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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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htb1-K115R-A2a Resource Report Resource Website |
RRID:TSC_SD02469 | Tetrahymena thermophila | New batch, rescue of progeny h∆∆HTB86B4A6 and D2A2. Not mating type II,VI,VII. From the Gorovsky lab, University of Rochester. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 into coding of HTB1 and HTB2 Macronucleus: HTB1 with K115R, HTB2 KO with neo2 | SD02469 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[K115R]; htb2 [∆::neo2]; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2026-02-14 07:54:51 | 0 | ||||
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CenP A-KO-3* Resource Report Resource Website |
RRID:TSC_SD01933 | Tetrahymena thermophila | Germline CenPA KO heterokaryon. CenPA coding is replaced by neo2. Star side. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | CNA1 (TTHERM_00146340) | Micronucleus: Neo2 into CNA1 | SD01933 | cna1[∆::neo2]/cna1[∆::neo2] (?) | TSC, Tetrahymena Stock Center | TSC | PMID:16738316 | 2026-02-14 07:54:51 | 0 | ||||
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BMCG-B2086 Resource Report Resource Website |
RRID:TSC_SD01812 | Tetrahymena thermophila | Centromeric H3 protein, green by IF. Partial mac replacement of MTT1 gene with GFP c-terminal tagged CNA1 gene. Thaw cells without drugs, then grow them in 60-100ug/ml blasticidin, Use 0.5-1 ug/ml cadmium chloride to express and see the green centromere. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | CNA1 (TTHERM_00146340), CenH3, CENP-A | Macronucleus: GFP tagged CNA1 from the MTT1 locus | SD01812 | in B2086 (MTT1/mtt1-?[5’ bsr1,∆,(::CNA1), GFPc]; Cna1p-GFPc, green centromeres, II) | TSC, Tetrahymena Stock Center | TSC | PMID:16738316 | 2026-02-14 07:54:52 | 0 | ||||
|
K5E5-2 Resource Report Resource Website |
RRID:TSC_SD02476 | Tetrahymena thermophila | Complete somatic tranformant of CU428 cells with pHHO5K /neo construct. Phosphorylation sites 1- 5 of H1 changed to glutamic acid and 5 other sites changed to lysines, neo 2 cassette in 3’ flanking region for selection. See paper. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHO1 (TTHERM_00823720) | Macronucleus: Change Threonine 35, 47, 54 and serine 43, 45 to glutamic acid (charge patch) and T60K, I64K, H65K, T67K, T69K | SD02476 | mpr1-1/mpr1-1 (hho1[3’neo2, T35E, S43E, S45E, T47E, T54E, T60K,I64K, H65K,T67K,T69K]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:11972045 PMID:10983971 |
2026-02-14 07:54:52 | 0 | ||||
|
18282-4 Resource Report Resource Website |
RRID:TSC_SD01547 | Tetrahymena thermophila | Collected by Paul Doerder on 8/21/2002 from the pond designated CRWP in Ridgway, PA (lat. 41 25.052, long. -78 51.876, elevation 1613 ft). Used Geko GPS. Geographical area: Allegheny National Forest Collection number: 453 No micronucleus present. | SD01547 | (?) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:54:51 | 0 | |||||||
|
htb1-A1G-A7b Resource Report Resource Website |
RRID:TSC_SD02083 | Tetrahymena thermophila | ∆∆HTB knockout heterokaryons rescued by htb1-A1G. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: Mutated HTB1 with A1G | SD02083 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[A1G] ; htb2 [∆::neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2026-02-14 07:54:52 | 0 | ||||
|
HTA1+2 (G4B1G10A) Resource Report Resource Website |
RRID:TSC_SD01391 | Tetrahymena thermophila | G115B5xG204F2. HTA1, HTA2 double germline knockout heterokaryon. Can mate with G4A1F14A, G4B3C1A From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500) | Micronucleus: Neo 2 knockout of HTAX and HTA1 genes | SD01391 | hta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (mp-r, II) | TSC, Tetrahymena Stock Center | TSC | PMID:11430834 PMID:12665578 |
2026-02-14 07:54:51 | 0 | ||||
|
∆HTB1-9-11B3 Resource Report Resource Website |
RRID:TSC_SD02082 | Tetrahymena thermophila | ∆HTB1 knockout. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360) | Micronucleus: neo2 KO of HTB1 Macronucleus: KO of HTB1 with neo2 | SD02082 | htb1[∆::neo2]/htb1[∆::neo2] (htb1[∆::neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2026-02-14 07:54:52 | 0 | ||||
|
122∆172∆H4ns Resource Report Resource Website |
RRID:TSC_SD01790 | Tetrahymena thermophila | IFT122 and IFT172 double KO heterokaryon From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | IFT122 (TTHERM_00694540), IFT172 (TTHERM_00089240) | Micronucleus: Neo3 into coding of IFT122A and of IFT172 | SD01790 | ift122[∆::neo3]/ift122[∆::neo3]; ift172[∆::neo3]/ift172[∆::neo3] (WT; pm-?, mp-?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:18211962 PMID:18199688 |
2026-02-14 07:54:52 | 0 | ||||
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AAA2D9 Resource Report Resource Website |
RRID:TSC_SD01834 | Tetrahymena thermophila | Progeny of DB6B x DB2A, co- transformed by constructs BTU1-D9 with (E431-442D) and construct of chimeric ATU1 gene, AAA2 duplicate ATU C-tail). See publications From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580), ATU1 (TTHERM_00558620) | Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: BTU2 replaced by bsr. BTU1 partially replaced by neo1, some replaced by BTU1-D9 with (E431-442D). Some ATU1 replaced by ATU1 with duplicate C-tail | SD01834 | btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]/ btu1-?[E431D,E432D,E433D,E435D,E437D,E438D,E439D,E440D,E442D]; ATU1/atu1-1[duplicate ATU1 tail--AAA2]; pm-r, Original BTU2 is replaced by bsr1, BTU1 coding replaced by neo1, then transformed with BTU1 with (E431-442D) and Chimeric ATU1 gene, AAA2 (duplicate ATU C-tail)) | TSC, Tetrahymena Stock Center | TSC | PMID:11864572 PMID:10831613 PMID:15254268 |
2026-02-14 07:54:51 | 0 | ||||
|
HA-hv2 (9) Resource Report Resource Website |
RRID:TSC_SD02648 | Tetrahymena thermophila | HA-tagged hv2 transformant. Checked by western blot and immunofluorescent staining From the Gorovsky lab, University of Rochester. | HHT3 (TTHERM_00016170) | Macronucleus: N-terminal HA tag of HHT3, not sure if complete replacement | SD02648 | mpr1-1/mpr1-1 (?HHT3/hht3[3’neo2, HAn]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:9343391 PMID:16908532 |
2026-02-14 07:54:52 | 0 | ||||
|
Eri1 homozygous homokaryon ‘a’ Resource Report Resource Website |
RRID:TSC_SD02777 | Tetrahymena thermophila | homozygous Er1 ko homokaryon ‘a’ can be mating with homozygous Er1 ko homokaryon ‘d’; coding sequences were replaced by Neo 3. Developmental delay. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | ERI1 (TTHERM_00501020) | Micronucleus: ERI1 coding replaced by neo3 Macronucleus: ERI1 coding replaced by neo3 | SD02777 | eri1::neo3/eri1::neo3; mpr1-1/mpr1-1 (eri1::neo3; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:54:51 | 0 | |||||
|
CU3044 Resource Report Resource Website |
RRID:TSC_SD00994 | Tetrahymena thermophila | Deletion on right arm of chromosome 3. | SD00994 | chx1-1/chx1-1; pmr1-1/pmr1-1; Del 3R (CHX1; pmr1-1; cy-s, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:54:52 | 0 | |||||||
|
gDRH1-KO4 A5-5A Resource Report Resource Website |
RRID:TSC_SD02139 | Tetrahymena thermophila | Neo4 KO cassette in DRH1 locus, homozygous KO in mic, mac assorted to pm-s. Two cell lines in row. Mate with D3, H7, and C10 cell lines. Homozygous heterokaryon. Gene is expressed at low level in starve and log, peak expression at 4 hr of conjugation. Somatic KO is complete, when mated they arrest after Meiosis II. Homozygous homokaryon KOs do not grow well. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | DRH1 (TTHERM_00190830) | Micronucleus: Neo4 into 5’ end of coding of DRH1 | SD02139 | drh1[∆?::neo4]/drh1[∆?::neo4] | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:54:52 | 0 | |||||
|
B1KO-2 Resource Report Resource Website |
RRID:TSC_SD01840 | Tetrahymena thermophila | Germline transformant (heterozygote). Transformed with BHAB-1 (BTU1 knockout construct) Mates with B1KO-1 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU1 (TTHERM_00348510) | Micronucleus: H4-neo replaces coding of BTU1, heterozygous | SD01840 | BTU1/btu1[∆,::H4-neo]; MPR1-1/mpr1-1 | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 PMID:9037049 |
2026-02-14 07:54:51 | 0 | ||||
|
AAB2D9-1 Resource Report Resource Website |
RRID:TSC_SD02021 | Tetrahymena thermophila | Progeny of DB6B x DB2A, co- transformed by constructs BTU1-D9 with (E431-442D) and construct of chimeric ATU1 gene, AAB2 (α-β hybrid ) See publications. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580), ATU1 (TTHERM_00558620) | Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: BTU2 replaced by bsr. BTU1 partially replaced by neo1, some replaced by BTU1-D9 with (E431-442D). Some ATU1 replaced by ATU1 with chimeric α-β hybrid tail. | SD02021 | btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]/ btu1-?[E431D,E432D,E433D,E435D,E437D,E438D,E439D,E440D,E442D]; ATU1/atu1-1[α-β hybrid tail, AAB2]; pm-r, Original BTU2 is replaced by bsr1, BTU1 coding replaced by neo1, then transformed with BTU1 with (E431-442D) and Chimeric ATU1 gene, AAB2 (α-β hybrid ), ?) | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 PMID:11864572 PMID:15254268 |
2026-02-14 07:54:52 | 0 | ||||
|
gDRH1-KO4 A5-5B Resource Report Resource Website |
RRID:TSC_SD02140 | Tetrahymena thermophila | Neo4 KO cassette in DRH1 locus, homozygous KO in mic, mac assorted to pm-s. Two cell lines in row. Mate with D3, H7, and C10 cell lines. Homozygous heterokaryon. Gene is expressed at low level in starve and log, peak expression at 4 hr of conjugation. Somatic KO is complete, when mated they arrest after Meiosis II. Homozygous homokaryon KOs do not grow well. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | DRH1 (TTHERM_00190830) | Micronucleus: Neo4 into 5’ end of coding of DRH1 | SD02140 | drh1[∆?::neo4]/drh1[∆?::neo4] | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:54:52 | 0 | |||||
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∆H1(5) Resource Report Resource Website |
RRID:TSC_SD02789 | Tetrahymena thermophila | H1 knockout obtained by microinjection mac transformant, parent is CU428. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHO1 (TTHERM_00823720) | Macronucleus: Neo2 into HHO1 locus | SD02789 | mpr1-1/mpr1-1 (hho1[∆::neo2]; MPR1; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:7606784 | 2026-02-14 07:54:51 | 0 | ||||
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IA225 Resource Report Resource Website |
RRID:TSC_SD01458 | Tetrahymena thermophila | Incomplete fission-zone formation with arrest in late-cytokinesis, with the new oral apparatus often abnormal and frequently wedged within the arrested furrow. Expressed in many cells at normal growth temperatures, near 100% at 39°. Same phenotype as the allelic IA137 stock,but with stronger expression. Submitted by Joseph Frankel, University of Iowa | CDAE (cell division arrest E) | SD01458 | cdaE-3/cdaE-3 (cdaE-3, II) | TSC, Tetrahymena Stock Center | TSC | PMID:821816 PMID:407114 |
2026-02-14 07:54:51 | 0 | |||||
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IA385 Resource Report Resource Website |
RRID:TSC_SD00643 | Tetrahymena thermophila | A mutation that causes the dorsal surface to be converted to a partial mirror-image of the ventral surface and blocks conjugation. Allelic to janA-1. | JANA (janus A) (originally reported as jan); EJA1 (enhancer of janus) | SD00643 | janA-2/janA-2; eja1-1/eja1-1 (janA-2; eja1-1; janA, eja1, II) | TSC, Tetrahymena Stock Center | TSC | PMID:1743393 | 2026-02-14 07:54:52 | 0 |
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