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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://www.jax.org/strain/022760
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: nitric oxide synthase 3; endothelial cell|Fas cell surface death receptor
Genomic Alteration: targeted mutation 1; University of North Carolina|lymphoproliferation
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: nitric oxide synthase 3; endothelial cell|Fas cell surface death receptor; mutant strain|congenic strain: Nos3|Fas
Proper citation: RRID:IMSR_JAX:022760 Copy
Issue Issue
https://www.jax.org/strain/024314
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor receptor superfamily; member 1a
Genomic Alteration: targeted mutation 1; Immunex Research and Development Corporation
Availability: sperm
References:
Synonyms: NOD.TNFR1KO/TNFR2KO
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 1b|tumor necrosis factor receptor superfamily; member 1a; mutant strain|congenic strain: Tnfrsf1b|Tnfrsf1a
Proper citation: RRID:IMSR_JAX:024314 Copy
Issue
https://www.jax.org/strain/024476
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: signal transducer and activator of transcription 4|T cell receptor alpha chain|transgene insertion 1; Christophe Benoist|T cell receptor beta chain|thymus cell antigen 1; theta|interferon gamma receptor 1
Genomic Alteration: targeted mutation 1; Michael J Grusby|transgene insertion 1; Christophe Benoist|a variant|targeted mutation 1; Michel Aguet
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: signal transducer and activator of transcription 4|T cell receptor alpha chain|transgene insertion 1; Christophe Benoist|T cell receptor beta chain|thymus cell antigen 1; theta|interferon gamma receptor 1; mutant strain|congenic strain: Stat4|Tcra|Tg(TcraBDC2.5;TcrbBDC2.5)1Doi|Tcrb|Thy1|Ifngr1
Proper citation: RRID:IMSR_JAX:024476 Copy
Issue Issue
https://www.jax.org/strain/018122
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: prion protein
Genomic Alteration: targeted mutation 1; Charles Weissmann
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: prion protein; mutant strain|congenic strain: Prnp
Proper citation: RRID:IMSR_JAX:018122 Copy
Issue
https://www.jax.org/strain/019103
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: nestin|transgene insertion 1; Rudiger Klein|
Genomic Alteration: transgene insertion 1; Rudiger Klein
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: nestin|transgene insertion 1; Rudiger Klein|; mutant strain|congenic strain: Nes|Tg(Nes-cre)1Kln|
Proper citation: RRID:IMSR_JAX:019103 Copy
Issue
https://www.jax.org/strain/018972
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: myosin; heavy polypeptide 6; cardiac muscle; alpha|transgene insertion 2182; Michael D Schneider|
Genomic Alteration: transgene insertion 2182; Michael D Schneider
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: myosin; heavy polypeptide 6; cardiac muscle; alpha|transgene insertion 2182; Michael D Schneider|; mutant strain|congenic strain: Myh6|Tg(Myh6-cre)2182Mds|
Proper citation: RRID:IMSR_JAX:018972 Copy
Issue
https://www.jax.org/strain/032435
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: Kras proto-oncogene; GTPase|transformation related protein 53
Genomic Alteration: targeted mutation 4; Tyler Jacks|targeted mutation 1; Anton Berns
Availability: live
References:
Synonyms:
Notes: gene symbol note: Kras proto-oncogene; GTPase|transformation related protein 53; mutant strain|congenic strain: Kras|Trp53
Proper citation: RRID:IMSR_JAX:032435 Copy
Issue
https://www.jax.org/strain/033964
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: pancreas specific transcription factor; 1a|phosphatase and tensin homolog|Kras proto-oncogene; GTPase|Cre recombinase and estrogen receptor 1 fusion gene
Genomic Alteration: targeted mutation 2; Christopher VE Wright|targeted mutation 1; Hong Wu|targeted mutation 4; Tyler Jacks
Availability: live
References:
Synonyms: KPP
Notes: gene symbol note: pancreas specific transcription factor; 1a|phosphatase and tensin homolog|Kras proto-oncogene; GTPase|Cre recombinase and estrogen receptor 1 fusion gene; mutant strain|congenic strain: Ptf1a|Pten|Kras|cre/Esr1
Proper citation: RRID:IMSR_JAX:033964 Copy
Issue
https://www.jax.org/strain/007224
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: DNA segment; Chr 12; Massachusetts Institute of Technology 2|DNA segment; Chr 12; Massachusetts Institute of Technology 182|atherosclerosis 6|apolipoprotein E
Genomic Alteration: |C57BLKS/J|targeted mutation 1; University of North Carolina
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: DNA segment; Chr 12; Massachusetts Institute of Technology 2|DNA segment; Chr 12; Massachusetts Institute of Technology 182|atherosclerosis 6|apolipoprotein E; mutant strain|congenic strain: D12Mit2|D12Mit182|Ath6|Apoe
Proper citation: RRID:IMSR_JAX:007224 Copy
Issue
https://www.jax.org/strain/008179
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 4; Tyler Jacks
Availability: live
References:
Synonyms:
Notes: gene symbol note: Kras proto-oncogene; GTPase; congenic strain: Kras
Proper citation: RRID:IMSR_JAX:008179 Copy
Issue
https://www.jax.org/strain/008228
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: interferon gamma
Genomic Alteration: targeted mutation 1; Timothy Stewart
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: interferon gamma; mutant strain|congenic strain: Ifng
Proper citation: RRID:IMSR_JAX:008228 Copy
Issue
https://www.jax.org/strain/008471
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: oxytocin receptor
Genomic Alteration: targeted mutation 1.1; W Scott Young III
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: oxytocin receptor; congenic strain: Oxtr
Proper citation: RRID:IMSR_JAX:008471 Copy
Issue Issue
https://www.jax.org/strain/009085
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: ret proto-oncogene
Genomic Alteration: targeted mutation 1; Frank Costantini
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: ret proto-oncogene; mutant strain: Ret
Proper citation: RRID:IMSR_JAX:009085 Copy
Issue
https://www.jax.org/strain/002052
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: apolipoprotein E
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: live
References:
Synonyms:
Notes: gene symbol note: apolipoprotein E; mutant strain|congenic strain: Apoe
Proper citation: RRID:IMSR_JAX:002052 Copy
Issue
https://www.jax.org/strain/002070
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: beta-2 microglobulin; mutant stock: B2m
Proper citation: RRID:IMSR_JAX:002070 Copy
Issue
https://www.jax.org/strain/002245
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: apolipoprotein E|low density lipoprotein receptor
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Joachim Herz
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: apolipoprotein E|low density lipoprotein receptor; mutant stock: Apoe|Ldlr
Proper citation: RRID:IMSR_JAX:002245 Copy
Issue
https://www.jax.org/strain/002246
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: apolipoprotein E|low density lipoprotein receptor
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Joachim Herz
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: apolipoprotein E|low density lipoprotein receptor; mutant strain|congenic strain: Apoe|Ldlr
Proper citation: RRID:IMSR_JAX:002246 Copy
Issue Issue
https://www.jax.org/strain/002254
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: sperm
References:
Synonyms: B6;129S6-Il6
Notes: gene symbol note: interleukin 6; mutant stock: Il6
Proper citation: RRID:IMSR_JAX:002254 Copy
Issue
https://www.jax.org/strain/002268
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: CD4 antigen
Genomic Alteration: targeted mutation 1; Barbara B Knowles
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: CD4 antigen; mutant stock: Cd4
Proper citation: RRID:IMSR_JAX:002268 Copy
Issue
https://www.jax.org/strain/002269
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: CD4 antigen
Genomic Alteration: targeted mutation 1; Barbara B Knowles
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: CD4 antigen; mutant strain|congenic strain: Cd4
Proper citation: RRID:IMSR_JAX:002269 Copy
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