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http://hawaii.eagle-i.net/i/0000012b-1c5f-99ef-06c2-9c7f80000000

Core facility that provides the following services: Training and advice for general imaging techniques, Histology processing service, Hematoxylin and eosin staining service, Training and advice for general histology techniques. This lab provides routine histology processing, specialized histochemical and immunohistological techniques, and access to several microscopic platforms. The core also provides technical assistance, training, and consultation in histological and imaging techniques to investigators throughout the University on a cost-recovery basis.

Proper citation: UH Manoa RCMI Histology and Imaging Core Facility (RRID:SCR_010109) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-c5d0-1c3d-a53f-a15a80000000

Core facility that provides the following services: Protein separation service, 2D gel production, Analysis of protein distribution of 2D gel, Standardized imaging of 2D gel, Mass spectrometry analysis service, Desalting, Trypsin Digestion. The mission of the UCC Biomedical Proteomic Facility is to accelerate discovery by giving UCC investigators access to cutting edge mass spectrometry are rapidly advancing and requires considerable technical expertise and expensive equipments. To keep UCC scientists competitive, new technologies will be incorporated into the facility as soon as possible to meet the needs. The facility is open to all investigators on collaboration or a fee-for-service basis. User fees will be adjusted depending on demand and to keep costs competitive.

Proper citation: UCC Biomedical Proteomic Facility (RRID:SCR_010073) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-aaee-9c0e-a272-8ee780000000

Core facility that provides the following services: HIV and HCV viral load extraction, Amplification and detection of HCV and HIV viral load, HIV-1 and HCV drug resistance genotyping, Neurotoxicity and neuroprotection assays, PBMC antiviral assay, MAGI antiviral assay, HIV-1 Tat inhibition assay, HIV p24 measurement service, Cytokine/Chemokine measurement, Hormone measurement, NF-kB expression induction assay, Detection of TH1, TH2, Treg, and TH17 cytokine profiles in T lymphocytes subsets, Immunophenotyping, intracellular cytokines/chemokines and apoptosis assay service, B and T cell immune activation, function, proliferation and differentiation assays, Macrophage function assay, Cell viability, cell proliferation and cytotoxicity, Cell cycle analysis, Inflammation and oxidative stress Calcium mobilization, kinase activation, and signal transduction, Gene expression service, Apoptosis test, In vivo/in vitro cytotoxicity measurement, Plaque and colony formation counting, Inflammation antibody array service, Apoptosis antibody array service, Angiogenesis antibody array, Protein and gene expression study, Standardized imaging of 2D gel. The laboratory supports research in the areas of HIV/AIDS and substances of abuse. Specialized facilities are made available to researchers for scientific studies in fields of immunology, drugs of abuse, HIV/AIDS and related infectious diseases. The core lab provides researchers with assays for nucleic acids detection, virus genotyping, flow cytometric phenotyping, lymphocyte proliferation, cytotoxic and non-cytotoxic activity, cytokine and chemokine determinations, and drugs of abuse quantification.

Proper citation: UCC HIV and Substance of Abuse Laboratory Core (RRID:SCR_010076) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-cb34-a797-a53f-a15a80000000

Core facility that provides the following services: Immunocytochemistry service. The immunocytochemistry laboratory specializes in the qualitative identification and localization of cells bearing selective markers by employing specific antibodies to these molecules.

Proper citation: UCC Immunocytochemistry Laboratory (RRID:SCR_010077) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-ca9b-b63c-a53f-a15a80000000

Core facility that provides the following services: Qualitative measure of neuronal death, Computerized image analysis. The goal of the facility is to assist UCC investigators in the use of cultured neurons, glias and organotypic cultures. The cultures are used for patch clamping after in vitro treatments with drugs of addiction or inhibitors and for in vitro models of neurodegenerative diseases. The core facility consists of a coordinator and a technician. Neuronal cultures are prepared from fetal cortex, hippocampus or astrocytes from cerebral cortex.

Proper citation: UCC Neuronal Glia Culture Facility (RRID:SCR_010078) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-2c98-3564-5b95-f21080000000

Core facility that provides the following services: Necropsy and tissue collection, Blood chemistries service, Bronchoalveolar lavage service, Cerebro-spinal tap service. The Animal Resources Center (ARC) is a part of the Unit of Comparative Medicine at the Medical Sciences Campus (MSC) of the University of Puerto Rico (UPR), committed to offer quality services to the university community and private entities, which through an accredited and properly regulated facility, and highly qualified personnel, provides care and maintenance of animals to be used in research.

Proper citation: UPR Animal Resources Center (RRID:SCR_010111) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-d046-71cb-a53f-a15a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. The facility offers microscope-based systems that allow the assessment of cellular responses, such as calcium signaling with fast temporal resolution. The facility offers 1) Confocal imaging services; 2) Brightfield, darkfield, phase contrast, Nomarski and epi-fluorescence imaging; 3) High spatial and temporal resolution imaging, 4) Collection of serial sections (Deconvolution capabilities) and 5) Morphometric analysis.

Proper citation: UCC Optical Imaging Facility (RRID:SCR_010079) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-3599-5885-2f73-b43980000000

Core facility that provides the following services: Construction and validation of random-sheared DNA fragment libraries, DNA sequencing (Sanger) service, 96-well plasmid preparation service, Genotyping/fragment analysis, BAC end sequencing, Plasmid library construction service, Genome sequencing project. The ASGPB genome infrastructure currently consists of several state-of-the-art capillary-based DNA sequencers and accessory equipment to deal with large sample volumes. The facility can process up to 9000 samples per day with a projected sequence output of 6.75 Million bases. Several prokaryotic and one eukaryotic genome project are currently in progress. The facility offers DNA sequencing services for a wide range of templates including plasmid DNA, PCR fragments, cosmid DNA, and Bacterial Artificial Chromosomes (BACs). Sequencing reactions are performed using Applied Biosystems BigDye terminator chemistry and are run on ABI 3730XL capillary-based DNA sequencers.

Proper citation: UH Manoa Sequencing Facility (RRID:SCR_010114) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-00bf-6765-9e37-5ded80000000

Core facility that provides the following services: Sequencing service, Genotyping service. We are a low cost, fee-for-service facility designed to provide students and researchers in Puerto Rico with access to state-of-the-art equipment for collecting sequence and genotype data. We offer full service sequencing (reaction set-up, clean up, run and delivery) and fragment analysis data generation and offer personalized support to our users.

Proper citation: UPR AABRE Program: Sequencing and Genotyping Facility (RRID:SCR_010118) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-f732-79cc-6bbe-6fcf80000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core aims to enhance biomedical research in Puerto Rico by providing resources for research, education and training. These resources will work to advance these specific aims: 1. enhance biomedical research in PR by providing researchers with the bioinformatics tools and technical support they require to perform cutting-edge biomedical research; 2. enhance the computational biology research environment in Puerto Rico by establishing research collaborations with biomedical, computational and mathematics researchers; 3. enhance multidisciplinary research by developing new courses and educational materials in computational biology, statistics and bioinformatics in collaboration with research faculty and the Science and Technology Competency Enhancement (STCE) Core; 4. enhance research by promoting advanced networking between PRAABRE member institutions, to enable collaborative research on and off the island; 5. enhance biomedical research by promoting effective access to scientific literature and databases for the biomedical researchers in PRAABRE; and 6. enhance biomedical research by enabling effective management of bibliographic information by fostering the use of bibliographic software and applying it to literature searches, articles and references management and manuscript writing.

Proper citation: University of Puerto Rico Biomedical Informatics Research Core (RRID:SCR_010119) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012f-0445-ea9e-1247-b2dc80000000

Core facility that provides the following services: MRI image analysis service, MRI image processing service.

Proper citation: UH Manoa Hawaii Center for AIDS Imaging Analysis Core (RRID:SCR_010083) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2510-69a9-c99c-aef680000000

A 2000 square foot BSL-3 facility located at the University of Hawaii, JABSOM.

Proper citation: UH Manoa BSL-3 Containment Facility (RRID:SCR_010086) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-469c-06c2-9c7f80000000

Core facility that provides the following services: Scanning electron microscopy service, Conventional and energy-filtering transmission electron microscopy service, Laser scanning confocal microscopy service, Fluorescence microscopy service, Laser microdissection and laser tweezing service. The Biological Electron Microscope Facility (BEMF) at the University of Hawai''i is a multi-user/service facility, administered by the Pacific Biosciences Research Center (PBRC). The mission of the BEMF is to provide biological-biomedical researchers with state-of-the-art instrumentation, training and services for high-resolution scanning electron microscopy, conventional and energy-filtering transmission electron microscopy, optical, fluorescence, and laser scanning confocal microscopy, and image analysis on a recharge basis. The facility receives partial support from the Pacific Biosciences Research Center and the UH Manoa Chancellor''s Office. Includes the Richard Allen Image Collection, a unique set of images taken with electron microscopes (http://www5.pbrc.hawaii.edu/allen/).

Proper citation: UH Manoa Biological Electron Microscope Facility (RRID:SCR_010087) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012d-1479-c6f4-bc92-16e380000000

Cayo Santiago is one of the world''s most renowned field sites for short term and longitudinal non-human primate studies. Its unique research value consists of:a stable and minimally disrupted long-term population management policy which allows investigators to plan and conduct longitudinal studies, an extensive and detailed computerized demographic database on the colony that provides information on individuals dating back to 1957, and DNA fingerprinting which is applied to confirm maternal and paternal relatedness of individuals.

Proper citation: UPR Cayo Santiago Caribbean Primate Research Center (RRID:SCR_010120) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-b257-d364-2f73-b43980000000

The Biostatistics Shared Resource (BSR) provides statistical consultation and support to the research enterprise of the University of Hawai?i Cancer Center. The primary goal of the resource is to improve the quality of the research through sound statistical principles. The resource was established in 1995 and provides access to statistical support to all Center members on all aspects of research. The BSR provides short-term as well as long-term support for research projects. Support is provided to scientists in epidemiology, health behavior and quality of life research, and molecular and clinical oncology. The members of the Shared Resource often serve as co-investigators on epidemiology and cancer prevention and control projects. Consultation is available in the following areas: design, data collection, data analysis, statistical programming, interpretation and dissemination of results, and protocol review. The members of the resource have contributed to the publication of many peer-reviewed manuscripts from Center research projects. In addition, the statisticians work on methodological issues important to the research ongoing at UH Cancer Center. One area of interest is measurement error models that correct for bias in model parameter estimates when the exposure variable is measured with error. The role of dietary intake and sunlight exposure in cancer etiology are of interest at the Center, and these variables are measured with error. Another interest is in how susceptibility genes affect cancer risk, in combination with exposure data. Therefore, statistical techniques for the investigation of genes and lifestyle-gene interactions in cancer models are also studied.

Proper citation: UH Manoa Biostatistics Shared Resources (RRID:SCR_010088) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-0387-c99c-aef680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides access to high speed computer hardware and bioinformatics consultation. Research at the facility includes studying of evolutionary change in emergent dengue viruses associated with increasingly severe epidemics and confirm the impact of these changes in experimental models.

Proper citation: University of Hawaii at Manoa Centers of Biomedical Research Excellence Bioinformatics Core Facility (RRID:SCR_010089) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250a-2ace-43fb-601a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Oligonucleotide synthesis service, Automated DNA sequencing, Genotyping analysis service, Analysis of DNA, RNA or proteins, Microarray service. The long-term goal of the Center for Genomics in Health Disparities and Rare Diseases (CGHDRD) is to provide the critical environment that will enable high quality translational and biomedical research in pharmacogenomics, human genetics and genomics, molecular biology. We aim to develop and strengthen a collaborative research environment by providing research infrastructure that supports the focal areas of research at the University of Puerto Rico Medical Sciences Campus (UPR-MSC), which encompass common diseases such as cancer, neurological and cardiovascular disorders as well as rare disorders, by improving the human and physical resources. The Center focuses these initiatives on externally funded, interdisciplinary, collaborative projects which enhance the quality of translational, biomedical and clinical research at the Medical Sciences Campus linked to health disparities and rare disorders in Puerto Rico and nationally. Collaborations with researchers at institutions outside of Puerto Rico or other RCMI institutions, as well as other academic units in the island and in the UPR system are encouraged. The Center provides the necessary expertise to apply high throughput genotyping, expression profiling and sequencing technologies at the UPR-MSC. Specialized technical staff trains researchers at different levels of their scientific careers in supported technologies. Novel DNA and RNA isolation methodologies are applied to a diverse group of organisms and biological samples for nucleic acids sequence analysis in general.

Proper citation: UPR Center for Genomics in Health Disparities and Rare Disorders (RRID:SCR_010122) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-e488-f75c-a272-8ee780000000

Core facility that provides the following services: Nucleic acid sequencing service, Real-Time PCR services, Cell culture service, Protein quantitation assay, Nucleic acid estimation service, Fusion protein purification and expression service, Transfection service, Site-directed mutagenesis service, Primer design service, Gel electrophoresis service, Polymerase chain reaction service. The Protein and Nucleic Acid Core Facility (PNACF) aids in the transition from classical to molecular analysis of the problems being addressed by faculty members. PNACF focuses on faculty training, seminars, training on specialized molecular biology techniques, protein expression and protein purification and characterization.

Proper citation: UCC Protein and Nucleic Acid Core Facility (RRID:SCR_010080) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-36a1-152c-2f73-b43980000000

Core facility that provides the following services: Solid state studies service.

Proper citation: UH Manoa NMR Lab (RRID:SCR_010082) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000134-ed9a-ccf6-77e4-a45080000000

The Major Instrumentation Core has been established to provide technical services and consumable supplies necessary for the operation and maintenance of a variety of major instruments that support biomedical research at Xavier University. The long term goal of the Major Instrumentation Core is to enhance the overall biomedical research capabilities at Xavier University by making available essential instrument-based platforms for various research projects. To achieve this goal the Major Instrumentation Core has set the following specific aims: 1). support biomedical research projects on campus by providing essential analytical instrumentation, 2). maintain and operate existing instruments, 3). acquire new instruments, and 4). provide technical support for user community of the core.

Proper citation: XULA Major Instrumentation Core (RRID:SCR_010209) Copy   

•   Source: SciCrunch Registry