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https://www.lerner.ccf.org/cores/biorobotics/

Core provides biomechanical testing of biological structures and biomaterials. Allows investigators to conduct research of mechanical properties of existing biological structures and constructs, as well as to quantify potential for new technologies and clinical advancements. Robotic simulators are built around the simVITRO software platform and are designed for in vitro simulation of major joints including knee, spine, foot, ankle, hip, shoulder, elbow, wrist and more. Provides testing capabilities for range of biomechanical modalities and will offer expert advice and support for development of new test protocols, innovative techniques for instrumentation and data collection. Modalities include tissues, joints, and multi-articular units, such as foot or spine segments.

Proper citation: Cleveland Clinic Lerner Research Institute BioRobotics and Mechanical Testing Core Facility (RRID:SCR_026849) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/eppley/cmtdd/cores/scst.html

Core offers spatial omics processing on many different tissue types. Facility provides instrumnets including Bruker's GeoMx DSP ready for launch with anticipated launch of 10x Visium. Offers expert collaboration from project design to data handoff. Core has established workflows with additional shared resources on UNMC campus to allow for expertise throughout entire project.

Proper citation: University of Nebraska Medical Center Single Cell and Spatial Transcriptomics Core Facility (RRID:SCR_026860) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/electron-microscopy.php

Core performs routine transmission and scanning Electron Microscopy and all kinds of immune Electron Microscopy, correlative light electron microscopy, three-dimensional EM (3DEM), quantitative stereological evaluation of data and more.

Proper citation: Cancer Research Institute IFOM EMCT Electron Microscopy Cells & Tissues Core Facility (RRID:SCR_026863) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/mechanomedicine.php

Core focuses on development of innovative biomedical technologies and devices for cancer research as well as biomedical applications using microfabrication and 3D printing.

Proper citation: Cancer Research Institute IFOM CERD Cancer Engineering R&D Core Facility (RRID:SCR_026862) Copy   

•   Source: SciCrunch Registry

https://www.ifom.eu/en/cancer-research/technological-units/preclinical-models.php

Specialized laboratory designed for growth, maintenance, and experimentation of living cells under controlled conditions. This facility is used in various fields such as biomedical research, drug development, and supports the culture of primary cells, immortalized cell lines, human-induced pluripotent stem cells (hiPSCs), and organoids, among others.

Proper citation: Cancer Research Institute IFOM CPM Cellular And Preclinical Models Core Facility (RRID:SCR_026864) Copy   

•   Source: SciCrunch Registry

https://www.uoflsequencing.com/services-2-1

Provides genomic sequencing services including next-generation sequencing (NGS), single-cell analysis, and spatial transcriptomics. Offers advanced short-read and long-read sequencing technologie including our status as a PacBio Certified Service Provider.

Proper citation: University of Louisville Sequencing Technology Center Genomics Services Core Facility (RRID:SCR_027013) Copy   

•   Source: SciCrunch Registry

https://cpl.ucdavis.edu/

Core is veterinary diagnostic laboratory and research pathology core. Provides laboratory animal diagnostics, clinical and health surveillance screening necessary for the care and use of animals in research, and expert pathology support for basic and translational research.

Proper citation: University of California Davis Comparative Pathology Laboratory Core Facility (RRID:SCR_027014) Copy   

•   Source: SciCrunch Registry

https://imb.uq.edu.au/microscopy

Microscopy Facility supports cancer research, cell and developmental biology, and cross-disciplinary studies spanning molecular mechanisms to translational applications. Houses imaging platforms including widefield, confocal, multi-photon, super-resolution, spinning disk, and light sheet systems. Enables advanced modalities such as TIRF, FRET, STED, SHG/THG, and FLIM for detailed exploration of cell behaviour and microenvironments. Facility staff offer training, expert consultation, image analysis support, and troubleshooting.

Proper citation: University of Queensland Institute for Molecular Bioscience Advanced Microscopy Core Facility (RRID:SCR_026841) Copy   

•   Source: SciCrunch Registry

https://bibraincancer.umich.edu/core/high-plex-immunocytochemistry-core/

Core utilizes Akoya PhenoCycler-Fusion to enable high-plex spatial phenotyping of whole tissue slides at single-cell resolution.

Proper citation: University of Michigan Bioinnovation in Brain Cancer High-Plex Immunocytochemistry Core Facility (RRID:SCR_026843) Copy   

•   Source: SciCrunch Registry

https://www.rogelcancercenter.org/research/shared-resources-and-cores/single-cell-analysis-core-overview

Provides expertise through experimental design consultations,cell isolation,single cell analytics (RNA, DNA, protein),biomarker validation,novel statistical and bioinformatics analyses. Services include Single cell targeted gene expression, Single cell RNA Seq, Single cell DNA Seq, Tissue sectioning, Tissue spatial analysis, Spatial transcriptomics and proteomics.

Proper citation: University of Michigan Rogel Cancer Center Single Cell Spatial Analysis Shared Resource Core Facility (RRID:SCR_026842) Copy   

•   Source: SciCrunch Registry

https://www.mdanderson.org/research/research-resources/core-facilities/research-histology-core-laboratory-rhcl.html

Core supports basic and clinical research by providing histological and molecular expertise, technical support and consultation to research investigators. Provides histological, molecular and consultation services. Services are performed by American Society of Clinical Pathology certified histologists with expertise in routine histology, whole slide scanning, image and digital analysis, pathology services, immunohistochemistry, tissue microarray, bone histomorphometry, Visium preparations and RNAscope single and co-detection assays.

Proper citation: University of Texas MD Anderson Research Histology Core Facility (RRID:SCR_026932) Copy   

•   Source: SciCrunch Registry

https://www.cogentech.it/genomic_unit.php

Cogentech's Genomic Core Facility (GU) provides professional support for workflow of research projects, from counseling on experimental design to functional interpretation of results. Support includes identification of the most suitable methodology to achieve the experimental aim, quality control of nucleic acid, generation of indexed fragment library, sequencing according to experimental needs and bioinformatic support for selected applications. Customized protocols can be set-up as well. Sequencing data are delivered using a password protected user-friendly web interface. The laboratory is ISO9001 certified.

Proper citation: IFOM ETS Cogentech GU Genomics Core Facility (RRID:SCR_026935) Copy   

•   Source: SciCrunch Registry

https://www.cogentech.it/histology.php

Cogentech's Histopathology (HP) Core Facility provides services including consultation, tissue trimming and embedding, cutting, staining, photographic documentation for the evaluation and characterization of normal and pathological tissues. Provides Optimization of protocols for new stains or biological specimen.The laboratory is ISO9001 certified.

Proper citation: IFOM ETS Cogentech HP Histopathology Core Facility (RRID:SCR_026934) Copy   

•   Source: SciCrunch Registry

https://www.cogentech.it/integrated-genomics.php

Cogentech's Integrated Genomics Core Facility (IGU) consists of units: Molecular Biology and Sequencing, Histopathology and Bioinformatics. Molecular Biology group provides expertise in various fields of application: nucleic acid extraction from different matrices, ddPCR and various types of sequencing (customised gene panels, Lowpass WGS, WES, WGS, total RNA-Seq, mRNA Seq, TCR-Seq, 16S Metagenomic Seq, ATAC-Seq, genome-wide methylation profiling). Bioinformatics unit provides pipelines for analysis of data produced by all sequencing workflows. In addition, it provides its expertise for implementation and development of customised pipelines. Histopathology unit offers services for slide preparation and staining, image digitisation and laser-capture microdissection. The laboratory is ISO9001 certified.

Proper citation: IFOM ETS Cogentech IGU Integrative Genomics Core Facility (RRID:SCR_026938) Copy   

•   Source: SciCrunch Registry

https://ccic.osu.edu/nmr

Advanced high-field NMR facility combines many capabilities spanning solution and solid state NMR, high sensitivity cryoprobes, ultrafast spinning MAS probes, as well as Dynamic Nuclear Polarization.

Proper citation: Ohio State University Campus Chemical Instrument Center NMR Core Facility (RRID:SCR_027162) Copy   

•   Source: SciCrunch Registry

https://research.vcu.edu/cores/structural-biology/cryo-em/

Facility offers sample preparation, visualization and analysis for high resolution 3D reconstruction of frozen-hydrated proteins and macromolecular complexes. Facility is endowed with Thermofisher Scientific Tundra cryo-electron microscope, Vitrobot Mark IV cryo-plunger, Pelco easyGlow glow discharge unit, Denton DV 502B evaporator, and linux server dedicated to image processing.

Proper citation: Virginia Commonwealth University Cryo-Electron Microscopy Core Facility (RRID:SCR_027178) Copy   

•   Source: SciCrunch Registry

https://czt.amu.edu.pl/cytomika-i-analiza-komorkowa/

Core is utilized in medical biotechnology and in research focused on mammalian cells. Offers analyzing of impact of new drugs and pharmaceuticals on individual cells in vitro. Provides sorting of cell populations with desired characteristics, including fluorescent dye-stained cell sorting (FACS) analysis of cell populations for presence of specific factors, e.g. introduced fluorescent protein, surface markers, DNA content determining the size, granulation and shape of animal and other cells.

Proper citation: Adam Mickiewicz University Cytometry Laboratory Core Facility (RRID:SCR_027177) Copy   

•   Source: SciCrunch Registry

https://cores.research.utdallas.edu/genome-center/

Core provides library prep and NGS services using Illumina NextSeq 2000. Our services include sample QC, DNA, RNA bulk sequencing, single cell sequencing, and Sanger sequencing.

Proper citation: University of Texas at Dallas UTD Genome Center Core Facility (RRID:SCR_027149) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/pharmacy/about/facilities/sop-nuclear-magnetic-resonance-nmr-facility

Core designed for range of solution-state pharmaceutical and biological chemistry applications. Facility is equipped with 600 MHz magnet equipped with high-throughput autosampler and QCI-F cryoprobe optimised for 1H and 19F sensitivity, and 400 MHz magnet dedicated to routine chemistry applications. Facility is also operating ligand-observed 19F-fragment library screening service for drug discovery.

Proper citation: University College London School of Pharmacy Nuclear Magnetic Resonance Core Facility (RRID:SCR_027123) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/atc-core-labs/mass-spectrometry-proteomics-core

Core provides services including project evaluation and design, sample processing and biochemical purifications, mass spectrometry measurements, data processing, and bioinformatics analysis performed by the experienced core personnel.

Proper citation: Baylor College of Medicine BCM Mass Spectrometry Proteomics Core Facility (RRID:SCR_027015) Copy   

•   Source: SciCrunch Registry