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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062395
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00015446(srab-1)|WBGene00015447(srab-2)|WBGene00015448(srab-3)|WBGene00016363(srab-4)|WBGene00019091(srab-13)|WBGene00021488(srab-23)
Genomic Alteration: WBGene00015446(srab-1), WBGene00015447(srab-2), WBGene00015448(srab-3), WBGene00016363(srab-4), WBGene00019091(srab-13), WBGene00021488(srab-23)
Availability: unknown
References:
Synonyms: srab-1(yum1849) srab-2(yum1850) srab-3(yum1851) srab-4(yum1852) srab-13(yum1853) srab-23(yum1854) V; k08b5.1(yum1856) X; y41d4b.1(yum1855) IV.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062395 Copy
http://www.wormbase.org/db/get?name=WBStrain00062434
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: f49e11.2(yum2105) f57c9.6(yum2106) zc266.1(yum2107) IV.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062434 Copy
http://www.wormbase.org/db/get?name=WBStrain00062398
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00007595(tmem-145)|WBGene00009558(gpr-158)|WBGene00021362(fmil-1)
Genomic Alteration: WBGene00007595(tmem-145), WBGene00009558(gpr-158), WBGene00021362(fmil-1)
Availability: unknown
References:
Synonyms: fmil-1(yum1873) IV; gpr-158(yum1872) I; tmem-145(yum1871) t04f8.2(yum1870) X.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062398 Copy
http://www.wormbase.org/db/get?name=WBStrain00062431
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006070(str-2)|WBGene00006071(str-3)|WBGene00006232(str-193)|WBGene00006233(str-196)|WBGene00006234(str-198)|WBGene00006235(str-199)|WBGene00006236(str-200)|WBGene00006237(str-204)|WBGene00006238(str-205)
Genomic Alteration: WBGene00006070(str-2), WBGene00006071(str-3), WBGene00006232(str-193), WBGene00006233(str-196), WBGene00006234(str-198), WBGene00006235(str-199), WBGene00006236(str-200), WBGene00006237(str-204), WBGene00006238(str-205)
Availability: unknown
References:
Synonyms: str-196(yum2084) str-198(yum2085) str-199(yum2086) str-200(yum2087) str-204(yum2088) str-205(yum2089) str-193(yum2090) str-2(yum2091) str-3(yum2092) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062431 Copy
http://www.wormbase.org/db/get?name=WBStrain00062437
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00005748(srw-1)|WBGene00005749(srw-2)|WBGene00005750(srw-3)|WBGene00005751(srw-4)|WBGene00005753(srw-6)|WBGene00005754(srw-7)|WBGene00005755(srw-8)
Genomic Alteration: WBGene00005748(srw-1), WBGene00005749(srw-2), WBGene00005750(srw-3), WBGene00005751(srw-4), WBGene00005753(srw-6), WBGene00005754(srw-7), WBGene00005755(srw-8)
Availability: unknown
References:
Synonyms: srw-1(yum2124) srw-2(yum2125) srw-3(yum2126) srw-4(yum2127) srw-6(yum2128) srw-7(yum2129) srw-8(yum2130) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062437 Copy
http://www.wormbase.org/db/get?name=WBStrain00062438
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006186(str-139)|WBGene00006187(str-138)|WBGene00006188(str-140)|WBGene00006190(str-143)|WBGene00006191(str-144)
Genomic Alteration: WBGene00006186(str-139), WBGene00006187(str-138), WBGene00006188(str-140), WBGene00006190(str-143), WBGene00006191(str-144)
Availability: unknown
References:
Synonyms: str-138(yum2131) str-139(yum2132) str-140(yum2133) str-143(yum2134) str-144(yum2135) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062438 Copy
http://www.wormbase.org/db/get?name=WBStrain00062538
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00013739(spin-4)
Genomic Alteration: WBGene00013739(spin-4)
Availability: unknown
References:
Synonyms: spin-4(knu1099) Ill.
Notes: knu1099 is an engineered 7437 bp deletion in spin-4. Flanking sequences immediately outside of the region deleted ares: 5 flank (forward strand), 5- GTT CGG TGG AGC GCG CCT GCG -3; 3 flank (reverse strand), 5- GTC TGT GTT GCT GTT CCT CAT -3. In between these flanking sequences, a three-frame stop as well as a unique primer-binding sequence were inserted in place of the deleted sequence. This strain may not be distributed to commercial or for-profit entities without prior written permission from In Vivo Biosystems. Please contact support@invivobiosystems.com for more information. Reference: Flora Y & Bohnert KA. Dev Biol. 2023 Dec:504:137-148. doi: 10.1016/j.ydbio.2023.09.013. PMID: 37805103.|"Made_by: In Vivo Biosystems"
Proper citation: RRID:WB-STRAIN:WBStrain00062538 Copy
http://www.wormbase.org/db/get?name=WBStrain00062490
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00005118(srd-40)|WBGene00005119(srd-41)|WBGene00005120(srd-42)|WBGene00005121(srd-43)|WBGene00005122(srd-44)|WBGene00005127(srd-49)
Genomic Alteration: WBGene00005118(srd-40), WBGene00005119(srd-41), WBGene00005120(srd-42), WBGene00005121(srd-43), WBGene00005122(srd-44), WBGene00005127(srd-49)
Availability: unknown
References:
Synonyms: srd-40(yum2478) srd-41(yum2479) srd-42(yum2480) srd-43(yum2481) srd-44(yum2482) srd-49(yum2483) X.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062490 Copy
http://www.wormbase.org/db/get?name=WBStrain00062499
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00008814(srz-1)|WBGene00011876(srz-6)|WBGene00015175(srz-4)|WBGene00021722(srz-5)|WBGene00022481(srz-9)|WBGene00022483(srz-8)|WBGene00023411(srz-3)
Genomic Alteration: WBGene00008814(srz-1), WBGene00011876(srz-6), WBGene00015175(srz-4), WBGene00021722(srz-5), WBGene00022481(srz-9), WBGene00022483(srz-8), WBGene00023411(srz-3)
Availability: unknown
References:
Synonyms: srz-1(yum2552) V; srz-3(yum2553) srz-4(yum2554) I; srz-5(yum2555) srz-6(yum2556) II; srz-8(yum2557) srz-9(yum2558) III.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062499 Copy
http://www.wormbase.org/db/get?name=WBStrain00062533
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00022284(glb-33)
Genomic Alteration: WBGene00022284(glb-33)
Availability: unknown
References:
Synonyms: glb-33(yum2917) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062533 Copy
http://www.wormbase.org/db/get?name=WBStrain00062497
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006280(str-254)|WBGene00006281(str-255)|WBGene00006282(str-256)|WBGene00006283(str-257)|WBGene00006284(str-258)|WBGene00006286(str-260)|WBGene00006287(str-261)|WBGene00006288(str-262)
Genomic Alteration: WBGene00006280(str-254), WBGene00006281(str-255), WBGene00006282(str-256), WBGene00006283(str-257), WBGene00006284(str-258), WBGene00006286(str-260), WBGene00006287(str-261), WBGene00006288(str-262)
Availability: unknown
References:
Synonyms: str-255(yum2534) str-256(yum2535) str-257(yum2536) str-260(yum2537) str-254(yum2538) str-261(yum2539) str-262(yum2540) y19d10a.1(yum2541) str-258(yum2542) y19d10a.2(yum2543) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062497 Copy
http://www.wormbase.org/db/get?name=WBStrain00062536
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00008598(spin-3)
Genomic Alteration: WBGene00008598(spin-3)
Availability: unknown
References:
Synonyms: spin-3(knu1020[spin-3::mCherry::loxP::HygR::loxP]) X.
Notes: Made_by: In Vivo Biosystems|"mCherry tag inserted at the C-terminus of the endogenous spin-3 locus via CRISPR/Cas9 engineering. This strain may not be distributed to commercial or for-profit entities without prior written permission from In Vivo Biosystems. Please contact support@invivobiosystems.com for more information. Reference: Villalobos TV, et al. Nat Aging. 2023 Sep;3(9):1091-1106. PMID: 37580394."
Proper citation: RRID:WB-STRAIN:WBStrain00062536 Copy
http://www.wormbase.org/db/get?name=WBStrain00062537
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00013739(spin-4)
Genomic Alteration: WBGene00013739(spin-4)
Availability: unknown
References:
Synonyms: spin-4(knu1071[spin-4::mCherry]) Ill.
Notes: Made_by: In Vivo Biosystems|"mCherry tag inserted at the C-terminus of the endogenous spin-4 locus via CRISPR/Cas9 engineering. This strain may not be distributed to commercial or for-profit entities without prior written permission from In Vivo Biosystems. Please contact support@invivobiosystems.com for more information. Reference: Villalobos TV, et al. Nat Aging. 2023 Sep;3(9):1091-1106. PMID: 37580394."
Proper citation: RRID:WB-STRAIN:WBStrain00062537 Copy
http://www.wormbase.org/db/get?name=WBStrain00062534
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: twnEx185.
Notes: twnEx185 [mec-7p::MTS::roGFP + mec-7p::TOMM20::mCherry + ttx-3p::GFP]. Pick animals with GFP expression in head neurons (AIY) to maintain. roGFP can be used to monitor redox status of the mitochondrial matrix in the six touch receptor neurons: the oxidation-reduction status of mitochondrial matrix can be monitored with roGFP, a GFP variant that increases brightness in a more oxidized environment. The mitochondrial outer membrane in these neurons are marked by mCherry. Reference: Jiang HC, et al. Proc Natl Acad Sci USA. 2015 Jul 14;112(28):8768-73. doi: 10.1073/pnas.1501831112. PMID: 26124107. [NOTE: twnEx185 is incorrectly described as carrying myo-2p::GFP in the reference publication. The correct co-injection marker is ttx-3::GFP.]
Proper citation: RRID:WB-STRAIN:WBStrain00062534 Copy
http://www.wormbase.org/db/get?name=WBStrain00062535
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00008033(spin-2)
Genomic Alteration: WBGene00008033(spin-2)
Availability: unknown
References:
Synonyms: spin-2(knu1018[spin-2::mCherry::loxP::HygR::loxP]) IV.
Notes: Made_by: In Vivo Biosystems|"mCherry tag inserted at the C-terminus of the endogenous spin-2 locus via CRISPR/Cas9 engineering. This strain may not be distributed to commercial or for-profit entities without prior written permission from In Vivo Biosystems. Please contact support@invivobiosystems.com for more information. Reference: Villalobos TV, et al. Nat Aging. 2023 Sep;3(9):1091-1106. PMID: 37580394."
Proper citation: RRID:WB-STRAIN:WBStrain00062535 Copy
http://www.wormbase.org/db/get?name=WBStrain00062529
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: f54e2.5(yum2833) c34b4.5(yum2834)f54e2.9(yum2835) f57b1.1(yum2836) f57b1.9(yum2837) f58f6.5(yum2838) f58f6.6(yum2839)t09e8.4(yum2840) y51a2b.2(yum2841) zc196.8(yum2842) zc196.9(yum2843) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062529 Copy
http://www.wormbase.org/db/get?name=WBStrain00062528
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: c27h5.6(yum2827) c50e3.7(yum2828) y75b8a.34(yum2829) c50e3.9(yum2830) f42a6.1(yum2831) y55h10a.2(yum2832) II.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062528 Copy
http://www.wormbase.org/db/get?name=WBStrain00062484
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00005735(srv-24)|WBGene00005736(srv-25)|WBGene00005737(srv-26)|WBGene00005738(srv-27)|WBGene00005739(srv-28)|WBGene00005740(srv-29)|WBGene00005741(srv-30)|WBGene00005742(srv-31)|WBGene00005743(srv-32)|WBGene00005744(ops-1)
Genomic Alteration: WBGene00005735(srv-24), WBGene00005736(srv-25), WBGene00005737(srv-26), WBGene00005738(srv-27), WBGene00005739(srv-28), WBGene00005740(srv-29), WBGene00005741(srv-30), WBGene00005742(srv-31), WBGene00005743(srv-32), WBGene00005744(ops-1)
Availability: unknown
References:
Synonyms: srv-24(yum2423) srv-25(yum2424) srv-26(yum2425) srv-27(yum2426) srv-28(yum2427) srv-29(yum2428) srv-30(yum2429) srv-31(yum2430) srv-32(yum2431) ops-1(yum2432) IV.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062484 Copy
http://www.wormbase.org/db/get?name=WBStrain00062482
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006260(str-229)|WBGene00006261(str-230)|WBGene00006262(str-231)|WBGene00006263(str-232)|WBGene00006264(str-233)|WBGene00006265(str-236)
Genomic Alteration: WBGene00006260(str-229), WBGene00006261(str-230), WBGene00006262(str-231), WBGene00006263(str-232), WBGene00006264(str-233), WBGene00006265(str-236)
Availability: unknown
References:
Synonyms: str-229(yum2409) str-230(yum2410) str-231(yum2411) str-232(yum2412) str-233(yum2413) str-236(yum2414) c06b3.1(yum2415) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062482 Copy
http://www.wormbase.org/db/get?name=WBStrain00062483
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00005028(sra-2)|WBGene00005029(sra-3)|WBGene00005030(sra-4)|WBGene00005032(sra-6)|WBGene00005033(sra-7)|WBGene00005034(sra-8)|WBGene00005035(sra-9)
Genomic Alteration: WBGene00005028(sra-2), WBGene00005029(sra-3), WBGene00005030(sra-4), WBGene00005032(sra-6), WBGene00005033(sra-7), WBGene00005034(sra-8), WBGene00005035(sra-9)
Availability: unknown
References:
Synonyms: sra-2(yum2416) sra-3(yum2417) sra-4(yum2418) sra-6(yum2419) sra-7(yum2420) sra-8(yum2421) sra-9(yum2422) II.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062483 Copy
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