SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.scienceexchange.com/facilities/microarray-and-bioinformatics-core-mmc
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Core facility that provides the following services: RNA quality analysis service, qRT-PCR service, Microarray service, Bioinformatics data analysis service. The Core provides state of the art training, instrumentation, services and bioinformatics-driven data analysis to the Meharry Community in microarray experimental design, manipulation, and gene expression analysis. They also aid investigators and trainees in validation of microarray results using RNA QA/QC and real time PCR results. Finally, this Core Resource aids Meharry investigators and trainees with high performance computation in proteomics as well as genomics. Gene and protein pathways analysis and shotgun proteomics (mass spectrometry) analysis are just two more of the services that we provide. It is their aim to keep this facility up to date computationally and intellectually with state of the art Omics services to support education and research in microarray, genomics and proteomics data analysis, computational biology, and systems biology.
Proper citation: Meharry Microarray and Bioinformatics Core (RRID:SCR_012229) Copy
Core facility that provides the following services: Positron emission tomography service.
The Martinos Center''''s dual mission includes translational research and technology development. The core technologies being developed and used at the center are magnetic resonance imaging (MRI) and spectroscopy (MRS), magnetoencephalography (MEG) and electroencephalograpy (EEG), near infra-red spectroscopy (NIRS) and diffuse optical tomography (DOT), Positron Emission Tomography (PET), electrophysiology, molecular imaging, and computational image analysis. A particular area of innovation at the Center is Multimodal Functional Neuroimaging which involves the integration of imaging technologies. They are also world leaders in the development of primate neuroimaging techniques. Major areas of research at the center include, psychiatric, neurologic and neurovascular disorders, basic and cognitive neuroscience, cardiovascular disease, cancer and more. With an extensive and expanding inventory of state-of-the-art imaging facilities, a world class team of investigators and collaborators, and important government, industry and private supporters, the Martinos Center is leading the way to new advances and applications in biomedical imaging.
Proper citation: MGH Martinos Center for Biomedical Imaging Core Facility (RRID:SCR_012324) Copy
https://www.joslin.org/islet-isolation-core.html
Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.
Proper citation: Joslin Diabetes Center Islet Isolation Core (RRID:SCR_012299) Copy
http://www.schepens.harvard.edu/graphics
Core facility that provides the following services: Web and graphic services, Web design and content management service, Photography service. Peter Mallen is a designer and illustrator who manages a full-service web and graphics studio in a moderately sized scientific research facility, Schepens Eye Research Institute. He provides a full range of graphic design, scientific illustration, web design and development, content management, and general design and production services. His products are utilized by: faculty and scientific staff (books, scientific publications, slide shows, grant applications); professional staff (Administration, Development & Public Affairs; brochures, books, pamphlets); the general public (Institute websites) as well as clients of our 250-seat state-of-the-art conference center, Starr Center for Scientific Communications.
Proper citation: Harvard SERI Graphic Services Core (RRID:SCR_012309) Copy
http://www.massgeneral.org/psychiatry/research/pngu_home.aspx
Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.
Proper citation: MGH Psychiatric and Neurodevelopmental Genetics Unit Core Lab (RRID:SCR_012301) Copy
http://www.hunter.cuny.edu/chemistry/facilities/nmr/home
A service facility with four main spectrometers. The facility consists of four NMR instruments: a JEOL GX-400, a Varian Inova 500, a Bruker Avance 500 equipped with a 13C-1H cryoprobe, and a Bruker Avance III 600 MHz spectrometer equipped with a cryoprobe. These spectrometers are utilized by scientists from Hunter College, as well as from the entire CUNY community. The large variety of available probes allows detection of virtually any MR-active nuclide. Data analysis is performed either at the spectrometer workstation with vendor software or off-line with third party software packages.
Proper citation: Hunter NMR Spectroscopy Facility (RRID:SCR_000883) Copy
http://famu.eagle-i.net/i/00000136-ea13-62c9-2e84-177780000000
A core facility at the Florida Agricultural and Mechanical University.
Proper citation: FAMU Drug Discovery Core Facility (RRID:SCR_000876) Copy
http://harvard.eagle-i.net/i/0000012c-c7e5-e09d-a061-4a6580000000
Core facility that provides the following services: Flow cytometry assay service, Data management system.
The BD FACSCalibur system combines unique dual-laser technology, an automated sample loader option, and powerful software to provide the high throughput necessary to meet productivity requirements of clinical laboratories. The modularity and innovative technology designed into the BD FACSCalibur system also offers investigators the performance and flexibility required for a variety of research applications. Please note that since the NERCE program will end in February 2014, our ability to support new requests for services is limited.
Proper citation: HMS NERCE FACSCalibur Flow Cytometer Resource (RRID:SCR_000879) Copy
http://famu.eagle-i.net/i/00000137-5195-0786-f0f1-ede280000000
A laboratory equipped with laser-based flow cytometric instruments, the main one being the Becton Dickinson two-laser FACScalibur analyzer. This facility provides a resource for analytical and preparative studies of cells using flow cytometry to the FAMU biomedical researchers. This facility offers FACS acquisition and analysis for detecting cell surface or intracellular proteins, measuring apoptosis, cell cycle, cellular physiology that have both biomedical and clinical applications.
Proper citation: FAMU Flow cytometry laboratory (RRID:SCR_000877) Copy
http://harvard.eagle-i.net/i/0000012c-7441-2a90-c437-ff0b80000000
Core facility that provides the following services: Tissue trimming, cassetting, processing, and embedding, Cutting and staining of paraffin-embedded and cryostat sections, Immunohistochemistry for both routine and novel markers, In situ hybridization, using chromogenic or radioactive detection methods, Laser capture microdissection.
Tissue analysis is critical to validation and evaluation of animal models of human cancer, and human cancer tissues serve as the operating system for translational research. The facility supports a wide spectrum of cancer-relevant research, from basic studies on pathogenic mechanisms in cancer to translational research focused on the development of new tests for biomarkers that stratify patients and direct therapy. The Specialized Histopathology (SHP) Core, was created in 2005 by consolidating five histopathology cores into a single unit with two performance sites: Longwood, Directed by Jon Aster and based at the Brigham and Women?s Hospital and MGH, Directed by Anat Stemmer-Rachamimov and based at Massachusetts General Hospital East in Charlestown. The SHP Core provides professional and technical research pathology services to DF/HCC investigators working in diverse organisms (e.g., rodents, fish, and monkeys) or human tissues. The Core also assists in experimental design and the development and interpretation of tests and their results. As of July 2012, the Longwood site offers CLIA Certified services.
Proper citation: DF/HCC Specialized Histopathology Services Core (RRID:SCR_000872) Copy
http://wyss.harvard.edu/viewpage/594/
A core facility with access to imaging equipment and analysis software such as wide-field light microscopy, Total Internal Reflection Fluorescence microscopy (TIRF), confocal microscopy, Atomic Force Microscopy (AFM), Transmission Electron Microscopy (TEM), small animal imaging, spectroscopy, and flow cytometry.
Proper citation: Wyss Institute Imaging Core (RRID:SCR_000898) Copy
http://eagle-i.itmat.upenn.edu/i/0000013c-40b7-7a2a-f162-a2b280000000
Core facility that provides the following services: PET/SPECT/CT image analysis.
Proper citation: Penn Small Animal Imaging Facility: PET/SPECT/CT Sub-Core (RRID:SCR_000890) Copy
http://jsu.eagle-i.net/i/0000012b-00bd-5152-3984-bcfb80000000
A research laboratory and facility which supports research on environmental toxicology at Jackson State University.
Proper citation: JSU Environmental Toxicology Core Lab (RRID:SCR_000884) Copy
http://www.cma.mgh.harvard.edu/
A center dedicated to developing and applying morphometric methods to biomedical imaging data such as high-resolution MRI. The lab uses automated and semi-automated software such that MRI brain images are segmented into anatomical regions of interest. Projects in both basic and applied brain research include research on strokes and tumors; medical image processing research includes shape analysis of anatomical brain regions and measurement and analysis of brain volumes.
Proper citation: MGH Center for Morphometric Analysis (RRID:SCR_000885) Copy
http://harvard.eagle-i.net/i/0000012e-3517-ac53-550e-f59280000000
Core facility that provides metals analytical capabilities to biomedical and non-biomedical researchers and serves as a source for study design consultation and sample QA/QC requirements. The transport, fate, exposure, and toxic effects of heavy metals is a primary focus of research at the Center. It operates as a modified fee-for-service laboratory. Researchers have the option of having the samples run by the Service staff, or of receiving instruction (for themselves or a doctoral or post doctoral trainee) on how to operate the analytical equipment and analyze their own samples. Both options have associated fees and, as with other services, facility access funds can be requested internal or external services when individual grant support is not yet available.
Proper citation: HSPH Trace Metals Laboratory (RRID:SCR_002819) Copy
http://biology.hunter.cuny.edu/index.php?option=com_content&view=article&id=138&Itemid=117
Facility which provides instruments and instrument resources for analyzing DNA, RNA, protein, and radio-labeled substances.
Proper citation: Hunter Genomic Facility (RRID:SCR_001983) Copy
http://upr.eagle-i.net/i/0000012a-250e-1301-43fb-601a80000000
THIS RESOURCE IS NO LONGER IN SERVICE, documented June 26, 2017. Lab that provides resources for researchers such as image analysis and access to confocal microscopes.
Proper citation: UPR Analysis Resource Center Confocal Microscopy Core Laboratory (RRID:SCR_002330) Copy
http://harvard.eagle-i.net/i/0000013c-fd63-dfbb-ea7a-a3a980000000
Core facility that provides the following services: Circulating Tumor Cell analysis, Circulating Tumor Cell Purification. The Circulating Tumor Cell Core Facility uses immunomagnetic technology developed by Veridex, LLC (Raritan, NJ) to isolate rare tumor cells from whole blood. Isolated tumor cells can then be counted or used for downstream analysis such as molecular studies or flow cytometry.
Proper citation: BWH Circulating Tumor Cell Core (RRID:SCR_008258) Copy
http://harvard.eagle-i.net/i/00000137-e19e-59a0-d807-77a880000000
Microscopists at Weld Hill will find a range of tools from the simple hand lens to the confocal microscope for 3-D reconstructions.
Proper citation: Arnold Arboretum of Harvard University: Weld Hill Microscopy Lab (RRID:SCR_004485) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-c61a-a13e-b341-4bb480000000
Core facility that provides the following services: Energy Expenditure Assessment, Body Composition Assessment, Physical Activity Assessment. This component of the core utilizes existing institutional resources for measurement of energy balance and provides personnel support that permit assessment of research in energy balance and nutrition assessment.
Proper citation: Vanderbilt Energy Balance Core Laboratory (RRID:SCR_006665) Copy
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