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Proper Citation: RRID:MGI:4414940
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: cachexia, abnormal intestinal mucosa morphology, distended stomach, increased T cell apoptosis, abnormal myeloid leukocyte morphology, small intestinal villus atrophy, increased granulocyte number, intestinal obstruction, lymph node hypoplasia, premature death, spleen hypoplasia, thymus hypoplasia, decreased common myeloid progenitor cell number, abnormal crypts of Lieberkuhn morphology, abnormal colon morphology, abnormal B cell physiology, decreased leukocyte cell number, decreased granulocyte number, decreased bone marrow cell number, decreased B cell apoptosis, abnormal definitive hematopoiesis, decreased cell proliferation, decreased erythroid progenitor cell number, decreased double-positive T cell number, abnormal intestinal goblet cell morphology, abnormal intestinal epithelium morphology
Affected Gene: Gt(ROSA)26Sor, Elavl1
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No rating or validation information has been found for Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+; Elavl1tm1Thla/Elavl1tm1Thla.
No alerts have been found for Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+; Elavl1tm1Thla/Elavl1tm1Thla.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
