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https://www.dartmouth-hitchcock.org/pathology/research#ibr

Institutional resource collaboratively run by Office of Research Operations and Department of Pathology and Laboratory Medicine that provides services in support of Dartmouth Research Communities and in alignment with Institutional Review Board approved protocols including Clinical Trials. Provides collection, processing, storage, and distribution of annotated human bio-specimens to clinicians and other investigators in support of clinical trials, industry sponsored projects, and scientific investigations.

Proper citation: Dartmouth Health Hitchcock Medical Center Biorepository Core Facility (RRID:SCR_023735) Copy   

•   Source: SciCrunch Registry

https://bic.nd.edu/

Offers instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for isolation and purification of macromolecules for subsequent detailed biophysical analysis.

Proper citation: University of Notre Dame ND Biophysics Instrumentation Core Facility (RRID:SCR_023867) Copy   

•   Source: SciCrunch Registry

https://health.ucdavis.edu/cancer/research/sharedresources/cmp.html

Provides services to support the development and implementation of clinical trials at UC Davis Comprehensive Cancer Center. Oversees high quality collection, processing, and analysis of clinical specimens,typically but not exclusively blood specimens, for pharmacokinetic and pharmacodynamics studies. Conducts preclinical modeling of novel anti cancer agents to test hypotheses and develop scientific rationale required for translation of laboratory concepts into clinical trials, including assessment of DM/PK/PD properties.

Proper citation: University of California Davis Health Molecular Pharmacology Shared Resource Core Facility (RRID:SCR_023588) Copy   

•   Source: SciCrunch Registry

https://www.research.colostate.edu/epf/

Core provides pathologic services ranging from animal model troubleshooting, and tissue fixation to stain slide prep and immunohistochemistry. Offers expertise in slide interpretations and quantitative histopathology in anatomic and clinical pathology. Offers molecular pathology services via Nanostring nCounter equipment.

Proper citation: Colorado State University Experimental Pathology Core Facility (RRID:SCR_023562) Copy   

•   Source: SciCrunch Registry

https://www.feinberg.northwestern.edu/sites/transplant/research/research-cores/immune-core.html

Core of Comprehensive Transplant Center provides translational mechanistic studies in human solid organ and cellular transplantations. Provides assistance with human immune monitoring needs for translational and clinical transplantation research projects.Offers immune monitoring services for translational mechanistic studies.

Proper citation: Northwestern University Immune Monitoring Core Facility (RRID:SCR_023561) Copy   

•   Source: SciCrunch Registry

https://ibt.tamu.edu/centers/translational-cancer-research/stephan-lab/mlots/index.html

Supports lead optimization programs and has established roster of medium throughput microphysiologic screening platforms including tissue- and tumor-on-a-chip platforms, organoid, and spheroid culture systems that will be used to evaluate efficacy and toxicity of new lead compounds and drug combinations.Provides resources to identify toxic liabilities in lead series molecules before entering pre-clinical or clinical testing. MLOTS can evaluate NME for cardiovascular, neuro, or liver toxicity relative to reference standards using in vitro screening platforms. Facility will potentially enhance the effectiveness of CPRITs drug discovery programs.

Proper citation: Texas A and M University Health Institute of Biosciences and Technology Microphysiological Lead Optimization and Toxicity Screening Core Facility (RRID:SCR_023717) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/cancer/research/shared-resources/biostatistics_research_informatics.html

Core provides statistical support to SCI members by engages them on their data related needs. Specifically, BSR members assist researchers at each stage of study’s lifecycle, including project design, mid study evaluation and interpretation and reporting of results. In addition, BSR members mentor SCI investigators in research methods. BSR assists with development and review of proposed studies and planning of research related data management systems.

Proper citation: Stanford University School of Medicine Cancer Institute Biostatistics Shared Resource Core Facility (RRID:SCR_023696) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/spectrum/ctsa-cores-and-programs/research-methods-core/berd.html

Core provides CTR investigators with support for study design development, data curation and management, and analytic strategies. Provides infrastructure through Data Studio; Clinical Office Hours; Data Science Navigation.

Proper citation: Stanford Spectrum Biostatistics Epidemiology and Research Design Core Facility (RRID:SCR_023695) Copy   

•   Source: SciCrunch Registry

http://researchservices.pitt.edu/facilities/machine-shop

Core specializes in mechanical design, fabrication, and repair of research equipment and instrumentation.

Proper citation: University of Pittsburgh Dietrich School Machine Shop Core Facility (RRID:SCR_023720) Copy   

•   Source: SciCrunch Registry

https://www.uniklinik-freiburg.de/medizin1/forschung/lighthouse-core-facility.html

Core specializes in areas of flow cytometry and cell sorting; light microscopy including confocal, widefield fluorescence, high content screening, lightsheet, slide scanning, highly multiplexed microscopy; and digital PCR / QPCR. It is located at University of Freiburg Medical Center and hosts institutions including Dept. of Medicine I, Center for Chronic Immunodeficiency (CCI), CCCF / DKTK, and Medical Faculty of University of Freiburg.

Proper citation: University of Freiburg Medical Center Lighthouse Core Facility (RRID:SCR_023785) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/fcc/

Core provides sorting, sample analysis and analyzer training.Provides quantitative flow cytometric analyses on samples including blood, bone marrow, spleen, serum, plasma, solid tissues, cell extracts to support both clinical and basic research efforts. These analyses will provide insight on cell function and precursors whose abundance can be monitored as biomarkers to predict and follow progression of a wide range of diseases, such as H1N1, yellow fever, dengue, neurodegenerative diseases, stem cell studies.Provides consultations, expert training, and support for all systems and provides access to equipment.

Proper citation: Emory University School of Medicine Flow Cytometry Core Facility (RRID:SCR_023536) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/tmf/index.html

Provides equipment and expertise for generating and characterizing genetically altered mouse models. Please contact us so that we can discuss your experimental needs.

Proper citation: Emory University Mouse Transgenic and Gene Targeting Core Facility (RRID:SCR_023535) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/ici/index.html

Provides light microscopy. Offers expertise in imaging for experimental needs.

Proper citation: Emory University Emory Integrated Cellular Imaging Core Facility (RRID:SCR_023534) Copy   

•   Source: SciCrunch Registry

https://winshipcancer.emory.edu/research/shared-resources/emory-cellular-immunotherapy-core.html

Clinical cell manufacturing facility that prepares cell and immunotherapy products under current Good Manufacturing Practices for development of investigational new drugs and diagnostics methods.Provides GMP compliant cell manufacturing and/or consultation for translational of Emory based or external research collaborations into early phase clinical trials.

Proper citation: Emory University Emory Cellular and Immunotherapy Core Facility (RRID:SCR_023533) Copy   

•   Source: SciCrunch Registry

https://www.cch.uleth.ca

Provides comprehensive solution characterization of macromolecules or macromolecular interactions and assemblies. This includes description of stoichiometry, size composition, cargo loading.Core is equipped with analytical ultracentrifuges featuring multi-wavelength UV-visible detection, as well as Rayleigh interference optics and fluorescence emission detection for fluorescent tags with 488 nm excitation.

Proper citation: University of Lethbridge Canadian Center for Hydrodynamics Core Facility (RRID:SCR_023791) Copy   

•   Source: SciCrunch Registry

https://med.miami.edu/research/cores/biomarker-and-immunoassay-laboratory

Provides biomarker testing for human clinilcal research studies across multiple disciplines.Provides expertise with chemistry, special chemistry, radioimmunoassay, nephelometric and ELISA and multiplexing assay methods utilizing automated and manual procedures. Laboratory has Clinical Laboratory Improvement Act certification and follows guidelines established by CLIA for quality control and proficiency testing to ensure results. Core coordinates proper pre-analytical sample collection and processing procedures with project leaders; performs biochemical assays on samples submitted to the laboratory by investigators in manner that assures strict quality control both within and between assay runs; reports results to project staff in timely fashion; makes available expertise and technical assistance for establishing and validating new methodologies to support University of Miami investigators.

Proper citation: University of Miami Miller School of Medicine Biomarkers and Immunoassay Laboratory Core Facility (RRID:SCR_023705) Copy   

•   Source: SciCrunch Registry

https://nyumc.ilab.agilent.com/service_center/show_external/4296?name=experimental-pathology-research-laboratory

Core provides services, access to instruments, and training to facilitate production of animal tissue samples for morphological and molecular analyses. Supports multiplex immunofluorescence staining, RNA in situ hybridization (ISH), and imaging analysis. Services include tissue preparation, processing, and sectioning, as well as histochemistry and immunohistochemistry of fresh, frozen, and fixed animal tissues, can optimize and validate commercial or proprietary antibodies for chromogenic or fluorescence-based immunohistochemistry including seven-color multiplexing.Provides access to database listing antibodies that have been tested in lab to date and are currently in stock.Offers basic imaging resources and digital whole-slide scanning of stained tissue sections, which allows researchers to view their slides online at their convenience.Researchers can also rent our self-service instruments. These include embedding station, microtome, cryostat, and vibratome. Provides access to brightfield and fluorescence upright and dissecting microscopes,laser capture microdissection scope, and high-throughput multispectral imaging system.To reserve time on instrument, faculty, staff, and investigators must be registered in iLab.

Proper citation: New York University School of Medicine Langone Health Experimental Pathology Research Laboratory Core Facility (RRID:SCR_017928) Copy   

•   Source: SciCrunch Registry

https://ki.mit.edu/sbc/bioinformatics

Core provides support, assistance and training in wide range of bioinformatics topics. Maintains high-performance computing resource offering many bioinformatics applications, substantial processing power and secure storage. Provides support for desktop computing and poster printing. Services include Data Analysis, Software Support (access to proprietary bioinformatics resources Ingenuity Pathway Analysis and GeneGO MetaCore, Training sessions covering various bioinformatics topics, Linux compute cluster, data storage.

Proper citation: Massachusetts Institute of Technology Koch Institute Bioinformatics and Computing Core Facility (RRID:SCR_017894) Copy   

•   Source: SciCrunch Registry

https://coreimmunology.ucsf.edu/services

Provides immunology assays, expert consultation, and education to UCSF and global research community. CIL specializes in developing immunology research tools, and initiating and stimulating innovative research projects to address emerging questions in immunologic diseases including HIV pathogenesis.Services include:Isolation of PBMC for staining, cell sorting, or viable cryopreservation;Isolation of mucosal mononuclear cells (MMC) from mucosal tissue biopsies;Immunomagnetic bead isolation of untouched cell populations for functional studies;Immunophenotyping of whole blood, PBMC, MMC and cerebrospinal fluid for: NK, B and T cells percentages, and their subsets, including maturation, trafficking, senescence, activation, in vivo proliferation and chemokine receptor expression;Flow cytometric functional assays, including NK cell function, antigen-specific CD4+ and CD8+ T cell cytokine expression, degranulation and proliferation;Evaluation of T cell signaling by phosflow using monoclonal antibodies specific for phosphorylated protein;Training and Support;Flow Cytometry Training Course;Three-hour lecture and lab course designed to cover basics of flow cytometry including:Fluorescence emission and detection,Fluidics,Operation,Panel design,Controls.

Proper citation: University of California at San Francisco Immunology Lab Core Facility (RRID:SCR_017906) Copy   

•   Source: SciCrunch Registry

https://flow.ucsf.edu/

Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as isolation of cells based on those markers. Advanced cell sorting and cytometric analyses by Flow or Mass Cytometry are provided.

Proper citation: University of California San Francisco Parnassus Flow Cytometry Core Facility (RRID:SCR_018206) Copy   

•   Source: SciCrunch Registry