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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588572
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00730 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588585
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: The transgene contains Cre recombinase expressed from cFos promoter and controllable by Tet activator/repressor Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00736 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9854709
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: This congenic strain was generated by introgressing the desired fragment from WKY/NCruk onto the genetic background of SHR/NCruk Rat Resource and Research Center
Proper citation: RRID:RRRC_00738 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358303
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00645 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290081
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Notes: this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center
Proper citation: RRID:RRRC_00367 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358300
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: This transgenic strain carries a copy of mouse Rhodopsin gene with a proline to histidine substitution at codon 23 (c.68C>A). Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00641 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482674
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: The Occidental HiS (high-saccharin-consuming) rat strain was developed from a male Holtzman Sprague-Dawley rat that voluntarily consumed high levels of saccharin.This male was mated to several Holtzman Sprague-Dawley females and offspring displaying high saccharin consumption were selected. Selective breeding was continued in which offspring with high saccharin consumption were bred. To maintain the outbred status of this colony the donor backcrosses to Hsd:SD every 4-6 generations. Rat Resource and Research Center
Proper citation: RRID:RRRC_00366 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290137
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Notes: this Sleeping Beauty mutants were derived by crossing F344-Tg(T2/Bart3)2Ceb and F344-Tg(PGK2-SB11)Ceb Rat Resource & Research Center
Proper citation: RRID:RRRC_00361 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482286
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: insertion of EGFP transgene with Ubiquitin C promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00086 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482284
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Notes: insertion of EGFP transgene with Ubiquitin C promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00084 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155663560
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: CRISPR/Cas9 technology was used to insert an IRES for iCre expression after the final coding sequence of exon 6 of the rat Gcg gene, before the 3' UTR. Rat Resource and Research Center
Proper citation: RRID:RRRC_00983 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578698
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for 24 generations for low hypnotic response to high dose ethanol, then inbred Rat Resource and Research Center
Proper citation: RRID:RRRC_00081 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578696
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for 24 generations for low sensitivity to ethanol then inbred. Rat Resource and Research Center
Proper citation: RRID:RRRC_00080 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=728193
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: outbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: To N 1945 from Sprague Dawley, Inc. Colony closed since then. NIH Autoimmune Rat Model Repository and Development Center, Rat Resource and Research Center
Proper citation: RRID:RRRC_00239 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578701
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for high ethanol sensitivity for 24 generations, then inbred. Rat Resource and Research Center
Proper citation: RRID:RRRC_00079 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578700
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm
References:
Synonyms:
Notes: Selectively bred for high sensitivity for ethanol hypnosis for 24 generations then inbred Rat Resource and Research Center
Proper citation: RRID:RRRC_00077 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695058
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: frame shift deletion in an exon 12 of Add3 gene causing a stop codon and loss of function. SD outbred background. Rat Resource and Research Center
Proper citation: RRID:RRRC_00792 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=151667414
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: This model expresses cre-recombinase under the control of the endogenous Ckm (creatine kinase, M-type) promoter. Cre was targeted to the rat Ckm gene of LE embryos through CRISP/Cas9 system genome editing system. Rat Resource and Research Center
Proper citation: RRID:RRRC_00951 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13450922
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Genetically Epilepsy-Prone Rats (GEPR-3) have moderate levels of seizure predisposition. This colony,initially referred to as an AGS (audiogenic response score) colony, was bred to exhibit clonic convulsions (moderate seizures with an ARS of 3) following a single wild running phase in response to sound. Siezures model human generalized tonic/clonic seizures. Rat Resource and Research Center
Proper citation: RRID:RRRC_00798 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=151356950
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Initial SD rats were then bred onto Wistar background for >10 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center
Proper citation: RRID:RRRC_00952 Copy
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