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Organism Name
Organism Information

URL: https://www.infrafrontier.eu/emma/strain-details/?q=6326

Proper Citation: RRID:IMSR_EM:06326

Description: Mus musculus with name STOCK Rag2tm1Fwa B2m H2-Ab1 Il2rg Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl from IMSR.

Species: Mus musculus

Synonyms: SURE-L1/Rag2°/°GammaC°/°. STOCK Rag2 B2m H2-Ab1 Il2rg Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl

Notes: gene symbol note: transgene insertion 1; Daniel M Altmann|histocompatibility 2; class II antigen A; beta 1|transgene insertion 1; Beatrice Perarnau|recombination activating gene 2|beta-2 microglobulin|interleukin 2 receptor; gamma chain; mutant strain: Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|H2-Ab1|Tg(HLA-A/H2-D/B2M)1Bpe|Rag2|B2m|Il2rg

Affected Gene: transgene insertion 1; Daniel M Altmann|histocompatibility 2; class II antigen A; beta 1|transgene insertion 1; Beatrice Perarnau|recombination activating gene 2|beta-2 microglobulin|interleukin 2 receptor; gamma chain

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Ratings and Alerts

No rating or validation information has been found for STOCK Rag2tm1Fwa B2m H2-Ab1 Il2rg Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human combined T cell and B cell immunodeficiency.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human X-linked severe combined immunodeficiency.

View More at BIOMED RESOURCE WATCH

Data and Source Information

Source: Integrated Animals

Source Database: European Mouse Mutant Archive