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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2306043
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals
References:
Synonyms:
Notes: Developed by the DEPOSITOR, this is one of the SHR substrains, CL line, which shows lower blood pressure National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2306043 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2306049
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals
References:
Synonyms:
Notes: Developed by the DEPOSITOR, this is one of the SHRSP substrains, CT line, which shows cardiac thrombosis National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2306049 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2306048
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Live Animals
References:
Synonyms:
Notes: Developed by the DEPOSITOR, this is one of the SHR substrains, CH line, which shows high blood pressure National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2306048 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60986
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Heston 1946 from Buffalo stock of H. Morris. To NIH in 1950 at F10. NIH Autoimmune Rat Model Repository and Development Center
Proper citation: RRID:RGD_60986 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60987
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Extinct
References:
Synonyms:
Notes: Milan Hypertensive Strain: Outbred Wistar rats with brother x sister mating and selection for high systolic blood pressure (Bianchi et al 1974, Barber et al, 1994).
Proper citation: RRID:RGD_60987 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67957
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Developed as strain MF by Holme and Piechuta (1979) by selective breeding of Sprague-Dawley outbred rats. Individuals were injected sub-cutaneously with egg albumin and B. pertussis vaccine i.p. then challenged with areosolised egg albumin after 14-18 days. Individuals within litters with the most severe symproms (longest duration of dyspnea) were selected and mated brother x sister. Later re-named APR (Apnea Prone Rat).
Proper citation: RRID:RGD_67957 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67959
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Outbred rats at the University of Otago Medical School, to Dept. of Surgery 1963 at F22-24. Not histocompatible with AS (Heslop 1968).
Proper citation: RRID:RGD_67959 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67958
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: University of Otago from Wistar rats imported from England in 1930. May be subline of GH, with which it is histocompatible (Heslop and Phelan 1973).
Proper citation: RRID:RGD_67958 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60991
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Dr. M. Sabourdy about 1960 from Long-Evans outbred stock. To Muhlbock, Amsterdam, and to Han in 1973. Note that other inbred strains independently derived from Long Evans stock may differ because of the outbred origin (Festing and Bender, 1984).
Proper citation: RRID:RGD_60991 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60992
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Outbred Wistar rats with brother x sister mating and selection for low systolic blood pressure as a normotensive control for MHS. (Bianchi et al 1974).
Proper citation: RRID:RGD_60992 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60995
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Recombinant inbred strain used as normotensive control in studies of hypertension.
Proper citation: RRID:RGD_60995 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60996
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: R. Sato 1950 by inbreeding Japanese albino rats.
Proper citation: RRID:RGD_60996 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60997
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Developed from stock of unstated origin by Dr. T.T. Odell, Jr. at Oak Ridge National Laboratory, Tennessee to F11, then by Dr. Darcy Wilson at the Wistar Institute, who named it DA because it expressed the 'd' blood group allele of Joy Palm, and it is 'a' agouti in colour (Wilson 1965). Inbreeding was completed in about 1965. Although Palm and Black (1971) suggest it may be related to COP, there is no real evidence that this is the case.
Proper citation: RRID:RGD_60997 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60998
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: This Copenhagen (COP) rat was an inbred strain from Curtiss 1921 at Columbia University Institute for Cancer Research.
Proper citation: RRID:RGD_60998 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=60999
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Dr. Margaret Lewis from Wistar stock, to Aptekman and Bogden 1954 at F20, to Silvers in 1958 at F31. Subsequently distributed by Silvers. Used as the inbred partner for a number of congenic strains at the major histocompatibility complex (Stark and Kren 1969). A substrain with congenital hydrocephalus due to primary aqueductal stenosis has been described by Yamada et al, (1992) Harlan Sprague Dawley Inc. Indianapolis, United States
Proper citation: RRID:RGD_60999 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10045545
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
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Notes: Original breeders are from a colony at Hadassah University Hospital, Jerusalem, Israel: Professor Cohen AM et al. initiated the Cohen diabetic (CD) rat model at the Hadassah University Hospital in the 1950s to examine the role of constitutional (genetic) and environmental (dietary) factors in the development of type 2 diabetes mellitus. Since 1996, the original colony underwent a secondary inbreeding by Dr. Sarah Zangen designated by Prof. Cohen as responsible for the Cohen diabetic (CD) rat colony.
Proper citation: RRID:RGD_10045545 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67971
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Strain developed by crossing BB/Wor rats, a lean model of type I diabetes mellitus with a Zucker fatty (fa ) rat of unstated genetic background, followed by sib mating with forced heterozygosity for the fatty gene. Thus in each generation there is a ratio of 3
Proper citation: RRID:RGD_67971 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67975
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Druckrey 1937 from a yellow, pink-eyed strain. Inbred and reduced to one pair after World War II. Crosses with Wistar stock and subsequent inbreeding led to the development of BDII. According to Druckrey (1971), strains BDIII-BDX were then developed from a cross of a single BDI x BDII mating pair, with subsequent selection for coat colour alleles. However, the strains have four different RT1 haplotypes (d, v, l and e) rather than the two that would be expected from such a cross (Stark and Zeiss 1970). The strains can _not_ be regarded as a set of recombinant inbred strains as defined by Bailey (1971), although their definition by coat colour alleles makes the set easily identifiable , and should help (but not guarantee!) to ensure authenticity. According to Druckrey (1971), all strains have a low tumour incidence, with a median life-span of 700-950 days, depending on strain.
Proper citation: RRID:RGD_67975 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=67974
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes: Zentralinstitut fur Versuchstierzucht, Hannover, from a cross between BDVII and E3, with selection for black hooded offspring.
Proper citation: RRID:RGD_67974 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10033
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Notes:
Proper citation: RRID:RGD_10033 Copy
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