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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
DFCI RNA Interference Screening Facility
 
Resource Report
Resource Website
DFCI RNA Interference Screening Facility (RRID:SCR_009755) core facility, access service resource, service resource Core facility that provides the following services: Genome-scale screening of lentiviral human and mouse shRNA libraries.

The RNAi Screening Facility provides investigators with access to RNAi reagents and high-throughput screening technology. Lentiviral-based RNAi constructs against the human and mouse genomes are provided by the RNAi Consortium of the Broad Institute, and can be used to transduce a wide range of target cells, including primary and non-dividing cells. The Facility provides reagents, equipment, and technical expertise to design, optimize, and perform cell-based, arrayed lentiviral RNAi screens. Additionally, lentiviral RNAi constructs against individual genes can be requested.
viral infection is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156215 SCR_009755 2026-02-14 02:08:00 0
DFCI Shannon McCormack Advanced Molecular Diagnostics Laboratory
 
Resource Report
Resource Website
DFCI Shannon McCormack Advanced Molecular Diagnostics Laboratory (RRID:SCR_009756) core facility, access service resource, service resource The Molecular Diagnostics Laboratory provides such research services as microRNA expression profiling, human cell line identity verification, mutation detection for clinical research studies, and specimen processing for clinical research studies to investigators at the Dana Farber Cancer Institute, as well as to investigators at other institutions. Consultation on experimental design and assistance with data analysis are also available. is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156216 SCR_009756 2026-02-14 02:07:34 0
Dana-Farber Cancer Institute Molecular Biology Core Facility
 
Resource Report
Resource Website
1+ mentions
Dana-Farber Cancer Institute Molecular Biology Core Facility (RRID:SCR_009754) MBCF at DFCI core facility, access service resource, service resource Core offers services for genomic next-generation sequencing library preparation, sequencing and analysis applications including RNAseq, ChIPseq, ATACseq, CRISPR screening, whole genome methylation profiling, targeted resequencing, single-cell RNAseq, exome sequencing, and more. Performs bioinformatics analysis such as integration of multi-omics datasets or specialized analyses. Genomics core technology platforms include Illumina NovaSeq6000, NextSeq500s, MiSeqs, MiniSeq. High throughput sample preparation is performed on Beckman Coulter Biomek FX and i7 systems. Low throughput samples are prepared by technical staff. Next generation sequencing, RNAseq, ChIPseq, ATACseq, CRISPR, analysis, dataset, genomics, ABRF is listed by: Eagle I
is listed by: ABRF CoreMarketplace
has parent organization: Dana-Farber Cancer Institute
Open nlx_156214, SCR_018264, ABRF_57 https://coremarketplace.org/?FacilityID=57 http://harvard.eagle-i.net/i/0000012a-2512-3484-5617-794280000000 SCR_009754 , Dana-Farber Cancer Institute Molecular Biology Core Facilities, DFCI Molecular Biology Core Facilities 2026-02-14 02:07:27 1
DFCI Flow Cytometry Core Facility
 
Resource Report
Resource Website
1+ mentions
DFCI Flow Cytometry Core Facility (RRID:SCR_009751) core facility, access service resource, service resource Core facility that provides the following services: Cell Sorting.

The Flow Cytometry Core Facility provides sterile sorting and analysis of samples in support of research at DFCI. The core has 2 high-speed cell sorters, the BD FACSAria II SORP and BD FACSAria IIu with up to 12-color simultaneous detection utilizing multi-laser platforms. Sample populations can be sterile sorted into a variety of tubes or plates. The BD FACSAria II SORP and BD FACSAria IIu are both equipped with the Automated Cell Deposition Unit (ACDU) for sterile sinlge cell sorting into 96, 384 micro titer plates. The core presently has 2 analyzers, the BD LSRFortessa SORP and BD LSRII with up to 12-color simultaneous detection utilizing multi-laser platforms. The BD LSR II is also equipped with an HTS(high throughput sampler) for analyzing samples directly from 96 well micro titer plates as well as being able to run 5ml tubes. The Facility staff is available to assist researchers with their sorting and analysis needs. Researchers who would like to utilize the analyzers are trained so that they can analyze their experiments independently. The staff will assist with data acquisition and analysis as well as interpretation. They will also assist in experiment design and implementation as well as troubleshooting. Training sessions are available for researchers who would like to run their sorting experiments independently.
cellular assay is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156211 http://flowcytometry.dfci.harvard.edu/ SCR_009751 2026-02-14 02:08:00 1
DFCI Medical Arts Core Facility
 
Resource Report
Resource Website
DFCI Medical Arts Core Facility (RRID:SCR_009752) core facility, access service resource, service resource Core facility that provides the following services: Graphics services, All Research Related Photography.

Medical Arts Core DFCI offers complete services for Publications, Presentations and Advertising as follows: Custom/Computer Graphics illustrations, Design and Consulting full productions services, Photoshop training. Posters Productions/Brochure Printing on best selection of paper, canvas material and Backlit poster films. Lamination, LCD announcements creation and posting. Research Related Photography Equipment: * iMAC and PC computers * Posters printer * LCD electronic announcements TV units * Backlit Display units * Laminator * Scanner * Digital camera
photography is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156212 http://www.dana-farber.org/Research/Core-Facilities.aspx#medical SCR_009752 2026-02-14 02:07:34 0
DFCI Survey and Data Management Core
 
Resource Report
Resource Website
DFCI Survey and Data Management Core (RRID:SCR_009750) core facility, access service resource, service resource Core facility that provides the following services: Data collection, data entry and analysis, Database design, data management and process tracking, Qualitative data collection, management and analysis.

The Survey and Data Management Core (SDMC) provides efficient, high-quality survey data collection and management services and consultation to support the research needs of investigators and staff throughout the Harvard Medical research community. The Core, housed within the Center for Population Sciences at the Dana-Farber Cancer Institute, is dedicated to rigorous quantitative and qualitative survey data collection and management.
research subject private information management, data entry, data analysis, data acquisition, database development, data management is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156217 http://surveycore.org/
http://www.dana-farber.org/Research/Core-Facilities.aspx#data
SCR_009750 2026-02-14 02:07:27 0
DF/HCC Tumor Imaging Metrics Core Facility
 
Resource Report
Resource Website
DF/HCC Tumor Imaging Metrics Core Facility (RRID:SCR_009744) core facility, access service resource, service resource Core facility that provides the following services: Reporting and database management service of radiological data for clinical trials, Radiologic exam quality control service.

The mission of the Tumor Imaging Metrics Core (TIMC) is to provide standardized, consistent, longitudinal radiological measurements to evaluate therapeutic response for DF/HCC clinical trials. The TIMC - * Makes reliable, quantitative, longitudinal measurements (such as RECIST, WHO, SWOG, standardized uptake value (SUV) etc.) of lesions from serial MRI, CT, PET, and PET/CT scan images * Presents results of analyses on a password-protected secure web-based report * Provides an independent service, with verifiable measurement of treatment response for patients enrolled in cancer center trials * Serves as a centralized, computerized resource to facilitate efficient internal or external auditing Reliable tracking of changes in lesion size or metabolism is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Imaging Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.
database maintenance, data management, quality control is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156205 http://www.dfhcc.harvard.edu/core-facilities/tumor-imaging-metrics/
http://harvard.eagle-i.net/i/0000012c-ae0f-b032-02c0-2b6880000000
SCR_009744 DF/HCC Tumor Imaging Metrics Core 2026-02-14 02:08:03 0
DF/HCC Rodent Histopathology Core Facility
 
Resource Report
Resource Website
DF/HCC Rodent Histopathology Core Facility (RRID:SCR_009742) core facility, access service resource, service resource Core facility that provides the following services: Histopathology analysis service, Histopathologic diagnosis training service, Cryosectioning service, Rodent necropsy service, Paraffin sectioning service, Bacteria, fungi, and inclusion bodies histological staining service, Rodent tissue processing, Carbohydrate and mucoproteins histological staining service, Connective tissue and muscle histological staining service, Cytoplasmic granules histological staining service, Fats and lipids histological staining service, Hematologic and nuclear elements histological staining service, Nerve cells and fibers histological staining service, Equipment training service, Equipment access service.

The Rodent Histopathology Core was founded in 1999 as one of the pathology cores within the Dana-Farber/Harvard Cancer Center. The Core was established to provide high quality professional, technical, and educational pathology services. The ultimate goal of the facility has been to support investigator research that leads to the identification of pathologic processes in mice and can be directly translatable to human disease. The core provides an essential and unique service to the many Center members and labs invested in mouse research. While many commercial and academic histology services are available, no other service is available that offers comparable high quality service with rapid turn around time and highly experienced professional supervision. The educational mission of the Core also adds an important dimension.
histology, histological sample preparation, cryosectioning, tissue procurement, tissue sectioning, biological sample processing, tissue embedding is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156202 http://www.dfhcc.harvard.edu/core-facilities/rodent-histopathology-pathology/services/
http://genepath.med.harvard.edu/pathcore/
SCR_009742 2026-02-14 02:08:00 0
DF/HCC Pathology Specimen Locator
 
Resource Report
Resource Website
DF/HCC Pathology Specimen Locator (RRID:SCR_009741) core facility, access service resource, service resource PSL is a consultative Core with components in each of the five DF/HCC hospitals. We have established a web-based network of autonomous, distributed, searchable databases, which contain de-identified, coded, pathologic information on post-diagnostic, excess human materials (including frozen or paraffin-embedded tissues and bodily fluids). Standardized specimen core dataset includes age, gender, anatomic location, tissue type, and diagnoses. Access to the PSL is through the password-protected Harvard eCommons. Two types of generic PSL uses are envisioned: (1) Center members with eCommons accounts can quickly retrieve aggregated tissue availability information to determine the feasibility of a proposed study. (2) Approved investigators can discover and review materials from suitable, de-identified and coded cases online and then request the samples they want. is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156201 http://www.dfhcc.harvard.edu/core-facilities/pathology-specimen-locator-pathology/
http://genepath.med.harvard.edu/pathcore/
SCR_009741 2026-02-14 02:07:27 0
Dartmouth SYNERGY: Biomedical Informatics Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Biomedical Informatics Core (RRID:SCR_009771) Dartmouth BIC core facility, access service resource, service resource Core facility that provides the following services: Research Consulation: Informatics Research.

The Biomedical Informatics Core (BIC) offers clinical and translational investigators support on informatics tools for cohort discovery, data integration, data management, text mining and visual analytics. In addition, the BIC provides consultative services on integration of data systems and on procedures for research data security.
data management, computational modeling technique, image visualization and analysis, secure data storage is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156235 http://synergy.dartmouth.edu/research_core_bic.html SCR_009771 2026-02-14 02:08:01 0
Dartmouth SYNERGY: Bioregistry
 
Resource Report
Resource Website
Dartmouth SYNERGY: Bioregistry (RRID:SCR_009772) core facility, access service resource, service resource Currently under development, the SYNERGY Bioregistry is a centralized virtual biorepository that will integrate information about samples from existing and future biorepositories. The Bioregistry will comprise: A standardized data warehouse of information on existing research biorepositories at Dartmouth eSample, a research tool to allow tracking of specimens and integration with the Bioregistry Access to the Dartmouth freezer farm of large freezer storage units to support archived materials The Bioregistry will enhance access to a diverse array of biologic samples, allowing investigators to manage sample collection and storage based on individual project needs and enabling researchers to learn about existing samples that can be used to pursue new clinical and translational studies. Bioregistry Director: Margaret Karagas, PhD is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156236 http://synergy.dartmouth.edu/research_core_bioregistry.html SCR_009772 2026-02-14 02:07:35 0
Dartmouth Pathology Translational Research
 
Resource Report
Resource Website
Dartmouth Pathology Translational Research (RRID:SCR_009770) core facility, access service resource, service resource Core facility that provides the following services: Tissue collection, Histology services, Molecular pathology services, Pathologist consultation.

The Pathology Shared Resource (PSR) provides four primary services for NCCC investigators: # it partners researchers with appropriate pathologists to provide specific expertise matched to the needs of the research project; # it coordinates the procurement, preservation, and distribution of human tissues and cells for funded and developmental NCCC basic and clinical research; # it performs histologic, immunohistologic, and molecular diagnostic procedures including DNA sequencing SNP genotyping and quantitative gene expression analysis for NCCC researchers; and # it provides a GMP cell processing laboratory for the isolation/purification, manipulation, expansion and/or storage of cells derived from a patient''s/subject''s peripheral blood intended for autologous reinfusion. The Pathology Shared Resource is closely integrated with the anatomic pathology laboratory of Mary Hitchcock Memorial Hospital and provides a cost-effective mechanism for NCCC investigators to take advantage of the economic efficiencies provided by that high-volume facility. The Core is managed by the Norris Cotton Cancer Center as a shared resource on behalf of the university and is available to all investigators within the greater Dartmouth research community. This Shared Resource is supported by funds from the Norris Cotton Cancer Center Core Grant and is overseen by the EMTG, an oversight and advisory committee of the Cancer Center.
tissue procurement, immunohistochemistry assay, biological sample processing, histological sample preparation, histology, gene expression analysis assay, laser capture microdissection, dna sequencing, dna extraction, snp interrogation genotyping, rna extraction is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156233 http://cancer.dartmouth.edu/res/pathology.html SCR_009770 2026-02-14 02:07:27 0
Dartmouth SYNERGY: Recruitment and Retention Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Recruitment and Retention Core (RRID:SCR_009768) Dartmouth RCC core facility, access service resource, service resource Core facility that provides the following services: Comprehensive, Expert Recruitment and Retention support.

The Recruitment and Retention Core (RCC) helps investigators make their studies visible across Dartmouth and to the public to increase awareness of clinical study opportunities. RRC Director: Sheila B. Noone, PhD
community-based participatory research is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156240 http://synergy.dartmouth.edu/research_core_rrc.html SCR_009768 2026-02-14 02:07:35 0
Dartmouth SYNERGY: Research Design and Epidemiology Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Research Design and Epidemiology Core (RRID:SCR_009769) Dartmouth RDE core facility, access service resource, service resource The Research Design and Epidemiology Core (RDE) provides consultation and guidance to investigators at the earliest stages of their study design. is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156241 SCR_009769 2026-02-14 02:08:04 0
Dartmouth Institute for Health Policy and Clinical Practice: Data and Analytic Core
 
Resource Report
Resource Website
Dartmouth Institute for Health Policy and Clinical Practice: Data and Analytic Core (RRID:SCR_009764) Dartmouth DAC core facility, access service resource, service resource Core facility that provides the following services: Data and Analysis of large health care datasets.

The Data and Analytic Core (DAC) includes research analysts and programmers, research assistants, a data librarian, and a Director who reports to the Director of the Center for Health Policy Research and the DAC Advisory Committee. The DACs responsibilities are to maintain an extremely secure environment for health care datasets provided to Principal Investigators by the U.S. Centers for Medicare and Medicaid Services, state governments, and other organizations under data use agreements and licenses. The DAC works under the direction of faculty investigators who have specific permission to use the data to conducted research. The DAC consists of 15 analysts (and an additional 5 staff) with a combined 150 years of healthcare claims analytic experience and a mastery of a broad range of programming and statistical methods. New analysts undergo a comprehensive training program lasting the better part of 6 months to assure a strong foundation in Medicare data analytics.
data analysis is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156228 http://tdi.dartmouth.edu/initiatives/research/data-and-analytic-core SCR_009764 2026-02-14 02:07:35 0
Dartmouth Media Research Lab Shared Resource
 
Resource Report
Resource Website
Dartmouth Media Research Lab Shared Resource (RRID:SCR_009765) Dartmouth DMRL core facility, access service resource, service resource Core facility that provides the following services: Coding of data. The Dartmouth Media Research Lab (DMRL) specializes in the content coding of all types of media including movies, television programming and advertising. We have an extensive database of top box office hits from 1995 to the present. Past areas of research have included tobacco, alcohol, food, violence, and sexual activity. The team consists of two trained coders and a supervisor who ensures consistency and reliability. data transformation is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156229 SCR_009765 2026-02-14 02:08:04 0
Dartmouth Biostatistics Shared Resource
 
Resource Report
Resource Website
Dartmouth Biostatistics Shared Resource (RRID:SCR_009760) core facility, access service resource, service resource The primary mission of the Biostatistics Shared Resource (BSR) is to improve the statistical aspects of cancer research at Dartmouth by providing expert statistical collaboration for research projects of Cancer Center members. Because every aspect of cancer research involves data, all research programs potentially may require the participation of the BSR. Areas of special faculty expertise include clinical trial design, longitudinal data, statistical methods for genomics and managing data, measurement error methods, nonlinear dose response modeling, quality of life data, decision sciences, cost effectiveness analysis, and diagnostic test assessment. Faculty and staff offices are located on the 8th floor of the Rubin building at Dartmouth-Hitchcock Medical Center (DHMC). The BSR maintains an extensive statistical software library providing access to all major statistical analysis platforms. Server and network access are provided through Cancer Center administration, DHMC, and Dartmouth College. The BSR collaborates closely with other shared resources for project development and monitoring through the Office of Clinical Research, and the Integrative Biology and Experimental and Translational Models Shared Resources. is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156221 http://cancer.dartmouth.edu/res/biostatistics.html
biostat.hitchcock.org
SCR_009760 2026-02-14 02:07:35 0
Massachusetts Host-Microbiome Center
 
Resource Report
Resource Website
Massachusetts Host-Microbiome Center (RRID:SCR_009713) BWH, CHB, Gnotobiotic and Microbiology Core, core facility, access service resource, service resource The Center promotes further understanding of host-microbiome interactions in health and disease, emphasizing a focus on function to define causative effects of the microbiota in vivo and to harness this knowledge in developing new therapies, diagnostics and further commercial applications. laboratory animal care, mouse breeding, histology, tissue procurement, maintaining cell culture, material component identification is listed by: Eagle I Available to external user nlx_156173 http://metagenomics.partners.org/
http://www.hms.harvard.edu/hddc/services/gnotobiotic/
http://harvard.eagle-i.net/i/00000130-097b-7a38-de5a-673e80000000
SCR_009713 , Children's Hospital Boston Gnotobiotic and Microbiology Core, CHB 2026-02-14 02:07:34 0
BIDMC X-ray Crystallography Core
 
Resource Report
Resource Website
BIDMC X-ray Crystallography Core (RRID:SCR_009678) core facility, access service resource, service resource Core facility that provides the following services: X-ray crystallography service, X-ray crystallography reference database access service, X-ray crystallographic data analysis and processing service, Access to x-ray crystallography using synchrotron radiation, X-ray crystallography advising and consultation service.

The X-ray Crystallography Facility located at 99 Brookline Ave. (Research North) was recently established as a core to serve the needs of investigators in the BIDMC and Harvard Medical School community interested in using structural biology as a tool in their research.
x-ray crystallography assay is listed by: Eagle I nlx_156135 http://www.bidmc.org/Research/CoreFacilities/XrayCrystallographyCore.aspx SCR_009678 2026-02-14 02:07:58 0
CHB Epithelial Cell Biology Core
 
Resource Report
Resource Website
CHB Epithelial Cell Biology Core (RRID:SCR_009712) core facility, access service resource, service resource Core facility that provides the following services: Cell culture services, Cell line freezing, Transient transfection, FACS Analysis, n-Counter mRNA analysis. Provides technologies and resources required for studies on polarized epithelial cells that line mucosal surfaces. We provide specialized epithelial cell culture and gene manipulation services, customized materials and instrumentation, expert know-how, and training to facilitate structural and functional studies on polarized epithelial cell culture systems or mucosal intestinal tissue in situ. maintaining cell culture, low temperature freezing, transfection, flow cytometry assay, rna quantitation assay is listed by: Eagle I nlx_156172 http://www.hms.harvard.edu/hddc/services/epithelial/ SCR_009712 2026-02-14 02:07:59 0

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