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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) software application, sequence analysis software, data processing software, software resource, data analysis software Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie
https://bio.tools/stringtie
https://sources.debian.org/src/stringtie/
SCR_016323 2026-02-15 09:21:38 4072
SVEngine
 
Resource Report
Resource Website
1+ mentions
SVEngine (RRID:SCR_016235) software application, sequence analysis software, data processing software, software resource, simulation software, data analysis software Software for analysis and simulation of gene sequences and structural variants. This software works with FASTA, FASTQ, BAM, VAR, META, and NEWICK file formats. structural, alteration, clonality, NGS, simulator, gene, allele, haplotype, variant NHGRI R01 HG006137;
CNSF 61370131
Free, Available to download SCR_016235 SVEngine: Allele Specific and Haplotype Aware Structural Variants Simulator 2026-02-15 09:21:34 3
RepeatModeler
 
Resource Report
Resource Website
1000+ mentions
RepeatModeler (RRID:SCR_015027) software application, sequence analysis software, data processing software, software resource, data analysis software Sequence analysis software that performs repeat family identification and creates models for sequence data. RepeatModeler utilizes RepeatScout and RECON to identify repeat element boundaries and family relationships., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence analysis, sequence repeats, repeat identification, bio.tools uses: RepeatScout
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Dfam
Institute for Systems Biology ;
NHGRI R44 HG02244;
NHGRI R01 HG002939
THIS RESOURCE IS NO LONGER IN SERVICE biotools:repeatmodeler https://bio.tools/repeatmodeler SCR_015027 2026-02-15 09:20:48 3193
BioDepot-workflow-builder
 
Resource Report
Resource Website
1+ mentions
BioDepot-workflow-builder (RRID:SCR_017402) Bwb workflow software, software application, data processing software, software resource Software tool to create and execute reproducible bioinformatics workflows using drag and drop interface. Graphical widgets represent Docker containers executing modular task. Widgets are linked graphically to build bioinformatics workflows that can be reproducibly deployed across different local and cloud platforms. Each widget contains form-based user interface to facilitate parameter entry and console to display intermediate results. bioinformatics, big, data, workflow, reproducible, Docker NIGMS R01 GM126019;
NHLBI U54 HL127624;
NHGRI U24HG012674;
NIAID R03AI159286
DOI:10.1016/j.cels.2019.08.007 Free, Available for download, Freely available SCR_017402 2026-02-15 09:22:02 1
Hapmix
 
Resource Report
Resource Website
10+ mentions
Hapmix (RRID:SCR_004203) HAPMIX software application, source code, software resource Software application that uses genotyping data from SNP arrays for accurately inferring chromosomal segments of distinct continental ancestry in admixed populations, using dense genetic data. (entry from Genetic Analysis Software) gene, genetic, genomic, admixed, population, genotype, single nucleotide polymorphism, ancestry, chromosomal segment, snp array is listed by: OMICtools
is listed by: Genetic Analysis Software
has parent organization: Harvard Medical School; Massachusetts; USA
NHGRI U01-HG004168;
NHLBI R01-HL087699
PMID:19543370 Restricted nlx_22768, OMICS_02082 http://www.hsph.harvard.edu/faculty/alkes-price/software/
http://www.stats.ox.ac.uk/~myers/software.html
https://reich.hms.harvard.edu/software
http://genetics.med.harvard.edu/reich/Reich_Lab/Software.html SCR_004203 2026-02-15 09:18:42 45
Human Experimental/FunctionAL MaPper: Providing Functional Maps of the Human Genome
 
Resource Report
Resource Website
Human Experimental/FunctionAL MaPper: Providing Functional Maps of the Human Genome (RRID:SCR_003506) HEFalMp data or information resource, database, service resource HEFalMp (Human Experimental/FunctionAL MaPper) is a tool developed by Curtis Huttenhower in Olga Troyanskaya's lab at Princeton University. It was created to allow interactive exploration of functional maps. Functional mapping analyzes portions of these networks related to user-specified groups of genes and biological processes and displays the results as probabilities (for individual genes), functional association p-values (for groups of genes), or graphically (as an interaction network). HEFalMp contains information from roughly 15,000 microarray conditions, over 15,000 publications on genetic and physical protein interactions, and several types of DNA and protein sequence analyses and allows the exploration of over 200 H. sapiens process-specific functional relationship networks, including a global, process-independent network capturing the most general functional relationships. Looking to download functional maps? Keep an eye on the bottom of each page of results: every functional map of any kind is generated with a Download link at the bottom right. Most functional maps are provided as tab-delimited text to simplify downstream processing; graphical interaction networks are provided as Support Vector Graphics files, which can be viewed using the Adobe Viewer, any recent version of Firefox, or the excellent open source Inkscape tool. human, map, gene, functional, pathway, disease, genomic, analysis, microarray, dna, protein, sequence has parent organization: Princeton University; New Jersey; USA New Jersey Commission on Cancer Research ;
PhRMA Foundation 2007RSGl9572;
NIGMS R01 GM071966;
NSF DBI-0546275;
NSF IIS-0513552;
NHGRI T32 HG003284;
NIGMS P50 GM071508
PMID:19246570 nif-0000-37186 SCR_003506 Human Experimental / FunctionAL MaPper, Human Experimental/FunctionAL MaPper 2026-02-15 09:18:31 0
FuncAssociate: The Gene Set Functionator
 
Resource Report
Resource Website
10+ mentions
FuncAssociate: The Gene Set Functionator (RRID:SCR_005768) FuncAssociate service resource, analysis service resource, data analysis service, production service resource A web-based tool that accepts as input a list of genes, and returns a list of GO attributes that are over- (or under-) represented among the genes in the input list. Only those over- (or under-) representations that are statistically significant, after correcting for multiple hypotheses testing, are reported. Currently 37 organisms are supported. In addition to the input list of genes, users may specify a) whether this list should be regarded as ordered or unordered; b) the universe of genes to be considered by FuncAssociate; c) whether to report over-, or under-represented attributes, or both; and d) the p-value cutoff. A new version of FuncAssociate supports a wider range of naming schemes for input genes, and uses more frequently updated GO associations. However, some features of the original version, such as sorting by LOD or the option to see the gene-attribute table, are not yet implemented. Platform: Online tool gene, gene ontology, statistical analysis, web service, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Roth Laboratory
NIH ;
Canadian Institute for Advanced Research ;
NINDS NS054052;
NINDS NS035611;
NHLBI HL081341;
NHGRI HG0017115;
NHGRI HG004233;
NHGRI HG003224
PMID:19717575
PMID:14668247
Free for academic use, Acknowledgement requested biotools:funcassociate, OMICS_02264, nlx_149233 http://llama.mshri.on.ca/cgi/func/funcassociate
https://bio.tools/funcassociate
SCR_005768 2026-02-15 09:19:03 36
ESEfinder 3.0
 
Resource Report
Resource Website
100+ mentions
ESEfinder 3.0 (RRID:SCR_007088) ESEfinder service resource, analysis service resource, data analysis service, production service resource A web-based resource that facilitates rapid analysis of exon sequences to identify putative exonic splicing enhancers (ESEs) responsive to the human SR proteins SF2/ASF, SC35, SRp40 and SRp55, and to predict whether exonic mutations disrupt such elements. exonic splicing enhancer, sr protein, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Cold Spring Harbor Laboratory
NIGMS GM42699;
NCI CA88351;
NHGRI HG01696
PMID:12824367 Free for non-profit use, Non-commercial, Acknowledgement requested, Commercial use with license biotools:esefinder, nif-0000-30496 http://rulai.cshl.edu/tools/ESE2/
https://bio.tools/esefinder
http://exon.cshl.edu/ESE/ SCR_007088 2026-02-15 09:19:27 211
CellProfiler Image Analysis Software
 
Resource Report
Resource Website
1000+ mentions
CellProfiler Image Analysis Software (RRID:SCR_007358) software application, image analysis software, data processing software, software resource Software tool to enable biologists without training in computer vision or programming to quantitatively measure phenotypes from thousands of images automatically. It counts cells and also measures the size, shape, intensity and texture of every cell (and every labeled subcellular compartment) in every image. It was designed for high throughput screening but can perform automated image analysis for images from time-lapse movies and low-throughput experiments. CellProfiler has an increasing number of algorithms to identify and measure properties of neuronal cell types. high-throughput, high content imaging, software, image, cell, phenotype, measurement, subcellular, intensity, size, shape, analysis, algorithm is listed by: Debian
is related to: CellProfiler Analyst
has parent organization: Broad Institute
NIGMS R01 GM089652;
NIGMS RC2 GM092519;
NHGRI RL1 HG004671
PMID:21349861
PMID:17076895
PMID:19014601
PMID:19188593
Free, Available for download, Freely available SCR_010649, nlx_66812, nif-0000-00280 https://sources.debian.org/src/cellprofiler/ SCR_007358 Cell Profiler, CellProfiler - cell image analysis software 2026-02-15 09:19:44 3265
GENCODE
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
GENCODE (RRID:SCR_014966) project portal, dataset, data or information resource, portal Human and mouse genome annotation project which aims to identify all gene features in the human genome using computational analysis, manual annotation, and experimental validation. human, mouse, genome, annotation, sequence, gene features, bio.tools is listed by: Debian
is listed by: bio.tools
is affiliated with: ENCODE
NHGRI 5U54HG004555;
Wellcome Trust WT098051
PMID:22955987 Free biotools:GENCODE https://bio.tools/GENCODE SCR_014966 ENCODE 2026-02-15 09:21:06 7700
Sniffles
 
Resource Report
Resource Website
50+ mentions
Sniffles (RRID:SCR_017619) software application, data processing software, software resource Software tool as structural variation caller using third generation sequencing (PacBio or Oxford Nanopore). It detects all types of SVs (10bp+) using evidence from split-read alignments, high-mismatch regions, and coverage analysis. Used to avoid single molecule long read sequencing high error rates. Structural, variation, caller, third, generation, sequencing, SV, split, read, alignment, mismatch, region, analysis, error, bio.tools is listed by: bio.tools
is listed by: Debian
NHGRI R01 HG006677;
NHGRI UM1 HG008898
PMID:29713083 Free, Available for download, Freely available biotools:sniffles https://bio.tools/sniffles SCR_017619 2026-02-15 09:22:05 59
liftOver
 
Resource Report
Resource Website
500+ mentions
liftOver (RRID:SCR_018160) software application, service resource, data processing software, software resource Web tool to convert genome coordinates and genome annotation files between assemblies. Used to translate genomic coordinates from one assembly version into another and retrieves putative orthologous regions in other species using UCSC chained and netted alignments. Convert genome coordinate, genome annotation file, translate genomic coordinate, assembly version, retrieve orthologous region is related to: UCSC Genome Browser
has parent organization: University of California at Santa Cruz; California; USA
NHGRI ;
Howard Hughes Medical Institute ;
NCI
DOI:10.1093/nar/gkj144 Free, Available for download, Freely available SCR_018160 2026-02-15 09:22:11 762
mosdepth
 
Resource Report
Resource Website
10+ mentions
mosdepth (RRID:SCR_018929) software application, data processing software, software resource Software command line tool for rapidly calculating genome wide sequencing coverage. Measures depth from BAM or CRAM files at either each nucleotide position in genome or for sets of genomic regions. Used for fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing quick coverage calculation for genomes and exomes. Calculating genome, wide sequencing coverage, depth measurement, BAM file, CRAM file, nucleotide position, genome, genomic region set, WGS exom, targeted sequencing, coverage calculation, exom, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG006693;
NHGRI R01 HG009141;
NIGMS R01 GM124355;
NCI U24 CA209999
PMID:29096012 Free, Available for download, Freely available OMICS_20873, biotools:mosdepth https://bio.tools/mosdepth
https://sources.debian.org/src/mosdepth/
SCR_018929 2026-02-15 09:22:17 38
ProteomeTools
 
Resource Report
Resource Website
10+ mentions
ProteomeTools (RRID:SCR_018535) project portal, data or information resource, portal Project for building molecular and digital tools from human proteome to facilitate biomedical research, drug discovery, personalized medicine and life science research. Molecular tool, human proteome, proteome, human, peptide, data is related to: ProteomicsDB
is related to: ProteomeXchange
German Federal Ministry of Education and Research ;
Alexander von Humboldt Foundation ;
American Recovery and Reinvestment Act ;
NHGRI RC2 HG005805;
NIGMS R01 GM087221;
NCRR S10 RR027584;
NIGMS P50 GM076547;
European Research Council ;
Swiss National Science Foundation
PMID:28135259 Free, Freely available http://www.proteometools.org SCR_018535 2026-02-15 09:22:22 21
DETONATE
 
Resource Report
Resource Website
1+ mentions
DETONATE (RRID:SCR_017035) DETONATE software application, sequence analysis software, data processing software, software resource, data analysis software Software tool to evaluate de novo transcriptome assemblies from RNA-Seq data. Consists of RSEM-EVAL and REF-EVAL packages. RSEM-EVAL is reference-free evaluation method. REF-EVAL is reference based and can be used to compare sets of any kinds of genomic sequences. evaluate, de novo, transcriptome, assembly, RNAseq, data, RSEM-EVAL, REF-EVAL, dataset, genomic, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
NHGRI R01 HG005232;
NLM T15 LM007359
PMID:25608678 Free, Available for download, Freely available biotools:detonate https://bio.tools/detonate SCR_017035 DE novo TranscriptOme rNa-seq Assembly with or without the Truth Evaluation, DETONATE 2026-02-15 09:21:57 2
miQC
 
Resource Report
Resource Website
1+ mentions
miQC (RRID:SCR_022697) software application, data processing software, data analysis software, software resource Software tool as flexible, probablistic metrics for quality control of scRNA-seq data. Adaptive probabilistic framework for quality control of single-cell RNA-sequencing data. Data driven QC metric that jointly models proportion of reads mapping to mtDNA and number of detected genes with mixture models in probabilistic framework to predict which cells are low quality in given dataset. scRNA-seq data quality control, QC metric, low quality data prediction, single cell RNA-sequencing data NCI CA237170;
NHGRI HG009007;
European Union Horizon 2020 research and innovation program ;
Academy of Finland ;
Cancer Foundation Finland
PMID:34428202 Free, Available for download, Freely available SCR_022697 2026-02-15 09:22:56 2
Reactome Knowledgebase
 
Resource Report
Resource Website
100+ mentions
Reactome Knowledgebase (RRID:SCR_023504) database, software resource, data access protocol, web service, data or information resource Open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. Core unit of Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form network of biological interactions and are grouped into pathways including classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. External domain expert provides expertise, curator formalizes it into database structure, and external domain expert reviews representation. System of evidence tracking ensures that all assertions are backed up by primary literature. Website is designed to give the user graphical map of known biological processes and pathways that is also an interface. Database and website enable to find, organize, and utilize biological information to support data visualization, integration and analysis. signaling and metabolic molecules relations, biological pathways and processes, intermediary metabolism, signaling, transcriptional regulation, apoptosis, disease NHGRI U24 HG012198 Free, Freely available SCR_023504 Reactome 2026-02-15 09:23:19 445
Michigan Imputation Server
 
Resource Report
Resource Website
1+ mentions
Michigan Imputation Server (RRID:SCR_023554) web service, data access protocol, software resource Web based service for imputation that facilitates access to new reference panels and improves user experience and productivity. Server implements whole genotype imputation workflow using MapReduce programming model for efficient parallelization of computationally intensive tasks. Genotype imputation service using Minimac4. Genotype imputation, whole genotype imputation workflow, parallelization of computationally intensive tasks, is related to: MINIMAC NHGRI HG007022;
NHLBI HL117626;
NHGRI HG000376;
NIDA R01DA037904;
Austrian Science Fund ;
European Community Seventh Framework Programme ;
NIA
PMID:27571263 Free, Freely available https://github.com/genepi/imputationserver SCR_023554 2026-02-15 09:23:12 8
Hetnet Connectivity Search
 
Resource Report
Resource Website
1+ mentions
Hetnet Connectivity Search (RRID:SCR_023630) Hetnet web service, data access protocol, software resource Web app that allows users to search for the most important paths connecting any two nodes in Hetionet. Hetionet, paths connection, paths search, paths connecting any two nodes in Hetionet, Pfizer Inc ;
NHGRI T32 HG000046;
NHGRI R01 HG010067;
NCI R01 CA237170;
Gordon and Betty Moore Foundation
PMID:36711546 Free, Freely available SCR_023630 , Heterogeneous network Connectivity Search, heterogeneous network 2026-02-15 09:23:13 1
CloVR
 
Resource Report
Resource Website
10+ mentions
CloVR (RRID:SCR_005290) CloVR service resource, software resource A desktop application for push-button automated sequence analysis that can utilize cloud computing resources. CloVR is implemented as a single portable virtual machine (VM) that provides several automated analysis pipelines for microbial genomics, including 16S, whole genome and metagenome sequence analysis. The CloVR VM runs on a personal computer, utilizes local computer resources and requires minimal installation, addressing key challenges in deploying bioinformatics workflows. In addition CloVR supports use of remote cloud computing resources to improve performance for large-scale sequence processing. cloud computing, next-generation sequencing is listed by: OMICtools
has parent organization: University of Maryland; Maryland; USA
Amazon Web Services in Education Research Grants program ;
National Human Genome Research Institute ;
NHGRI RC2 HG005597-01;
NSF 0949201
PMID:21878105 OMICS_01216 SCR_005290 CloVR - Automated Sequence Analysis from Your Desktop, Cloud Virtual Resource 2026-02-15 09:18:56 26

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