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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2302653
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 18th intron of the Mov10 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00377 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2302657
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm; Cryorecovery (as of 2024-04-16)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 4th intron of the Orc3 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00375 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2301700
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 2nd intron of the Spata13 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00373 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358632
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2019-02-20)
References:
Synonyms:
Notes: This strain has been selected for high open-field defecation (a test of emotional reactivity). The underlying genetic basis for this phenotype is not known. Originally selected by Broadhurst in 1954 for high open-field defacation (OFD) response in an open field. By Broadhurst to Harrington at the University of Northern Iowa at generation 25 in 1965. Rat Resource and Research Center
Proper citation: RRID:RRRC_00691 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290160
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 15th intron of the Rph3a gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00326 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566458
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2019-07-01)
References:
Synonyms:
Notes: F344 embryos were microinjected with R26-hPAP trangene which comprises of 0.8 kb genomic sequence of ROSA 26 promoter fused to human placental alkaline phosphatase (hPAP, ALPP). Rat Resource and Research Center
Proper citation: RRID:RRRC_00048 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1641865
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2016-12-01)
References:
Synonyms:
Notes: 9 week-old male rats were injected with ENU (N-ethyl-N-nitrosourea) and then bred. Phenotypically variant pups were visually identified and screened. Nonsense transversion mutation at nucleotide T4254 that converted TAT (tyrosine) to TAA (stop codon). Rat Resource and Research Center
Proper citation: RRID:RRRC_00286 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=737703
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-07-08)
References:
Synonyms:
Notes: Lewis from CRL were used as the background strain. This strain was made by pronuclear injection into Lewis embryos. The embryos were coinjected with DNA fragments containing the HLA-B*0702 human gene and the human beta-2-microglobulin gene. Founder 120-4 was selected and carrier animals from this founder were mated and this strain was bred to homozygosity. Rat Resource and Research Center
Proper citation: RRID:RRRC_00042 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2293354
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: segment of interest of chr 16 from WKY/NCrl was introgressed into LEW/SsNHsd Rat Resource and Research Center
Proper citation: RRID:RRRC_00708 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358277
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-07-16)
References:
Synonyms:
Notes: Developed by crossing an inbred RCS (rdy/rdy) with a cesarian developed Fischer (+/+) rat (from Charles River). The normal rats(+/rdy) were backcrossed to the RCS and the procedure repeated. Retinal Degeneration Rat Model Resource , Rat Resource and Research Center
Proper citation: RRID:RRRC_00317 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1299875
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2019-02-19)
References:
Synonyms:
Notes: Congenic strain created by backcrossing F344/NHsd into DA/BklArbNsi 9 times then brother-sister mating to maintain in the homozygous state Rat Resource and Research Center
Proper citation: RRID:RRRC_00679 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2302652
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 2nd intron of the Pde4d gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00436 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=70509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm
References:
Synonyms:
Notes: Curtiss and Dunning 1920 at Columbia University Institute for Cancer Research,To Heston 1949 (Billingham and Silvers 1959). To National Institutes of Health in 1951 (Hansen et al 1982). Subsequent sublines from Dunning or NIH. NIH Autoimmune Rat Model Repository and Development Center, Rat Resource and Research Center
Proper citation: RRID:RRRC_00158 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1579910
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. N117S mutation is generated from the codon change AAT/AGT. Rat Resource and Research Center
Proper citation: RRID:RRRC_00399 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290103
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: this Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb and F344-Tg(PGK2-sb11)Ceb. This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Nrg1 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00343 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2292452
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the Syndig1 gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00342 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1300439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-07-10)
References:
Synonyms:
Notes: This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into SD rat embryos. Animals that exhibited fluorescence of tails where then mated. The colony was transferred from Carlos Lois, California Institute of Technology, Pasedena, California to the Rat Resource and Research Center in 2002. This strain has been maintained by backcrossing carrier males to SD stock females in order to segregate transgenes and maintain the SD background. The strain now carries a single transgene which is located at chromosome 14q21. Rat Resource and Research Center
Proper citation: RRID:RRRC_00065 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2298772
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-12-14)
References:
Synonyms:
Notes: Sparse fuzzy hair animals with Wistar Furth background found at Tulane University to Skin and Cancer Hospital, Temple University, Philadelphia to Harlan (1987) Rat Resource and Research Center
Proper citation: RRID:RRRC_00340 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358180
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: consomic
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-05-07)
References:
Synonyms:
Notes: A FHH genomic background with a BN chromosome 19 introgressed. Rat Resource and Research Center
Proper citation: RRID:RRRC_00581 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290135
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 2nd intron of the Chsy1. Rat Resource and Research Center
Proper citation: RRID:RRRC_00337 Copy
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