR_004251 cellontology.org, Obo-cell-type, Cell Ontology 2026-02-14 02:04:28 6
UD Chick EST Project
 
Resource Report
Resource Website
10+ mentions
UD Chick EST Project (RRID:SCR_002236) biomaterial supply resource, cell repository, material resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 28,2025. A chicken EST Web site has been created to provide access to the data, and a set of unique sequences has been deposited with GenBank. This site contains over 40,000 EST sequences from the chicken cDNA libraries in the University of Delaware collection. Users can perform keyword searches, BLAST nucleotide sequences against our database, view clusters of similar or overlapping clones, and order clones. The cDNA and gene sequences of many mammalian cytokines and their receptors are known. However, corresponding information on avian cytokines is limited due to the lack of cross-species activity at the functional level or strong homology at the molecular level. To improve the efficiency of identifying cytokines and novel chicken genes, a directionally cloned cDNA library from T-cell-enriched activated chicken splenocytes was constructed, and the partial sequence of 5251 clones was obtained. Sequence clustering indicates that 2357 (42%) of the clones are present as a single copy, and 2961 are distinct clones, demonstrating the high level of complexity of this library. Comparisons of the sequence data with known DNA sequences in GenBank indicate that approximately 25% of the clones match known chicken genes, 39% have similarity to known genes in other species, and 11% had no match to any sequence in the database. Several previously uncharacterized chicken cytokines and their receptors were present in our library. This collection provides a useful database for cataloging genes expressed in T cells and a valuable resource for future investigations of gene expression in avian immunology. Therefore, the Chick EST database was created. gene, avian, cdna, chicken, clone, cytokine, dna, homology, immunology, mammalian, molecular, nucleotide, poultry, receptor, sequence, splenocyte, t cell is listed by: One Mind Biospecimen Bank Listing
has parent organization: University of Delaware; Delaware; USA
PMID:16554550 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-20971 SCR_002236 U.D. Chick EST Database, University of Delaware Chick EST Project, University of Delaware Chick EST Database 2026-02-14 02:05:02 18

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