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http://www.scienceexchange.com/facilities/genomics-core

The mission of the Genomics Core is to provide state-of-the-art genomic services including genotyping and cell banking to investigators from UTHSCSA, CTRC and the local scientific community in an economical and timely manner.

Proper citation: UTHSCSA Genomics Core (RRID:SCR_012239) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-core-rochester

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Offers state-of-the-art Mass Spectrometry and Biomarker Separation and Analysis Services.

Proper citation: URMC Proteomics Core (RRID:SCR_012361) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/x-ray-crystallography-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15, 2024. The mission of the X-ray Crystallography Core Laboratory is to provide state-of-the-art resources to researchers at the University of Texas Health Science Center at San Antonio, and to external users, enabling the detailed 3-D analyses of biological macromolecules that play important roles in human health. This is a full service core in that it not only offers access to sophisticated equipment and technologies but also offers advice and technical assistance in sample preparation. Services are also provided to investigators without funding to facilitate the development of pilot data for new potentially fundable projects, as core resources permit. If priority of usage becomes an issue, this will be decided by the Core Director in consultation with the other principal scientists based on the feasibility of the projects, their scientific merits and their relevance to human health.

Proper citation: UTHSCSA X-ray Crystallography Core Laboratory (RRID:SCR_012242) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/microct-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22, 2024. UTHSCSA Orthopaedics Bone and Mineral High-Resolution 3D Imaging Facility is a NIH-funded imaging facility equipped with two ex-vivo desktop microCT systems, a reference point indenter and a furnace. The non-destructive nature of microCT imaging allows the researcher to strengthen his/her research by using the same sample for histology or biomechanical testing after microCT imaging. Advantages of Micro-CT - Micro-CT allows for extremely high-resolution, non-destructive, 3D imaging. - No staining, sectioning, or sample preparation needed - Samples can be frozen or fixed - Since Micro-CT is non-destructive, other assays may be carried out after, thereby increasing the amount of data per sample - Data acquisition is a rapid process, allowing for a speedy return of samples

Proper citation: UTHSCSA MicroCT Core Laboratory (RRID:SCR_012241) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/confocal-and-conventional-microscopy-core-rochester

The Confocal and Conventional Microscopy Core provides Medical Center researchers access to high-end confocal microscopy as well as more conventional brightfield and fluorescence microscopy. The Core provides assistance with all imaging procedures as needed by the investigators. Aid in customizing staining protocols to optimize obtainment of high quality data using Core instruments is also provided. The CCMC provides Medical Center researchers the ability and expertise to obtain high quality imaging-based data from tissue, culture, and materials-based research studies. Core instrumentation includes a new Olympus FV1000 laser scanning confocal microscope, an accompanying workstation containing full Olympus FV1000 software, an Olympus VanoxAH-2 microscope for brightfield and fluorescence imaging, and an imaging stand for large specimen imaging. The core also offers a PalmBeam Laser Capture Microdissection Instrument for microdissection of tissue.

Proper citation: URMC Confocal and Conventional Microscopy Core (RRID:SCR_012365) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/diygenomics

DIYgenomics provides crowdsourced health research study protocol design and operation in pre-clinical and disease cohorts. Founded in 2010, the mission of DIYgenomics is the realization of preventive medicine through the integrated study of multiple health data streams. The generalized hypothesis for DIYgenomics studies is that one or more genetic polymorphisms (mutations) may result in out-of-bounds phenotypic biomarker conditions (for example, low Vitamin B blood levels), that may be ameliorated through personalized intervention.

Proper citation: DIYgenomics (RRID:SCR_012243) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/marvell-nanofabrication-laboratory, micro/nanoelectromechanical systems, microelectronics

The Marvell Nanofabrication Laboratory at the University of California, Berkeley is a multidisciplinary facility that serves research and education in the areas of integrated circuits (ICs) and systems, micro/nanofabrication technologies, micro/nanoelectromechanical (MEMS/NEMS) systems, advanced materials and interdisciplinary applications of microelectronics. This facility offers processing for both 4 inch and 6 inch substrates (wafers).

Proper citation: UC Berkeley Marvell Nanofabrication Laboratory (RRID:SCR_012246) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/gene-targeting-and-transgenic-core-rochester

Currently, the Gene Targeting and Transgenic Core''s services include the production of mouse models using DNA microinjection and embryonic stem cell injection (from gene targeting in mouse ES cells to production of chimeric mice) methodologies. Additional services have included: various analytical techniques, embryo cryopreservation, rederivation of pathogen-free rodents, and assisted reproduction techniques (e.g., in vitro fertilization (IVF), superovulation, and embryo transfer). Specific strains, and alternative species and methods are considered when appropriate for individual research applications.

Proper citation: URMC Gene Targeting and Transgenic Core (RRID:SCR_012367) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/metabolomics-core-laboratory-mass-spectrometry-uthscsa

Cutting-edge mass spectrometers deliver extremely high mass accuracy and resolution to elucidate the identity and quantity of small molecules. Metabolomics Laboratory Services: Qualitative and quantitative analysis of small molecules - Molecular mass determination - Structural elucidation - Quantification Targeted and discovery modes of analysis - Quantitative analysis of targeted metabolites - Metabolite profiling for differential comparisons between experimental groups - High-throughput sample analysis The Metabolomics Laboratory is supported by awards from the National Institutes of Health, including a Shared Instrumentation grant (1S10RR031586-01) and a supplement to the Clinical and Translational Sciences Award (3UL1RR025767-03S1).

Proper citation: UTHSCSA Metabolomics Core Laboratory Mass Spectrometry (RRID:SCR_012245) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cell-imaging-centre

The Cell Imaging Centre is primarily equipped to benefit research scientists within the faculty of medicine and dentistry at the University of Alberta, and is also available to accommodate users from other academic institutes and commercial companies.

Proper citation: UAlberta Cell Imaging Centre (RRID:SCR_012325) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/martinos-center-for-biomedical-imaging-core-facility-harvard

Core facility that provides the following services: Positron emission tomography service.

The Martinos Center''''s dual mission includes translational research and technology development. The core technologies being developed and used at the center are magnetic resonance imaging (MRI) and spectroscopy (MRS), magnetoencephalography (MEG) and electroencephalograpy (EEG), near infra-red spectroscopy (NIRS) and diffuse optical tomography (DOT), Positron Emission Tomography (PET), electrophysiology, molecular imaging, and computational image analysis. A particular area of innovation at the Center is Multimodal Functional Neuroimaging which involves the integration of imaging technologies. They are also world leaders in the development of primate neuroimaging techniques. Major areas of research at the center include, psychiatric, neurologic and neurovascular disorders, basic and cognitive neuroscience, cardiovascular disease, cancer and more. With an extensive and expanding inventory of state-of-the-art imaging facilities, a world class team of investigators and collaborators, and important government, industry and private supporters, the Martinos Center is leading the way to new advances and applications in biomedical imaging.

Proper citation: MGH Martinos Center for Biomedical Imaging Core Facility (RRID:SCR_012324) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bioinformatics-support-unit

Core provides support to life science researchers with data analysis and experimental design from sequence analysis, microarrays, proteomics and beyond.

Proper citation: Newcastle University Bioinformatics Support Unit (RRID:SCR_012297) Copy   

•   Source: SciCrunch Registry

https://www.joslin.org/islet-isolation-core.html

Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.

Proper citation: Joslin Diabetes Center Islet Isolation Core (RRID:SCR_012299) Copy   

•   Source: SciCrunch Registry

https://www.dfhcc.harvard.edu/research/core-facilities/tumor-imaging-metrics

Core provides centralized, standardized, accurate, consistent, and timely longitudinal, multimodality anatomic, volumetric and functional tumor metrics including CT, MR, PET/CT and other nuclear medicine imaging studies to evaluate therapeutic response for patients enrolled in DF/HCC oncologic clinical trials. TIMC supports more than 30 tumor response assessment criteria including but not limited to RECIST 1.1, iRECIST, Lugano, LYRIC, IWCLL and RANO. Results of tumor metric analyses are offered on password-protected secure web-based report.

Proper citation: Harvard Tumor Imaging Metrics Core Facility (RRID:SCR_012298) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/igsp-genome-sequencing-analysis-core-duke

The mission of the Genome Sequencing & Analysis Core Resource is to promote advance in biology by providing to researchers complete genomic solutions with the latest and most complementary technologies readily available. We provide services for traditional capillary sequencing, high-throughput next-generation sequencing, and various data analyses, both across Duke University campus and across the world. We offer services on seven sequencers at the moment.

Proper citation: Duke IGSP Genome Sequencing and Analysis Core (RRID:SCR_012331) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/host-microbe-systems-biology-core-uc-davis

The UC Davis Host-Microbe Systems Biology Core offers NGS analytical services which will utilize state-of-the-art open source software platforms and other customized scripts developed by the HMSB Core co-Director Jonathan Eisen, Ph.D. The HMSB Core is designed to provide researchers with easily accessible, customized, and cost-effective resources for integrating analyses of microbial community structure and host-microbe interactions in health and disease.

Proper citation: UC Davis Host-Microbe Systems Biology Core (RRID:SCR_012334) Copy   

•   Source: SciCrunch Registry

https://moffitt.org/research-science/shared-resources/molecular-genomics/

Molecular Genomics Core Facility at Moffitt Cancer Center in Tampa, FL offers services to assess gene expression, epigenetic modification and sequence variation. Performs bulk and single cell RNA and DNA sequencing on Illumina platform, NanoString nCounter, GeneChip and Illumina array services.Offers services to discuss your project and timeline for your project.

Proper citation: Moffitt Cancer Center Molecular Genomics Core Facility (RRID:SCR_012333) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/fluorescence-microscopy-and-imaging-core-laboratory

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 22, 2024. The Fluorescence Microscopy and Imaging Core Laboratory is a multi-user facility located in the Department of Pathology and Laboratory Medicine at The University of Texas Medical School Houston, within the Texas Medical Center. Its purpose is to allow research scientists access to state of the art Fluorescence Microscopes and Imaging equipment, to foster experimentation for the further understanding of scientific phenomena in many diverse areas of clinical and basic research.

Proper citation: UTHealth Fluorescence Microscopy and Imaging Core Laboratory (RRID:SCR_012293) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/ucla-nanoelectronics-research-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Core facility

Proper citation: UCLA Nanoelectronics Research Facility (RRID:SCR_012337) Copy   

•   Source: SciCrunch Registry

https://core.uconn.edu/resources/flowcytometry

Provides investigators with access to sophisticated instruments designed to detect and measure fluorescent light emission. Flow cytometers distinguish cells or particles based on size, internal complexity, and fluorescent signals. Cells or particles can also be sorted to obtain pure populations for further analysis or subsequent culture. Available imaging techniques include widefield, laser scanning confocal, spinning disk confocal, TIRF, and multiphoton confocal microscopy.

Proper citation: Connecticut University Flow Cytometry Core Facility (RRID:SCR_012341) Copy   

•   Source: SciCrunch Registry