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URL: http://caps.ncbs.res.in/MegaMotifbase/index.html
Proper Citation: MegaMotifbase (RRID:SCR_007775)
Description: A database of structural motifs for protein structures related at the family and-or superfamily level. Such motifs among structurally aligned proteins are recognized by the conservation of amino acid preference and solvent inaccessibility and are examined for the conservation of other important structural features like secondary structural content, hydrogen bonding pattern and residue packing. These motifs may form the common core by maintaining a particular spatial orientation pattern when compared across different proteins belonging to the same family or superfamily. Such motifs can also be employed to design and rationalize protein engineering and folding experiments. Therefore, the MegaMotifbase can be a useful resource to gain knowledge about structure and functional relationship of proteins. Alignments are available for download.
Synonyms: MegaMotifbase
Resource Type: data or information resource, database
Keywords: protein families, protein superfamilies
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