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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
RepARK
 
Resource Report
Resource Website
1+ mentions
RepARK (RRID:SCR_002333) software resource Software using a de novo repeat assembly method which avoids potential biases by using abundant k-mers of next-generation sequencing (NGS) whole genome sequencing (WGS) reads without requiring a reference genome. standalone software is listed by: OMICtools PMID:24634442 OMICS_03446 SCR_002333 Repetitive motif detection by Assembly of Repetitive K-mers 2026-02-14 02:00:23 7
MBASED
 
Resource Report
Resource Website
10+ mentions
MBASED (RRID:SCR_002584) software resource Software package containing functions for allele-specific gene expression (ASE) analysis using meta-analysis based allele-specific expression detection. software package, unix/linux, mac os x, windows, r, gene expression, sequencing, transcription is listed by: OMICtools
has parent organization: Bioconductor
PMID:25315065 Free, Available for download, Freely available OMICS_05502 http://www.bioconductor.org/packages/release/bioc/html/MBASED.html SCR_002584 Meta-analysis Based Allele-Specific Expression Detection, MBASED - Package containing functions for ASE analysis using Meta-analysis Based Allele-Specific Expression Detection 2026-02-14 02:00:17 17
pymzML
 
Resource Report
Resource Website
10+ mentions
pymzML (RRID:SCR_002500) software resource Python module to parse mzML data in Python based on cElementTree. It is an extension to Python that offers (i) an easy access to mass spectrometry (MS) data that allows the rapid development of tools, (ii) a very fast parser for mzML data and (iii) a set of functions to compare or handle spectra., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: mzML
has parent organization: University of Munster; North Rhine-Westphalia; Germany
PMID:22302572 Free, Available for download, Freely available biotools:pymzml, OMICS_03355 https://bio.tools/pymzml SCR_002500 2026-02-14 02:00:17 18
PeptideShaker
 
Resource Report
Resource Website
100+ mentions
PeptideShaker (RRID:SCR_002520) software resource Software providing a search engine independent platform for visualization of peptide and protein identification results from multiple search engines, currently supporting X!Tandem, MS-GF+, MS Amanda, OMSSA, MyriMatch, Comet, Tide, Mascot and mzIdentML. By combining the results from multiple search engines, while re-calculating PTM localization scores and redoing the protein inference, PeptideShaker attempts to give you the best possible understanding of your proteomics data. standalone software, proteomics, mass spectrometry, java, search engine, omssa, xtandem, mascot, ms-gf, msamanda, myrimatch, comet, tide is listed by: OMICtools
is related to: MS Amanda
has parent organization: Google Code
PMID:34709836 Free, Available for download, Freely available OMICS_03347 http://peptide-shaker.googlecode.com SCR_002520 2026-02-14 02:00:26 160
PennCNV
 
Resource Report
Resource Website
100+ mentions
PennCNV (RRID:SCR_002518) PennCNV software resource A free software tool for Copy Number Variation (CNV) detection from SNP genotyping arrays. Currently it can handle signal intensity data from Illumina and Affymetrix arrays. With appropriate preparation of file format, it can also handle other types of SNP arrays and oligonucleotide arrays. PennCNV implements a hidden Markov model (HMM) that integrates multiple sources of information to infer CNV calls for individual genotyped samples. It differs form segmentation-based algorithm in that it considered SNP allelic ratio distribution as well as other factors, in addition to signal intensity alone. In addition, PennCNV can optionally utilize family information to generate family-based CNV calls by several different algorithms. Furthermore, PennCNV can generate CNV calls given a specific set of candidate CNV regions, through a validation-calling algorithm. imaging genomics, copy number variation, snp, genotyping array, array, oligonucleotide, hidden markov model, genotype, genome is listed by: OMICtools
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: VegaMC
is related to: OpenBioinformatics.org
has parent organization: University of Pennsylvania; Philadelphia; USA
NIMH MH604687 PMID:17921354 Free OMICS_00729, nlx_155921 http://www.openbioinformatics.org/penncnv/
http://www.neurogenome.org/cnv/penncnv SCR_002518 PennCNV: copy number variation detection 2026-02-14 02:00:26 349
BINOCh
 
Resource Report
Resource Website
1+ mentions
BINOCh (RRID:SCR_002778) BINOCh software resource Software that infers the identity of transcription factors used to regulate cell response to stimulus or determine a program of differentiation. It uses genome wide information on enhancer proximal nucleosome occupancy, acquired using ChIP-seq targeting enhancer related histone modifications., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. proximal nucleosome occupancy data, transcription factor determination, differentiation is listed by: OMICtools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Harvard University; Cambridge; United States
PMID:21551136 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00500 SCR_002778 Binding Inference from Nucleosome Occupancy Changes (BINOCh), BINOCh - Binding Inference from Nucleosome Occupancy Changes, Binding Inference from Nucleosome Occupancy Changes 2026-02-14 02:00:26 3
sapFinder
 
Resource Report
Resource Website
sapFinder (RRID:SCR_002685) software resource An R software package, for detection of the variant peptides based on tandem mass spectrometry (MS/MS)-based proteomics data. It automates (1) variation-associated database construction, (2) database searching, (3) post-processing, (4) HTML-based report generation in shotgun proteomics. standalone software, r, mass spectrometry, proteomics, rna-seq, report writing, snp, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:25053745 Free, Available for download, Freely available biotools:sapfinder, OMICS_05285 https://bio.tools/sapfinder SCR_002685 sapFinder - A package for variant peptides detection and visualization in shotgun proteomics. 2026-02-14 02:00:26 0
leeHom
 
Resource Report
Resource Website
50+ mentions
leeHom (RRID:SCR_002710) software resource Software program for the Bayesian reconstruction of ancient DNA fragments. The algorithm removes the adaptors and reconstructs the original DNA sequences using a Bayesian maximum a posteriori probability approach. standalone software, illumina, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25100869 Free, Available for download, Freely available biotools:leehom, OMICS_05254 https://bio.tools/leehom SCR_002710 2026-02-14 02:00:26 53
Pathview
 
Resource Report
Resource Website
500+ mentions
Pathview (RRID:SCR_002732) software resource A tool set for pathway-based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. All users need is to supply their data and specify the target pathway. Pathview automatically downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, Pathview also seamlessly integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. software package, r, differential expression, gene expression, gene set enrichment, genetics, graph, network, metabolomics, microarray, pathway, proteomics, rna-seq, sequencing, systems biology, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23740750 Free, Freely available, Available for download biotools:pathview, OMICS_05212 http://pathview.r-forge.r-project.org/
https://bio.tools/pathview
SCR_002732 path view 2026-02-14 02:00:30 520
GLProbs
 
Resource Report
Resource Website
1+ mentions
GLProbs (RRID:SCR_002739) software resource Software implementing a simple and effective approach to improve the accuracy of multiple sequence alignment. standalone software is listed by: OMICtools
has parent organization: SourceForge
PMID:26357079 Free, Freely available, Available for download OMICS_03732 SCR_002739 2026-02-14 02:00:19 1
rBiopaxParser
 
Resource Report
Resource Website
1+ mentions
rBiopaxParser (RRID:SCR_002744) software resource A software package that provides a comprehensive set of functions for parsing, viewing and modifying BioPAX pathway data within R. At the moment BioPAX level 2 and level 3 are supported. software package, mac os x, unix/linux, windows, data representation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23274212 Free, Freely available, Available for download biotools:rbiopaxparser, OMICS_05211 https://github.com/frankkramer/rBiopaxParser
https://bio.tools/rbiopaxparser
SCR_002744 rBiopaxParser - Parses BioPax files and represents them in R 2026-02-14 02:00:19 4
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-02-14 02:00:50 1
AGORA
 
Resource Report
Resource Website
50+ mentions
AGORA (RRID:SCR_005070) AGORA software resource An algorithm to use optical map information directly within the de Bruijn graph framework to help produce an accurate assembly of a genome that is consistent with the optical map information provided. AGORA takes as input two data structures: OpMap ? an ordered list of fragment sizes representing the optical map; and Edges ? a list of de Bruijn graph edges with their corresponding sequences. genome assembly, genome, reconstruction is listed by: OMICtools PMID:22856673 OMICS_00039 SCR_005070 Assembly Guided by Optical Restriction Alignment 2026-02-14 02:01:03 99
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-02-14 02:00:48 89
MapAl
 
Resource Report
Resource Website
1+ mentions
MapAl (RRID:SCR_004938) MapAl software resource A software tool for RNA-Seq expression profiling that builds on the established programs Bowtie and Cufflinks. Allowing an incorporation of ''gene models'' already at the alignment stage almost doubles the number of transcripts that can be measured reliably. rna?seq is listed by: OMICtools
has parent organization: University of Natural Resources and Life Sciences; Vienna; Austria
PMID:22485116 GNU General Public License OMICS_01261 SCR_004938 2026-02-14 02:01:01 1
Bambus
 
Resource Report
Resource Website
Bambus (RRID:SCR_005068) Bambus software resource Software for scaffolding to address some of the challenges encountered when analyzing metagenomes. Scaffolding represents the task of ordering and orienting contigs by incorporating additional information about their relative placement along the genome. While most other scaffolders are closely tied to a specific assembly program, Bambus accepts the output from most current assemblers and provides the user with great flexibility in choosing the scaffolding parameters. In particular, Bambus is able to accept contig linking data other than specified by mate-pairs. Such sources of information include alignment to a reference genome (Bambus can directly use the output of MUMmer), physical mapping data, or information about gene synteny. scaffolding is listed by: OMICtools
has parent organization: SourceForge
PMID:21926123 Open unspecified license OMICS_01432 http://sourceforge.net/apps/mediawiki/amos/index.php?title=Bambus SCR_005068 Bambus 2, Bambus 2.0 2026-02-14 02:00:50 0
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/
https://bio.tools/g-blastn
SCR_005062 2026-02-14 02:01:02 0
SLIDE
 
Resource Report
Resource Website
10+ mentions
SLIDE (RRID:SCR_005137) SLIDE software resource Software package that takes exon boundaries and RNA-Seq data as input to discern the set of mRNA isoforms that are most likely to present in an RNA-Seq sample. It is based on a linear model with a design matrix that models the sampling probability of RNA-Seq reads from different mRNA isoforms. To tackle the model unidentifiability issue, SLIDE uses a modified Lasso procedure for parameter estimation. Compared with deterministic isoform assembly algorithms (e.g., Cufflinks), SLIDE considers the stochastic aspects of RNA-Seq reads in exons from different isoforms and thus has increased power in detecting more novel isoforms. Another advantage of SLIDE is its flexibility of incorporating other transcriptomic data such as RACE, CAGE, and EST into its model to further increase isoform discovery accuracy. SLIDE can also work downstream of other RNA-Seq assembly algorithms to integrate newly discovered genes and exons. Besides isoform discovery, SLIDE sequentially uses the same linear model to estimate the abundance of discovered isoforms. is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
NIH ;
NHGRI HG004695;
NHGRI HG005639;
NEI EY019094
PMID:22135461 OMICS_01291 SCR_005137 sparse linear modeling of RNA-Seq data for isoform discovery and abundance estimation 2026-02-14 02:00:49 32
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-02-14 02:01:03 1
RetroSeq
 
Resource Report
Resource Website
10+ mentions
RetroSeq (RRID:SCR_005133) RetroSeq software resource A tool for discovery and genotyping of transposable element variants (TEVs) (also known as mobile element insertions) from next-gen sequencing reads aligned to a reference genome in BAM format. The goal is to call TEVs that are not present in the reference genome but present in the sample that has been sequenced. It should be noted that RetroSeq can be used to locate any class of viral insertion in any species where whole-genome sequencing data with a suitable reference genome is available. RetroSeq is a two phase process, the first being the read pair discovery phase where discorandant mate pairs are detected and assigned to a TE class (Alu, SINE, LINE, etc.) by using either the annotated TE elements in the reference and/or aligned with Exonerate to the supplied library of viral sequences. mobile element insertion, next-gen sequencing, bam, transposable element, genome, sequence is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:23233656 Acknowledgement requested, Open unspecified license OMICS_11232, OMICS_00120 SCR_005133 2026-02-14 02:00:51 45

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