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https://www.med.upenn.edu/cbica/cubic.html

Linux based High Performance Computing resource available to faculty conducting research related to medical imaging and informatics. There are over 150 compute nodes with more than 5000 Intel Xeon CPUs and 58TB of RAM, over 100 GPUs, and 600TB of storage in the cluster. Facility management structure is designed to encourage data sharing and use of common software on this powerful resource, particularly in development of new software and application of imaging to new domains.

Proper citation: University of Pennsylvania Perelman School of Medicine CUBIC (HPC Cluster) (RRID:SCR_022406) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/idom/drc/cores/ria.html

Core offers immunoassay, metabolite, and HPLC services to basic, translational, and clinical investigators performing diabetes and related metabolic disease research.RIA /Biomarkers Core is located on the 12th floor of Smilow Center for Translational Research.Approximately 100 different diabetes, obesity and metabolism-related biomarkers from multiple species including human can be assayed using radioimmunoassay (RIA), enzyme-linked immunosorbent assay (ELISA, both absorbance and fluorometric), multiplex ELISA on the Luminex platform, and enzymatic and HPLC methods for an expanding variety of diabetes and metabolism related metabolites, hormones, catecholamines and cytokines derived from blood, urine, and tissue samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Radioimmunoassay and Biomarkers Core Facility (RRID:SCR_022405) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/bmic/

Supports next generation infrastructure for clinical data storage and management, next generation analytics, next generation infrastructure for support of clinical research including new clinical trials management system and software, next generation infrastructure for centralizing and integrating external sources of data such as genomics data. Enables future clinical and translational research through biomedical informatics education and training targeted at graduate students, postdoctoral students, residents, fellows, as well as faculty across the biomedical research spectrum.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for BioMedical Informatics Core Facility (RRID:SCR_022401) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cpob/biostatistical-consulting.html

Service supports consultation and collaboration in areas of biostatistics and epidemiology to Penn vision scientists. Biostatisticians and data management experts provide advice on study design, and offer services in sample size determinations, data management, data analysis, data interpretation, and data presentation. They are active participants in the development and writing of grant applications and manuscripts.Consulting personnel are CPOB members. In addition to their methodological and technical expertise, consultants are knowledgeable about ocular conditions under study in Penn vision community, about commonly used measures that are unique to vision research (visual acuity, refractive error, visual field indices, etc) and specialized statistical analysis techniques required for many experimental designs used in vision research (correlated data techniques to handle appropriately data from two eyes of same subject). Majority of projects are patient oriented researchers,however, CPOB Consulting Service also works on data analysis with bench laboratory scientists.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Preventive Ophthalmology and Biostatistics Biostatistical Consulting Core Facility (RRID:SCR_022400) Copy   

•   Source: SciCrunch Registry

https://ibicic.med.upenn.edu/

Core assists faculty, staff, and students with conducting research projects using electronic health record data.Facilitates access to clinical data and performs data analysis using artificial intelligence, ontologies, natural language processing, machine learning, and visual analytics. Provides innovative research services by applying data science to clinical data in order to learn actionable healthcare knowledge and develop impactful solutions for improving patient care. Services include facilitating access to Penn Medicine clinical data resources, performing data analysis using diverse computational methods, and providing tools for exploratory data analysis/visualize with priority access to the IBI Idea Factory for immersive display of data and research results. �

Proper citation: University of Pennsylvania Perelman School of Medicine IBI Clinical Research Informatics Core Facility (RRID:SCR_022409) Copy   

•   Source: SciCrunch Registry

https://pathbio.med.upenn.edu/hic/site/

Core provides wet bench expertise and infrastructure support for early phase�clinical trials and other investigations. Offers purified cell subsets from healthy human apheresis donors. �HIC staff are qualified to�perform blood (PBMC)�and tissue processing for viable cryopreservation following validated�standard operating procedures. Offers�range of immunological assays including digital ELISA, ELISA, ELISPOT, Luminex, flow cytometry and immune repertoire profiling (NGS of BCR and TCR rearrangements in bulk and single cell formats).Offers investigators expertise and guidance in clinical trial sample processing, regulatory compliance, immunology assay design and validation, data analysis and grant writing support.

Proper citation: University of Pennsylvania Perelman School of Medicine Human Immunology Core Facility (RRID:SCR_022380) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CMSDLD/the-molecular-pathology-and-imaging-core-mpic.html

Provides histological services, equipment, and technical expertise for processing and analyses of digestive, pancreatic, and liver tissues as well as three dimensional tissue culture models.�Part of the Center for Molecular Studies in Digestive and Liver Diseases

Proper citation: University of Pennsylvania Perelman School of Medicine Molecular Pathology and Imaging Core (MPIC) (RRID:SCR_022420) Copy   

•   Source: SciCrunch Registry

https://med-upenn.corefacilities.org/service_center/4311/?tab=requests

Our core, which is part of the PennCHOP Microbiome Program, provides access for researchers to small experimental isolators for variety of in vivo studies using germ free mice. Core personnel provide technical support for germ-free experiments. New addition to core is state-of-the-art Isocage system.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Gnotobiotic Mouse Core Facility (RRID:SCR_022384) Copy   

•   Source: SciCrunch Registry

https://ngsc.med.upenn.edu/#/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 10,2025. Core provides services related to single cell and bulk whole genome, RNA-Seq, ATAC-Seq, BIS-Seq, Exome-Seq, ChIP-Seq, CLIP-Seq, etc.Provides Illumina NovaSeq 6000 in addition to NextSeq and MiSeq sequencers - which all feature self-service as well as full-service operation. Offers experience with difficult, low input samples as well as sequencing and analyzing novel library types. Small Oxford Nanopore sequencer allows for full-length RNA or cDNA sequencing as well as very long read (100KB) sequencing from genomes. Offers experimental design services prior to starting your experiment.

Proper citation: University of Pennsylvania Perelman School of Medicine Next Generation Sequencing Core Facility (RRID:SCR_022382) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cvi/metabolomics-core.html

Core is overseen by Cardiovascular Institute and is partnership with the Abramson Cancer Center and the Institute for Diabetes, Obesity and Metabolism at Penn. Provides expertise in targeted and untargeted metabolomics of biological samples using liquid chromatography/mass spectrometry. Performs assays and assists in interpretation of results.

Proper citation: University of Pennsylvania Perelman School of Medicine Metabolomics Core Facility (RRID:SCR_022381) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cores/assets/user-content/documents/HTSC_overview_27May2015.pdf

Core provides distribution of lentivirus based shRNA and cDNA plasmid DNA clones; technical expertise in developing biological assays (i.e. biochemical-, cell-, and high-content) in miniaturized, multiwell microtiter plates that are laboratory automation compatible; high-throughput chemical and functional genomic screening, including data analysis and interpretation. Our goal is to use cutting biological models to discover genes and small molecules that enable scientists to further study functions of poorly understood proteins, signaling pathways, and cells in complex biological process relevant to human physiology and disease.

Proper citation: University of Pennsylvania Perelman School of Medicine High Throughput Screening Core Facility (RRID:SCR_022379) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-microbiome-human-intervention-core

Offers services to assist with design and implementation of microbiome studies.Assist with longitudinal studies as well as pilot studies.� Pilot studies can be rapidly implemented with human intervention core staff, project managers and research coordinators.

Proper citation: University of Pennsylvania Perelman School of Medicine Human Intervention Core Facility (RRID:SCR_022412) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/idom/drc/cores/cellbio.html

Provides support including experimental design, islet isolation, and performance of and/or training in range of assays for physiological, metabolic, and morphometric assessment of pancreatic islets as wells as many other tissues and cell types. Offers islet isolation and culture, free intracellular calcium ion measurements, quantitative oxygen consumption of pancreatic islets, electrode based closed cell respirometry, and access to Agilent�s� Seahorse Extracellular Flux Analyzer XFe96.

Proper citation: University of Pennsylvania Perelman School of Medicine Pancreatic Islet Cell Biology Core Facility (RRID:SCR_022411) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cvi/mouse-cardiovascular-phenotyping-core.html

Core provides services to assess cardiovascular function in mouse models and to provide validated surgical models of heart and vascular disease in mice to assess genetic or therapeutic interventions. Works with investigators to design and implement study along with any associated grant applications, animal protocol submissions and manuscript preparation. While central focus of facility is cardiovascular research, techniques employed are often useful to investigators in other fields. Helps to assess your needs and provide necessary technical training and scientific assistance in animal protocol preparation. Core runs on a fee for service model.�Accordingly, investigators will be responsible for costs incurred for their projects and prior animal protocol approval by Penn IACUC., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Mouse Cardiovascular Phenotyping Core Facility (RRID:SCR_022419) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/camri/index.html

Provides research MRI capabilities for investigators at UNMC and across greater Omaha area. Housed in Hixson-Lied Center, CAMRI operates Siemens 3T Prisma MRI instrument that can collect high quality data of any MR modality using advanced gradients and research grade pulse sequences. Variety of head coils (20-, 32-, and 64-channel) are available to optimize data collection for needs of specific studies. Studies incorporating functional MRI can take advantage of CAMRI�s suite of MRI-compatible response devices, mirrored 32-inch LCD screen, and integrated stimulus display computer.

Proper citation: University of Nebraska Medical Center Advanced Magnetic Resonance Imaging Core Facility (RRID:SCR_022468) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/confocal-microscopy/index.html

Facility houses imaging technologies ranging from super resolution (~ 0.120 um to 0.020 um) to microscopic (~ 0.300 um) to mesoscopic (~ 1 um) biomedical imaging. Imaging specialists provide training and/or actively assist researchers collecting images across imaging instrumentation. Instrumentation includes Zeiss ELYRA PS.1 is inverted microscope for super resolution (SR) structured illumination microscopy (SIM) and single molecule localization microscopy (SMLM) including, PhotoActivated Localization Microscopy (PALM) using photo switchable/convertible fluorescent proteins, Total Internal Reflection Fluorescence (TIRF) and STochastic Optical Reconstruction Microscopy (STORM);Zeiss 800 CLSM with Airyscan is an inverted microscope dramatically increasing conventional confocal image resolution to ~180 nm using Airyscan technology; Zeiss 710 LSM is inverted microscope supporting most basic imaging applications, multi channel and spectral, co localization, live cell, 3D, and time series imaging; Zeiss Celldiscoverer 7 is widefield imaging system for automated, time lapse imaging of live samples; Zeiss Axioscan 7 is high performance whole slide scanning system for fluorescence, brightfield, and polarization imaging;Miltenyi Biotec Ultramicroscope II Light Sheet fluorescence microscope (LSFM) extends fluorescent imaging into true 3D, large scale volumetric imaging of intact tissues, organs, and small organisms. AMCF also houses several high-end data analysis workstations with premier image analysis software including HALO (Indica Labs) and IMARIS (Oxford Instruments) facilitating data rendering, analyses, and presentation options.

Proper citation: University of Nebraska Medical Center Advanced Microscopy Core Facility (RRID:SCR_022467) Copy   

•   Source: SciCrunch Registry

http://www.ohri.ca/bioinformatics

Core of University of Ottawa and Ottawa Hospital Research Institute. Provides advice on bioinformatics research design, conduct bioinformatics analysis, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters and methodological text). Areas of expertise include:Analysis of high throughput sequencing data; single cell (Chromium 10x), RNA-seq (including small RNA), ChIP-seq, ATAC-seq, Hi-C.Large scale analysis integrating multiple data types.Helps to arrange for analysis of your biological samples with local core facilities such as StemCore, Proteomics Resource Center, or OHRI Mass Spectrometry Core Facility. Provides yearly training courses in RNA-seq analysis and Bioinformatics analysis using R as well as individual training and analysis support on request.

Proper citation: University of Ottawa Bioinformatics Core Facility (RRID:SCR_022466) Copy   

•   Source: SciCrunch Registry

https://cds.vanderbilt.edu

Shared Resource that offers bioinformatics and informatics services for basic research and clinical projects.

Proper citation: Vanderbilt University Creative Data Solutions Core Facility (RRID:SCR_022366) Copy   

•   Source: SciCrunch Registry

http://bioinf.itmat.upenn.edu/

Provides project based bioinformatics support for ITMAT translational researchers. Provides computational infrastructure and programming support needed to conduct high-throughput proteomics experiments. We also support other genomics high-throughput technologies to a lesser extent. The projects range from building Web applications for data analysis pipelines, scripting, clinical and basic science research support, and database and algorithm development. Recent efforts have focused on explorations of new models of computation, specifically cloud computing and GPUs, for use in genomic scale research.

Proper citation: University of Pennsylvania Perelman School of Medicine ITMAT Bioinformatics Laboratory Core Facility (RRID:SCR_022486) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CMSDLD/biomedical-data-science-core-bdsc.html

Core provides consultations and fee for service support in big data analyses using methods of data science in biomedical and health research related to digestive disease and liver research.

Proper citation: University of Pennsylvania Perelman School of Medicine Biomedical Data Science Core Facility (RRID:SCR_022485) Copy   

•   Source: SciCrunch Registry