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URL: http://www.immuneprofiling.org/
Proper Citation: Human Immunology Project Consortium (RRID:SCR_001491)
Description: Consortium established to capitalize on recent advances in immune profiling methods in order to create a novel public resource that characterizes diverse states of the human immune system following infection; prior to and following vaccination against an infectious disease; or prior to and following treatment with an immune adjuvant that targets a known innate immune receptor(s). Through this program, well-characterized human cohorts are studied using a variety of modern analytic tools, including multiplex transcriptional, cytokine, and proteomic assays; multiparameter phenotyping of leukocyte subsets; assessment of leukocyte functional status; and multiple computational methods. Centralized research resources and a comprehensive, centralized database will be constructed for use by the greater scientific community. The information gained from the program will provide a comprehensive understanding of the human immune system and its regulation, and will reveal novel associations between components of the immune system and other biological systems, identify novel immune mediators and pathways, establish predictors of vaccine safety in different populations, and enable the rapid evaluation of different vaccine formulations and administration regimens in human populations.
Abbreviations: HIPC
Synonyms: immune profiling, immuneprofiling.org
Resource Type: data or information resource, organization portal, portal, consortium
Keywords: immune profiling, immune system, infection, vaccine, infectious disease, immune adjuvant, immune receptor, multiplex assay, phenotyping, systems biology, mass spectrometry, regulation, mediator, pathway, database, leukocyte, transcriptome, proteome
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