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Memorial Sloan Kettering Cancer Center Genome Editing and Screening Core Facility (RRID:SCR_027799)Copy Citation Copied
URL: https://www.mskcc.org/research/ski/core-facilities/genome-editing-screening
Proper Citation: Memorial Sloan Kettering Cancer Center Genome Editing and Screening Core Facility (RRID:SCR_027799)
Description: Core Facility provides functional genomics, highthroughput screening (HTS), and high-content screening (HCS) services toward the discovery of novel cancer targets and elucidation of complex, aberrant cellular pathways. Offers assistance and training in range of cloning, customized library design, lentivirus production, assay development, screening, and image analysis considerations to assist researchers in harnessing these powerful target identification tools and drug screening methodologies. Offers CRISPR-mediated transcriptional activation/interference (CRISPRa/CRISPRi) technologies combined with lentivirus delivery systems, customized stable isogenic cell line generation (knockout, HDR-directed knock-in, knockdown, base editing, and prime editing) toward the generation of unique cancer cell line models.
Resource Type: core facility, access service resource, service resource
Keywords: ABRF, functional genomics, highthroughput screening (HTS), high-content screening (HCS), discovery of novel cancer targets services,
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