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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
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  • Genomic Alteration:wbgene00006843(unc-119) (facet)

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
juSi164 unc-119(ed3) III; wtfIs263.
 
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RRID:WB-STRAIN:WBStrain00062210 Caenorhabditis elegans juSi164 unc-119(ed3) III; wtfIs263. juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfIs263 [rab-3p::AI::ChR2(H134R)::unc-54 3'UTR + rab-3p::AI::Voltron::unc-54 3'UTR + rab-3p::his-24::tagBFP::unc-54 3'UTR]. Keep plates covered to avoid unnecessary exposure to light. Pan-neuronal expression of ChR2 (H134R) along with Voltron volatage indicator and nuclear-localized tagBFP. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062210 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:05 0
juSi164 unc-119(ed3) III; wtfIs335.
 
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RRID:WB-STRAIN:WBStrain00062213 Caenorhabditis elegans juSi164 unc-119(ed3) III; wtfIs335. juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfIs335 [5xQUAS+(delta)pes-10p::AI::eTsChR::unc-54 3'UTR + rab-3p::AI::QF+hGR::SL2::tagBFP::unc-54 3'UTR + rab-3p::his-24::tagRFP::unc-54 3'UTR + rab-3p::his-24::GCaMP6s::unc-54 3'UTR]. Keep plates covered to avoid unnecessary exposure to light. Pan-neuronal eTsChR on activation using dex treatment via QF+hGR. Worms also express calcium sensing fluorescence protein- GCaMP6s in nuclei of each neurons. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062213 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:05 0
juSi164 unc-119(ed3) III; wtfEx296.
 
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RRID:WB-STRAIN:WBStrain00062211 Caenorhabditis elegans juSi164 unc-119(ed3) III; wtfEx296. juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfEx296 [rab-3p::AI::gur-3G::unc-54 3'UTR + rab-3p::AI::prdx-2G::SL2::his-24::tagRFP::unc-54 3'UTR + rab-3p::his-24::GCaMP6s::unc-54 3'UTR]. Pick RFP+ to maintain. Keep plates covered to avoid unnecessary exposure to light. Worms expressing a purple light-sensitive optogenetic protein system: pan-neuronal expression of GUR-3 and PRDX-2 with nuclear-localized tagRFP and GCaMP6s. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062211 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:01 0
unc-119(kst33) III.
 
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Resource Website
RRID:WB-STRAIN:WBStrain00062249 Caenorhabditis elegans unc-119(kst33) III. Made_by: Mohammed Aljohani|"Maintain at 15C. Temperature-sensitive unc-119 allele. Wild-type at 15C, intermediate Unc and Egl at 20C, and fully penetrant Unc and Egl at 25C. For use in transgenesis, maintain the strain at lower temperatures for increased brood size and easier injection, then transfer animals to 25C to select for transgenic animals based on Unc rescue. Molecular characterization shows a complex allele with a 210 bp duplication from a nearby exon-intron junction, which introduces 12 amino acids and a putative splice donor at a consensus splice acceptor site. The phenotype is most likely caused by temperature-sensitive splicing defects based on RT-PCR. Reference: Aljohani M, et al. Arrayed oligo libraries: genome-wide DNA- and RNP-based platforms for templated and non-templated CRISPR-Cas9 editing in C. elegans. (Submitted)" WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062249 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:06 0
unc-119(ed3) III; aak-2(ok524) X; fphEx3.
 
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RRID:WB-STRAIN:WBStrain00062599 Caenorhabditis elegans unc-119(ed3) III; aak-2(ok524) X; fphEx3. fphEx3 [aak-2Ap::aak-2C::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. aak-2c isoform expressed from the aak-2a promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384. WBGene00006843(unc-119)|WBGene00020142(aak-2) WBGene00006843(unc-119), WBGene00020142(aak-2) WB-STRAIN:WBStrain00062599 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:19 0
unc-119(ed3) III; aak-2(ok524) X; fphIs1.
 
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RRID:WB-STRAIN:WBStrain00062596 Caenorhabditis elegans unc-119(ed3) III; aak-2(ok524) X; fphIs1. fphIs1 [aak-2Ap::aak-2A::GFP + unc-119(+)]. aak-2A isoform expressed with its own promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384. WBGene00006843(unc-119)|WBGene00020142(aak-2) WBGene00006843(unc-119), WBGene00020142(aak-2) WB-STRAIN:WBStrain00062596 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:19 0
unc-119(ed3) III; aak-2(ok524) X; fphEx1.
 
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Resource Website
RRID:WB-STRAIN:WBStrain00062597 Caenorhabditis elegans unc-119(ed3) III; aak-2(ok524) X; fphEx1. fphEx1 [aak-2Cp::aak-2C::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. aak-2C isoform expressed from its own promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384. WBGene00006843(unc-119)|WBGene00020142(aak-2) WBGene00006843(unc-119), WBGene00020142(aak-2) WB-STRAIN:WBStrain00062597 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:14 0
unc-119(ed3) III; aak-2(ok524) X; fphIs3.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00062601 Caenorhabditis elegans unc-119(ed3) III; aak-2(ok524) X; fphIs3. fphIs3 [rab-3p::aak-2A::GFP + unc-119(+)]. aak-2A isoform expressed from the neuronal rab-3 promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384. WBGene00006843(unc-119)|WBGene00020142(aak-2) WBGene00006843(unc-119), WBGene00020142(aak-2) WB-STRAIN:WBStrain00062601 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:08 0
rajSi50 II; unc-119(ed3) III.
 
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Resource Website
RRID:WB-STRAIN:WBStrain00062706 Caenorhabditis elegans rajSi50 II; unc-119(ed3) III. Made_by: Kathrin Theil|"rajSi50 [gld-1p::GFP::H2B::gld-1 3'UTR + Cbr-unc-119(+)] II. Maintain at 24C on OP50. Select well-fed adult animals with bright germline GFP in nuclei to propagate strain. GFP is visible in germline nuclei, low in distal germ cells, increases proximally, strong in oocytes. Kimble lab crossed original NIK50 strain with TX189 [oma-1::GFP] and back out again to reduce GFP silencing. Primers to confirm FBEa: slc314 GTCACCAAGTACACTTCCAGCAAG / slc311 TGGCAACATGATGTATGGCACA (100 bp band in FBEa wt). FBEb: slc314 GTCACCAAGTACACTTCCAGCAAG / slc304 GGGTTAGCGTTAAGATAACACA (~500 bp band in FBEb wt). References: Theil K, et al. Nature Commun. 2019 Sep 16;10(1):4205. doi: 10.1038/s41467-019-12050-7. PMID: 31527589. Carrick BH, et al. Dev Cell. 2024. PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062706 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:10 0
mirSi29 II; unc-119(ed3) III.
 
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Resource Website
RRID:WB-STRAIN:WBStrain00062767 Caenorhabditis elegans mirSi29 II; unc-119(ed3) III. Made_by: Neus Sanfeliu Cerdan|"mirSi29 [flp-18p::lox2272::mtagBFP2::tbb-2 3'UTR::lox2272::ACR1::SL2::jRGECO1a::let-858 3'UTR + Cbr-unc-119(+)] II. Blue fluorescence in flp-18 expressing neurons. Combine with CRE driven by a promoter co-expressed in flp-18 expressing cells to switch from blue expression to ACR1 and jRGECO1a expression. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062767 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:23 0
mirSi34 II; unc-119(ed3) III.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00062768 Caenorhabditis elegans mirSi34 II; unc-119(ed3) III. Made_by: Neus Sanfeliu Cerdan|"mirSi34 [myo-3p::lox2272::mtagBFP2::tbb-2 3'UTR::lox2272::ChR2-HRDC::SL2::jRGECO1a::let-858 3'UTR + Cbr-unc-119(+)] II. Blue fluorescence in body wall muscles. Combine with CRE driven by a promoter expressed in desired muscle cells to switch from blue expression to ChR2-HRDC and jRGECO1a expression. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062768 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:17 0
mirSi16 II; unc-119(ed3) III; mirIs110 V; mirIs107.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00062758 Caenorhabditis elegans mirSi16 II; unc-119(ed3) III; mirIs110 V; mirIs107. mirSi16 [flp-18p::lox2272::BFP::tbb-2 3'UTR::lox2272::ChR2-HRDC::SL2::jRGECO1a::unc-54 3'UTR + Cbr-unc-119(+)] II. mirIs110 [odr-7p::TeNL + unc-122p::GFP *oxTi553 [eft-3p::tdTomato::H2B::unc-54 3'UTR + Cbr-unc-119(+)]] V. mirIs107 [gpa:14p::CRE + npr-9p::ChR-HRDC::YFP::SL2::jRGECO1a + rps-0p::hygroR]. Blue fluorescence in flp-18 expressing neurons. Green coelomycetes segregates with calcium sensitive (Kd 250 nM) teal nanolantern (TeNL) in AWA. ChR2-HRDC and jRGECO1a in AVA (instead of BFP) and ChR2-HRDC::YFP and jRGECO1a in AIB. HygroR. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062758 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:23 0
mirSi16 II; unc-119(ed3) III.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00062759 Caenorhabditis elegans mirSi16 II; unc-119(ed3) III. mirSi16 [flp-18p::lox2272::BFP::tbb-2 3'UTR::lox2272::ChR2-HRDC::SL2::jRGECO1a::unc-54 3'UTR + Cbr-unc-119(+)] II. Blue fluorescence in flp-18 expressing neurons. Combine with CRE driven by a promoter co-expressed in flp-18 expressing cells to switch from blue expression to ChR2-HRDC and jRGECO1a expression. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062759 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:17 0
unc-119(ed3) III; qbcSi12 IV.
 
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Resource Website
RRID:WB-STRAIN:WBStrain00062750 Caenorhabditis elegans unc-119(ed3) III; qbcSi12 IV. qbcSi112 [elt-2p::GFP::his-58::3XmiR-228(mut)::tbb-2 3UTR + unc-119(+)] IV. Somatic miR-228 miRNA GFP reporter with a mutation in the miRNA-binding site. Reference: Dallaire et al. Dev Cell. 2018 Oct 22;47(2):239-247.e4. doi: 10.1016/j.devcel.2018.08.022. PMID: 30245155. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062750 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:17 0
unc-119(ed3) III; qbcSi11 IV.
 
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RRID:WB-STRAIN:WBStrain00062751 Caenorhabditis elegans unc-119(ed3) III; qbcSi11 IV. qbcSi11 [elt-1p::GFP::his-58::3XmiR-228::tbb-2 3UTR + unc-119(+)] IV. Somatic miR-228 miRNA GFP reporter. Reference: Dallaire et al. Dev Cell. 2018 Oct 22;47(2):239-247.e4. doi: 10.1016/j.devcel.2018.08.022. PMID: 30245155. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062751 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:11 0
unc-119(ed3) III; qbcSi10 IV.
 
Resource Report
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RRID:WB-STRAIN:WBStrain00062749 Caenorhabditis elegans unc-119(ed3) III; qbcSi10 IV. qbcSi10 [mex-5p::GFP::his-58::3XmiR-228(mut)::tbb-2 3UTR + unc-119(+)] IV. Germline-specific miR-228 miRNA GFP reporter with a mutation in the miRNA-binding site. Reference: Dallaire et al. Dev Cell. 2018 Oct 22;47(2):239-247.e4. doi: 10.1016/j.devcel.2018.08.022. PMID: 30245155. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062749 WormBase (WB) WB unknown EMPTY 2026-02-07 12:32:22 0
WH337
 
Resource Report
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RRID:WB-STRAIN:WBStrain00047006 Caenorhabditis elegans unc-119(ed3) III; ojIs27. EMPTY WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00047006 WormBase (WB) WB unknown EMPTY WB-STRAIN:WH337 2026-02-07 12:27:55 0
adeIs1 II; unc-119(ed3) III; ltIs37 IV.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00047202 Caenorhabditis elegans adeIs1 II; unc-119(ed3) III; ltIs37 IV. adeIs1 [mex-5::spd-1::GFP + unc-119(+)] II. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. Superficially wild-type. SPD-1::GFP and mCherry-tagged histones allow visualisation of chromatin with central spindle/midbody during cell divisions. Reference: Nahaboo W, et al. Mol Biol Cell. 2015 Jun 1;26(11):2020-9.|"adeIs1 [mex-5::spd-1::GFP + unc-119(+)] II. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. Superficially wild-type. SPD-1::GFP and mCherry-tagged histones allow visualisation of chromatin with central spindle/midobdy during cell divisions. Reference: Nahaboo W, et al. Mol Biol Cell. 2015 Jun 1;26(11):2020-9." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00047202 WormBase (WB) WB unknown PMID:32149606 2026-02-07 12:27:59 0
egxSi155 II; unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00047270 Caenorhabditis elegans egxSi155 II; unc-119(ed3) III. egxSi155 [mex-5p::tomm-20::mKate2::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of TOMM-20 tagged with mKate2 on the outer membranes of mitochondria in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Stephanie Miller"|"Supplementary_genotype egxSi155[mex-5p::tomm-20::mKate2::pie-1 3'UTR + unc-119(+)] II; unc-119(ed3) III" WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00047270 WormBase (WB) WB unknown PMID:37708895
PMID:38746662
2026-02-07 12:27:59 0
egxSi157 II; unc-119(ed3) III.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00047271 Caenorhabditis elegans egxSi157 II; unc-119(ed3) III. egxSi157 [mex-5p::tomm-20::Dendra2::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of TOMM-20 tagged with photoconvertible Dendra2 on the outer membranes of mitochondria in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Stephanie Miller" WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00047271 WormBase (WB) WB unknown EMPTY 2026-02-07 12:28:00 0

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