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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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  • Species:tetrahymena thermophila (facet)

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
B1KO-4
 
Resource Report
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RRID:TSC_SD02753 Tetrahymena thermophila Heterozygous germline transformant of BTUI knockout. Derived from Cu428 X B2086 transformed w/ BHAB-1(construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to BIKO-2. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. BTU1 (TTHERM_00348510) Micronucleus: H4-neo replaces coding of BTU1, heterozygous SD02753 BTU1/btu1[∆,::H4-neo]; MPR1-1/mpr1-1 TSC, Tetrahymena Stock Center TSC PMID:9037049
PMID:10831613
2026-02-14 07:55:07 0
BHM-1
 
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RRID:TSC_SD02236 Tetrahymena thermophila Progeny of DB6B x DB2A, transformed by BTU-HA TTMet construct. The transformants are dependent on Cadmium, 0.25ug/ml. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580) Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: HA c-terminal tagged BTU1 into MTT1 locus SD02236 btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]; MTT1/mtt1-?[∆(::BTU1)HAc]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:15254268
PMID:11864572
PMID:10831613
2026-02-14 07:55:07 0
RDP1-T1
 
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RRID:TSC_SD02512 Tetrahymena thermophila Shot plasmid pRDP1::TAG-neo3 #110 into conjugating CU428XB2086 but only got somatic strains, slow growth. No other information From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. RDR1 (TTHERM_00853150) Macronucleus: HA-FLAG tag of RDR1 SD02512 (pm-r, ?) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:07 0
UCB305
 
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RRID:TSC_SD03298 Tetrahymena thermophila sfr13 complete null rescue. First a 5' part of the gene was introduced into the sfr13 locus with BSR selection that included a 5'FLAG tag. Second, the remainder of the gene was introduced to the KO locus with the 5' BSR insertion, and rescue of the small cell size phenotype was selected for. From the Winey Lab at the University of Colorado Boulder. SFR13 (TTHERM_00522830) Micronucleus: cen2-1[∆::NEO2] Macronucleus: FLAG-SFR13 rescue in two parts (see comments) SD03298 sfr13-1[∆::NEO2] (sfr13-1[∆::NEO2]::SFR13[5'FLAG::BSR]::SFR13 3'; WT cell size and number of basal bodies., ?) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:06 0
NgoA KO-12
 
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RRID:TSC_SD02488 Tetrahymena thermophila It’s a homozygous clone of KO of NgoA gene in both mac and mic grew up from sinle cell. the KO construct is: Neo gene driven by MTT promoter(2.5kb), and this is in opposite direction in NgoA flanking. NgoA KO-12 can mate with NgoA KO-7 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. NgoA (TTHERM_00655890) Micronucleus: neo3 into NgoA coding Macronucleus: neo3 into NgoA coding SD02488 ngoA[∆::neo3]/ngoA[∆::neo3] (ngoA[∆::neo3] ; pm-r, NgoA KO, ?) TSC, Tetrahymena Stock Center TSC PMID:15870266 2026-02-14 07:55:07 0
CNB KO F2-1-13 (1)
 
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RRID:TSC_SD02761 Tetrahymena thermophila Homozygote CnjB KO Homokaryon. Partial cnjB coding sequences were replaced by neo3. This strain was supposed to be pm-r but thawed pm-s. From the Gorovsky lab, University of Rochester. CnjB (TTHERM_01091290) Micronucleus: Neo3 replaces part of coding Macronucleus: Neo3 replaces part of coding SD02761 cnjB[∆?::neo3]/ cnjB[∆?::neo3] (cnjB[∆?::neo3], ?) TSC, Tetrahymena Stock Center TSC PMID:19596782 2026-02-14 07:55:07 0
double eri1+ twi1 5’ neo B1
 
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RRID:TSC_SD02007 Tetrahymena thermophila Eri1 KO construct was shot into twi1 KO homozygous homokaryon (Neo3 gene is lost in mac, strain is pm-s). From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. ERI1 (TTHERM_00501020) Micronucleus: TWI1 ko Macronucleus: twi1 kO and ERI1 KO SD02007 twi1[∆?::neo3]/twi1[∆?::neo3] (twi1[∆?::neo3]; eri1[∆?::neo3]; same as ∆Twi1) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:06 0
19882-2
 
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RRID:TSC_SD01556 Tetrahymena thermophila Collected by Paul Doerder on 8/26/2008 from the pond designated SG69-1 in Guys Mills, PA (lat. 41 37.174, long. -79 55.095, elevation 1549 ft, nearest road is Carpenter Road). Geographical area: Western Pennsylvania Collection number: 893 Has a micronucleus. Cech's self-splicing intron is present. Cytochrome oxidase I haplotype = ANF1 SD01556 (VI) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:06 0
∆H3 gl 2.2
 
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RRID:TSC_SD01955 Tetrahymena thermophila This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series. From the Gorovsky lab, University of Rochester. HHT2 (TTHERM_00189180), HHF2 (TTHERM_00189170) Micronucleus: Neo2 ko of HHT1 and HHT2/HHF2 SD01955 hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; mp-r, ?) TSC, Tetrahymena Stock Center TSC PMID:16908532 2026-02-14 07:55:07 0
ATU-4D
 
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RRID:TSC_SD01837 Tetrahymena thermophila It is a progeny of conjugants of AAK02.7XAAKO5.5 transformed with pATU-4D derived from pTUB100E3-PvuII (linearized)where the ATU1 gene is marked with Hae III and Pvu II sites and E443D, E445D,E446D,E447D From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. ATU1 (TTHERM_00558620) Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E443D, E445D, E446D, E447D or neo replacing coding of some ATU1 genes SD01837 atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E443D,E445D E446D,E447D]; ATU1 with E443D, E445D,E446D,E447D or neo replacing coding of some ATU1 genes, pm-r, cy-s,mp-? ) TSC, Tetrahymena Stock Center TSC PMID:10831613
PMID:9037049
2026-02-14 07:55:06 0
BLTGL5-1
 
Resource Report
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RRID:TSC_SD02250 Tetrahymena thermophila BLT germline heterokaryon, homozyous KO in mic, pm sensitive (120 ug/ml). Cd induced Neo cassette (1.2 ug/ml)--MTT promoter, Neo coding, BTU2 terminator. Construct pBLTMKO, Mates with BLTGL1-3,4,5 and 2-5. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. BLT1 (TTHERM_01104960) Micronucleus: Neo3 replaces BLT coding SD02250 blt1-1[∆,neo3]/ blt1-1[∆,neo3]; MPR1-?/ MPR1-? (BLT1; mpr1-1; mp-r, ?) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:06 0
CU5041
 
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RRID:TSC_SD01166 Tetrahymena thermophila SD01166 chx1-1/chx1-1; pmr1-1/pmr1-1; Del 5 (CHX1; pmr1-1; cy-s, pm-r, II) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:06 0
T146VHA #1
 
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RRID:TSC_SD02531 Tetrahymena thermophila pT146V-HA rescued GTUKO 5x6 progeny having mutation @ GTU1 T146V gene, driven by MTT1 promoter. Needs Cd to induce. Has HA tag at c-terminus. Single cell (a) These are same as previous ones, but new transformants, (one week old) not single celled and haven’t tested genotype yet From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. GTU1 (TTHERM_00079520) Micronucleus: Neo2 into GTU1 locus Macronucleus: GTU1 with mutation T146V and c-terminus HA tag into the MTT1 locus, partial replacement. SD02531 gtu1[∆::neo2]/ gtu1[∆::neo2] (gtu1[∆::neo2]; MTT1/mtt1[∆, HAc(::GTU1, T146V)]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:16344310
PMID:12356864
2026-02-14 07:55:06 0
CU5040
 
Resource Report
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RRID:TSC_SD01165 Tetrahymena thermophila SD01165 chx1-1/chx1-1; pmr1-1/pmr1-1; Del 5 (CHX1; pmr1-1; cy-s, pm-r, II) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:07 0
SJ188
 
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RRID:TSC_SD01603 Tetrahymena thermophila Complementation group could not be determined because of sterility of the mutant. Submitted by Eduardo Orias, University of California, Santa Barbara SD01603 mpr1-1/mpr1-1, vac?/vac? (mpr1, vac?; mp-r, vac-, oral apparatus-, contractil vacuole pore-, rounded, IV) TSC, Tetrahymena Stock Center TSC PMID:17248939 2026-02-14 07:55:07 0
IA317
 
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RRID:TSC_SD01451 Tetrahymena thermophila Formation of a fourth membranelle in the oral apparatus. Located on chromosome 3, probably 3L. Allelic to mpC-1 (IA308), with similar oral expression and no pleiotropic effects on cell division. Penetrance increased at higher temperatures. Submitted by Joseph Frankel, University of Iowa MPC (membranellar pattern C) SD01451 mpC-2/mpC-2 (mpC-2, VII) TSC, Tetrahymena Stock Center TSC PMID:6491586
PMID:18658256
2026-02-14 07:55:07 0
BTU1-94c (G3-B)
 
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RRID:TSC_SD02269 Tetrahymena thermophila Somatically transformed VB1 cells with BTU1 p94c construct. p94c changes MREI at begining of coding to remove the REI. Also put the missing “C” back into the BTU1 coding region (~ position + 1040) From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. BTU1 (TTHERM_00348510) Macronucleus: Removed the amino acids REI at positions 2, 3, 4 ibeta tubulin 1 gene SD02269 mic still from VB1 cell (btu1[∆2,3,4]/btu1[∆2,3,4]; BTU1 has M--- ( REI removed at start of coding); no longer taxol hypersensitive or oryzalin resistant since back to wt L350) TSC, Tetrahymena Stock Center TSC PMID:7910408 2026-02-14 07:55:07 0
∆H3 gl 10.6
 
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RRID:TSC_SD02148 Tetrahymena thermophila This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series All the 10.* series are separate cell lines. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170) Micronucleus: Neo2 KO of HHT1 and HHT2/HHF2 SD02148 hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; mp-r, ?) TSC, Tetrahymena Stock Center TSC PMID:16908532 2026-02-14 07:55:07 0
IA475
 
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RRID:TSC_SD01579 Tetrahymena thermophila This clone combines a temperature-sensitive fission arrest with a hypoangular phenotype. It was used to generate and investigate "left handed" hypoangular cells Submitted by Joseph Frankel, University of Iowa HPO1(hypoangular1), CDAA (cell division arrestA) SD01579 hpo1-2/hpo1-2; cdaA-2/cdaA-2 (hpo1-2; cdaA-2; hpo1-2, cdaA-2, III) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:07 0
HTA1-D13E1
 
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1+ mentions
RRID:TSC_SD02390 Tetrahymena thermophila G4B1G10A x G4B3C1A. mutated HTA1 rescue ∆HTA1∆HTA2 double knockout heterokaryon. No H2A.1 ubiquitination . Can mate with D13D1. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500) Micronucleus: Neo 2 knockout of HTA1 and HTA2 genes Macronucleus: mutated HTA1 SD02390 hta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (hta1[ K125R]; hta2[∆::neo2]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:11430834
PMID:12665578
2026-02-14 07:55:06 1

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