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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MolProbity
 
Resource Report
Resource Website
5000+ mentions
MolProbity (RRID:SCR_014226) software resource, web application A structure-validation web application which provides an expert-system consultation about the accuracy of a macromolecular structure model, diagnosing local problems and enabling their correction. MolProbity works best as an active validation tool (used as soon as a model is available and during each rebuild/refine loop) and when used for protein and RNA crystal structures, but it may also work well for DNA, ligands and NMR ensembles. It produces coordinates, graphics, and numerical evaluations that integrate with either manual or automated use in systems such as PHENIX, KiNG, or Coot. web application, consultation, macromolecular structure, structure validation, macromolecular crystallography is listed by: SoftCite
is related to: Phenix
is related to: Coot
has parent organization: Duke University; North Carolina; USA
Howard Hughes Medical Institute Predoctoral Fellowship ;
NIGMS GM-15000;
NIGMS GM-61302
DOI:10.1107/S0907444909042073 Acknowledgement requested, Requires Java and Javascript https://www.phenix-online.org/documentation/reference/molprobity_tool.html SCR_014226 2026-02-12 09:45:56 6313
SyStat
 
Resource Report
Resource Website
1000+ mentions
SyStat (RRID:SCR_010455) SyStat software resource, commercial organization A commercial software tool for statistical analysis. statistics is listed by: SoftCite nlx_157643 SCR_010455 2026-02-12 09:45:20 1101
GeneSpring GX
 
Resource Report
Resource Website
1000+ mentions
GeneSpring GX (RRID:SCR_010972) GeneSpring GX software resource, commercial organization Powerful, accessible statistical tools for fast visualization and analysis of microarrays - expression arrays, miRNA, exon arrays and genomics copy number data. is listed by: OMICtools
is listed by: SoftCite
Commercial license OMICS_00853 SCR_010972 2026-02-12 09:45:36 1816
Openlab
 
Resource Report
Resource Website
1000+ mentions
Openlab (RRID:SCR_012158) Openlab software resource, commercial organization A software package for performing 2D microscope image processing and integrating and controlling a diverse array of instrumentation in a laboratory environment. The software suite has four basic areas of operation acquisition, image presentation, and storage, analysis, and automation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. fluorescence imaging, cell biology is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE rid_000096 SCR_012158 2026-02-12 09:45:36 1133
SigmaPlot
 
Resource Report
Resource Website
10000+ mentions
SigmaPlot (RRID:SCR_003210) SigmaPlot software resource, commercial organization Statistical analysis and scientific graphing software for Windows OS. statistics, windows, graph, data analysis is listed by: SoftCite Commercial license SciRes_000184 SCR_003210 sigma plot 2026-02-12 09:43:33 17371
University of Texas at Austin; Texas; USA
 
Resource Report
Resource Website
1+ mentions
University of Texas at Austin; Texas; USA (RRID:SCR_005900) UT Austin institution, university A major university is related to: LungMap
is related to: RobotReviewer
has parent organization: University of Texas System; Texas; USA
is parent organization of: Academic Seismic Portal at UTIG
is parent organization of: FUGOID: a Database for Functional Genomics of Organelle Introns
is parent organization of: Aptamer Database - The Ellington Lab
is parent organization of: Poldracklab Portal
is parent organization of: Synapse Web Reconstruct
is parent organization of: Cognitive Atlas
is parent organization of: Synapse Web
is parent organization of: DigiMorph
is parent organization of: Amino Acid-Nucleotide Interaction Database
is parent organization of: VolumeRover
is parent organization of: Phenologs
is parent organization of: NeuroSynth
is parent organization of: Open Proteomics Database
is parent organization of: University of Texas at Austin College of Pharmacy
is parent organization of: University of Texas at Austin Labs and Facilities
is parent organization of: Texas Advanced Computing Center
is parent organization of: Aging Status and Sense of Control (ASOC)
is parent organization of: HumanNet
is parent organization of: Culture Collection of Algae at the University of Texas
is parent organization of: CiteAs
is parent organization of: University of Texas at Austin Genomic Sequencing and Analysis Core Facility
is parent organization of: University of Texas at Austin Biological Mass Spectrometry Proteomics Core Facility
is parent organization of: University of Texas at Austin Microscopy and Flow Cytometry Core Facility
is parent organization of: University of Texas at Austin Biomedical Imaging Center Core Facility
is parent organization of: University of Texas at Austin Mouse Genetic Engineering Core Facility
is parent organization of: University of Texas at Austin Biomedical Research Computing Core Facility
is parent organization of: University of Texas at Austin Computational Biology and Bioinformatics Core Facility
is parent organization of: University of Texas at Austin Cryo Electron Microscopy Core Facility
is parent organization of: University of Texas at Austin Advanced Protein Therapeutics Core Facility
is parent organization of: SoftCite
is parent organization of: University of Texas at Austin Shared Instrumentation Facility
grid.89336.37 https://ror.org/00hj54h04 SCR_005900 University of Texas at Austin 2026-02-12 09:44:08 5
Strelka
 
Resource Report
Resource Website
100+ mentions
Strelka (RRID:SCR_005109) Strelka software resource, commercial organization THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 7,2024. Software for somatic single nucleotide variant (SNV) and small indel detection from sequencing data of matched tumor-normal samples. The method employs a novel Bayesian approach which represents continuous allele frequencies for both tumor and normal samples, whilst leveraging the expected genotype structure of the normal. This is achieved by representing the normal sample as a mixture of germline variation with noise, and representing the tumor sample as a mixture of the normal sample with somatic variation. A natural consequence of the model structure is that sensitivity can be maintained at high tumor impurity without requiring purity estimates. The method has superior accuracy and sensitivity on impure samples compared to approaches based on either diploid genotype likelihoods or general allele-frequency tests. single nucleotide variant, indel, somatic snv, next-generation sequencing, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Illumina
Cancer, Tumor, Normal PMID:22581179
PMID:30013048
biotools:strelka https://bio.tools/strelka
https://github.com/Illumina/strelka/
https://sources.debian.org/src/strelka/
SCR_005109 2026-02-12 09:44:00 261
BLASTN
 
Resource Report
Resource Website
10000+ mentions
BLASTN (RRID:SCR_001598) BLASTn data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Web application to search nucleotide databases using a nucleotide query. Algorithms: blastn, megablast, discontiguous megablast. nucleotide, alignment, compare, sequence, genome, blast, transcript, dna sequence is listed by: OMICtools
is listed by: SoftCite
has parent organization: NCBI
works with: Seek and Blastn
works with: RMBlast
PMID:17666756
PMID:18567917
Free, Freely available nlx_153932, OMICS_00990 http://blast.ncbi.nlm.nih.gov/Blast.cgi?PROGRAM=blastn&PAGE_TYPE=BlastSearch&LINK_LOC=blasthome SCR_001598 NCBI BLASTN, Nucleotide Blast, Standard Nucleotide BLAST 2026-02-13 10:54:53 19679
Sequencher
 
Resource Report
Resource Website
1000+ mentions
Sequencher (RRID:SCR_001528) Sequencher sequence analysis software sequence analysis software, data processing software, data analysis software, software application, software resource Software for Next-Generation DNA sequencing, Sanger DNA analysis, and RNA sequencing. It contains sequence analysis tools which include reference-guided alignments, de novo assembly, variant calling, and SNP analyses. It has integrated the Cufflinks suite for in-depth transcript analysis and differential gene expression of RNA-Seq data. dna, sequencing, sequence analysis software, NGS, sanger, data visualization is listed by: OMICtools
is listed by: SoftCite
Available for download OMICS_01817 http://genecodes.com/sequencher-features SCR_001528 Sequencher sequence analysis software 2026-02-13 10:54:53 4965
PLINK
 
Resource Report
Resource Website
10000+ mentions
Issue
PLINK (RRID:SCR_001757) data processing software, data analysis software, software toolkit, software application, software resource Open source whole genome association analysis toolset, designed to perform range of basic, large scale analyses in computationally efficient manner. Used for analysis of genotype/phenotype data. Through integration with gPLINK and Haploview, there is some support for subsequent visualization, annotation and storage of results. PLINK 1.9 is improved and second generation of the software. gene, genetic, genomic, genotype, phenotype, copy number variant, whole-genome association, population, linkage analysis, whole-genome association study, data management, summary statistics, population stratification, association analysis, identity-by-descent estimation is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: SoftCite
is related to: Whap
is related to: PLINK/SEQ
is related to: Haploview
is related to: MendelIHT.jl
PMID:17701901
DOI:10.1086/519795
Free, Available for download, Freely Available nlx_154200, OMICS_00206, SCR_021271 https://zzz.bwh.harvard.edu/plink/
https://www.cog-genomics.org/plink/1.9/general_usage#cite
https://sources.debian.org/src/plink/
http://pngu.mgh.harvard.edu/~purcell/plink/ SCR_001757 PLINK 1.9, PLINK/SEQ, plink - Whole genome association analysis toolset 2026-02-13 10:54:55 15344
GenABEL
 
Resource Report
Resource Website
500+ mentions
GenABEL (RRID:SCR_001842) software resource, software library, software toolkit THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. R software library for genome-wide association analysis for quantitative, binary and time-till-event traits. r, genome-wide association, single nucleotide polymorphism is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: SoftCite
Centre for Medical Systems Biology; Netherlands ;
Netherlands Genomics Initiative ;
Netherlands Organisation for Scientific Research ;
Russian Foundation for Basic Research
PMID:17384015
DOI:10.1186/1471-2105-11-134
DOI:10.1093/bioinformatics/btm108
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154328, OMICS_00234 http://mga.bionet.nsc.ru/~yurii/ABEL/GenABEL/
https://cran.r-project.org/web/packages/GenABEL/index.html
https://sources.debian.org/src/probabel/
SCR_001842 GenABEL package, R/GENABEL 2026-02-13 10:54:56 506
FreeSurfer
 
Resource Report
Resource Website
10000+ mentions
FreeSurfer (RRID:SCR_001847) FreeSurfer data visualization software, data processing software, software application, software resource, image analysis software Open source software suite for processing and analyzing human brain MRI images. Used for reconstruction of brain cortical surface from structural MRI data, and overlay of functional MRI data onto reconstructed surface. Contains automatic structural imaging stream for processing cross sectional and longitudinal data. Provides anatomical analysis tools, including: representation of cortical surface between white and gray matter, representation of the pial surface, segmentation of white matter from rest of brain, skull stripping, B1 bias field correction, nonlinear registration of cortical surface of individual with stereotaxic atlas, labeling of regions of cortical surface, statistical analysis of group morphometry differences, and labeling of subcortical brain structures.Operating System: Linux, macOS. processing, analysis, human, brain, MRI, image, reconstruction, cortical, surface, fMRI, data is used by: Wisconsin Cortical Thickness Analysis (CTA) Toolbox
is used by: freesurfR
is used by: Automatic Analysis
is used by: NHP Freesurfer
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is listed by: Debian
is listed by: SoftCite
is related to: PySurfer
is related to: RFT FDR
is related to: FMRLAB
is related to: TRACULA
is related to: BASH4RfMRI
has parent organization: Harvard University; Cambridge; United States
has plug in: JOSA
works with: NIAG Addiction Data
NCRR U24 RR021382;
NINDS R01 NS052585;
NCRR RR014075
PMID:22248573 Free, Available for download, Freely available nif-0000-00304 https://sources.debian.org/src/freesurfer/
http://www.nitrc.org/projects/freesurfer
http://surfer.nmr.mgh.harvard.edu/fswiki/DownloadAndInstall
SCR_001847 2026-02-13 10:54:56 11817
AStalavista
 
Resource Report
Resource Website
50+ mentions
AStalavista (RRID:SCR_001815) AStalavista data analysis service, analysis service resource, production service resource, service resource, software resource Tool that extracts and displays alternative splicing (AS) events from a given genomic annotation of exon-intron gene coordinates. By comparing all given transcripts, it detects the variations in their splicing structure and identifies all AS events (like exon skipping, alternate donor, etc) by assigning to each of them an AS code. It provides a visual summary of the AS landscape in the analyzed dataset, the possibility to browse the results on the UCSC website or to download them in GTF or ASTA format. You can use AStalavista for any genome by providing your own annotation set, the identifier of your gene(s) of interest, or analyze the AS landscape of reference annotation datasets like Gencode, RefSeq, Ensembl, FlyBase, etc. alternative splicing event, alternative splicing, visualization, genome, transcript is listed by: OMICtools
is listed by: SoftCite
has parent organization: Center for Genomic Regulation; Barcelona; Spain
PMID:17485470 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01943 http://genome.imim.es/astalavista
http://genome.crg.es/astalavista/
SCR_001815 Alternative Splicing transcriptional landscape visualization tool 2026-02-13 10:54:55 83
Fiji
 
Resource Report
Resource Website
10000+ mentions
Fiji (RRID:SCR_002285) Fiji data processing software, source code, software application, image processing software, software resource Software package as distribution of ImageJ and ImageJ2 together with Java, Java3D and plugins organized into coherent menu structure. Used to assist research in life sciences. imaging, microscopy, windows, linux, java, mac osx, bio.tools uses: Fiji/ImageJ
is used by: MuscleJ
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: ImageJ
is related to: SynapseLocator
is related to: Golddigger
is related to: Analyze Spheroid Cell Invasion In 3D Matrix
has parent organization: Max Planck Institute of Molecular Cell Biology and Genetics; Dresden; Germany
has plug in: BioVoxxel Toolbox
has plug in: imctools
has plug in: Big Data Processor
has plug in: Sholl Analysis
has plug in: SAIBR
has plug in: TWOMBLI
PMID:22743772 Free, Available for download, Freely available, Acknowledgement requested SciRes_000137, biotools:Fiji https://github.com/fiji/fiji
https://bio.tools/Fiji
SCR_002285 Fiji is just ImageJ 2026-02-13 10:55:00 37202
Pathway Commons
 
Resource Report
Resource Website
10+ mentions
Pathway Commons (RRID:SCR_002103) PC web service, data or information resource, data access protocol, software resource, database Database of publicly available pathways from multiple organisms and multiple sources represented in a common language. Pathways include biochemical reactions, complex assembly, transport and catalysis events, and physical interactions involving proteins, DNA, RNA, small molecules and complexes. Pathways were downloaded directly from source databases. Each source pathway database has been created differently, some by manual extraction of pathway information from the literature and some by computational prediction. Pathway Commons provides a filtering mechanism to allow the user to view only chosen subsets of information, such as only the manually curated subset. The quality of Pathway Commons pathways is dependent on the quality of the pathways from source databases. Pathway Commons aims to collect and integrate all public pathway data available in standard formats. It currently contains data from nine databases with over 1,668 pathways, 442,182 interactions,414 organisms and will be continually expanded and updated. (April 2013) biological pathway, pathway, molecule, biopax, standard exchange format, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: cPath
is related to: Biological General Repository for Interaction Datasets (BioGRID)
is related to: IntAct
is related to: Reactome
is related to: MINT
is related to: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is related to: Cancer Cell Map
is related to: HPRD - Human Protein Reference Database
is related to: Integrated Molecular Interaction Database
is related to: Pathway Interaction Database
is related to: CHEBI
is related to: UniProt
is related to: PANTHER
is related to: WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
has parent organization: University of Toronto; Ontario; Canada
NHGRI P41HG004118;
NIGMS 2R01GM070743-06;
NIGMS 1T32 GM083937;
Cancer Biomedical Informatics Grid
PMID:21071392 Free, Freely available nif-0000-20884, biotools:PathwayCommons_web_service_API https://bio.tools/PathwayCommons_web_service_API SCR_002103 2026-02-13 10:54:58 14
SAMTOOLS
 
Resource Report
Resource Website
10000+ mentions
SAMTOOLS (RRID:SCR_002105) SAMtools sequence analysis software, data processing software, data analysis software, software toolkit, software application, software resource Original SAMTOOLS package has been split into three separate repositories including Samtools, BCFtools and HTSlib. Samtools for manipulating next generation sequencing data used for reading, writing, editing, indexing,viewing nucleotide alignments in SAM,BAM,CRAM format. BCFtools used for reading, writing BCF2,VCF, gVCF files and calling, filtering, summarising SNP and short indel sequence variants. HTSlib used for reading, writing high throughput sequencing data. Samtools, BCFtools, HTSlib, next generation sequencing, nucleotide alignments, sequence variant, genomic, c, perl, read, alignment, nucleotide, sequence, data, process, sam, bam, cram, vcf, bcf, bio.tools is used by: deFuse
is used by: Short Read Sequence Typing for Bacterial Pathogens
is used by: ROSE
is used by: Fcirc
is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: SNVer
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Platypus
is related to: shovill
is related to: pysam
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
is parent organization of: SAMtools/BCFtools
is required by: RelocaTE
is required by: Wessim
is required by: SL-quant
is required by: smMIPfil
Wellcome Trust ;
NHGRI U54 HG002750
PMID:19505943
PMID:21903627
DOI:10.1093/bioinformatics/btp352
Free, Available for download, Freely available SCR_018682, biotools:samtools, OMICS_01074, nlx_154607, OMICS_00090 https://github.com/samtools/samtools
https://github.com/samtools/htslib
https://bio.tools/samtools
https://sources.debian.org/src/samtools/
http://samtools.sourceforge.net/ SCR_002105 samtools, Samtools, Sequence Alignment Map TOOLS, SAMtools, SAM tools 2026-02-13 10:54:58 30156
Glide
 
Resource Report
Resource Website
10+ mentions
Glide (RRID:SCR_000187) Glide software resource, simulation software, software application Software package which approximates a complete search of the conformational, orientational, and positional space of the ligand in a given receptor. Used in drug development for predicting protein ligand binding modes and ranking ligands via high throughput virtual screening. ligand, receptor, docking, computation, virtual, screening, drug, discovery is listed by: OMICtools
is listed by: SoftCite
has parent organization: Schrodinger
works with: Ligprep
PMID:18428795 Restricted OMICS_01601 SCR_000187 2026-02-13 10:54:37 15
IGOR Pro
 
Resource Report
Resource Website
500+ mentions
IGOR Pro (RRID:SCR_000325) data visualization software, data processing software, authoring tool, data analysis software, software application, software resource Software used for visualizing and graphing data, image processing, and programming. It is designed for use by scientists and engineers and supports large data sets, evenly spaced data, and various data import formats. The software includes a suite of image processing operations for image filtering, manipulation, and quantification and is completely programmable. commercial tool, electrophysiology, authoring tool, data visualization software, image processing, publication quality, interactive is listed by: SoftCite Restricted nlx_156887, SCR_014216 SCR_000325 Igor Pro - Technical graphing and data analysis, Igor Software 2026-02-13 10:54:39 661
Taverna
 
Resource Report
Resource Website
10+ mentions
Taverna (RRID:SCR_004437) Taverna software resource, workflow software, data processing software, software application An open source and domain independent Workflow Management System ����?? a suite of tools used to design and execute scientific workflows and aid in silico experimentation. Taverna Workbench now has support for service sets, offline workflow editing, workflow validation, improved workflow run monitoring, and the pausing and canceling of workflow runs. The command line tool allows you to run workflows outside of the workbench and is available as a stand-alone download or bundled with the Taverna Workbench 2.2.0 download. The Taverna suite is written in Java and includes the Taverna Engine (used for enacting workflows) that powers both the Taverna Workbench (the desktop client application) and the Taverna Server (which allows remote execution of workflows). Taverna is also available as a Command Line Tool for a quick execution of workflows from a terminal. Taverna 2.2.0 includes * Copy/paste, shortcuts, undo/redo, drag and drop * Animated workflow diagram * Remembers added/removed services * Secure Web services support * Secure access to resources on the web * Up-to-date R support * Intermediate values during workflow runs * myExperiment integration * Excel and csv spreadsheet support * Command line tool is listed by: OMICtools
is listed by: SoftCite
is related to: myExperiment
is related to: U-Compare
is related to: Taverna Knowledge Blog
is related to: AIDA Toolkit
is related to: Knowledge Blog
has parent organization: University of Manchester; Manchester; United Kingdom
OMII-UK ;
EPSRC ;
BBSRC ;
Microsoft ;
ESRC ;
JISC
PMID:18337261
PMID:23640334
Open unspecified license nlx_43462, OMICS_01146 SCR_004437 2026-02-13 10:55:26 30
STAR
 
Resource Report
Resource Website
10000+ mentions
STAR (RRID:SCR_004463) data processing software, alignment software, software application, software resource, image analysis software Software performing alignment of high-throughput RNA-seq data. Aligns RNA-seq reads to reference genome using uncompressed suffix arrays. RNA-seq data, alignment, RNA-seq reads alignment, reference genome, using uncompressed suffix arrays, bio.tools is used by: STARsolo
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
NHGRI U54 HG004557 PMID:23104886
DOI:10.1093/bioinformatics/bts635
biotools:star, OMICS_01254, SCR_015899 https://github.com/alexdobin/STAR
https://bio.tools/star
https://sources.debian.org/src/rna-star/
SCR_004463 Spliced Transcripts Alignment to Reference, Spliced Transcripts Alignment to a Reference (STAR), rna-star, ultrafast universal RNA-seq aligner 2026-02-13 10:55:26 22809

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