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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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On page 5 showing 81 ~ 100 out of 2,014 results
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    • RRID:TSC_SD02090

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[K4Q] ; htb2 [∆::neo2]; pm-r, ?)
Affected Genes: HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180)
Genomic Alteration: Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: Mutated HTB1 with K4Q
Availability:
References:
Synonyms:
Notes: ∆∆HTB knockout heterokaryons rescued by htb1-K4Q. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD02090 Copy   

    • RRID:TSC_SD03107

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: (?)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Collected by Paul Doerder on 7/24/2009 from the pond designated Willard Pond in NH (latitude 43.02, longitude -72.02) Has a micronucleus. Mated with < 6 testers.

Proper citation: RRID:TSC_SD03107 Copy   

    • RRID:TSC_SD02819

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpr1-1/mpr1-1 (MTT1/mtt1-?[5’neo2, ∆, HAHAn(::PPO1)]; pm-r, VII)
Affected Genes: PPO1 (TTHERM_00865290, TTHERM_00865300)
Genomic Alteration: Macronucleus: PPO1 gene with 2 HA tags at n-terminus partially replace MTT1 coding, also neo2 in 5’ flanking region of MTT1.
Availability:
References:
Synonyms:
Notes: Used Xiayuan Song’s pXS 75 construct: neo 2 in 5 flank of MTT1 gene. 2 HA tags right after ATG. then PP50 coding sequence. PP50 is Ttherm. 00865300 into Ttherm 00865290 sequence. Need 100ug/ml pm in medium to keep the tagged gene present. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD02819 Copy   

    • RRID:TSC_SD01571

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: janB-1/janB-1; bcd1-1/bcd1-1 (janB-1; bcd1-1; janB, bcd1, II)
Affected Genes: JANB (janusB), BCD1 (broadened cortical domains1)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: A complex combination of additivity, enhancement of the janus phenotype, and suppression of one aspect of the bcd phenotype (broadened oral domains). Described in detail in Cole et al. (1988). Submitted by Joseph Frankel, University of Iowa

Proper citation: RRID:TSC_SD01571 Copy   

    • RRID:TSC_SD02387

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2 (HTAX/htax[∆::neo2]; hta1[∆::neo2]; pm-r, mp-r, ?)
Affected Genes: HTA1 (TTHERM_00790790)
Genomic Alteration: Micronucleus: KO of HTAX and HTA1 with neo2 Macronucleus: Complete KO of HTA1 with neo2, Partial replacement of HTAX with neo2
Availability:
References:
Synonyms:
Notes: New batch, rescue of h∆∆HTA-A1F14A1 and B1G6A These are KO of the major HTA genes HTAX and HTA1 in the mic with HTAX partial in the mac. Not mating type II,V1I or VII; same as HTA1-B1a. From the Gorovsky lab, University of Rochester.

Proper citation: RRID:TSC_SD02387 Copy   

    • RRID:TSC_SD01973

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/Chx1-1[C3]; MAT2/MAT3 (chx1-1; MAT3; cy-r, I)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Not useful for mapping loci on MIC chromosome 3R. One parent was missing this chromosome arm, so the progeny were not heterozygous. Submitted by Eduardo Orias, University of California, Santa Barbara

Proper citation: RRID:TSC_SD01973 Copy   

    • RRID:TSC_SD00762

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1; pmr1-1/pmr1-1; Del 1L (CHX1; pmr1-1; cy-s, pm-r, II)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Large deletion. May be missing entire left arm of chromosome 1.

Proper citation: RRID:TSC_SD00762 Copy   

    • RRID:TSC_SD01342

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: gtu1[∆::neo2]/gtu1[∆::neo2] (gtu1[∆::neo2]; MTT1/mtt1[∆::GTU1,HAc]; pm-r, ?)
Affected Genes: GTU1 (TTHERM_00079520)
Genomic Alteration: Micronucleus: GTU1 replaced by neo2 Macronucleus: GTU1with c-terminal HA tag into MTT1 locus, partial replacement
Availability:
References:
Synonyms:
Notes: In mac at GTU locus, GTU coding region is replaced by neo cassette. At metallothionein locus, two alleles a) MTT coding region, b) GTU coding region with HA tag .Progeny of GTUKO5x6, transformed with pTTMGHA construct (GTU coding, HA tag driven by MTT promoter) to rescue GTU KO heterokaryon. Can mate with cTTMG-HA #12 or #14. Requires Cd to grow, use .25 to 1 ug/ml. GTU1-HA detected at protein level. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD01342 Copy   

    • RRID:TSC_SD02796

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpr1-1/mpr1-1 (cnjB[5’neo3,HAn]; pm-r, VII)
Affected Genes: CnjB (TTHERM_01091290)
Genomic Alteration: Macronucleus: Ha tagged CnjB with neo3 upstream
Availability:
References:
Synonyms:
Notes: Somatic HA-CnjB. HA sequence was inserted to just after the start codon. Neo3 was inserted upstream of CnjB. Background: Cu428. Grow in 0.5 to 1.0 ug/ml CdCl2 and 100 ug/ml paromomycin. From the Gorovsky lab, University of Rochester.

Proper citation: RRID:TSC_SD02796 Copy   

    • RRID:TSC_SD02711

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpr1-1/mpr1-1 (rnh1.3[HA]; pm-r, VII)
Affected Genes: RNH13 (TTHERM_00283900)
Genomic Alteration: Macronucleus: RNH1.3 with HA tag
Availability:
References:
Synonyms:
Notes: All Somatic RNH1.3 was replaced by RNH1.3 HA construct. Not sure where the neo3 is. CU428 background. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD02711 Copy   

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: htay[∆123-388::neo3]/htay[∆123-388::neo3] (VI)
Affected Genes: HTAY (TTHERM_01079200)
Genomic Alteration: Micronucleus: Neo3 ko of last 2/3 (AA123-388) of HTAY gene
Availability:
References:
Synonyms:
Notes: Knockout Heterokaryon of HTAY gene. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD02679 Copy   

    • RRID:TSC_SD01226

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: chx1-1/chx1-1 (CHX1; cy-s, III)
Affected Genes: CHX1
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Submitted by Joseph Frankel, University of Iowa

Proper citation: RRID:TSC_SD01226 Copy   

    • RRID:TSC_SD01229

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpC-1/mpC-1 (mpC-1, V)
Affected Genes: MPC (membranellar pattern C)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Formation of a fourth membranelle in the oral apparatus, with increased penetrance at higher temperature. Located on chromosome 3, probably 3L. The published phenotypic analysis was carrried out on a different homozygous clone that is now extinct. Submitted by Joseph Frankel, University of Iowa

Proper citation: RRID:TSC_SD01229 Copy   

    • RRID:TSC_SD01902

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E443A, E445A,E446A ]; pm-r, mp-? , ?)
Affected Genes: ATU1 (TTHERM_00558620)
Genomic Alteration: Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E443A, E445A, E446A or neo replacing coding of some ATU1 genes
Availability:
References:
Synonyms:
Notes: It is a progeny of conjugants of AAK02.7 X AAKO5.5 transformed with pATU-E443,445-6A derived from pTUB100E3-PvuII (linearized) where the ATU1 gene is marked with Hae III and Pvu II sites and E443A, E445A,E446A. From the Gorovsky lab, University of Rochester.

Proper citation: RRID:TSC_SD01902 Copy   

    • RRID:TSC_SD01749

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: cdaE-4/cdaE-4 (cdaE-4; cdaE, III)
Affected Genes: CDAE (cell-division-arrest E)
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: Allelelic to cdaE-1 (IA137) and cdaE-3 (IA225). The extinct cdaE-4 IV sister clone showed identical phenotype, similarly high (possibly higher) expression at 39°C. compared to IA137 (Sister clone to IA312). Submitted by Joseph Frankel, University of Iowa

Proper citation: RRID:TSC_SD01749 Copy   

    • RRID:TSC_SD01908

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: BTU2/btu2[∆,::H4-neo]; MPR1-1/mpr1-1 (BTU2/btu1[∆,::H4-neo]; MPR1-1/mpr1-1; mp-r, pm-r, ?)
Affected Genes: BTU2 (TTHERM_00836580)
Genomic Alteration: Micronucleus: H4-neo replaces BTU2 coding Macronucleus: H4-neo replaces BTU2 coding
Availability:
References:
Synonyms:
Notes: Heterozygous germline transformant of BTU2 knockout. Derived from Cu428 X B2086 transformed w/ BHAB-2 (construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to B2KO-6. Created 12/29/97, in soybean until 4/98. B2KO-6 mates with B2KO-1,2,3,4,5,7,8. No others mated. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD01908 Copy   

    • RRID:TSC_SD02201

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mpr1-1/mpr1-1 (HTAY/htay[∆ ::neo3]; MTT1/mtt1[5’neo2, ∆ :: 2HAn,(HTAY1-258, HTAX1-138)]; pm-r, VII)
Affected Genes: HTAY (TTHERM_01079200) and HTA1 (TTHERM_00790790)
Genomic Alteration: Macronucleus: Neo3 into HTAY, Chimeric YN-HTAX into MTT1 locus
Availability:
References:
Synonyms:
Notes: Shot Xiaoyuan Song’s i∆HTAY strain(partial replacement of HTAY with neo3) with construct MTT1-2HA tags after the ATG of HTAY n-terminus (AA1-258) followed by HTAX AA1-138) also has neo2 in 5’ flank of MTT1.Single cell line (3D) with most or all of HTAY replaced by the HA tagged YN-HTAX. Pushed to 30mg/ml pm resistance with Cd at 0.1-.0.5 ug/ml needed to express the YN-HTAX From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD02201 Copy   

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; pm-s, mp-r, ?)
Affected Genes: HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170)
Genomic Alteration: Micronucleus: Neo2 KO of HHT1 and HHT2/HHF2
Availability:
References:
Synonyms:
Notes: This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series All the 2.* series are separate cell lines. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD01872 Copy   

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; pm-s, mp-r, ?)
Affected Genes: HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170)
Genomic Alteration: Micronucleus: Neo2 KO of HHT1 and HHT2/HHF2
Availability:
References:
Synonyms:
Notes: This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.

Proper citation: RRID:TSC_SD01871 Copy   

    • RRID:TSC_SD01755

https://sites.wustl.edu/tetrahymena/finding-strains/

Source Database: TSC, Tetrahymena Stock Center
Genetic Background: mat1-2 (IV)
Affected Genes:
Genomic Alteration:
Availability:
References:
Synonyms:
Notes: A representative of the latest inbred generation of the B strain derived in the Frankel lab (by Leslie Jenkins). It was not used in any crosses with mutant clones. Submitted by Joseph Frankel, University of Iowa

Proper citation: RRID:TSC_SD01755 Copy   

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