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https://www.leica-microsystems.com/products/light-microscopes/p/leica-lmd7000/
Specimen collection by gravity contact-free and contamination-free. Laser Microdissection (LMD) makes it possible to distinguish between relevant and non-relevant cells or tissues. It enables the researcher to obtain homogeneous, ultra-pure samples from heterogeneous starting material. Researcher can selectively and routinely analyze regions of interest down to single cells from all kinds of tissues, even living cells from cell culture, to obtain results that are relevant, reproducible, and specific.
Proper citation: Leica LMD7000 Laser Microdissection System (RRID:SCR_020232) Copy
https://www.leicabiosystems.com/histology-equipment/microtomes/products/leica-rm2255/
Leica RM2255 rotary microtome is designed for fully motorized sectioning of both paraffin- and the Leica RM2255 in routine and in histology. Its two-in-one design concept, which allows motorized and manual sectioning, provides reproducible high-quality sections.
Proper citation: Leica RM2255 Automated Microtome (RRID:SCR_020229) Copy
Leica EG1150 H is a heated, paraffin dispensing module with 3-liter capacity and a heated work surface with storage areas for both cassettes and molds. All functions of the EG1150 H are controlled via an easy-to-read LED display, including the temperature settings for left and right hand warming trays, paraffin reservoir, and working surface.
Proper citation: Leica EG1150H Heated Paraffin Embedding Module (RRID:SCR_020227) Copy
Vibrating blade microtome for sectioning by Leica Biosystems used in neurophysiology, neuropathology, experimental pathology, botany. Fully automated Leica VT1200 S vibrating blade microtome for cutting fresh and fixed tissue in Neuroscience. To achieve sections of the highest quality that retain viable cells on the section surface, the vertical deflection of the blade can be measured by Leica's Vibrocheck measurement device and minimised with the blade holder. The instrument was designed in collaboration with Prof. Dr. Peter Jonas and his group at the Physiology Department, Freiburg Germany.
Proper citation: Leica VT1200S vibrating microtome (RRID:SCR_020243) Copy
https://www.thermofisher.com/order/catalog/product/A28137#/A28137
System designed for users who need easy-to-use real-time PCR system that doesn't compromise performance and quality. Using OptiFlex technology (featuring 4 coupled channels and white LED) and featuring three independent Veriflex temperature zones, the QuantStudio 3 system enables improved data accuracy and sensitivity for broad range of genomic applications.
Proper citation: Life Technologies QuantStudio 3 Real Time PCR System (RRID:SCR_020238) Copy
https://www.leica-microsystems.com/products/confocal-microscopes/p/leica-tcs-sp5/
Leica TCS SP5 is a broadband confocal microscope that provides the full range of scan speeds at the a high resolution. With its SP detection (five channels simultaneously) and optional AOBS (Acousto Optical Bream Splitter), the Leica TCS SP5 delivers bright, noise-free images with minimal photo damage at high speed. The system is also the platform for the new Leica DM6000 CFS (Confocal Fixed Stage) for physiological and electrophysiological experiments and for the new super resolution Leica TCS STED confocal microscope.
Proper citation: Leica TCS SP5 Broadband Confocal Laser Scanning Microscope (RRID:SCR_020233) Copy
https://www.marshallscientific.com/v/vspfiles/files/manuals/User%20Manual%20-%20Gemini%20XS.pdf
SPECTRAmax GEMINI XS Dual-Scanning Microplate Spectrofluorometer can perform a variety of fluorescent applications as well as some time-resolved fluorescent and luminescent assays. The extreme flexibility and high sensitivity of the SPECTRAmax GEMINI XS make it appropriate for applications within the fields of biochemistry, cell biology, immunology, molecular biology, and microbiology. The SPECTRAmax GEMINI XS uses two holographic diffraction grating monochromators which allow for individual optimization of wavelengths for both excitation and emission. The dual-scanning capability can also be used to determine excitation and emission settings for new fluorescent probes. Mirrored optics focus the light into the sample volume and cutoff filters are used to reduce stray light and minimize background interference. The light source is a highpowered Xenon flashlamp; additional flexibility is provided by allowing a variable number of lamp flashes per read. Microplates having 6, 12, 24, 48, 96, and 384 wells can be used in the SPECTRAmax GEMINI XS. Fluorescent detection is achieved from the top, through the entire depth of sample in the microplate well. Detection of species collected on membrane plates is also possible. Two plate carrier adapters are provided with the instrument. The blue adapter is required for optimum performance with standard 96- and 384-well format microplates. The red adapter has been optimized for use with Cliniplate 384 microplates.
Proper citation: Molecular Devices SpectraMax Gemini XS Microplate Spectrofluorometer (RRID:SCR_020296) Copy
https://www.microscopeinternational.com/product/nikon-smz-1-microscope-on-plain-stand/
Nikon SMZ-1 and SMZ-1B zoom stereo microscopes offer legendary Nikon stereo performance. Developed to fit a variety of applications and OEM needs, these advanced-design stereo microscopes have the features and image quality you expect from Nikon. High-performance optics and a 6V/10W halogen illuminator deliver images with excellent contrast, resolution, and brightness. The SMZ-1 and SMZ-1B are human-engineered to allow long periods of operation without fatigue. Mechanical design is yet rugged for daily trouble-free operation in industrial, laboratory, and classroom environments. All controls are easy to use. Nikon's versatile modular approach allows the SMZ-1/1B to be easily adapted to various configurations such as stand, arm, or table mounting. Similarly, the illuminator can be fixed to the instrument stand, placed in a diascopic base, or attached externally for oblique lighting. The SMZ-1/1B use a Nikon-designed twin-lens objective system inclined at 12o. Only the center of the lenses is used to provide the sharpest three-dimensional image and enable the operator to work more accurately and efficiently for prolonged periods without eye strain.
Proper citation: Nikon SMZ-1 Microscope (RRID:SCR_020328) Copy
http://www.labwrench.com/?equipment.view/equipmentNo/9411/Nikon/Eclipse-55i/
Versatile Eclipse 55i clinical microscope offers optical capabilities, unsurpassed ergonomic features and is optimized for digital imaging. Its white LED illumination system provides a homogenous and bright distribution of illumination across the field for optimal viewing and digital imaging, resulting in spectacular, vivid, true-to-life colors. ergonomic features, like the stay-in-position stage handle and tilting/telescoping ergonomic eyepiece tube ensure best viewing posture, enabling long hours of observations to be carried out in comfort.
Proper citation: Nikon 55i Upright Microscope (RRID:SCR_020321) Copy
https://www.labx.com/product/olympus-bh2
Goal of the BH2 was superior optics and customizability, and it soon became very well known for both. Standard equipment on this microscope included 10x widefield high eyepoint eyepieces having a field number of 20, precentered halogen lamps, aspherical collector lenses, and fully enclosed light paths designed to exclude dirt and dust. Auxiliary components for the microscope included photoeyepieces, an automatic exposure photomicrography system, and a wide range of objectives covering the entire range of correction and magnification. In addition, both mechanical and circular stages were offered as were binocular and trinocular observation tubes. Contrast enhancing equipment included phase contrast, differential interference contrast, darkfield, fluorescence, and polarized light.
Proper citation: Olympus BH-2 Fluorescence Microscope (RRID:SCR_020338) Copy
https://www.marshallscientific.com/Nikon-TMS-Inverted-Phase-Contrast-Microscope-p/ni-tms.htm
Nikon TMS Inverted Phase Contrast Microscope produces high quality images for tissue culture labs, readily meeting biological and metallurgical research needs. This Nikon microscope offers operation with an easy-to-maintain inverted microscope frame. This inverted phase microscope is configured with 4x achromat, 10x Ph1, and 20x Ph2 objectives with critical halogen illumination. The TMS can accommodate a variety of Nikon CF objectives on its revolving triple nosepiece, along with multiple other accessories, such as stage adapters and extenders, sliders and rings, and extra long working condensers. The 4x achromat objective provides a lower magnification for a wider field of view, primarily best for when needing to view a large portion of a slide for study. The 10x Ph1 provides phase contrast low-power magnification, while the 20x Ph2 provides medium-power magnification with a larger aperture.
Proper citation: Nikon TMS Inverted Phase Contrast Microscope (RRID:SCR_020332) Copy
https://www.barcodesinc.com/motorola/ds4208.htm#
General purpose imager that delivers the speed typical of laser scanners on both 1D and 2D barcodes, accommodating 2D barcodes without sacrificing performance. Users never need to take time to align the barcode with the scanner or pause between scans. Since the DS4208 can scan barcodes printed on paper labels or on mobile phone displays, users can drive revenue by attracting the millions of customers who are using their cell phones to better manage their lives. Retailers can accommodate customers who download mobile coupons, mobile loyalty cards and more. Quick service restaurants can accept mobile coupons at the register. Hotels can allow guests to use electronic loyalty cards stored on their cell phones, eliminating the need to carry physical cards. And since theaters, theme parks and stadiums can scan mobile tickets as easily as a paper ticket, they can offer customers an added convenience: paperless ticketing.
Proper citation: Motorola DS4208 Barcode Scanner (RRID:SCR_020302) Copy
Microplate Reader delivers single mode reader performance and can be equipped to read volumes as low as 2uL in one multimode reader package. The dual monochromator optics allow the widest range of applications to be utilized for bioresearch and drug discovery applications, all without the need to change filters. For fluorescence intensity, time resolved fluorescence, and fluorescence polarization assays, the SpectraMax M5 Microplate Reader optical design provides the highest level of flexibility. Users can select from top or bottom read modes for improved sensitivity for solution and cell-based assays. Assays can be better optimized by scanning across a range of wavelengths in increments as small as 1 nm. Up to 4 wavelength pairs can be read in one protocol for endpoint and kinetic measurements, allowing for fast setup of FRET and TR-FRET assays. For luminescence, the SpectraMax M5 Microplate Reader utilizes a dedicated luminescence photomultiplier tube (PMT), providing the user the maximum signal and lowest background possible for glow luminescence reporter gene assays. The SpectraMax M5 utilizes a single monochromator design for UV/VIS Absorbance, allowing the user to maximize sensitivity and tunability, and also uses patented PathCheck Pathlength Measurement Technology: the only temperature independent pathlength correction for microplates. The M5 can read volumes down to 2uL with the uMax Low Volume Plate.
Proper citation: Molecular Devices SpectraMax M5 Multimode Plate Reader (RRID:SCR_020300) Copy
https://www.thermofisher.com/order/catalog/product/ND-2000
Full-spectrum, UV-Vis spectrophotometer used to quantify and assess purity of DNA, RNA, Protein and more.NanoDrop 2000c combines micro-volume pedestal technology and cuvette capability in single instrument.Provides expanded measurement options for all types of samples.Provides broader concentration range for measuring very low concentrations and very high concentrations. Cuvette capability allows for kinetics (time or time/temperature studies) and cell culture (OD 600) measurements.
Proper citation: Thermo Scientific NanoDrop 2000c Spectrophotometer (RRID:SCR_020309) Copy
Basic confocal system consisting of a separate scan head, standard 5 PMT detectors, control module, and laser module. The A1 has a new multi-detector unit with 2 GaAsp PMT detectors to give brighter signals, enhanced signal-to-noise, and allow less phototoxicity.Fully automated A1 offers standard paired galvanometers with high resolution scanning at up to 4096 x 4096 pixels.
Proper citation: Nikon A1 Confocal Laser Scanning Microscope System (RRID:SCR_020318) Copy
PerkinElmer UltraVIEW system (PerkinElmer Life Sciences Inc., MA, USA) is a Yokogawa (Yokogawa Corp. Japan) Nipkow Spinning Disk Confocal System. It uses a spinning disk with multiple pinholes to achieve confocality (e.g. the rejection of out-of-focus light). Emission light from the sample passes through the pinholes to generate a confocal image of the sample that can be detected with an EMCCD (Electron Multiplification Charge-Coupled Device) camera. Spinning disk confocal systems have 2 main advantages over conventional Laser Scanning Confocal Microscopes (LSCM): Higher imaging speed: up to 360frames/sec compared to 0.5-1 frames per second in a LSC and Lower photo-toxicity: around 5 times less than a LSCM, probably due to the fact that the system splits the laser light into thousands of minibeams.
Proper citation: Perkin Elmer UltraView ERS (RRID:SCR_020405) Copy
https://www.gyrosproteintechnologies.com/peptide-synthesizers
Protein Technologies peptide synthesizers are designed to cover synthesis scales from 0.005 to 200 mmol.
Proper citation: Protein Technologies Tribute (RRID:SCR_020408) Copy
https://www.proteinsimple.com/peggy_sue.html
Peggy Sue lets you separate and analyze proteins by size or charge from 2-440 kDa either by immunoassay or total protein.
Proper citation: Protein PeggySue Protein Analyzer (RRID:SCR_020406) Copy
Barocycler uses the Pressure Cycling Technology (PCT) platform based on repeated cycles of hydrostatic pressure between ambient (14.7 psi) and ultra-high levels (up to 45,000 psi). These rapid changes in pressure are used to control biomolecular interactions for applications such as accelerated proteolytic digestion and improved extraction of cellular components, including proteins and lipids. The PCT platform allows for a high degree of safety, speed, reproducibility, and in modern sample preparation protocols. Advantages of the PCT technology include:
Proper citation: Pressure BioSciences NEP2320 Barocycler (RRID:SCR_020415) Copy
For automated purification of nucleic acids from up to 14 human, forensic, or molecular diagnostics samples High quality genomic DNA and RNA from range of sample materials Viral RNA DNA and bacterial DNA from biomedical samples Throughput of up to 14 samples per run Effortless data management with full traceability UV lamp to help minimize contamination risk The EZ1 Advanced XL performs automated nucleic acid purification for wide range of sample types relevant for molecular diagnostics, human identity testing, forensics, biomedical research, and gene expression analysis.
Proper citation: QIAgen EZ1 Advanced XL (RRID:SCR_020416) Copy
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