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http://www.scienceexchange.com/facilities/mcgill-spr-facility

For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (_������������bait_������_) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner _������������target_������_) are then flowed overtop.

Proper citation: McGill SPR Facility (RRID:SCR_012265) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/psychiatry/research/pngu_home.aspx

Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.

Proper citation: MGH Psychiatric and Neurodevelopmental Genetics Unit Core Lab (RRID:SCR_012301) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-health-informatics-and-bioinformatics-nyu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 4th, 2023. Handles both low-level (instrument-specific, or upstream) informatics as well as higher-level (hypothesis testing and generation oriented, or downstream informatics). CHIBI also has the scientific responsibility for the high-end computing needed to process the genomic data.

Proper citation: New York University Center for Health Informatics and Bioinformatics (RRID:SCR_012300) Copy   

•   Source: SciCrunch Registry

https://www.usf.edu/arts-sciences/departments/chemistry/research/core-facilities/nmr.aspx

NMR facility provides state-of-the-art ultra-high field (14 and 18 Tesla) instruments that enable researchers to characterize protein structure at atomic resolution (along with the characterization of small molecules). Technical support and training are available for all aspects of project development. Experiments include structure elucidation of small molecules (e.g. synthetic molecules, natural products, and small peptides etc.) to studying advanced protein-ligand interactions.

Proper citation: USF NMR Laboratory (RRID:SCR_012260) Copy   

•   Source: SciCrunch Registry

https://viceprovost.tufts.edu/research-services/core-facilities-resources

Tufts University offers a wide range of facilities, tools, and services available to researchers at Tufts and beyond. A core facility is a facility that performs specific technical services, primarily for the internal research operations of the University and affiliated Medical Centers, and charges users for its services, or are free to investigators as they are paid for by another funding source.

Proper citation: Tufts University Core Facilities (RRID:SCR_012501) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/norc-diet-and-physical-activity-core/

Core that provides diet, physical activity, or statistical analysis consultation, as well as consultation for the design and development of diet and physical activity data collection protocols.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Diet and Physical Activity Core (RRID:SCR_012588) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genomics-and-proteomics-core-facility

The core facilities at DKFZ are undergoing a restructuring and consolidating phase to adopt the new requirements and to provide high quality, up-to-date service. The focus is upon steadily improving service offers and the establishment of novel technologies to enable investigators to address the scientific questions in cancer.

Proper citation: DKFZ Genomics and Proteomics Core Facility (RRID:SCR_012503) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bionet-academic-health-center-ahc

BioNet serves the University of Minnesota''''s Academic Health Center (AHC) as a centralized biorepository and bioregistry for patient consent and for the collection, processing, and distribution of de-identified tissue samples, blood and body fluids, purified DNA and specimen-matched clinical data for research. BioNet is becoming a major translational research resource linking clinical medicine, pathology, and basic and applied research to facilitate high quality and cost-conscious clinical and translational research. BioNet leverages the strengths of the Cancer Center''''s Tissue Procurement Facility (TPF), which has become part of BioNet. BioNet currently provides: * an optimized consenting process, * collection of tissue, blood, and fluid samples, * computerized specimen tracking systems that link -specimens to clinical data and other databases, * addition of core pathologist-supported facilities for histologic interpretation, immunohistochemistry, laser capture microdissection, and slide digitalization.

Proper citation: University of Minnesota Bionet - Academic Health Center (RRID:SCR_012469) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/monoclonal-antibody-core-facility-dfci-harvard

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2024. Monoclonal Antibody Core at Dana-Farber Cancer Institute produces novel monoclonal antibodies for use in basic research, drug discovery, and clinical applications including diagnosis, surrogate markers for disease status, response to therapy, and drug toxicity. Services include cloning and scale-up of immunization antigens to purification of the resulting antibodies. Researchers can choose to have all phases of antibody production conducted by the core or perform particular steps in their own lab. Services -Consultation on design of antigens and screening strategies -Production of vectors and protein with appropriate tags for immunization and screening -Immunization of animals including mice, rats and hamsters -Generation of monoclonal antibodies -Customized screening by WB, ELISA, flow cytometry -Antibody isotyping, titering, and specificity evaluation -Small, medium, and large-scale antibody production -Purification of antibodies -Antibody productivity assessment -Cryopreservation and recovery of hybridomas from liquid nitrogen -Hybridoma banking -Adaptation of hybridomas to serum-free media -Mycoplasma testing for hybridomas and other cell lines

Proper citation: DFCI Monoclonal Antibody Core Facility (RRID:SCR_012504) Copy   

•   Source: SciCrunch Registry

https://www.k-inbre.org/pages/k-inbre_about_bio-core.html

The K-INBRE Bioinformatics Core collaborates with Kansas researchers to perform research on cell and developmental biology. Core aims to serve the needs of investigators engaged in computationally intensive biomedical research, and to promote education in bioinformatics to students and researchers across the state of Kansas.

Proper citation: Kansas State University - INBRE Bioinformatics Core Facility (RRID:SCR_012596) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/epigenome-center-data-production-facility-usc

Core conducts genome-scale epigenetic and genetic data production and analysis, technology development, and epigenomic and population-based genomic research.

Proper citation: University of Southern California Epigenome Center Data Production Facility (RRID:SCR_012476) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/applied-genomics-technology-center-agtc-wayne-state

The Applied Genomics Technology Center (AGTC), a part of Wayne State University School of Medicine''''s Department of Obstetrics and Gynecology, is an exceptional research support core facility located on campus. Housed on the ground floor of the C.S. Mott Center for Human Growth and Development, the AGTC is a state-of-the-art, fee-for-service genomics center that provides a wide range of genomic technologies to the medical research community. In addition to instrumentation, AGTC personnel are available to work with investigators to optimize experiments to meet their scientific goals.

Proper citation: WSU Applied Genomics Technology Center (RRID:SCR_012519) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/plateforme-snp-transcriptome-and-epigenomics

THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 02, 2014. Core facility that plays an active role in the Loire Valley Region''s officially-accredited fields of competitive excellence: plant sciences, medicine and pharmacy, child-oriented research.

Proper citation: University of Angers Plateforme SNP Transcriptome and Epigenomics (RRID:SCR_012478) Copy   

•   Source: SciCrunch Registry

http://genepool.bio.ed.ac.uk/

The GenePool is a next-generation genomics and bioinformatics facility based within the School of Biological Sciences, The University of Edinburgh. Which offers collaborative access to DNA sequencing, genotyping and bioinformatics capabilities, using ABI 3730 Sanger, Illumina and Roche 454 technology platforms.

Proper citation: University of Edinburgh GenePool Next Generation Sequencing and Bioinformatics (RRID:SCR_012485) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/gene-targeting-and-transgenic-core-rochester

Currently, the Gene Targeting and Transgenic Core''s services include the production of mouse models using DNA microinjection and embryonic stem cell injection (from gene targeting in mouse ES cells to production of chimeric mice) methodologies. Additional services have included: various analytical techniques, embryo cryopreservation, rederivation of pathogen-free rodents, and assisted reproduction techniques (e.g., in vitro fertilization (IVF), superovulation, and embryo transfer). Specific strains, and alternative species and methods are considered when appropriate for individual research applications.

Proper citation: URMC Gene Targeting and Transgenic Core (RRID:SCR_012367) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-structure-core-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein Structure Core Facility operates in the department of Biochemistry and Molecular Biology, on the UNMC campus. The facility performs protein sequencing, amino acid analysis and peptide mapping on a fee-for-service basis. It is located on the first floor of the Durham Research Center

Proper citation: UNMC Protein Structure Core Facility (RRID:SCR_012609) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/babraham-commercialisation-services-ltd

Babraham Institute Enterprise Limited (BIE) is the wholly-owned trading arm of the Babraham Institute. The Babraham Institute undertakes innovative life-sciences research to discover the molecular mechanisms that underlie normal cellular processes and functions, with the aim of improving lifelong wellbeing and healthy ageing.

Proper citation: Babraham Institute Enterprise Limited (RRID:SCR_012566) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/clinical-pharmacology-analytical-services-cpas

The Clinical Pharmacology Analytical Services laboratory (CPAS) resides in the Department of Experimental and Clinical Pharmacology (ECP) in the University of Minnesota College of Pharmacy. CPAS offers quantification services of drug concentrations in biological samples. The CLIA-certified lab and its team of researchers and clinicians the resources to measure drug concentrations in blood and tissue samples of human and animal origin, including animals as patients and animals serving as research models. The lab which opened in October 2003 uses state-of-the-art equipment to facilitate analysis of drugs, xenobiotics, endogenous compounds and biological samples. Capabilities of the core lab include LC-MS/MS, LC-MS, GC-MS, HPLC-UV and HPLC-FLD. Additional, UV and fluorescent plate readers and liquid scintillation counters are available for conducting ELISA, RIA and other assays in a 96-well plate format. Because of its flexible structure, customers can purchase only the services they need, including assay consultation, assay development and validation, conduct of assays and application. Lab services are made available to researchers from within and outside the University of Minnesota community.

Proper citation: University of Minnesota Clinical Pharmacology Analytical Services (RRID:SCR_012603) Copy   

•   Source: SciCrunch Registry

https://www.montclair.edu/mmrl/

Interdisciplinary research, teaching and service facility equipped with scanning and transmission electron microscopes, an atomic force microscope, and the ancillary instruments. Provides microscopic imaging, X-ray analysis, and specimen preparation services for biological, pharmaceutical, and materials scientific research. The MMRL consist of four individual microscope rooms, the Histology laboratory, and sample preparation and chemical storage areas.Graduate- and upper-undergraduate-level training is offered in the operation of electron microscopes, sample preparation, and thick/thin sectioning. Currently, MMRL houses transmission electron, scanning electron microscopes, and atomic force microscope. The microscopes available for use include: - Hitachi H-7500 transmission electron microscope - Hitachi S-3400N variable pressure scanning electron microscope with x-ray analysis and digital imaging - Hitachi S-2460N scanning electron microscope with x-ray analysis In addition, the following items are also available for MMRL users: - Three Leica 2030 rotary paraffin microtome - Two LKB ultramicrotomes - A LKB 7800 glass knife maker - Leica Reichert Ultratrim - Denton critical point dryer - Denton sputter coaters (Desk II and Desk IV) - Denton Vacuum evaporators (DV-502A) - Liquid nitrogen dewars (various sizes) - A Leica stereo dissecting microscope - A Tissue-TeK VIP Tissue Processor - A Tissue-TeK II Embedding Center

Proper citation: Montclair University Microscopy and Microanalysis Research Laboratory Core Facility (RRID:SCR_012453) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/immunodetection-and-imaging

Delivering high quality immunohistochemical and immunofluorescent staining on cells and tissue sections, specialising in multi immunoflourescent colocalisation staining technologies. Equipped with three Vision Biosystems Bond staining robots Mike offers high throughput or custom antibody optimisation services. Time consuming multi colocalisation including same species primaries, are automated saving time and money. A large range of imaging platforms including three confocals, widefield, stereology, image analysis, digital photograpy and PALM laser capture microscopy are available. A full range of secondary antibodies and detection systems are available for purchase in ul quantities. There are currently 1900 antibodies recorded on our database.

Proper citation: University of Edinburgh Immunodetection and Imaging (RRID:SCR_012573) Copy   

•   Source: SciCrunch Registry