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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://deweylab.biostat.wisc.edu/psginfer/
Software for inference of alternative splicing from RNA-Seq data with probabilistic splice graphs.
Proper citation: PSGInfer (RRID:SCR_000243) Copy
http://www.structbioinfor.org/cascleave2/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A novel tool developed using Java program for the high-throughput in silico identification of substrate cleavage sites for various caspases from the amino acid sequences of the substrates.
Proper citation: Cascleave (RRID:SCR_000197) Copy
http://www.bioconductor.org/packages/release/bioc/html/HEM.html
Software package that fits heterogeneous error models for analysis of microarray data
Proper citation: HEM (RRID:SCR_000194) Copy
http://molegro-virtual-docker.software.informer.com/
An integrated platform for predicting protein-ligand interactions, the visualization of new ideas and analyzing protein targets.
Proper citation: Molegro Virtual Docker (RRID:SCR_000190) Copy
A software-based network that provides efficient multicast and reduction communications for parallel and distributed tools and systems. Some key features of this resource include scalable data aggregation, multiple concurrent data channels and high-bandwidth communication.
Proper citation: MRNet (RRID:SCR_000225) Copy
http://www.bioinformatics.babraham.ac.uk/projects/fastq_screen/
Software that allows you to screen a library of sequences in FastQ format against a set of sequence databases so you can see if the composition of the library matches with what you expect.
Proper citation: FastQ Screen (RRID:SCR_000141) Copy
http://deweylab.biostat.wisc.edu/rsem/
Software package for quantifying gene and isoform abundances from single end or paired end RNA Seq data. Accurate transcript quantification from RNA Seq data with or without reference genome. Used for accurate quantification of gene and isoform expression from RNA-Seq data.
Proper citation: RSEM (RRID:SCR_000262) Copy
http://sourceforge.net/projects/ms-spectre/
Software that provides (Quantitiave) analysis of multiple ls-ms(ms) runs, using mzXML import of raw data coming from spectrometers.
Proper citation: MS-Spectre (RRID:SCR_000266) Copy
http://www.bioconductor.org/packages/release/bioc/html/GEOquery.html
Software that establishes a bridge between GEO and BioConductor.
Proper citation: GEOquery (RRID:SCR_000146) Copy
http://tomcat.esat.kuleuven.be/MACBETH/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 31, 2023. Web service for performing microarray classification. It aims at finding the best prediction among different classification methods by using randomizations of the benchmarking dataset.
Proper citation: M(at)CBETH (RRID:SCR_000265) Copy
http://sourceforge.net/projects/blastplot/
A PERL module that can quickly plot the BLAST results from short sequences (primers, probes, reads) against reference targets. This software generates PNG graphs for all of the reference sequences associated with a BLAST result set.
Proper citation: BLASTPLOT (RRID:SCR_000162) Copy
http://sourceforge.net/projects/gemsim/
A software package for generating realistic simulated next-generation genome sequencing reads with quality score values. The software is written in Python with a command-line user interface.
Proper citation: GemSIM (RRID:SCR_000167) Copy
http://sourceforge.net/projects/gmato/files/?source=navbar
A software tool used for simple sequence repeats (SSR) or microsatellite characterization. It also facilitates SSR marker design on a genomic scale, microsatellite mining at any length, and comprehensive statistical analysis for DNA sequences in any genome at any size. Analysis parameters are customizable.
Proper citation: GMATo (RRID:SCR_000165) Copy
http://cran.r-project.org/src/contrib/Archive/iFad/
An R software package implementing a bayesian sparse factor model for the joint analysis of paired datasets, the gene expression and drug sensitivity profiles, measured across the same panel of samples, e.g. cell lines.
Proper citation: iFad (RRID:SCR_000271) Copy
http://bioinfo.unl.edu/gramcluster.php
Software implementing a fast and accurate progressive clustering algorithm that relies on a grammar-based sequence distance and is particularly useful in clustering large datasets.
Proper citation: GramCluster (RRID:SCR_000272) Copy
http://cran.r-project.org/src/contrib/Archive/postgwas/
A comprehensive software toolkit for post-processing, visualization and advanced analysis of GWAS results.
Proper citation: Postgwas (RRID:SCR_000156) Copy
http://bioconductor.org/packages/release/bioc/html/DESeq.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression.
Proper citation: DESeq (RRID:SCR_000154) Copy
https://github.com/davidliwei/RNASeqReadSimulator
A software tool to generate simulated single-end or paired-end RNA-Seq reads. # It allows users to randomly assign expression levels of transcripts and generate simulated single-end or paired-end RNA-Seq reads. # It is able to generate RNA-Seq reads that have a specified positional bias profile. # It is able to simulate random read errors from sequencing platforms. # The simulator consists of a few simple Python scripts. All scripts are command line driven, allowing users to invoke and design more functions.
Proper citation: RNASeqReadSimulator (RRID:SCR_000270) Copy
http://www.bioconductor.org/packages/release/bioc/html/MIMOSA.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software for modeling count data using Dirichlet-multinomial and beta-binomial mixtures with applications to single-cell assays.
Proper citation: MIMOSA (RRID:SCR_000184) Copy
https://www.schrodinger.com/glide
Software package which approximates a complete search of the conformational, orientational, and positional space of the ligand in a given receptor. Used in drug development for predicting protein ligand binding modes and ranking ligands via high throughput virtual screening.
Proper citation: Glide (RRID:SCR_000187) Copy
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