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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Pathema
 
Resource Report
Resource Website
1+ mentions
Pathema (RRID:SCR_010585) Pathema data analysis service, analysis service resource, database, production service resource, service resource, data or information resource Pathema is one of the eight Bioinformatics Resource Centers designed to serve as a core resource for the bio-defense and infectious disease research community. Pathema strives to support basic research and accelerate scientific progress for understanding, detecting, diagnosing and treating an established set of six target NIAID Category A-C pathogens: Category A priority pathogens; Bacillus anthracis and Clostridium botulinum, and Category B priority pathogens; Burkholderia mallei, Burkholderia pseudomallei, Clostridium perfringens and Entamoeba histolytica. Each target pathogen is represented in one of four distinct clade-specific Pathema web resources and underlying databases developed to target the specific data and analysis needs of each scientific community. All publicly available complete genome projects of phylogenetically related organisms are also represented, providing a comprehensive collection of organisms for comparative analyses. Pathema facilitates the scientific exploration of genomic and related data through its integration with web-based analysis tools, customized to obtain, display, and compute results relevant to ongoing pathogen research. Pathema serves the bio-defense and infectious disease research community by disseminating data resulting from pathogen genome sequencing projects and providing access to the results of inter-genomic comparisons for these organisms. The Pathema BRC contract ends in December 2009. At that time JCVI will cease maintenance of the Pathema web resource and data. The PATRIC team, located at the Virginia Bioinformatics Institute, created and maintains a consolidated BRC for all of the NIAID category A-C priority pathogenic bacteria. The EuPathDB team at the University of Pennsylvania will support all eukaryotic pathogens. Pathema transferred all data and software to PATRIC and EuPathDB for incorporation into their new Web-based bioinformatics resource. bacillus anthracis, clostridium botulinum, burkholderia mallei, burkholderia pseudomallei, clostridium perfringens, entamoeba histolytica, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: J. Craig Venter Institute
NIAID contract HHSN266200400038C PMID:19843611 biotools:pathema, nlx_45829 https://bio.tools/pathema SCR_010585 Pathema Genome Resource, Pathema Bioinformatics Resource Center 2026-02-16 09:47:47 6
ABySS
 
Resource Report
Resource Website
500+ mentions
ABySS (RRID:SCR_010709) ABySS software application, data processing software, sequence analysis software, data analysis software, software resource Software providing de novo, parallel, paired-end sequence assembler that is designed for short reads. ABySS 1.0 originally showed that assembling human genome using short 50 bp sequencing reads was possible by aggregating half terabyte of compute memory needed over several computers using standardized message passing system. ABySS 2.0 is Resource Efficient Assembly of Large Genomes using Bloom Filter. ABySS 2.0 departs from MPI and instead implements algorithms that employ Bloom filter, probabilistic data structure, to represent de Bruijn graph and reduce memory requirements. paired-end sequence assembler, short reads, assembling human genome, large genomes, bloom filter, is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
Genome Canada ;
Genome British Columbia ;
British Columbia Cancer Foundation ;
NHGRI R01HG007182
PMID:19251739
DOI:10.1101/068338
DOI:10.1101/gr.214346.116
Free, Available for download, Freely available biotools:abyss, OMICS_00006 https://github.com/bcgsc/abyss
https://sources.debian.org/src/abyss/
https://bio.tools/abyss
SCR_010709 ABySS 1.0, ABySS 2.0 2026-02-16 09:47:51 761
ArrayAnalysis.org
 
Resource Report
Resource Website
50+ mentions
ArrayAnalysis.org (RRID:SCR_010932) ArrayAnalysis.org data analysis service, analysis service resource, software resource, production service resource, service resource Tools for microarray quality control and pre-processing. r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:23620278 Acknowledgement requested OMICS_00742, biotools:arrayanalysis.org https://bio.tools/arrayanalysis.org SCR_010932 ArrayAnalysis 2026-02-16 09:47:59 72
nsSNPAnalyzer
 
Resource Report
Resource Website
10+ mentions
nsSNPAnalyzer (RRID:SCR_010780) nsSNPAnalyzer software application, data processing software, data analysis software, data analysis service, analysis service resource, software resource, production service resource, service resource A tool to predict whether a nonsynonymous single nucleotide polymorphism (nsSNP) has a phenotypic effect. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tennessee Health Science Center; Tennessee; USA
OMICS_00156, biotools:nssnpanalyzer https://bio.tools/nssnpanalyzer SCR_010780 nsSNPAnalyzer: predicting disease-associated nonsynonymous single nucleotide polymorphisms 2026-02-16 09:47:52 46
icy
 
Resource Report
Resource Website
100+ mentions
icy (RRID:SCR_010587) ICY software development tool, software application, data processing software, software development environment, image processing software, software repository, image analysis software, software resource, source code, service resource An open community platform for bioimage informatics providing the software resources to visualize, annotate and quantify bioimaging data. To bridge the gap between developers and users, it combines: a) an open-source image analysis software, offering a powerful and flexible environment for developers such as applied mathematicians to write algorithms fast and efficiently; b) a common set of tools to view and manipulate data, and a set of plugins to perform specific quantification or analysis on images; c) a community-based website centralizing all plugins and resources to facilitate their management and maximize their visibility towards users. Workspaces are virtual groups of plugins dedicated to a specific application or image processing domain. By downloading a workspace, ICY automatically installs all corresponding plugins. The workspaces are enabled, but the editing section is not ready yet. If you want to publish a plugin on this website, its code has to be GPL. Source code is available and provided in each application download. image analysis, microscopy, javascript, python, plugin, protocol, script, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Pasteur Institute
Centre National de la Recherche Scientifique ;
French National Research Agency ANR-10-INBS-04-06
PMID:22743774 Free, Open unspecified license, GNU General Public License, v3, The community can contribute to this resource biotools:icy, nlx_45928 https://bio.tools/icy SCR_010587 icy bioimage analysis 2026-02-16 09:47:54 320
Geneious
 
Resource Report
Resource Website
10000+ mentions
Geneious (RRID:SCR_010519) software application, data processing software, software toolkit, sequence analysis software, data analysis software, data management software, software resource Software package for sequence alignment, assembly and analysis. Integrated and extendable desktop software platform for organization and analysis of sequence data. Bioinformatics software platform packed with molecular biology and sequence analysis tools. Sequence alignment software, data management software, analysis software, Geneious Biologics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is parent organization of: Geneious Microsatellite Plugin
PMID:22543367 Restricted OMICS_00016, biotools:geneious http://nebc.nerc.ac.uk/news/geneiousonbl
https://bio.tools/geneious
SCR_010519 Geneious Prime, Geneious 11.0, Geneious 11.1.2, Geneious 8.1, Geneious Basic 2026-02-16 09:47:47 12252
Velvet
 
Resource Report
Resource Website
1000+ mentions
Velvet (RRID:SCR_010755) Velvet software application, data processing software, sequence analysis software, data analysis software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package as de novo genomic assembler for short read sequencing technologies using de Bruijn graphs. Takes in short read sequences, removes errors, then produces high quality unique contigs, retrieves repeated areas between contigs. Can leverage very short reads in combination with read pairs to produce useful assemblies. Operating system Unix/Linux., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. de novo, genomic, assembly, short, read, sequencing, de Bruijn, graph, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Velvet-SC
is related to: shovill
has parent organization: European Bioinformatics Institute
EMBL PMID:18349386
DOI:10.1101/gr.074492.107
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00038, biotools:velvet https://www.ebi.ac.uk/~zerbino/velvet/
https://bio.tools/velvet
https://sources.debian.org/src/velvet/
SCR_010755 2026-02-16 09:47:53 1036
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA software application, data processing software, sequence analysis software, data analysis software, image analysis software, software resource, alignment software Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/
https://bio.tools/bwa-sw
https://sources.debian.org/src/bwa/
SCR_010910 Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-02-16 09:47:54 2291
MetAMOS
 
Resource Report
Resource Website
10+ mentions
MetAMOS (RRID:SCR_011914) MetAMOS data processing software, software application, software resource, workflow software A modular and open source metagenomic assembly and analysis pipeline. microbiome, pipeline, microbiome, workflow software, metagenomic assembly, metagenomic assembly, bio.tools is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: bio.tools
is listed by: Debian
is hosted by: GitHub
Open source, Available for download OMICS_01426, biotools:metamos https://github.com/marbl/metAMOS
https://bio.tools/metamos
SCR_011914 2026-02-16 09:48:03 14
ECHO
 
Resource Report
Resource Website
100+ mentions
ECHO (RRID:SCR_011851) ECHO software application, data processing software, sequence analysis software, data analysis software, algorithm resource, software resource Error correction algorithm designed for short-reads from next-generation sequencing platforms such as Illumina''s Genome Analyzer II. error correction, rnaseq, rna sequence, short-read, next-generation sequencing, ngs, illumina, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21482625
DOI:10.1101/gr.111351.110
Free, Available for download biotools:echo, OMICS_01102 https://bio.tools/echo
https://sources.debian.org/src/uc-echo/
SCR_011851 ECHO: A reference-free short-read error correction algorithm 2026-02-16 09:48:00 310
JiffyNet
 
Resource Report
Resource Website
1+ mentions
JiffyNet (RRID:SCR_011954) software application, data analysis service, analysis service resource, software resource, simulation software, production service resource, service resource Web based instant protein network modeler for newly sequenced species. Web server designed to instantly construct genome scale protein networks using protein sequence data. Provides network visualization, analysis pages and solution for instant network modeling of newly sequenced species. protein network, protein, network, genome, sequence, pathway annotation, network visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Yonsei University; Seoul; South Korea
National Research Foundation of Korea ;
Next-Generation BioGreen 21 Program
PMID:23685435 Free, Freely available OMICS_01548, biotools:jiffynet https://bio.tools/jiffynet SCR_011954 2026-02-16 09:48:04 1
Pedigree-Draw
 
Resource Report
Resource Website
1+ mentions
Pedigree-Draw (RRID:SCR_008302) software application, software resource, commercial organization THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Software application for pedigree drawing (entry from Genetic Analysis Software) gene, genetic, genomic, macos, bio.tools is listed by: Genetic Analysis Software
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154520, OMICS_00213, SCR_010795 SCR_008302 PEDIGREE/DRAW 2026-02-16 09:47:09 1
COILS: Prediction of Coiled Coil Regions in Proteins
 
Resource Report
Resource Website
100+ mentions
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) data processing software, software application, software resource COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1126/science.252.5009.1162 biotools:ncoils, OMICS_07850, nif-0000-30263 https://bio.tools/ncoils
https://sources.debian.org/src/ncoils/
https://sources.debian.org/src/ncoils/ SCR_008440 COILS Server 2026-02-16 09:47:11 164
Subread
 
Resource Report
Resource Website
1000+ mentions
Subread (RRID:SCR_009803) data processing software, software application, software resource Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread. read alignment, DNA-seq reads mapping, RNA-seq reads mapping, mutation discovery, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Rsubread
has parent organization: University of Melbourne; Victoria; Australia
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support ;
Australian Government
PMID:23558742 Free, Freely available OMICS_01255, biotools:subread https://bio.tools/subread
https://sources.debian.org/src/subread/
SCR_009803 2026-02-16 09:47:31 1854
Assisted Model Building with Energy Refinement (AMBER)
 
Resource Report
Resource Website
1000+ mentions
Assisted Model Building with Energy Refinement (AMBER) (RRID:SCR_014230) AMBER software application, software resource, standalone software, simulation software Software package of molecular simulation programs. It is distributed into AmberTools15 and Amber14. AmberTools15 is a software package which can carry out complete molecular dynamics simulations with either explicit water or generalized Born solvent models. It is distributed in source code format and must be compiled in order to be used. Amber14 builds on AmberTools15 by adding the pmemd program, which provides better performance on multiple CPUs and dramatic speed improvements on GPUs compared to sander (molecular dynamics). GPU info, manuals, and tutorials are available on the website. molecular simulation, simulation software, software package, molecular dynamics, pmemed, sander, bio.tools is listed by: bio.tools
is listed by: Debian
Acknowledgement requested biotools:amber https://bio.tools/amber SCR_014230 Assisted Model Building with Energy Refinement 2026-02-16 09:48:33 4032
GSA-SNP
 
Resource Report
Resource Website
10+ mentions
GSA-SNP (RRID:SCR_013109) GSA-SNP data processing software, software application, software resource A tool for the gene-set (or pathway) analysis of a genome-wide association study result. It accepts a genome-wide list of SNPs and their association P-values. It summarizes the SNP P-values into nearby genes. The gene-by-gene summary results are then further summarized by gene-sets such as Gene Ontology, KEGG pathways, or user-created gene-sets. Various standardization and statistical tests can be performed and the resulting gene-sets that pass a significance level after multiple-testing correction are reported. The tool is written in Java and is available as a standalone version. clinical neuroinformatics, computational neuroscience, imaging genomics, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Soongsil University; Seoul; South Korea
PMID:20501604 GNU General Public License v2 nlx_155765, biotools:gsa-snp https://bio.tools/gsa-snp SCR_013109 2026-02-16 09:48:25 18
Trim Galore
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
Trim Galore (RRID:SCR_011847) Trim Galore! data processing software, software application, software resource Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data. Automate, quality, adapter, trimming, remove, biased, methylation, position, RRBS, reduced, representation, bisulfite, data, sequence, wrapper, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
works with: cutadapt
Free, Available for download, Freely available biotools:trim_galore, OMICS_01096, SCR_016946 https://github.com/FelixKrueger/TrimGalore
https://bio.tools/trim_galore
https://sources.debian.org/src/trim-galore/
SCR_011847 TrimGalore 2026-02-16 09:48:09 6255
docker4seq
 
Resource Report
Resource Website
1+ mentions
docker4seq (RRID:SCR_017006) data processing software, software application, software resource Software R package to execute next generation sequencing computing applications, e.g. reads mapping and counting, wrapped in docker containers. next, generation, sequencing, computing, application, read, mapping, count, docker, container, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: University of Turin;Turin;Italy
Free, Available for download, Freely available biotools:docker4seq https://kendomaniac.github.io/docker4seq/index.html
https://bio.tools/docker4seq
SCR_017006 2026-02-16 09:49:08 5
PALEOMIX
 
Resource Report
Resource Website
50+ mentions
PALEOMIX (RRID:SCR_015057) data processing software, software application, software resource, software toolkit THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software toolkit for the processing of ancient and modern HTS data. PALEOMIX also aids in metagenomic analysis of the extracts from the HTS processing. hts data, high-throughput sequencing, ancient dna, adna, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:24722405
DOI:10.1038/nprot.2014.063
THIS RESOURCE IS NO LONGER IN SERVICE biotools:paleomix, OMICS_03749 https://bio.tools/paleomix
https://sources.debian.org/src/paleomix/
SCR_015057 2026-02-16 09:48:41 65
NeLS
 
Resource Report
Resource Website
1+ mentions
NeLS (RRID:SCR_016301) NeLS data or information resource, organization portal, portal Web portal for the administration of Norwegian e-Infrastructure for Life Sciences. Enables Norwegian life scientists and their international collaborators to store, share, archive, and analyse their genomics scale data. NeLS is one of the packages of the ELIXIR.NO project. genomic, data, analyze, store, share, archive, electronic, infrastructure, administration, Norway, bio.tools is listed by: bio.tools
is listed by: Debian
Research Council of Norway Free, Freely available biotools:nels https://bio.tools/nels
https://github.com/elixir-no-nels/nels-core
https://bio.tools/nels
SCR_016301 Norwegian e-Infrastructure for Life Sciences 2026-02-16 09:49:00 3

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