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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Lasker Foundation
 
Resource Report
Resource Website
1+ mentions
Lasker Foundation (RRID:SCR_005114) Lasker Foundation institution The Albert and Mary Lasker Foundation and its programs are dedicated to the support of biomedical research toward conquering disease, improving human health and extending life. The Foundation''s mission is to foster the prevention and treatment of disease and disabilities by honoring excellence in basic and clinical science, by educating the public, and by advocating for support of medical research. The Lasker Awards The Lasker Foundation''s Awards Program recognizes the contributions of scientists, physicians, and public servants who have made major advances in the understanding, diagnosis, treatment, cure or prevention of human disease. Other Programs Although the Lasker Foundation is not a grant-giving organization, it does support select initiatives that raise awareness of medical discoveries and their benefits to human health, and that increase support for the medical science enterprise. These initiatives have included study groups, Congressional briefings, innovative web-based programs, educational forums, and scholarly studies. biomedical, award, research, basic science, clinical science ISNI: 0000 0000 9598 7178, nlx_144121, Crossref funder ID: 100009577, grid.480586.7 https://ror.org/05fcw6535 SCR_005114 Albert and Mary Lasker Foundation, Albert Mary Lasker Foundation 2026-02-14 02:00:51 2
IsoformEx
 
Resource Report
Resource Website
1+ mentions
IsoformEx (RRID:SCR_005235) software resource Software that estimates transcript expression levels and gene expression levels from mRNA-Seq data. Technically speaking, IsoformEx parses bowtie alignment files in a project directory (e.g. ~yourid/isoformex/xxx, where xxx is the project name) and generates two files: (1) xxx/xxx_transcript_1.txt: expression levels of all transcripts, (2) xxx/xxx_gene_1.txt: expression levels of all genes. is listed by: OMICtools
has parent organization: University of Pennsylvania; Philadelphia; USA
Free for academic use, Commercial use with permission OMICS_01260 SCR_005235 IsoformEx: Isoform level gene expression estimation using non-negative least squares from mRNA-Seq data 2026-02-14 02:00:53 2
BioPortfolio
 
Resource Report
Resource Website
1+ mentions
BioPortfolio (RRID:SCR_005230) BioPortfolio job resource, blog, portal, data or information resource, narrative resource, database BioPortfolio is a leading news, information and knowledge resource covering the global life science industries impacted on by biotechnology. The site aims to provide the lay person, the researcher and the management executive with a single location to source core information on specific bio-related topics, to collate relevant data associated with each topic and to point the user to relevant knowledge resources. We publish up to the minute news (see biotechnology news categories) and regularly update content across our information databases. BioPortfolio promotes and sells market research and management reports from 30+ publishers. In addition our unique corporate database lists 40,000+ companies and organizations. BioPortfolio aims to bring together high quality information about marketed drugs - medication and relevant clinical trials, research papers and recent news from PubMed, ClinicalTrials.gov, and DailyMed. Additionally, resources include biotech, pharma and medical job listings. When the BioPortfolio site was launched in February 1997 the company aimed to provide a global free-to-use resource with defined aims and mission statement: to meet the increasing demand of consumers, scientists, investors, commerce and government for timely, accurate and commercially useful information and intelligence on biotechnology companies, technologies and products world-wide. Driven by the success of the site we have made major investments and improvements to enhance our content and to apply the latest web technologies to improve functionality and site utility. We believe this unique depth and breadth of content is supporting individuals, organizations and policy-makers to become more aware of the role of biotechnology on the global economy. With 97,000 users visiting the site more than once per month we are confident that we are providing information our users need. We hope you the users find the site of value for both personal and professional reasons. Please enjoy this free resource and email your comments! news, information, knowledge, life science, biotechnology, pubmed, corporate, clinical trial, drug, career, pharmaceutical, healthcare, medicine, clinical, industry is used by: NIF Data Federation
is used by: Integrated Blogs
For personal non-commercial use only nlx_144235 SCR_005230 2026-02-14 02:01:05 1
aldex
 
Resource Report
Resource Website
10+ mentions
aldex (RRID:SCR_005110) aldex software resource RNA-seq tool that uses the Dirichlet distribution and a transformation to identify genes that exhibit small within-condition and large between-condition variance. transcriptome, meta-transcriptome is listed by: OMICtools
is related to: ALDEx2
GNU General Public License, v3 OMICS_01297 SCR_005110 aldex: ANOVA-like RNA-seq analysis 2026-02-14 02:00:51 12
ABSOLUTE
 
Resource Report
Resource Website
100+ mentions
ABSOLUTE (RRID:SCR_005198) ABSOLUTE software resource Software to estimate purity / ploidy, and from that compute absolute copy-number and mutation multiplicities. When DNA is extracted from an admixed population of cancer and normal cells, the information on absolute copy number per cancer cell is lost in the mixing. The purpose of ABSOLUTE is to re-extract these data from the mixed DNA population. This process begins by generation of segmented copy number data, which is input to the ABSOLUTE algorithm together with pre-computed models of recurrent cancer karyotypes and, optionally, allelic fraction values for somatic point mutations. The output of ABSOLUTE then provides re-extracted information on the absolute cellular copy number of local DNA segments and, for point mutations, the number of mutated alleles. is listed by: OMICtools
has parent organization: Broad Institute
Cancer, Normal PMID:22544022 Account required OMICS_00217 SCR_005198 2026-02-14 02:01:03 263
VARIANT
 
Resource Report
Resource Website
1000+ mentions
VARIANT (RRID:SCR_005194) VARIANT data processing software, data analysis service, analysis service resource, data analysis software, production service resource, service resource, software application, software resource Analysis tool that can report the functional properties of any variant in all the human, mouse or rat genes (and soon new model organisms will be added) and the corresponding neighborhoods. Also other non-coding extra-genic regions, such as miRNAs are included in the analysis. It not only reports the obvious functional effects in the coding regions but also analyzes noncoding SNVs situated both within the gene and in the neighborhood that could affect different regulatory motifs, splicing signals, and other structural elements. These include: Jaspar regulatory motifs, miRNA targets, splice sites, exonic splicing silencers, calculations of selective pressures on the particular polymorphic positions, etc. Software analysis pipelines used in the analysis of NGS data are highly modular, heterogeneous, and rapidly evolving. VARIANT can easily be incorporated into a NGS resequencing pipeline either as a CLI or invoked a webservice. It inputs data directly from the most widely used programs for SNV detection., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. functional property, variant, gene, non-coding region, mirna, function, single nucleotide variant, next generation sequencing, command line is listed by: OMICtools
has parent organization: Principe Felipe Research Centre; Valencia; Spain
Spanish Ministry of Science and Innovation BIO2011-27069 PMID:22693211 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00193 SCR_005194 Variant effect, VARIant ANalysis Tool 2026-02-14 02:00:50 1366
SNPdbe
 
Resource Report
Resource Website
1+ mentions
SNPdbe (RRID:SCR_005190) SNPdbe data repository, storage service resource, data or information resource, service resource, database A database to fill the annotation gap left by the high cost of experimental testing for functional significance of protein variants. It joins related bits of knowledge, currently distributed throughout various databases, into a consistent, easily accessible, and updatable resource. It currently covers over 155,000 protein sequences which come from more than 2,600 organisms. Overall more than one million single amino acid substitutions (SAASs) are referenced consisting of natural variants, SAASs from mutagenesis experiments and sequencing conflicts. SNPdbe offers the following pieces of information (if available) on each SAAS: * Experimentally derived functional and structural impact * Predicted functional effect * Associated disease * Average heterozygosity * Experimental evidence of the nsSNP * Evolutionary conservation of wildtype and mutant amino acid * Link-outs to external databases A convenient webinterface to query SAASs on the following levels is offered: * Protein and gene identifiers and keywords * Disease keywords * Protein sequence on different sequence identity thresholds * Variant identifier (dbSNP rs, SwissVar, PMD) or specific mutant like XposY and specified sequence They offer the possibility to submit protein sequences along with experimentally substantiated mutations in order to predict their functional effect and inclusion into our database. single amino acid substitution, protein variant, protein, variant, protein sequence, natural variant, mutagenesis, sequencing, mutation is listed by: OMICtools
has parent organization: ROSTLAB
PMID:22210871 Free for academic use, Non-commercial, Commercial use with permission, The community can contribute to this resource OMICS_00185 SCR_005190 SNPdbe - nsSNP database of functional effects, nsSNP database of functional effects 2026-02-14 02:00:52 4
CTSAconnect
 
Resource Report
Resource Website
CTSAconnect (RRID:SCR_005225) CTSAconnect ontology, knowledge environment, data or information resource, source code, service resource, controlled vocabulary, software resource, narrative resource, standard specification THIS RESOURCE IS NO LONGER IS SERVICE. Documented on December 5th, 2022. Semantic framework to integrate information about research activities, clinical activities, and scientific resources to facilitate the production and consumption of Linked Open Data about investigators, physicians, biomedical research resources, services, and clinical activities. The goal is to enable software to consume data from multiple sources and allow the broadest possible representation of researchers'''' and clinicians'''' activities and research products. Current research tracking and networking systems rely largely on publications, but clinical encounters, reagents, techniques, specimens, model organisms, etc., are equally valuable for representing expertise. CTSAConnect will provide linkage between semantic representations of a wide range of clinical and research data using controlled vocabularies mapped to the Unified Medical Language System (UMLS) as a bridge between the two subject areas. The data sources include data from Medicaid, hospital billing systems, CTSAShareCenter, and other CTSA resource data, eagle-i and VIVO. It allows institutions to leverage existing tools and data sources by making the information they contain more discoverable and easier to integrate. For instance, with the ISF, researchers can be characterized by organizational affiliations, grant and project participation, research resources that they have generated, and publications that they have (co)-authored. Clinicians can be characterized by training and credentials, by clinical research topic, and by the kinds of procedures and specialization that can be inferred from encounter data. LOD refers to data that has been given a specific Uniform Resource Identifier (URI), for the purpose of sharing and linking data and information on the Semantic Web. While a large amount of data is published as LOD, there remains a significant gap in the representation of research resources and clinical expertise. Researchers can be characterized by the organization to which they belong, the grants and research in which they have participated, the research topics and research resources (reagents, biospecimens, animal models) they have generated, as well as the publications they have (co)-authored. Clinician profiles on the other hand, can be defined by their credentials, clinical research topics, and the kinds of procedures and specialization that can be inferred from clinical encounter data. They believe that integrating and relating this diversity of information sources and platforms requires addressing the overlap between research resources and the attributes and activities of researchers and clinicians. CTSAconnect aims to promote integration and discovery of research activities, resources, and clinical expertise. To this end, they will publish their ontologies and LOD via their website, which will also illustrate repeatable methods and examples of how to extract, consume, and utilize this valuable new LOD using freely available tools like VIVO, eagle-i, and Google APIs. CTSAconnect is a collaboration between Oregon Health & Science University, Stony Brook University, Cornell University, Harvard University, University at Buffalo, and the University of Florida, and leverages the work of eagle-i (eagle-i.net), VIVO (vivoweb.org), and ShareCenter (ctsasharecenter.org). data sharing, clinical, research, semantic framework, linked open data, collaborate is related to: Eagle I
is related to: VIVO
is related to: CTSA ShareCenter
is related to: Clinical and Translational Science Awards Consortium
is related to: CTSA ShareCenter
has parent organization: Oregon Health and Science University; Oregon; USA
has parent organization: Harvard University; Cambridge; United States
Booz Allen Hamilton ;
National Center for Advancing Translational Sciences
THIS RESOURCE IS NO LONGER IS SERVICE nlx_144228 SCR_005225 CTSAconnect: A Linked Open Data approach to represent clinical and research expertise activities and resources, CTSA Connect, Clinical and Translational Science Awards Connect 2026-02-14 02:01:05 0
qSNP
 
Resource Report
Resource Website
10+ mentions
qSNP (RRID:SCR_005105) qSNP software resource A single nucleotide variant caller optimised for identifying somatic variants in low cellularity cancer samples. is listed by: OMICtools
has parent organization: University of Queensland; Brisbane; Australia
Cancer PMID:24250782 OMICS_00089 SCR_005105 2026-02-14 02:00:51 24
Damon Runyon Cancer Research Foundation
 
Resource Report
Resource Website
50+ mentions
Damon Runyon Cancer Research Foundation (RRID:SCR_005106) Damon Runyon Foundation institution The Damon Runyon Cancer Research Foundation funds early career cancer researchers who have the energy, drive and creativity to become leading innovators in their fields. We identify the best young scientists in the nation and support them through four award programs: our Fellowship, Pediatric Cancer Fellowship, Clinical Investigator and Innovation Awards. Damon Runyon awards give young scientists: * Freedom to follow their own ideas, explore new paths and take risks * A prestigious endorsement that attracts further funding, advances their careers and accelerates their research * Guaranteed financial support, sparing them hours applying for grants Since 1946, Damon Runyon has invested more than $240 million in the best young minds in the nation. Our alumni include 11 Nobel Laureates and leaders of major cancer centers across the United States. Many of our 3,300 scientists have gone on to make breakthroughs in the way we prevent, diagnose and treat many forms of cancer. The Damon Runyon Cancer Research Foundation is a registered nonprofit with 501(c)(3) status. fellowship, grant, cancer Crossref funder ID: 100001021, grid.453008.a, ISNI: 0000 0004 0508 2172, nlx_144117 https://ror.org/01gd7b947 SCR_005106 2026-02-14 02:01:04 63
SAMtools/BCFtools
 
Resource Report
Resource Website
500+ mentions
SAMtools/BCFtools (RRID:SCR_005227) BCFtools software resource Provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format. snp, indel, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SAMTOOLS
DOI:10.1101/090811 biotools:bcftools, OMICS_13458 https://bio.tools/bcftools
https://sources.debian.org/src/bcftools/
SCR_005227 2026-02-14 02:01:04 904
MiTie
 
Resource Report
Resource Website
1+ mentions
MiTie (RRID:SCR_005228) MiTie software resource Software framework for simultaneous RNA-Seq-based Transcript Identification and Quantification in Multiple Samples. They define a likelihood function based on the negative binomial distribution, use a regularization approach to select a few transcripts collectively explaining the observed read data, and show how to find the optimal solution using Mixed Integer Programming. MiTie can a) take advantage of known transcripts, b) reconstruct and quantify transcripts simultaneously in multiple samples, as well as c) resolve the location of multi-mapping reads. It is designed for genome- and assembly-based transcriptome reconstruction. c++, rna-seq, transcript is listed by: OMICtools OMICS_01279 SCR_005228 MiTie: Simultaneous RNA-Seq-based Transcript Identification and Quantification in Multiple Samples 2026-02-14 02:00:53 4
ORMAN
 
Resource Report
Resource Website
1+ mentions
ORMAN (RRID:SCR_005188) ORMAN software resource A software tool for resolving multi-mappings within an RNA-Seq SAM file. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24130305 OMICS_01284, biotools:orman https://bio.tools/orman SCR_005188 ORMAN : Optimal Resolution of Ambiguous RNA-Seq Multi-mappings in the Presence of Novel Isoforms 2026-02-14 02:00:50 4
FRCbam
 
Resource Report
Resource Website
10+ mentions
FRCbam (RRID:SCR_005189) software resource Software package containing tools to process bam files in order to evaluate and analyze de novo assembly / assemblers and identify Structural Variations suspicious genomics regions. The tools have been already successfully applied in several de novo and resequencing projects. This package contains two tools: # FRCbam: tool to compute Feature Response Curves in order to validate and rank assemblies and assemblers # FindTranslocations: tool to identify chromosomal rearrangements using Mate Pairs standalone software, sam, bam is listed by: OMICtools PMID:23284938 GNU General Public License, v3 OMICS_04070 SCR_005189 2026-02-14 02:01:03 11
University of KwaZulu-Natal; Durban; South Africa
 
Resource Report
Resource Website
1+ mentions
University of KwaZulu-Natal; Durban; South Africa (RRID:SCR_005222) UKZN university University with five campuses in the province of KwaZulu-Natal in South Africa. It was formed on 1 January 2004 after the merger between the University of Natal and the University of Durban-Westville. is parent organization of: Africa Centre Biobank
is parent organization of: BioAfrica HIV Informatics in Africa
is parent organization of: Africa Centre for Health and Population Studies
nlx_51412, ISNI:0000 0001 0723 4123, Wikidata:Q727516, grid.16463.36, Crossref funder ID:501100004695 https://ror.org/04qzfn040 SCR_005222 University of KwaZulu-Natal, University of KwaZulu Natal 2026-02-14 02:01:03 3
SeqAnt
 
Resource Report
Resource Website
1+ mentions
SeqAnt (RRID:SCR_005186) SeqAnt data analysis service, analysis service resource, production service resource, service resource, software resource A free web service and open source software package that performs rapid, automated annotation of DNA sequence variants (single base mutations, insertions, deletions) discovered with any sequencing platform. Variant sites are characterized with respect to their functional type (Silent, Replacement, 5' UTR, 3' UTR, Intronic, Intergenic), whether they have been previously submitted to dbSNP, and their evolutionary conservation. Annotated variants can be viewed directly on the web browser, downloaded in a tab delimited text file, or directly uploaded in a Browser Extended Data (BED) format to the UCSC genome browser. SeqAnt further identifies all loci harboring two or more coding sequence variants that help investigators identify potential compound heterozygous loci within exome sequencing experiments. In total, SeqAnt resolves a significant bottleneck by allowing an investigator to rapidly prioritize the functional analysis of those variants of interest. annotation, dna sequence variant, single base mutation, insertion, deletion, sequencing, mutation, variant, sequence variant, perl, sequence, genome is listed by: OMICtools
has parent organization: Emory University; Georgia; USA
has parent organization: SourceForge
PMID:20854673 GNU General Public License, v2 OMICS_00182 SCR_005186 SeqAnt - Sequence Annotator 2026-02-14 02:00:52 2
NGS-SNP
 
Resource Report
Resource Website
10+ mentions
NGS-SNP (RRID:SCR_005182) NGS-SNP software resource A collection of command-line scripts for providing rich annotations for SNPs identified by the sequencing of transcripts or whole genomes from organisms with reference sequences in Ensembl. Included among the annotations, several of which are not available from any existing SNP annotation tools, are the results of detailed comparisons with orthologous sequences. These comparisons allow, for example, SNPs to be sorted or filtered based on how drastically the SNP changes the score of a protein alignment. Other fields indicate the names of overlapping protein domains or features, and the conservation of both the SNP site and flanking regions. NCBI, Ensembl, and Uniprot IDs are provided for genes, transcripts, and proteins when applicable, along with Gene Ontology terms, a gene description, phenotypes linked to the gene, and an indication of whether the SNP is novel or known. A ?Model_Annotations? field provides several annotations obtained by transferring in silico the SNP to an orthologous gene, typically in a well-characterized species. annotation, snp, sequencing, transcript, genome, reference sequence, indel, annotate, reference chromosome, reference transcript, gene, command-line is listed by: OMICtools
is related to: Ensembl
has parent organization: University of Alberta; Alberta; Canada
OMICS_00177 SCR_005182 2026-02-14 02:00:50 32
SeqBuster
 
Resource Report
Resource Website
10+ mentions
SeqBuster (RRID:SCR_009616) data analysis software, software resource, data processing software, software application Software tool for processing and analysis of small RNAs datasets.Reveals ubiquitous miRNA modifications in human embryonic cells. small RNAs datasets, ubiquitous miRNA modifications, human embryonic cells, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Spanish Ministry of Health ;
CIBERESP ;
Sixth Framework Programme of the European Commission ;
Spanish Ministry of Science and Innovation
PMID:20008100 Free, Available for download, Freely available OMICS_00367, biotools:seqbuster https://bio.tools/seqbuster SCR_009616 2026-02-14 02:01:53 30
Fiber Optic Button Response System
 
Resource Report
Resource Website
10+ mentions
Fiber Optic Button Response System (RRID:SCR_009577) instrument resource Instrument that accurately gathers participant responses and verifies signals. The Celeritas Series response units are assembled using high-impact, chemical resistant, medical grade plastic. The response units include a tactile indicator to ensure correct finger placement during experiments and comfortably attach to the participant?s wrists. The units communicate button presses through fiber optic cabling which connects to a Fiber Optic Interface Console located in the control room through an available wave guide. The interface console provides real-time feedback of participant responses via LED indicators and includes a set of switches which can be used to make responses for the participant as needed. eeg, meg, electrocorticography, experiment control, hardware, magnetic resonance, response monitoring, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) nlx_155759 http://www.nitrc.org/projects/fobrs
https://pstnet.com/wp-content/uploads/2021/04/Celeritas-Operator-Manual.pdf
SCR_009577 Celeritas Fiber Optic Response System 2026-02-14 02:01:52 22
Oregon State University; Oregon; USA
 
Resource Report
Resource Website
1+ mentions
Oregon State University; Oregon; USA (RRID:SCR_009731) university Public research university in Corvallis, Oregon. The university currently offers more than 200 undergraduate-degree programs along with a variety of graduate and doctoral degrees. is parent organization of: TileQC
is parent organization of: AFTOL
is parent organization of: CASHX
is parent organization of: Chromaseq
is parent organization of: Plant Ontology
is parent organization of: Plant Ontology
is parent organization of: Northern Spalting - Applied Mycology Lab
is parent organization of: EnVision Manager
is parent organization of: Oregon State University Center for Quantitative Life Sciences Core Facility
is parent organization of: Oregon State University Electron Microscopy Core Facility
Wikidata:Q861888, ISNI:0000 0001 2112 1969, Crossref funder ID:100009612, nlx_87751, grid.4391.f https://ror.org/00ysfqy60 SCR_009731 2026-02-14 02:01:54 1

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