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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Genetic Background:
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
References:
Synonyms: TLR2 KO. B6.129P2-Tlr2
Notes: gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2
Proper citation: RRID:IMSR_OBS:3 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-model.htm
Source Database: genOway
Genetic Background:
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|unknown|targeted mutation 1; University of Cologne
Availability: live
References:
Synonyms: C.Cg-Rag2
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain; coisogenic strain|mutant strain: Rag2|Flt3|Sirpa|Il2rg
Proper citation: RRID:IMSR_BRGSF Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Genetic Background:
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
References:
Synonyms: C.129P2(B6)-Tlr2
Notes: gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2
Proper citation: RRID:IMSR_OBS:9 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-a2-his.htm
Source Database: genOway
Genetic Background:
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|targeted mutation 1; University of Cologne|unknown|transgene insertion 1; Beatrice Perarnau
Availability: live
References:
Synonyms: C.Cg-Rag2
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin; coisogenic strain|mutant strain: Rag2|Flt3|Il2rg|Sirpa|H2-D|HLA-A2.1|B2m
Proper citation: RRID:IMSR_BRGSF-A2 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=37
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
References:
Synonyms: C57BL/6 - lpr. B6-Tnfrsf6
Notes: gene symbol note: Fas cell surface death receptor; congenic strain: Fas
Proper citation: RRID:IMSR_EM:00037 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=30
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Christophe Benoist and Diane Mathis|targeted mutation 1; University of North Carolina
Availability: embryo
References:
Synonyms: B6.Cg-B2m
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin; mutant strain: H2-Ab1|B2m
Proper citation: RRID:IMSR_EM:00030 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=64
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: transgene insertion e19h; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion e19h; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
References:
Synonyms: PrPC-KO. E1931. B6;129S7-Prnp
Notes: gene symbol note: transgene insertion e19h; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)e19hCwe|Prnp
Proper citation: RRID:IMSR_EM:00064 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=56
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: transgene insertion d11; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion d11; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
References:
Synonyms: STOCK Prnp
Notes: gene symbol note: transgene insertion d11; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)d11Cwe|Prnp
Proper citation: RRID:IMSR_EM:00056 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=177
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: prion protein|transgene insertion 19; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion 19; Charles Weissmann
Availability: embryo
References:
Synonyms: B6;129S7 Prnp
Notes: gene symbol note: prion protein|transgene insertion 19; Charles Weissmann; mutant strain: Prnp|Tg(Alb1-Prnp)19Cwe
Proper citation: RRID:IMSR_EM:00177 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=179
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: transgene insertion 71; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion 71; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
References:
Synonyms: STOCK Prnp
Notes: gene symbol note: transgene insertion 71; Charles Weissmann|prion protein; mutant strain: Tg(Lck-Prnp)71Cwe|Prnp
Proper citation: RRID:IMSR_EM:00179 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=176
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: prion protein|transgene insertion 01; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion 01; Charles Weissmann
Availability: embryo
References:
Synonyms: STOCK Prnp
Notes: gene symbol note: prion protein|transgene insertion 01; Charles Weissmann; mutant strain: Prnp|Tg(Alb1-Prnp)01Cwe
Proper citation: RRID:IMSR_EM:00176 Copy
Issue Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=394
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: immunoglobulin heavy constant mu|apolipoprotein E
Genomic Alteration: targeted mutation 1; University of Cologne|targeted mutation 1; University of North Carolina
Availability: embryo
References:
Synonyms: apolipoprotein E KO and muMT KO. B6.129(Cg)-Apoe
Notes: gene symbol note: immunoglobulin heavy constant mu|apolipoprotein E; mutant strain: Ighm|Apoe
Proper citation: RRID:IMSR_EM:00394 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=395
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: T cell receptor delta chain|apolipoprotein E
Genomic Alteration: targeted mutation 1; Peter Mombaerts|targeted mutation 1; University of North Carolina
Availability: embryo
References:
Synonyms: apolipoprotein E KO and TCRdeltaKO
Notes: gene symbol note: T cell receptor delta chain|apolipoprotein E; mutant strain: Tcrd|Apoe
Proper citation: RRID:IMSR_EM:00395 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=213
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Christophe Benoist and Diane Mathis
Availability: embryo
References:
Synonyms: NOD.129(B6)-B2m
Notes: gene symbol note: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1; mutant strain: B2m|H2-Ab1
Proper citation: RRID:IMSR_EM:00213 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1218
Source Database: European Mouse Mutant Archive
Genetic Background:
Affected Genes: insulin II
Genomic Alteration: targeted mutation 1; Jacques Jami
Availability: embryo
References:
Synonyms: Ins/2_LacZ_129
Notes: gene symbol note: insulin II; mutant strain: Ins2
Proper citation: RRID:IMSR_EM:01218 Copy
Issue Issue
https://www.envigo.com/model/b6-129-rag2tm1fwaii2rgtm1rsky-dwlhsd
Source Database: Envigo an Inotiv Company
Genetic Background:
Affected Genes: recombination activating gene 2|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; University of Cologne
Availability: live
References:
Synonyms: B6;129-Rag2
Notes: gene symbol note: recombination activating gene 2|interleukin 2 receptor; gamma chain; mutant strain|inbred strain: Rag2|Il2rg
Proper citation: RRID:IMSR_ENV:HSD-021 Copy
Issue
The record is no longer available at this source.
Source Database: National Cancer Institute at Frederick
Genetic Background:
Affected Genes: Kirsten rat sarcoma viral oncogene homolog
Genomic Alteration: targeted mutation 4; Tyler Jacks
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: Kirsten rat sarcoma viral oncogene homolog; congenic strain: Kras
Proper citation: RRID:IMSR_NCIMR:01XJ6 Copy
Issue Issue
https://www.jax.org/strain/006608
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: Immunoglobulin heavy chain (gamma polypeptide)|transgene insertion 4; Christopher C Goodnow|immunoglobulin heavy constant mu
Genomic Alteration: transgene insertion 4; Christopher C Goodnow|targeted mutation 1; University of Cologne
Availability: embryo
References:
Synonyms: NOD.IgHEL.IgH-/-. NOD.Cg-Igh-6
Notes: gene symbol note: Immunoglobulin heavy chain (gamma polypeptide)|transgene insertion 4; Christopher C Goodnow|immunoglobulin heavy constant mu; mutant strain|congenic strain: Ighg|Tg(IghelMD4)4Ccg|Ighm
Proper citation: RRID:IMSR_JAX:006608 Copy
Issue
https://www.jax.org/strain/006825
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
References:
Synonyms:
Notes: gene symbol note: Fas cell surface death receptor; coisogenic strain|mutant strain: Fas
Proper citation: RRID:IMSR_JAX:006825 Copy
Issue
https://www.jax.org/strain/007082
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: tumor necrosis factor
Genomic Alteration: targeted mutation 1; George Kollias
Availability: sperm
References:
Synonyms:
Notes: gene symbol note: tumor necrosis factor; congenic strain: Tnf
Proper citation: RRID:IMSR_JAX:007082 Copy
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